Effects of valproate on the entry of inert hydrophilic markers and expression of tight junction associated genes in the neonatal brain and choroid plexus of a rat model of epilepsy... by Fiona Qiu, Katarzyna M. Dziegielewska, Mark D. Habgood, Yifan Huang, Norman R. Saunders

“…After 5 min, plasma, CSF and brain samples were collected for radioactivity measurement. …”
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A nationwide analysis of geriatric proximal humerus fractures: trends, outcomes, and cost by Purvi P Patel, Teresa Cheng, Michael J Anstadt, Richard P Gonzalez, Kevin Galicia, John Kubasiak

“…This retrospective study compares annual trends, patient outcomes, and hospital costs between operatively and non-operatively managed geriatric PHF.Methods The Healthcare Cost and Utilization Project Nationwide Inpatient Sample was queried from 2012 to 2015. …”
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Therapeutic Role of Additional Mirror Therapy on the Recovery of Upper Extremity Motor Function after Stroke: A Single-Blind, Randomized Controlled Trial by Xin Wen, Li Li, Xuelian Li, Huanghong Zha, Zicai Liu, Yang Peng, Xuejin Liu, Huiyu Liu, Quan Yang, Jing Wang

“…To invest the effects of additional mirror therapy in improving upper limb motor function and activities of daily living in acute and subacute stroke patients, and further explore the effects of other factors on the efficacy of MT. Methods. Participants who presented with unilateral upper extremity paralysis due to a first ischemic or hemorrhagic stroke were included in the study. …”
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Retinal Vascular Response to Hyperoxia in Patients with Diabetes Mellitus without Diabetic Retinopathy by Hamid Safi, Ramin Nourinia, Sare Safi, Ehsan Hadian, Bahareh Kheiri, Hamid Ahmadieh

“…To evaluate the retinal vascular response to hyperoxia in patients with diabetes at the preclinical stage of diabetic retinopathy (DR) and to quantify the changes in comparison with normal subjects using optical coherence tomography angiography (OCTA). Methods. In this prospective study, 40 eyes of 20 participants comprising 10 diabetic patients with no diabetic retinopathy (NDR) and 10 normal subjects were recruited. …”
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Assessing ChatGPT-4’s performance on the US prosthodontic exam: impact of fine-tuning and contextual prompting vs. base knowledge, a cross-sectional study by Mahmood Dashti, Farshad Khosraviani, Tara Azimi, Delband Hefzi, Shohreh Ghasemi, Amir Fahimipour, Niusha Zare, Zohaib Khurshid, Syed Rashid Habib

“…The aim is to determine whether fine-tuning improves the AI’s accuracy in answering specialized questions. Methods An official sample questions from the 2021 US National Prosthodontic Resident Mock Exam was used, obtained from the American College of Prosthodontists. …”
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Sociodemographic and clinical characteristics associated with overdose among patients with a substance-related diagnosis in the emergency department of Southern California by Brian Maila, María Luisa Zúñiga, Carla Marienfeld

“…We investigated the sociodemographic and clinical characteristics associated with drug overdoses among patients with substance-related diagnoses (SRD) in a Southern California healthcare system’s ED. Methods A cross-sectional study employed EPIC electronic medical records from a sample of 13,477 adults (18–90 years of age) diagnosed with an SRD ICD-10 classification and had an ED encounter within the UCSD Health system in Southern California during the period from January 1, 2020, to December 31, 2023. …”
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Expansion of social protection is necessary towards zero catastrophic costs due to TB: The first national TB patient cost survey in the Philippines. by Jhiedon L Florentino, Rosa Mia L Arao, Anna Marie Celina Garfin, Donna Mae G Gaviola, Carlos R Tan, Rajendra Prasad Yadav, Tom Hiatt, Fukushi Morishita, Andrew Siroka, Takuya Yamanaka, Nobuyuki Nishikiori

