Protocol for a realist evaluation of Recovery College dementia courses: understanding coproduction through ethnography by Geoff Wong, Bonnie Teague, Chris Fox, Esme Moniz-Cook, Claire Duddy, Emma Wolverson, Fiona Poland, Linda Birt, Corinna Hackmann, Melanie Handley, Rachael Litherland, Juniper West, Ruth Mills, Kathryn Sams

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SPIRIT 2025 statement: Updated guideline for protocols of randomised trials by An-Wen Chan, Isabelle Boutron, Sally Hopewell, David Moher, Kenneth F. Schulz, Gary S. Collins, Ruth Tunn, Rakesh Aggarwal, Michael Berkwits, Jesse A. Berlin, Nita Bhandari, Nancy J. Butcher, Marion K. Campbell, Runcie C. W. Chidebe, Diana R. Elbourne, Andrew J. Farmer, Dean A. Fergusson, Robert M. Golub, Steven N. Goodman, Tammy C. Hoffmann, John P. A. Ioannidis, Brennan C. Kahan, Rachel L. Knowles, Sarah E. Lamb, Steff Lewis, Elizabeth Loder, Martin Offringa, Philippe Ravaud, Dawn P. Richards, Frank W. Rockhold, David L. Schriger, Nandi L. Siegfried, Sophie Staniszewska, Rod S. Taylor, Lehana Thabane, David J. Torgerson, Sunita Vohra, Ian R. White, Asbjørn Hróbjartsson

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SPIRIT 2025 statement: Updated guideline for protocols of randomised trials. by An-Wen Chan, Isabelle Boutron, Sally Hopewell, David Moher, Kenneth F Schulz, Gary S Collins, Ruth Tunn, Rakesh Aggarwal, Michael Berkwits, Jesse A Berlin, Nita Bhandari, Nancy J Butcher, Marion K Campbell, Runcie C W Chidebe, Diana R Elbourne, Andrew J Farmer, Dean A Fergusson, Robert M Golub, Steven N Goodman, Tammy C Hoffmann, John P A Ioannidis, Brennan C Kahan, Rachel L Knowles, Sarah E Lamb, Steff Lewis, Elizabeth Loder, Martin Offringa, Philippe Ravaud, Dawn P Richards, Frank W Rockhold, David L Schriger, Nandi L Siegfried, Sophie Staniszewska, Rod S Taylor, Lehana Thabane, David J Torgerson, Sunita Vohra, Ian R White, Asbjørn Hróbjartsson

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Risk of bias and confounding of observational studies of Zika virus infection: A scoping review of research protocols. by Ludovic Reveiz, Michelle M Haby, Ruth Martínez-Vega, Carlos E Pinzón-Flores, Vanessa Elias, Emma Smith, Mariona Pinart, Nathalie Broutet, Francisco Becerra-Posada, Sylvain Aldighieri, Maria D Van Kerkhove

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Informing family physician payment reform in Canada: protocol for a cross-provincial, multimethod study by Agnes Grudniewicz, Kimberlyn McGrail, Alan Katz, M Ruth Lavergne, David Rudoler, Lindsay Hedden, Maria Mathews, Rita McCracken, Erin C Strumpf, Nichole Austin, Gayle Halas, Sarah Spencer, Ted McDonald, Hugh Shiplett, Rachel Thelen

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Scope of practice of primary care nurses: a protocol for an umbrella review of international literature by Kris Aubrey-Bassler, Marie-Ève Poitras, Shabnam Asghari, Michelle Swab, Lindsay Hedden, Maria Mathews, Ruth Martin-Misener, Elizabeth J Halcomb, Julia Lukewich, Leslie Meredith, Dana Ryan, Suzanne Braithwaite, Danielle Macdonald, Kathleen Leslie, Anaelle Morin, Monica McGraw, Patrick Chiu, Émilie Dufour, Sophia Myles, Annie Rioux-Dubois, Deanne Curnew, Jen Calver, Jill Bruneau

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Protocol for the Tallaght University Hospital Institute for Memory and Cognition-Biobank for Research in Ageing and Neurodegeneration by Eimear Connolly, Shane Lyons, Cliona O’Farrelly, Graham Knight, Antoinette O’Connor, Adam H Dyer, Sean P Kennelly, Emily Killeen, Christine Gaffney, Helena Dolphin, Laura Morrison, Gavin Sedgwick, Aoife McFeely, Conal Gallagher, Naomi Davey, Conor Young, Ruth Ennis, Cathy McHale, Jasmine Joseph, Emmet Kelly, Nollaig M Bourke, Aoife Fallon, Sean O’Dowd

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Assessing Major Organ Dysfunction in Children With Sickle Cell Disease: Protocol for a Cross‐Sectional Study by Vivian Paintsil, Sandra Kwarteng Owusu, Samuel Blay Nguah, Serwah Bonsu Asafo‐Agyei, Augustina Badu‐Peprah, Lawrence Osei‐Tutu, Christiana Adu‐Takyi, Tony Boakye, Bernice Eklu, Eugenia Osei, Ruth Owusu‐Antwi, George Asafu‐Adjaye Frimpong, Evans Xorse Amuzu, Daniel Ansong

