Men of Color Health Awareness intervention: changes in adrenocortical activity assessed using fingernail cortisol by Jerrold S. Meyer, Jeffery Markham, Lamont Scott, Luis A. Valdez, Dean E. Robinson, David R. Buchanan

“…The present paper presents an exploratory study of whether the intervention affected chronic output of the stress hormone cortisol using the novel approach of measuring cortisol accumulation in fingernail samples. Each fingernail sample was hypothesized to contain cortisol deposited over approximately a 3-month period before collection.MethodsSamples were obtained at three time points: prior to beginning of the intervention (T1; which provided an index of cortisol section during a 3-month wait-list control period); at the end of the 10-week intervention (T2); and at 12-week follow-up (T3). …”
Get full text

Length-weight relationship and condition factor of Tilapia (Coptodon zillii) from four water bodies in Kano State, Nigeria by Abdullahi M. Usman, Ibrahim O. Suleiman, Yusuf Garba, Lukman O. kareem, Usman S. Halidu, Hadiza Salihu

“…Length (L) and weight (W) of all fish sample from each location were measured using standard methods. …”
Get full text

Approaches to automation of the preanalytical phase of large-scale research in the biobank of the National Medical Research Center for Therapy and Preventive Medicine of the Minist... by M. S. Pokrovskaya, A. L. Borisova, V. A. Kondratskaya, I. A. Efimova, A. I. Ershova, O. M. Drapkina

“…To create and validate an algorithm for automatic aliquoting of serum and plasma samples for biobanking as part of a large-scale study.Material and methods. …”
Get full text

Genomic signatures in plasma circulating tumor DNA reveal treatment response and prognostic insights in mantel cell lymphoma by Zhou Ouyang, Ruolan Zeng, Song Wang, Xiaoying Wu, Yajun Li, Yizi He, Caiqin Wang, Chen Xia, Qiuxiang Ou, Hua Bao, Wei Yang, Ling Xiao, Hui Zhou

“…The applicability of circulating tumor DNA (ctDNA) for predicting treatment response and prognosis in MCL remains underexplored. Methods This study included 34 MCL patients receiving first-line chemoimmunotherapy. …”
Get full text

Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis. by William D Thompson, Jessica Tyrrell, Maria-Carolina Borges, Robin N Beaumont, Bridget A Knight, Andrew R Wood, Susan M Ring, Andrew T Hattersley, Rachel M Freathy, Debbie A Lawlor

“…Our aim was to combine genetic and RCT data to estimate causal effects of these two maternal traits on offspring birth weight.<h4>Methods and findings</h4>We performed two-sample mendelian randomisation (MR) using genetic instrumental variables associated with 25(OH)D and calcium that had been identified in genome-wide association studies (GWAS; sample 1; N = 122,123 for 25[OH]D and N = 61,275 for calcium). …”
Get full text

An Audit of Patient Characteristics, Contributing Factors, and Outcomes of Patients Leaving against Medical Advice at Sheikh Khalifa Medical City Abu Dhabi by Shamma Salem Alhajeri, Ibrahim Atfah, Ali Bin Yahya, Salama Matar Al Neyadi, Fatema Salem Al Ameri, Nasser Ahmed, Ismail Al Ramahi, Kenneth Charles Dittrich, Hasan Qayyum

“…Objectives: The primary aim of this audit was to evaluate the demographic and socio-economic characteristics of patients who opt for LAMA, identify contributing factors in patients who opt for LAMA, and benchmark our current practice against a SEHA policy guideline (Policy no. C-MD-GEN-01-024). Methods: We analyzed the electronic health records at Sheikh Khalifa Medical City, Abu Dhabi, for ED patients who signed LAMA between 2018 and 2023, selecting a convenience sample of 120 patients. …”
Get full text

Multi-omics analysis reveals the physiological and molecular response to cold stress in different spring wheat cultivars at the booting stage by Miao Liu, Miao Liu, Xiaoli Wu, Xiaoli Wu, Ming Li, Shizhao Li, Tao Xiong, Chaosu Li, Chaosu Li, Yonglu Tang, Yonglu Tang

“…Transcriptome analysis identified 7,362 and 5,328 differentially expressed genes (DEGs) between control and cold-treated CM104 and CM42 spike samples, respectively. More DEGs, such as transcription factors, late embryogenesis abundant protein and hormone signalling transduction involved in the key regulatory pathways associated with cold tolerance were expressed in CM104. …”
Get full text

