Effect of Gamification on Improved Adherence to Inhaled Medications in Chronic Obstructive Pulmonary Disease: Randomized Controlled Trial by Xiting Huang, Zhili Jiang, Yifan Dai, Yang Liu, Ziying Dai, Jing Wang, Liping Chen, Zhiqian Wang, Wenxiao Wu, Lihua Huang

“…ObjectiveThis study aimed to explore the effectiveness of an inhaled medication education program (Inhaling-Health website) based on the Fogg Behavior Model and gamification design on inhaled medication compliance and other health-related outcomes in patients with COPD. MethodsIn a randomized, 2-arm, concurrent parallel design, we enrolled 102 patients with COPD from respiratory medicine clinics at 2 hospitals in Zhejiang Province, China, between April and May 2023. …”
Get full text

COVID-19 vaccination hesitancy and associated factors among the business community in Lira City, Uganda: a cross-sectional research by Eustes Kigongo, Everlyne Achan, Bosco Opio, Anne Ruth Akello, Marvin Musinguzi, Raymond Tumwesigye, Amir Kabunga, Sean Steven Puleh

“…This study aimed to assess COVID-19 vaccination hesitancy and associated factors among the business community in Lira City, Uganda. Methods: Descriptive cross-sectional design was conducted among the business community from Lira City in Northern Uganda. …”
Get full text

Serum C-reactive protein and nutritional parameters in hemodialysis patients by Dragović Tamara, Mijušković Mirjana, Terzić Brankica, Ristić-Medić Danijela, Hajduković Zoran, Rađen Slavica

“…The high serum CRP levels (more than 3 mg/L) was found in 65.3% of patients. …”
Get full text

Effect of intermediate airway management on ventilation parameters in simulated paediatric out-of-hospital cardiac arrest: a multicentre randomised crossover trial by Loric Stuby, Laurent Bourgeois, Jean-Marie Tinembart, Elisa Mühlemann, David Thurre, Johan N. Siebert, Laurent Suppan

“…Intermediate airway management delivered more ventilations, but bag-valve-mask enabled quicker ventilation initiation and more ventilations within the target volume. …”
Get full text

Chromosomal abnormalities in couples with recurrent pregnancy loss: a 16-year cross-sectional study of 4030 cases from Turkey by Sabri Aynaci, Sinem Kocagil, Efsun Tosumoglu, Ezgi Susam, Betul Kilic, Ebru Erzurumluoglu Gokalp, Oguz Cilingir, Beyhan Durak Aras, Basar Tekin, Sevilhan Artan

“…MAIN OUTCOME MEASURES: Chromosomal abnormalities in patients diagnosed with primary recurrent pregnancy loss and genetic testing results of spontaneously achieved pregnancies in 16 patients with a balanced chromosomal rearrangement. SAMPLE SIZE: 4030 individuals (2015 couples) RESULTS: Majority of couples had a history of two spontaneous miscarriages (59.4%), followed by couples with 3 miscarriages (28.1%), 4 miscarriages (7.5%), and 5 or more miscarriages (4.91%). …”
Get full text

Evaluating the Clinical Benefit of Carbapenem-Resistant Enterobacteriaceae Screening in a Tertiary Care Center in Saudi Arabia by Mahmoud E, Alhameed AF, Almukhtar A, Desai S

“…The researchers found that patients who tested positive for CRE were more likely to develop serious infections, have longer hospital stays, and face a higher risk of death compared to those who tested negative. …”
Get full text

The Incidence and Risk Factors of Falls During Pregnancy by Paula Drabiščáková, Júlia Hederlingová, Petra Oťapková, Natália Dominová, Miroslava Jurčišinová, Zuzana Chválna, Jozef Záhumenský

“…The secondary objective was to identify the risk factors for falls during pregnancy. Methods: 165 healthy singleton pregnant women were included in the study. …”
Get full text

Abstract 147: Utilization and Application of Transcranial Doppler Emboli Monitoring for Infective Endocarditis by Giana Dawod, Paulina Diaz, Nicholas Janocko, Alexander E. Merkler

“…While our observational study was limited by our sample size, both of our IE patients who had positive TCD with HITS studies developed more severe CV complications, and aggressive care was sought out more urgently to further minimize complications. …”
Get full text

Integration of single-cell sequencing and drug sensitivity profiling reveals an 11-gene prognostic model for liver cancer by Qunfang Zhou, Jingqiang Wu, Jiaxin Bei, Zixuan Zhai, Xiuzhen Chen, Wei Liang, Jing Meng, Mingyu Liu

“…Mutation analysis showed more TP53 mutations in the high-risk group and more CTNNB1 mutations in the low-risk group. …”
Get full text

A család ereje: A házasságban élés és a nagycsaládos lét kapcsolata a jóllét különböző mutatóival by Andrea FERENCZI, Zsuzsanna KÖVI, Veronika MÉSZÁROS

“…The sample included 220 married individuals raising three or more children, while 363 participants reported regularly practising their religion. …”
Get full text

Epigenetic age and fertility timeline: testing an epigenetic clock to forecast in vitro fertilization success rate by Davide Marinello, Marco Reschini, Giorgia Di Stefano, Giorgia Carullo, Maíra Casalechi, Letizia Tarantini, Benedetta Albetti, Valentina Bollati, Paola Viganò, Edgardo Somigliana, Letizia Li Piani

