The Impact of Rapid Molecular Diagnostics for Influenza on Antibiotic Stewardship in the Emergency Department—An Observational Retrospective Study by Elisa Roth, Marco Cattaneo, Yvonne Hollenstein, Maja Weisser, Stefano Bassetti, Sarah Tschudin Sutter, Roland Bingisser, Christian H. Nickel, Adrian Egli

“…We explored whether a rapid influenza-specific polymerase chain reaction (PCR) assay reduced antibiotic use in an emergency room before the COVID-19 pandemic. Methods: We conducted an observational retrospective study of patients with RTI symptoms treated in the ER of the University Hospital Basel from September 2014 to June 2015. …”
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Pelvic floor‐related sexual functioning in the first 24 months postpartum: Findings of a large cross‐sectional study by Carsten Hagenbeck, Jan Kössendrup, Johannes Soff, Fabinshy Thangarajah, Nadine Scholten

“…Material and Methods We conducted a cross‐sectional online survey and recruited via social media women up to 24 months after birth of their last child. …”
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From Cell Lines to Patients: Dissecting the Proteomic Landscape of Exosomes in Breast Cancer by Aleksei Shefer, Lyudmila Yanshole, Ksenia Proskura, Oleg Tutanov, Natalia Yunusova, Alina Grigor’eva, Yuri Tsentalovich, Svetlana Tamkovich

“…Since the diagnosis and treatment of BC have been improved substantially with exosomes, in this study, we isolated breast carcinoma cell-derived exosomes, primary endotheliocyte-derived exosomes, and blood exosomes from BC patients (BCPs) in the first stage of disease and investigated their proteomic profiles. <b>Methods</b>: Exosomes were isolated from the samples by ultrafiltration and ultracentrifugation, followed by mass spectrometric and bioinformatics analyses of the data. …”
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Trends in medically serious suicide attempts before and after COVID-19: a four-year retrospective analysis (2018–2022) by Anna Beneria, Luis Marte, Marta Quesada-Franco, Sara García-González, Damià Restoy, Citlalli Pérez-Galbarro, Olga Santesteban-Echarri, Rosa Ramos, Josep Antoni Ramos-Quiroga, María Dolores Braquehais

“…Several studies have analyzed the trends in suicide attempts (SA) before and after the onset of the pandemic, but few studies focus on the impact of the pandemic on medically serious suicide attempts (MSSA). Methods Participants were 385 hospitalized individuals ≥ 16 years old who made MSSA identified retrospectively through a review of e-medical records between 2018 and 2022 (“pre-COVID-19” and “COVID” periods). …”
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People Who Die by Suicide Without Receiving Mental Health Services: A Systematic Review by Samantha Tang, Natalie M. Reily, Andrew F. Arena, Philip J. Batterham, Alison L. Calear, Gregory L. Carter, Andrew J. Mackinnon, Helen Christensen

“…Identifying the characteristics of people who die by suicide without receiving services, often with a fatal first attempt, is crucial to reduce suicide rates through guiding improvements to service pathways and “just in time” interventions.MethodsIn this systematic review, PsycInfo, PubMed, CINAHL, and Web of Science were searched for peer-reviewed articles published from 1980 to 1st March 2021. …”
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Promoting daily physical activity in Norway as a FYSAK school: a comparative longitudinal study of lower secondary school pupil by Ingeborg Barth Vedøy, Knut Ragnvald Skulberg, Patrick Foss Johansen, Hege Eikeland Tjomsland, Hege Eikeland Tjomsland, Miranda Thurston

“…The paper addresses the following research question: what impact does the FYSAK model have on pupils' PA patterns over time?MethodsThe paper draws on device-measured PA data from a three-year (2016–2018) longitudinal study of lower secondary school pupils from 11 schools in Norway, of which one was a FYSAK school. …”
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Kidnapping-Induced Trauma and secondary stress in armed conflicts: a comparative study among women in hostage families, volunteers, and the General Population by Shahar Livne, Ilana Feldblum, Sara Kivity, Naama Shamir-Stein, Einat Brand, Shir Cohen, Eran Rotman, Hagai Levine, Mor Saban

“…In this study we aimed to quantify changes in modifiable health behaviors and well-being among women in hostage families and hostage crisis volunteers versus the general female population within the first two months of the 2023 Israel-Hamas war. Methods A cross-sectional online survey was conducted on 318 Hebrew-speaking women aged 18–75 in Israel comparing: (1) a general population sample (n = 245); (2) hostage crisis volunteers (n = 40); and (3) hostage family members (n = 33). …”
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The impact of serum neuregulin 4 (NRG-4) levels on non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis by Mohammad Amin Tapak, Smko Rashidian Glolan, Yousef Moradi

“…However, it’s essential to note that further research with larger sample sizes and more accurate study designs is needed to corroborate these findings and establish the clinical utility of Nrg4 as a biomarker in the management of NAFLD.…”
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Detecting Conversation Topics in Recruitment Calls of African American Participants to the All of Us Research Program Using Machine Learning: Model Development and Validation Study by Priscilla Pemu, Michael Prude, Atuarra McCaslin, Elizabeth Ojemakinde, Christopher Awad, Kelechi Igwe, Anny Rodriguez, Jasmine Foriest, Muhammed Idris

“…By examining these interactions, we aim to provide insights that can improve engagement strategies and recruitment practices for underrepresented groups in biomedical research. MethodsOur study design was an observational, retrospective approach using machine learning for content analysis. …”
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Lifestyle Advice Combined with Personalized Estimates of Genetic or Phenotypic Risk of Type 2 Diabetes, and Objectively Measured Physical Activity: A Randomized Controlled Trial. by Job G Godino, Esther M F van Sluijs, Theresa M Marteau, Stephen Sutton, Stephen J Sharp, Simon J Griffin