Linking peri-implantitis to microbiome changes in affected implants, healthy implants, and saliva: a cross-sectional pilot study by Lucinda J. Bessa, Conceição Egas, Conceição Egas, Conceição Egas, Carolina Pires, Luís Proença, Paulo Mascarenhas, Ricardo J. Pais, Ricardo J. Pais, Helena Barroso, Vanessa Machado, João Botelho, Gil Alcoforado, José João Mendes, Ricardo Alves

“…IntroductionThe rising use of dental implants is accompanied by an expected increase in peri-implant diseases, particularly peri-implantitis (PI), which poses a significant threat to implant success and necessitates a thorough understanding of its pathogenesis for effective management.MethodsTo gain deeper insights into the role and impact of the peri-implant microbiome in the pathogenesis and progression of PI, we analyzed 100 samples of saliva and subgingival biofilm from 40 participants with healthy implants (HI group) or with co-occurrence of diagnosed PI-affected implants and healthy implants (PI group) using shotgun metagenomic sequencing. …”
Get full text

Early plant disease diagnosis through handheld UV–Vis transmittance spectrometer with DD-SIMCA one-class classification and MCR-ALS bilinear decomposition by Mafalda Reis-Pereira, Sarmento J. Mazivila, Fernando Tavares, Filipe Neves dos Santos, Mário Cunha

“…DD-SIMCA results indicate that non-target class of samples with higher proximity to the acceptance boundary suggested that they were at earlier stages of infection when compared to more distant ones, presenting lower full distance values. …”
Get full text

Synchrotron-based 3D X-ray computed tomography reveals root system architecture: Plastic responses to phosphorus placement by Frederik J.T. van der Bom, Philipp D. Lösel, Andrew M. Kingston, Zhe H. Weng, Nelly S. Raymond, Anton Maksimenko, Daniel Hausermann, Michael J. Bell, Casey L. Doolette, Enzo Lombi, Peter M. Kopittke

“…To optimize scanning quality, we tested the use of an inverse ‘mask’ in front of the soil cores to achieve a more uniform attenuation along the sample, thereby avoiding saturation of the detector along the thinnest parts of the soil cores. …”
Get full text

Snapshot of knowledge and stigma toward mental health disorders and treatment in Spain by Andrea Varaona, Rosa M. Molina-Ruiz, Rosa M. Molina-Ruiz, Luis Gutiérrez-Rojas, Luis Gutiérrez-Rojas, Maria Perez-Páramo, Guillermo Lahera, Guillermo Lahera, Guillermo Lahera, Carolina Donat-Vargas, Carolina Donat-Vargas, Carolina Donat-Vargas, Miguel Angel Alvarez-Mon, Miguel Angel Alvarez-Mon, Miguel Angel Alvarez-Mon, Miguel Angel Alvarez-Mon

“…Psychological and pharmacological treatment are considered to be effective and helpful by more than 70% of the sample. More than 60% of the participants highlighted that suicide needs to be addressed appropriately in the media.ConclusionThese findings suggest a significant shift in how Spanish society views mental disorders, marking progress over decades of discrimination. …”
Get full text

The SDSS-V Local Volume Mapper: Data Analysis Pipeline by Sebastián F. Sánchez, Alfredo Mejía-Narváez, Oleg V. Egorov, Kathryn Kreckel, Niv Drory, Guillermo A. Blanc, J. Eduardo Méndez-Delgado, Jorge K. Barrera-Ballesteros, Hector Ibarra-Medel, Dmitry Bizyaev, Pablo García, Aida Wofford, Alejandra Z. Lugo-Aranda

“…To assess the accuracy of our results, we compare them with both idealized and more realistic simulations, highlighting the limitations of our methods. …”
Get full text

Acoustic Enhancement Performance of Hierarchical ZSM-5 Zeolites with Different Si/Al Ratios by Mingbo Guo, Yijun Wang, Lei Zhang, Junran Lu, Chang Gong, Wanning Zhang, Yuxi Fang, Xinyuan Zhu, Shunai Che

“…In this work, hierarchically structured ZSM-5 zeolites with abundant mesopores were synthesized via the traditional hydrothermal method by adjusting the SiO₂/Al₂O₃ ratios (SAR), and their pore structures and morphologies were systematically investigated. …”
Get full text

