Epigenetic Study of Cohort of Monozygotic Twins With Hypertrophic Cardiomyopathy Due to MYBPC3 (Cardiac Myosin‐Binding Protein C) by Alfonso Peñarroya, Rebeca Lorca, José Julián Rodríguez Reguero, Juan Gómez, Pablo Avanzas, Juan Ramon Tejedor, Agustín F. Fernandez, Mario F. Fraga

“…In this study we aimed to establish a possible correlation between the peripheral blood DNA methylation patterns and left ventricular hypertrophy severity in patients with hypertrophic cardiomyopathy, evaluating the potential impact of lifestyle variables and providing a biological context to the observed changes. Methods and Results Methylation data were obtained from peripheral blood samples (Infinium MethylationEPIC BeadChip arrays). …”
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Continuous local anaesthetic wound infusion in infants undergoing thoracic or abdominal surgery: A systematic review by Jeewan Jyoti, Eva Sloukova, Kaye Spence, Annabel Webb, Albert Shun, Himanshu Popat

“…Methods: Cochrane Central Register of Controlled Trials, Medline, Embase and CINAHL were searched from database inception to August 2022. …”
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Changes in LEND trainees’ understanding and application of diversity, equity, inclusion, and justice principles by Allison P. Fisher, Lisa M. Gies, Stephanie Weber, Stephanie Weber, Tanya Froehlich, Tanya Froehlich, Simon Abimosleh, Neeraja Ravindran, Jennifer Smith, Jennifer Smith

“…Changes in trainees’ responses were examined using paired-samples t-tests.ResultsThirty-six (78%) participants identified as White, 7 (15%) as Black, 2 (4%) as Asian, and 2 (4%) as more than one race. …”
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Occurrence of Endoparasites in Creole Goats Under an Extensive Production System on the Southern Coast of Peru by Emmanuel Sessarego, Jhony Soca-Jorge, Jose Teran, María Dávalos-Almeyda, Justo Valdivia-Zevallos, Jose Ruiz, Juancarlos Cruz, Danny Julio Cruz

“…Data were analyzed using logistic regression models and adjusted through bootstrapping and stepwise selection methods, with locality, feeding type, age, and body condition as predictive variables. …”
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Predictors of Success in Horizontal Strabismus Surgery: Insights from a Prospective Study by Aurellia Valmai Tjujitno, Reni Prastyani, Joni Susanto, Rozalina Loebis, Luki Indriaswati, Lely Retno Wulandari

“…This study explored the surgical outcomes of horizontal strabismus correction in patients, aiming to provide insights into the factors influencing success. Methods: A prospective study was conducted with 17 patients (n=17) who underwent surgery at Dr. …”
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An assessment of the role of buttress roots in the carbon stocks of tropical forests by Xu Wang, Xu Wang, Brian Njoroge Mwangi, Brian Njoroge Mwangi, Guangyi Zhou, Guangyi Zhou, Mengmeng Yang, Mengmeng Yang, Yuelin Li, Yuelin Li

“…This study aims to address this knowledge gap.MethodsThis study collected soil samples and made physical measurements of buttressed, control, and non-buttressed trees in a tropical forest from 2020 to 2022. …”
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mRNA expression of chemosensitivity genes as a predictor of response to neoadjuvant chemotherapy in non-small cell lung cancer by M. M. Tsyganov, I. V. Deryusheva, E. O. Rodionov, L. A. Efteev, S. V. Miller, M. K. Ibragimova, E. E. Perminova, O. V. Cheremisina, I. G. Frolova, S. A. Tuzikov, N. V. Litviakov

“…Therefore, the search for new predictive factors and markers that could precisely predict the NAC response and be relevant to the choice of the adequate treatment policy is of utmost importance. the purpose of the study was to analyze the relationship between the expression levels of chemosensitivity genes and NAC response in patients with non-small cell lung cancer. material and methods. The study included 30 patients with stage IIAIIIB NSCLC. …”
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Adolescent developmental assets and longitudinal weight status and psychosocial health outcomes: Exploratory analysis from a youth cohort study in Taiwan by Meng-Che Tsai, Jennifer M.T. Ng, Yi-Fang Yu, Carol Strong, Yi-Ping Hsieh, Yi-Ching Lin, Chung-Ying Lin

“…This study aims to extend the current knowledge regarding the effects of positive youth development on weight status and psychosocial health outcomes in young adulthood using a large representative longitudinal sample. Methods: Data were retrieved from the Taiwan Youth Project that comprised a longitudinal cohort of adolescents (N = 2688) surveyed at grades 7, 8, 9, and 12, and at age 22. …”
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Propagation Characteristics of Multi-Cluster Hydraulic Fracturing in Shale Reservoirs with Natural Fractures by Lianzhi Yang, Xinyue Wang, Tong Niu

“…Hydraulic fracturing of gas and oil reservoirs is the primary stimulation method for enhancing production in the field of petroleum engineering. …”
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Construction and Application of Monitoring System for Green Tarpaulin Cover Net in Mega Cities by Yang SUN, Dawei GAO, Haoye JIANG, Wanguang DU

“…There is still a gap in research in this field both domestically and internationally, and there is an urgent need for a scientific and systematic monitoring system to support the effective promotion of the special work of “net uncovering for greening”.MethodsTaking the special work of “net uncovering for greening” in Beijing as an example, this research combines the technical means of remote sensing interpretation and deep learning with the U-Net model to train the samples of tarpaulin cover. …”
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Genomic characteristics and prognostic correlations in Chinese multiple myeloma patients by Xi Chen, Tianchen Luo, Wenhui Zhang, Sheng Wang, Mengxuan Zhu, Haiyan He, Jin Liu, Jing Lu, Wanting Qiang, Yanchun Jia, Nan Hou, Xuenan Zhao, Shan Zhang, Jing Li, Juan Du

