Type of menopause, age of menopause and cardiovascular disease: a cross-sectional study based on data from Rafsanjan cohort study by Zahra Jamali, Parvin Khalili, Fatemeh Ayoobi, Hajar Vatankhah, Ali Esmaeili-Nadimi, Faezeh Esmaeili Ranjbar, Mahboubeh Vatanparast

“…A sample of 1767 postmenopausal women were included. …”
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TRANSCRIPTOMIC ANALYSIS OF MELANOMA CELLS EXTRACTED FROM DIFFERENT SITES OF THE PRIMARY TUMOR by M. B. Aksenenko, A. V. Komina, N. V. Palkina, A. S. Averchuk, Yu. A. Rybnikov, Yu. A. Dyhno, T. G. Ruksha

“…Treatment of malignant tumors requires an individual approach to choose the most appropriate treatment regimen.The purpose of the study was to evaluate differences in melanoma tissue samples obtained from different parts of one patient’s primary tumor at the transcriptomic level.Material and Methods. …”
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Circulating Tfh cells and Tfr cells in papillary thyroid carcinoma and their diagnostic potential by Heng Zhang, Yiwen Yu, Minglei Jiang, Renquan Lu, Lin Guo

“…Objective: This study aim to explore the alterations of circulating T follicular helper (Tfh) and T follicular regulatory (Tfr) cells in the peripheral blood of patients with papillary thyroid carcinoma (PTC), assess their association with PTC and the influence on B cells, and evaluate their diagnostic potential. Methods: Peripheral blood samples were collected from 76 newly diagnosed PTC patients and 21 matched healthy controls between June 2023 and June 2024. …”
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Potential applications of gene expression profiles obtained from circulating extracellular vesicles in breast cancer by Aritra Gupta, Siddharth Bhardwaj, Sayan Ghorai, Rosina Ahmed, Sanjit Agarwal, Geetashree Mukherjee, Kartiki V. Desai

“…A total of 84 samples were studied. Results: RNA-seq data from 500 μl serum samples yielded more than 17000 genes, of which 320 were DEGs (adjusted p value ≤ 0.05) between EV-C and EV-H samples. …”
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Impacts of Chelated Iron Supplement with Organic Acid and Amino Acid on Growth Performance, Nutrient Digestibility, Feeding Behaviors, and Blood Parameters in Suckling Calves by Mahdi Ghavidel, Abdolhakim Toghdory, Taghi Ghoorchi, Mohammad Asadi

“…To prepare plasma, blood samples were centrifuged at 3000 rpm for 10 min, and plasma samples were transferred to -20 °C until analysis. …”
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LATE RENAL GRAFT REJECTION: PATHOLOGY AND PROGNOSIS by E.S. Stolyarevich, L.Y. Artyukhina, I.G. Kim, L.G. Kurenkova, N.A. Tomilina

“…In long-term allograft biopsy C4d positivity is more haracteristic for chronic rejection than for acute rejection. …”
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Human papillomavirus (HPV) infection and liquid-based cytologic tests among cervical screening participants in Shannan City, Tibet, China, during 2021–2022 by Dilu Feng, Yuwei Yao, Xiaowu Zhu, Jun Chen, Yeshe Lhamo, Lamu Baima, Hongbo Wang, Qiyue Wang

“…This is the first large-scale cervical cytology screening study conducted in the southern region of the province. Methods Between January 2021 and December 2022, 15,493 women participated in HPV genotype testing, and 16,775 women underwent ThinPrep cytologic tests. …”
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Green synthesis and characterization of NiO/Hydroxyapatite nanocomposites in the presence of peppermint extract and investigation of their antibacterial activities against Pseudomo... by Ali Shakerimoghaddam, Hayder Jihad Majeed, Ali Jawad Hashim, May Jaleel Abed, Layth S. Jasim, Masoud Salavati-Niasari