“…To assess patient costs related to TB care and the proportion of TB-affected households that faced catastrophic costs, the Philippines National TB Programme (NTP) conducted a national TB patient cost survey in 2016-2017.<h4>Methods</h4>A cross-sectional survey of 1,912 TB patients taking treatment in health facilities engaged with the NTP. …”
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SIGLEC1 has the potential to be an immune-related prognostic indicator in colon adenocarcinoma: a study based on transcriptomic data and Mendelian randomization analysis by Jue Gu, Yaxuan Wang, Hui Zhang, Haijuan Gu, Haixia Zhu

“…There are currently no specific studies indicating the mechanism of action of TME in COPD patients. Methods The percentage of tumor-infiltrating immune cells (TIC) in 512 COAD cases from The Cancer Genome Atlas (TCGA) database was calculated using CIBERSORT and ESTIMATE. …”
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Effect of a Single Dose of Metoclopramide on Gastric Volume in Fasting Diabetic Patients Measured using Ultrasonography: A Randomised Controlled Trial by Shwetha K Mudalagirigowda, Madhu Srinivasaiah, Jyothi Bramhachar

“…Aim: To evaluate the effect of metoclopramide on GV in diabetic patients using Ultrasonography (USG). Materials and Methods: This prospective randomised double-blinded study was conducted in the Department of Anaesthesiology, Chandramma Dayanand Sagar Institute of Medical Education and Research (a tertiary care centre), Bengaluru, Karnataka, India between March 2023 and March 2024. …”
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Prevalence of Mitral Valve Prolapse Among Individuals with Pectus Excavatum: A Systematic Review and Meta-Analysis by Andrea Sonaglioni, Antonino Bruno, Alessio Polymeropoulos, Gian Luigi Nicolosi, Michele Lombardo, Paola Muti

“…The present systematic review and meta-analysis has been primarily designed to summarize the main findings of these studies and to estimate the overall prevalence of MVP among PE individuals. <b>Methods</b>: All imaging studies assessing the prevalence of MVP in PE individuals vs. healthy controls, selected from PubMed and EMBASE databases, were included. …”
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Ultrasound biomicroscopic imaging analysis of lens position and stability in acute and chronic angle-closure glaucoma by Zhiying Yu, Xinyu Wang, Haitao Wang, Jing Han, Jing Fu, Licun Wang, Ling Wang

“…IntroductionThis study aimed to compare the characteristics and differences in lens position and stability in patients with acute and chronic angle-closure glaucoma (ACG) using ultrasound biomicroscopy (UBM) to provide a basis for selecting treatment regimens for primary ACG (PACG).MethodsThis prospective study included 82 eyes of patients with PACG, of which, 45 eyes with acute PACG (APACG), 37 with chronic PACG (CPACG). …”
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VISUALIZATION OF SINUS NODE ARTERIES BY MULTISLICE SPIRAL COMPUTED TOMOGRAPHY CORONARY ANGIOGRAPHY by L. A. Bockeria, V. N. Makarenko, L. A. Yurpol’skaya, S. A. Alexandrova, M. A. Shlyappo

“…Objective: to assess the capabilities of multislice spiral computed tomography coronary angiography (MSCT-CA) to visualize the anatomy of the sinus node artery (SNA). Material and methods. The retrospective analysis of coronary artery examinations covered 46 patients with the referral diagnosis of coronary heart disease. …”
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GPX3 promotes cisplatin resistance in TNBC by manipulating ROS-TGFB1-ZEB2 by Qingyi Hu, Qianzhi Chen, Wen Yang, Anwen Ren, Jie Tan, Tao Huang

“…Investigating the mechanism underlying TNBC’s resistance to platinum-based chemotherapy and identifying new therapeutic targets are urgent priorities. Methods The expression level of GPX3, cisplatin sensitivity, and ROS production were compared across three TNBC cell lines to elucidate the relationship between GPX3 and platinum resistance. …”
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Exploring the Views of Dermatologists, General Practitioners, and Melanographers on the Use of AI Tools in the Context of Good Decision-Making When Detecting Melanoma: Qualitative... by Brad Partridge, Nicole Gillespie, H Peter Soyer, Victoria Mar, Monika Janda