Brain functional imaging contributions in osteoarthritis-related pain: A viewpoint by Camille Fauchon, Marie Binvignat, Francis Berenbaum, Philip G. Conaghan, Roland Peyron, Jérémie Sellam, Françoise Alliot-Launois, Nadine Attal, Francis Berenbaum, Marie Binvignat, Philip Conaghan, Alice Courties, Niels Eijkelkamp, Camille Fauchon, Rinie Geenen, Ida K. Haugen, Yves Henrotin, Kalle Kisand, Margreet Kloppenburg, Eva Kosek, Liisa Kuhi, Sylvain Mathieu, Céline Mathy, Ali Mobasheri, Stanislas Moumbe Talla, Patrick Omoumi, Serge Perrot, Roland Peyron, Simo Saarakkala, Alain Saraux, Hans-Georg Schaible, Jérémie Sellam

“…This viewpoint aims to summarize the importance of the brain in OA pain. Method: A European working group on pain in osteoarthritis GO-PAIN (Going Inside Osteoarthritis-related Pain Phenotyping) has been created to work on a global assessment of the OA-related pain. …”
Get full text

Clinical characteristics and efficiency of antidepressant therapy of mood disorders with comorbid alcohol use disorder by O. V. Roshchina, A. I. Rozin, E. D. Schastnyy, N. A. Bokhan

“…In the study, we applied clinical-psychopathologic, clinical-dynamic, and statistical methods with Pearson’s χ2 test, Mann – Whitney U-test (for comparison of independent samples), Kruskal – Wallis test (for more than two independent samples), and Wilcoxon test (for comparison of dependent samples). …”
Get full text

Sheep challenged with sheep-derived type II Mycobacterium avium subsp. paratuberculosis: the first experimental model of paratuberculosis in China by Meng-Yuan Li, Wei-Kang Meng, Wei Ma, Yu-Lin Ding, Bo Yang, Wei-Hong Zhao, Hasi Bayaer, Alateng Bagen, Rui-Bin Chen, Siqin Tunala, Rong Zhang, Chen-Guang Du, Li Zhao, Yong-Hong Liu

“…Currently, early PTB diagnosis requires a combination of multiple sample types and detection methods.…”
Get full text

Adenosine A1 Receptor Deficiency Aggravates Extracellular Matrix Accumulation in Diabetic Nephropathy through Disturbance of Peritubular Microenvironment by Dongli Tian, Jiaying Li, Linfeng Zou, Min Lin, Xiaoxiao Shi, Yuting Hu, Jiaxin Lang, Lubin Xu, Wenling Ye, Xuemei Li, Limeng Chen

“…In this study, we aimed to explore the role of A1AR in the fibrosis progression of DN. Methods. We collected DN patients’ samples and established a streptozotocin-induced diabetes model in wild-type (WT) and A1AR-deficient (A1AR-/-) mice. …”
Get full text

Emerging malaria in Indonesia: An overview of Plasmodium knowlesi infections by Nisa Fauziah, Karomahul Malaya Jati, Fedri Ruluwedrata Rinawan, Naufal Fakhri Nugraha, Bachti Alisjahbana, Jontari Hutagalung

“…This study aimed to provide an overview of malaria caused by P. knowlesi in Indonesia. Methods: This study utilized secondary data from the Indonesian National Referral Malaria Laboratory from 2011 to 2020 for the analysis. …”
Get full text

Improving outcomes for people with autism spectrum disorders by reducing mental health problems: the IAMHealth research programme including one RCT by Emily Simonoff, Gillian Baird, Bryony Beresford, Tony Charman, Martin Knapp, Andrew Pickles, Carol Povey, Tom Purser, Paramala Santosh, Vicky Slonims, Stephen Scott

“…The ACB was subjected to stringent psychometric evaluation, including replication of the structure in a second sample, and was found to be robust. Work package 2: biographies Methods Using an existing research cohort, we purposively sampled autistic young adults with previous experience of a range of MHBP. …”
Get full text

Immunological landscape of children with Mycoplasma pneumoniae pneumonia in the post-COVID-19 era reveals distinctive severity indicators by Ran Jia, Haiyan Guo, Aizhen Lu, Caiyan Zhang, Yuanyuan Qi, Dingmei Wang, Wen He, Qing Wang, Zimei Cheng, Yajing Gao, Guoping Lu, Libo Wang, Xiaowen Zhai, Jin Xu, Xiaobo Zhang, Yi Wang, Yufeng Zhou

“…Their blood samples were analyzed using flow cytometry, multi-cytokine assays, and antibody detection methods. …”
Get full text