“…As a result of the interesting structural properties of nanomaterials, nanoscience-based methods have emerged as promising ways to increase the movement of existing antimicrobials. …”
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Development of a machine learning-derived dendritic cell signature for prognostic stratification in lung adenocarcinoma by Fang Zhou, Fang Zhou, Meng Wang, Meng Wang, Zheng Wang, Zheng Wang, Wei Li, Wei Li, Xike Lu, Xike Lu

“…While dendritic cells (DCs) are essential mediators of antitumor immunity, their transcriptional diversity and prognostic value in LUAD remain underexplored.MethodsWe constructed a cellular atlas by integrating single-cell RNA sequencing (scRNA-seq) data from LUAD and normal tissues, emphasizing dendritic cells. …”
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Gardasil® as adjunctive therapy for respiratory papillomatosis at Red Cross Children’s Hospital, Cape Town by Shavina Frank, Jessica K. McGuire, Fiona Kabagenyi, Vincent Pretorius, Shazia Peer

“…We studied its response on JoRRP patients at our center. Methods: We conducted a retrospective review at Red Cross War Memorial Children’s Hospital from January 2015 to June 2022 on histologically confirmed JoRRP cases. …”
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Improving competence for practice: a realist evaluation of co-produced master-level digital sexual health promotion courses for health and welfare professionals by Kristina Areskoug Josefsson, Kristina Areskoug Josefsson, Malin Lindroth, Ane Johannesen, Gerd Hilde Lunde, Kim Jana Schultz, Daniel Masterson, Daniel Masterson

“…To improve knowledge for health and welfare professionals, co-production and shared learning are essential, as students’ learning, and professional development are facilitated by effective partnerships between universities and workplaces.MethodsUsing a theoretical framework based on the concepts co-production, work-integrated learning, digital teaching and digital didactics, an initial programme theory was created. …”
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Effectiveness of Shacklock's Neural Mobilization for Acute and Sub‐Acute Lumbar Disc Prolapsed: A Randomized Controlled Trial by Zahid Bin Sultan Nahid, Faruq Ahmed, Md Faruqul Islam, Zakia Rahman, Md Furatul Haque, Asma Arju, Md Rafiqul Islam, Golam Moula, Bibekanonda Sarker

“…The study aimed to examine the effectiveness of Shacklock's neural mobilization for acute and subacute LDP. Methods The study was a double‐blinded, randomized controlled trial. …”
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Dysphagia, nutritional status, and quality of life in patients with head and neck cancer undergoing radiotherapy alone or combined with chemotherapy: an observational study by Marina de Castro Monteiro Franco Gomes, Pedro Maciel de Vasconcellos Ferreira, Ana Clara Speziali Menegazzi Almeida, Júlia Soares Cornélio, Thiago Jardim Arruda, Arnoldo Mafra, Marcelo Henrique Silva Nunes, Rafael Borges Salera, Raquel Fabiane Nogueira, Juliana Maria Braga Sclauser, Poliana Mendes de Andrade, Luciana Priscila Marçal, Ana Paula Drummond-Lage, Bruno Almeida Rezende

“…Including CT in the RT regimen leads to a more accentuated worsening of the evaluated parameters.…”
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Trajectories of medical students’ empathy nowadays: a longitudinal study using a comprehensive framework of empathy by Valerie Carrard, Céline Bourquin, Sylvie Berney, Setareh Ranjbar, Katja Schlegel, Jacques Gaume, Pierre-Alexandre Bart, Marianne Schmid Mast, Martin Preisig, Alexandre Berney

“…Abstract Background For more than a decade, the literature has been dominated by the notion that medical students may paradoxically lose their empathy during medical school. …”
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A real-world study of the optimal cut-off value for vancomycin trough concentration associated with outcomes in children infected with drug-resistant Gram-positive bacteria by Yinghui Yan, Manli Wang, Mi Zhou, Jingxing Yang, Jingxing Yang, Zengyan Zhu, Fengjiao Wang