“…The heterogeneity in Chinese MM populations remains underexplored. Methods We conducted whole-exome sequencing (WES) on 241 tumor samples, complemented by RNA sequencing (RNA-seq) on 131 samples from 212 Chinese MM patients. …”
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Xylazine prevalence and concentration in the Los Angeles fentanyl market, 2023–2025 by Joseph Friedman, Caitlin A. Molina, Adam J. Koncsol, Ruby Romero, Morgan E. Godvin, Elham Jalayer, Spider Davila, Oscar Arellano, Amanda Cowan, Brian Hurley, Chelsea L. Shover

“…Emerging drug checking approaches can provide information about the concentration and prevalence of xylazine in illicit fentanyl. Methods: Fentanyl samples from a community-based drug checking program in Los Angeles, California were assessed using direct analysis in real time mass spectrometry (DART-MS). …”
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Risk and recovery among high school athletes who sustained at least one sports-related concussion by Adam R Kinney, Dustin Anderson, Kelly A Stearns-Yoder, Lisa A Brenner, Jeri E Forster

“…Aim: Evidence of factors explaining sports-related concussion (SRC) risk and recovery among high school athletes remains inconclusive. Materials & methods: Prospective study of a real-world sample of high school athletes (n = 77) who sustained ≤1 SRC. …”
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Application of high-throughput sequencing in citrus virus identification and analysis of population diversity by LI Xiang, YANG Jin, HUANG Aijun, ZHOU Jun, YI Long

“…The above methods are well-suited for known viruses and can be combined with multiple methods for detection and identification. …”
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Organic petrography and geochemistry of the Pabdeh Formation in Khaviz and Mansourabad anticlines, SW Iran by Marziyeh Khazami, Majid Alipour

“…Abstract This paper presents the results from organic geochemical evaluation of the Paleocene–Eocene Pabdeh Formation in the Khaviz Anticline and Mansourabad Oilfield by a combination of Rock-Eval pyrolysis method and organic petrographic techniques. A total of 24 cutting samples, collected from these anticlines, were subjected to Rock-Eval pyrolysis, and 12 samples were subsequently selected for complementary petrographic inspections. …”
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Older Fallers’ Comprehensive Neuromuscular and Kinematic Alterations in Reactive Balance Control: Indicators of Balance Decline or Compensation? A Pilot Study by Ringo Tang-Long Zhu, Timmi Tim Mei Hung, Freddy Man Hin Lam, Jun-Zhe Li, Yu-Yan Luo, Jingting Sun, Shujun Wang, Christina Zong-Hao Ma

“…Previous studies have compared postural sways or stepping strategies between older adults with and without fall histories to identify factors associated with falls. However, more in-depth neuromuscular/kinematic mechanisms have remained unclear. …”
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Addition of PARP1-inhibition enhances chemoradiotherapy and thermoradiotherapy when treating cervical cancer in an in vivo mouse model by Marloes IJff, Xionge Mei, Enzo M. Scutigliani, Hans M. Rodermond, Gregor G. W. van Bochove, Przemek M. Krawczyk, Nicolaas A. P. Franken, Lukas J. A. Stalpers, Johannes Crezee, Arlene L. Oei

“…The aim of our present study was to test efficacy of different combinations of treatment modalities radiotherapy, cisplatin, hyperthermia and PARP1-inhibitors using in vitro tumor models, ex vivo treated patient samples and in vivo tumor models.Materials and Methods: In vitro clonogenic survival curves (0–6 Gy) show that PARP1-i (4–5 M Olaparib) enhances both chemoradiotherapy (0.3–0.5 µM cisplatin) and thermoradiotherapy (42 °C for 1 h) in SiHa, CaSki and HeLa cells. …”
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Prognostic significance of perioperative circulating CD56bright NK cell and recovery of NK cell activity in patients with colorectal cancer undergoing radical surgery by Jeng-Fu You, Cheng-Chi Lee, Yun-Shien Lee, Yih-Jong Chern, Chun-Kai Liao, Hung-Chih Hsu

“…This study explores the relationship between NK cell/NKA and clinicopathological factors during the perioperative period in patients with CRC. Methods: We prospectively enrolled 45 patients with CRC. …”
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ICalled-DIY Device for Hands-On and Low-Cost Adapted Emergency Call Learning: A Simulation Study by Luis Castro-Alonso, Sheila Vázquez-Álvarez, Santiago Martínez-Isasi, María Fernández-Méndez, Luz Rey-Fernández, María García-Martínez, Adriana Seijas-Vijande, Roberto Barcala-Furelos, Martín Otero-Agra

“…<b>Objective</b>: To assess the efficacy of a low-cost, Do-It-Yourself training material for emergency call simulation training, compared to a more traditional approach. <b>Methods</b>: A quasi-experimental design without pre-test was used. …”
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Endodontic Tendencies in a Very-Low-Income Population Area of Northeastern Brazil by Maria Tereza Pedrosa Albuquerque, Joice Velames Silva, David Junio Oliveira Poppe, Crislaine Santana Santos, Tainá Pires Santos, Eliseu Aldrigh Münchow, Juliana Yuri Nagata

“…To gather information regarding endodontic treatment protocols and continuing education attendance of dentists in some cities located in Northeastern Brazil (Sergipe and Bahia States), a region that comprises a very-low-income population. Methods. A questionnaire containing different questions (e.g., routine treatment protocols, the use of new technologies, time required to conclude the treatment, and attendance in an endodontic continuing education) was distributed to 250 dentists. …”
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