“…We investigated the potential role of epigenetic clocks in predicting IVF success. Methods This prospective observational study involved 379 women of reproductive age who underwent IVF treatment. …”
Get full text

Self‐stigma among people with epilepsy: Comparison between Germany and Japan by Izumi Kuramochi, Takayuki Iwayama, Hiroaki Okajima, Satsuki Watanabe, Koji Matsuo, Haruo Yoshimasu, Christian G. Bien, Christian Brandt, Anne Hagemann

“…It also explored cultural differences influencing these experiences. Methods Participants were recruited from the Bethel Epilepsy Center in Germany and the Comprehensive Epilepsy Centers at Saitama Medical University in Japan. …”
Get full text

Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC by Xiyu Song, Xiyu Song, Xiyu Song, Jianhua Jiao, Jianhua Jiao, Jiayang Qin, Wei Zhang, Weijun Qin, Weijun Qin, Shuaijun Ma, Shuaijun Ma

“…IntroductionThe role of mast cells (MCs) in clear cell renal carcinoma (ccRCC) is unclear, and comprehensive single-cell studies of ccRCC MCs have not yet been performed.MethodsTo investigate the heterogeneity and effects of MCs in ccRCC, we studied single-cell transcriptomes from four ccRCC patients, integrating both single-cell sequencing and bulk tissue sequencing data from online sequencing databases, followed by validation via spatial transcriptomics and multiplex immunohistochemistry (mIHC).ResultsWe identified four MC signature genes (TPSB2, TPSAB1, CPA3, and HPGDS). …”
Get full text

Disrupted Vaginal Microbiota and Increased HPV Infection Risk Among Non-Vaccinated Women: Findings from a Prospective Cohort Study in Kazakhstan by Kuralay Kongrtay, Kuat Kassymbek, Gulzhanat Aimagambetova, Nazira Kamzayeva, Sanimkul Makhambetova, Makhabbat Galym, Zhanar Abdiyeva, Milan Terzic, Kadisha Nurgaliyeva, Talshyn Ukybassova

“…<b>Results:</b> HPV-positive women were significantly younger and more likely to be single compared to HPV-negative participants. …”
Get full text

Host and bacterial urine proteomics might predict treatment outcomes for immunotherapy in advanced non-small cell lung cancer patients by David Dora, Peter Revisnyei, Peter Revisnyei, Alija Pasic, Gabriella Galffy, Edit Dulka, Anna Mihucz, Brigitta Roskó, Sara Szincsak, Anton Iliuk, Glen J. Weiss, Zoltan Lohinai, Zoltan Lohinai

“…IntroductionUrine samples are non-invasive approaches to study potential circulating biomarkers from the host organism. …”
Get full text

Cytostatic effect of extracts from <i>Heracleum Sosnowskyi</i> by R. I. Lukashou, N. S. Gurina, V. A. Tsiarletskaya, A. V. Laurouski, T. M. Doroshenko, A. S. Portyanko, A. V. Klemper, M. N. Povydysh

“…To analyze the cytostatic effect of extracts from the herb, inflorescences and roots of Heracleum Sosnowskyi on tumor cell cultures in vitro.Materials and methods. The object of the study was air-dried herbs and inflorescences harvested during the flowering period and roots harvested during the dying off period of the above-ground part of Heracleum Sosnowskyi. …”
Get full text

Clinical and biochemical characteristics of patients with acromegaly and normal or increased prolactin levels by Yuliya A. Kukushkina, Irena A. Ilovayskaya

“…Aim: To identify hallmarks of clinical and biochemical parameters in patients with acromegaly and normal or increased prolactin level. Methods: We performed a single center, single sample retrospective, observational cohort uncontrolled non-interventional study in 306 patients (70 men and 236 women) with acromegaly examined from July 2021 to June 2024, 50 of them with a pituitary microadenomas and 256 with macroadenomas. …”
Get full text

Predictive Modeling of Acute Respiratory Distress Syndrome Using Machine Learning: Systematic Review and Meta-Analysis by Jinxi Yang, Siyao Zeng, Shanpeng Cui, Junbo Zheng, Hongliang Wang

“…MethodsWe performed a search across 6 electronic databases for studies developing ML predictive models for ARDS, with a cutoff date of December 29, 2024. …”
Get full text

Effects of ketogenic diets on polycystic ovary syndrome: a systematic review and meta-analysis by Rossella Cannarella, Michele Rubulotta, Alessia Leonardi, Andrea Crafa, Antonio Calvo, Federica Barbagallo, Sandro La Vignera, Aldo E. Calogero

“…Further studies with larger sample sizes and more robust study designs are needed to confirm these findings.…”
Get full text

Effects of Plant-Origin Superoxide Dismutase Supplementation on Selected Parameters of Inflammation and White Blood Cell Count in Athletes by Olina Dudašova Petrovičova, Ivan Stanković, Brižita Đorđević, Neda Milinković, Violeta Dopsaj, Milivoj Dopsaj

“…The aim of this study was to investigate the effects of antioxidant supplementation on parameters of immunity and inflammation in athletes. Methods: The study included 14 elite rowers (group 1) and 10 recreational athletes (group 2). …”
Get full text