“…BackgroundDue to a lack of studies on the relationship between vancomycin trough concentration and clinical outcomes in pediatric patients, there is insufficient evidence to provide a unified standard for vancomycin trough concentration for children.MethodsWe retrospectively analyzed the data of drug-resistant Gram-positive bacteria isolated from human germfree samples of 66 children diagnosed as definite infectious diseases. …”
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Evaluating adherence in an active-controlled HIV pre-exposure prophylaxis trial (PrEPVacc) to inform the estimation of HIV incidence in a counterfactual placebo arm by Sheila Kansiime, Christian Holm Hansen, Henry Bern, Julie Fox, David Dunn, Eugene Ruzagira, Richard Hayes, Sheena Mc Cormack, on behalf of the PrEPVacc study team

“…In this article, we evaluate adherence to TDF/FTC in the PrEPVacc trial (NCT04066881) and consider how such adherence data could be used to estimate the effectiveness of TDF/FTC and subsequently, HIV incidence in a counterfactual placebo arm in a predominantly female population. Methods From December 2020 to March 2023 participants were recruited into the trial which included a comparison of Emtricitabine/Tenofovir Alafenamide (TAF/FTC) to TDF/FTC as PrEP over 26 weeks of follow-up, in Uganda, Tanzania, and South Africa. …”
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Targeted probiotic therapy in irritable bowel syndrome: a clinical evaluation on Clostridium butyricum CBM588 and Bifidobacterium longum W11 by Alexander Bertuccioli, Alexander Bertuccioli, Davide Sisti, Nadia Lazzerini, Chiara Maria Palazzi, Giordano Bruno Zonzini, Giordano Bruno Zonzini, Mirko Ragazzini, Annalisa Belli

“…Future studies with larger sample sizes and longer follow-up periods are recommended to confirm and expand these findings.…”
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Lifestyle and Empowerment Techniques in Survivorship of Gynaecologic Oncology (LETSGO study): a study protocol for a multicentre longitudinal interventional study using mobile heal... by Milada Cvancarova Småstuen, Ingvild Vistad, Torbjørn Wisløff, Kristina Lindemann, Lonneke V van de Poll-Franse, Mette Skorstad, Sveinung Berntsen, Ingrid Demmelmaier

“…Introduction The number of gynaecological cancer survivors is increasing and there is a need for a more sustainable model of follow-up care. Today’s follow-up model is time-consuming and patients have reported unmet needs regarding information about their cancer and strategies for managing the consequences of treatment. …”
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Microsatellite Status, Tumor Budding, CD3 and CD8 T Cell Densities in Relation to Invasiveness, Lymph Node Involvement in Colorectal Adenocarcinoma by Rebecca Noerjani Angka, Aru Wisaksosno Sudoyo, Nurjati Chairani Siregar, Wifanto Saditya Jeo, Melva Louisa, Demak Lumban Tobing

“…In this study association of TB, T cell densities and loss of MMR protein were examined to see the association with differentiation, tumor location, invasiveness and lymph node invasiveness. Methods: A retrospective cohort study was conducted using 68 CRC Formalin Fixed Paraffin Embedded samples from patients who underwent removal surgeries with the diagnosis of adenocarcinoma not otherwise specified. …”
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MCT4: a key player influencing gastric cancer metastasis and participating in the regulation of the metastatic immune microenvironment by Tao Jiang, Jingcheng Zhang, Sicheng Zhao, Mingsi Zhang, Yunhai Wei, Xiaojuan Liu, Shuo Zhang, Wei Fan, Yueying Liu, Yuanlin Lv, Guangji Zhang

“…The role of MCT4 in the occurrence and development of gastric cancer has not been clarified. Methods In this study, we comprehensively utilized single-cell sequencing and external transcriptome sequencing databases to deeply analyze the mechanism of the impact of MCT4 on gastric cancer and its microenvironment. …”
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