“…We examined the effect of communicating an estimate of genetic or phenotypic risk of type 2 diabetes in a parallel group, open, randomized controlled trial.<h4>Methods and findings</h4>We recruited 569 healthy middle-aged adults from the Fenland Study, an ongoing population-based, observational study in the east of England (Cambridgeshire, UK). …”
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Adolescent firearm injury trends at a Level I trauma center in Washington State, USA, 2011–2021 by Erika Marts, Frederick P. Rivara, N. Jeanie Santaularia, Ali Rowhani-Rahbar

“…Methods This retrospective cohort study used data from a Level I Trauma Center and death records to examine adolescent firearm injury trends in King County, Washington from 2011 to 2021. …”
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Sedentary behaviors, physical activity, and risk of allergic rhinitis and asthma: evidence from cohort and Mendelian randomization studies by Xiaoyu Wang, Yaya Gao, Lin Lou, Wenjie Yang, Wei Xu, Yu Zhao, Jianjun Ren

“…This study aimed to examine whether different movement behaviors are risk factors for AR and asthma based on epidemiological and genetic evidence, and to characterize these associations in diverse populations. Methods Based on information of questionnaires and registrations provided by UK Biobank, and large-scale GWAS (Genome-Wide Association Study) data, we designed a cohort study with a follow-up period exceeding 11 years and two-sample Mendelian randomization (MR) analysis to explore the causal associations between movement behaviors (SB and PA) and AR and asthma. …”
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Polymorphisms of the KCNS1, COMT and OPRM1 genes and development of postoperative pain in patients with osteoarthritis who underwent total knee or hip replacement by K. E. Glemba, I. A. Guseva, A. E. Karateev, M. A. Makarov, E. Yu. Samarkina, N. V. Konovalova, D. A. Varlamov

“…Further studies of the genetic predisposition to POP are required on more clinical material.…”
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Increased prevalence of obstructive sleep apnea in women diagnosed with endometrial or breast cancer. by Ayey Madut, Veronika Fuchsova, Hong Man, Shabeel Askar, Ritu Trivedi, Elisabeth Elder, Christine L Clarke, Gerard Wain, Alison Brand, Anna DeFazio, Terence Amis, Kristina Kairaitis

“…The aim of this study was to measure OSA in women with breast (BC) or endometrial cancer (EC) and associations with clinico-pathological tumor variables.<h4>Methods and findings</h4>In a cross sectional study, women with BC (12 months) or EC (3 months) post-diagnosis were recruited from cancer clinics. …”
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The assessment of the cytotoxic activity of 2-(1,1-dimethyl-1H-benzo[e]indolin-2-yl)-5,6,7-trichloro-1,3-tropolone against the human glioblastoma U87 MG cell line by D. V. Khodakova, N. S. Kuznetsova, S. Yu. Filippova, A. S. Goncharova, A. V. Galina, S. V. Gurova, E. A. Gusakov, Yu. A. Sayapin, E. E. Rostorguev

“…To study the cytotoxic effect of 2-(1,1-dimethyl-1H-benzo[e]indolin-2-yl)-5,6,7-trichloro-1,3-tropolone (JO-122 (2)) on the U87 MG cell line.Materials and methods. The investigation of the cytotoxic effect of synthesized tropolone JO-122 (2) was performed using the standard MTT colorimetric assay on the human glioblastoma cell line U87 MG. …”
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CHANGES IN THERMALLY STIMULATED CONDUCTIVITY OF CsPbBr3 AND CsPbCl3 CRYSTALS EXPOSED TO X-RAY IRRADIATION by Bohdan Pavlyk, Roman Lys, Roman Gamernyk, Mykola Goydalo

“…However, an unsolved problem is the degradation of these perovskites under the influence of external factors. Materials and Methods. This study investigates monocrystals of perovskites CsPbBr3 and CsPbCl3 subjected to X-ray irradiation. …”
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Prevalence of xerostomia in patients with type 2 diabetes mellitus: a systematic review and meta-analysis by Shuqi Huang, Xin Zeng, Sicheng Deng, Sixiu He, Fan Liu

“…Therefore, the present study aimed to synthesize results from existing research to investigate the prevalence of xerostomia in T2DM patients. Methods A comprehensive search was conducted in November 2024 across four databases (PubMed, Scopus, Embase, and Web of Science). …”
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Deciphering Salivary Microbiome Signature in Pediatric Inflammatory Bowel Disease by Dr. Farah Al Marzooq, Ms Ghaidaa Mesto

“…Additionally, changes in the oral microbiome of IBD patients over time in response to treatment are examined. Methods: Seventy-eight participants were recruited, including 26 CD patients, 26 UC patients, and 26 HC over a one-year period. …”
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Relevance of High Glycemic Index Breakfast for Heart Rate Variability among Young Students with Early and Late Chronotypes by Bettina Krueger, Bianca Stutz, Rasmus Jakobsmeyer, Claus Reinsberger, Anette Buyken

“…Similarly, chronotype-specific morning plasma melatonin levels could be mechanistically relevant for HRV changes following early high-GI breakfasts, as melatonin seems to influence glucose tolerance. Methods: Subjects with earlier (N = 22) and later chronotypes (N = 23) were asked to consume an intervention meal with a GI = 72 in the morning (7 a.m.). …”
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Improvements in health-related quality of life are maintained long-term in patients prescribed medicinal cannabis in Australia: The QUEST Initiative 12-month follow-up observationa... by Margaret-Ann Tait, Daniel S J Costa, Rachel Campbell, Leon N Warne, Richard Norman, Stephan Schug, Claudia Rutherford

“…<h4>Aims</h4>Since 2016, more than one million new patients with chronic health conditions have been prescribed medicinal cannabis in Australia. …”
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