“…A priority for clinicians is the conservation of good clinical acumen, and our study encourages a more focused engagement with users about the precise way to incorporate AI into the clinical decision-making process for melanoma detection.…”
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Integrated proteomics and metabolomics network analysis across different delivery modes in human pregnancy: a pilot study by Yun Huang, Yanyan Ni, Yu Meng, Xiaojing Zeng, Xiaoqing He, Lin Zhang, Jun Zhang

“…However, it remains unclear whether protein and metabolite differences across different delivery modes may underlie child development. Methods A cohort comprising 16 spontaneous onset vaginal delivery (VD), 16 prelabor cesarean delivery on maternal request (CS), and 8 intrapartum cesarean section (Intra_CS) women were analyzed using label-free proteomic and untargeted metabolomics assays on amniotic fluid and cord blood samples, respectively. …”
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The association between multimorbidity and food insecurity among US parents, guardians, and caregivers by Claire E. Branley, Melissa Goulding, Mayra Tisminetzky, Stephenie C. Lemon

“…To fill this gap, we examined the association between multimorbidity and food insecurity among U.S. parents. Methods Cross-sectional data from 2019 to 2022 of the National Health Interview Survey were analyzed. …”
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Spatial transcriptomic analysis across histological subtypes reveals molecular heterogeneity and prognostic markers in early‐stage lung adenocarcinoma by Hua Geng, Wenhao Zhou, Haitao Luo, Jiaqian Wang, Shixiong Li, Congcong Song, Yujie Zhao, Meilin Xu

“…Currently, the correlation between molecular and histologic features remains poorly understood. Methods Formalin‐fixed paraffin‐embedded (FFPE) samples were collected from patients with primary early‐stage lung adenocarcinoma, encompassing three histologic subtypes: well‐differentiated, moderately differentiated, and poorly differentiated. …”
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Associations of Cerebral Small Vessel Disease and Chronic Kidney Disease in Patients With Acute Ischemic Stroke by Rentang Bi, Yanhao Wei, Pengcheng Li, Haokun Peng, Mohammad Alizadeh, Bo Hu, Yanan Li

“…In particular, there is a lack of research focusing on patients with acute ischemic stroke, a key area that could provide important insights into the brain–kidney connection. Methods AND RESULTS We established a large‐sample size, multicenter prospective cohort study (SMART [Cerebral Small Vascular Disease Registry Multicenter Clinical Trial]) across 13 subcenters in central China. …”
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Food Safety: Pathological and Biochemical Responses of Nile Tilapia (<i>Oreochromis niloticus)</i> to Parasitological Infestation and Heavy Metals Pollution in Aquaculture System,... by Muslimah N. Alsulami, Sarah Khaled Baowidan, Rabab M. Aljarari, Haleema H. Albohiri, Samar A. Khan, Elham Ali Elkhawass

“…Objective: The study aims to assess the overall safety of cultured tilapias in Jeddah City, Saudi Arabia by assessing the impact of infection and anthropogenic pollution on farmed tilapias based on fish sex, body weight, length, and heavy metals contamination. Materials and methods: A total of 111 fish were collected from an aquaculture farm in Hada Al-Sham, Jeddah, Saudi Arabia. …”
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Clinicopathological features and differential diagnosis of AIDS with CMV infection by ZENG Dong, SONG Shu, YANG Yuexiang, XU Jingjing, GUO Wenjuan, ZHENG Ye, SHI Yuhan, FENG Yanling

“…Result The main symptoms of the patients were fever, nausea and vomiting, gastric discomfort, abdominal pain and diarrhea, while a few cases presented with hematemesis, hematochezia, cough, and hemoptysis. Tissue samples from 32 cases were obtained via gastrointestinal endoscopic biopsies, including 10 cases with biopsies from more than 2 sites. 2 cases were from lymph nodes, and 1 case each from skin, submandibular gland, lung, and perianal biopsies. …”
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