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Effect of psychosocial work factors on the risk of depression: a protocol of a systematic review and meta-analysis of prospective studies by Mahée Gilbert-Ouimet, Chantal Brisson, Xavier Trudel, Michel Vézina, Lynne Moore, Caroline S Duchaine, Karine Aubé, Ana Paula Bruno Pena Gralle, Ruth Ndjaboue, Victoria K Massamba, Alain Lesage, Danielle Laurin

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Effectiveness and Cost-Effectiveness of a Mobile Psychoeducation Program (OkeyMind) for Social Anxiety Symptoms Among Youths: Protocol for a Randomized Controlled Trial by Yi-Zhou Wang, De-Hui Ruth Zhou, Siu-Man Ng, Bei-Bei Wang, Yu-Ya Feng, Xue Weng

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Protocol for a case–control diagnostic accuracy study to develop diagnostic criteria for psoriasis in children (DIPSOC study): a multicentre study recruiting in UK paediatric derma... by Kim Suzanne Thomas, Esther Burden-Teh, Ruth Murphy, Sonia Gran, Tamar Nijsten, Carolyn Hughes

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Scaling up the primary health integrated care project for chronic conditions in Kenya: study protocol for an implementation research project by Edwine Barasa, Ellen Nolte, Pablo Perel, Kara Hanson, Adrianna Murphy, Vincent Were, Antonio Gasparrini, Triantafyllos Pliakas, Robinson Oyando, Jemima H Kamano, Richard Mugo, Violet Naanyu, Anthony Etyang, Hillary Koros, Ruth Willis

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Implementation and impact of NHS-funded tobacco dependence services in England: a mixed-method evaluation protocol by Kate Jolly, Tomos Robinson, Sheena E Ramsay, Sarah Damery, Eileen F S Kaner, Sarah Flanagan, Chris Armitage, Jane West, Ailsa Rutter, Mackenzie Fong, Angela S Attwood, Sally Bridges, Angela Wearn, Maria Raisa Jessica Aquino, Theophile Bigirumurame, Kerry Brennan-Tovey, Samantha Russell, Miranda Trevor, Joanna Feeney, Ruth Sharrock, Steve Strong

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Vestibular Infant Screening-Rehabilitation (VIS-REHAB): protocol for a randomised controlled trial on Vestibular Rehabilitation Therapy (VRT) in vestibular-impaired children by Ruth Van Hecke, Leen Maes, Ingeborg Dhooge, Marieke Fontaine, Cleo Dhondt, Frederic Acke, Lena Van den Bossche, Helen Van Hoecke, Els De Leenheer

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Suicidal behaviour in adults during the COVID-19 pandemic: protocol for systematic review of observational studies by Fernando Jose Guedes da Silva Junior, Jaqueline Carvalho e Silva Sales, Claudete Ferreira de Souza Monteiro, Ana Paula Cardoso Costa, Luana Ruth Braga Campos, Priscilla Ingrid Gomes Miranda, Adriana da Cunha Menezes Parente, Larissa Alves de Araújo Lima, Aline Raquel de Sousa Ibiapina, Sandra Cristina Pillon, Angélica Martins de Souza Gonçalves, Chrystiany Plácido de Brito Vieira, Francisca Tereza de Galiza

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Evaluating the intended and unintended consequences of opioid-prescribing interventions on primary care in British Columbia, Canada: protocol for a retrospective population-based c... by Tara Gomes, Perry Kendall, M Ruth Lavergne, Dimitra Panagiotoglou, Rita McCracken, Erin C Strumpf, Benedikt Fischer, Austyn Brackett, Cheyenne Johnson

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Factors influencing the information behaviour of doctors and nurses in South Africa’s Eastern Cape, Mpumalanga, Limpopo and Northern Cape provinces: a survey study protocol by Sikhumbuzo A Mabunda, Wezile Chitha, Buyiswa Swartbooi, Itumeleng Funani, Lizo Godlimpi, Vivien Essel, Nombulelo Chitha, Onke Mnyaka, Jahman Thabede, Ruth Tshabalala

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Study protocol for a multi-session randomized sham-controlled trial of PCC- and amygdala-targeted neurofeedback for the treatment of PTSD by Jonathan M. Lieberman, Ruth A. Lanius, Jean Théberge, Benicio N. Frey, Paul A. Frewen, Frank Scharnowski, David Steyrl, Tomas Ros, Maria Densmore, Emma Tassinari, Vangel Matic, Niki Hosseini-Kamkar, Sandhya Narikuzhy, Fardous Hosseiny, Rakesh Jetly, Andrew A. Nicholson

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Heat Adaptation Benefits for Vulnerable groups In Africa (HABVIA): a study protocol for a controlled clinical heat adaptation trial by Michaela Deglon, Chad Africa, Larske Marit Soepnel, Thandi Kapwata, Ama de-Graft Aikins, Kweku Bedu-Addo, Guy Howard, Estelle Victoria Lambert, Dale Elizabeth Rae, Martha Sibanda, Christopher Gordon, Mark New, Lara Ruth Dugas

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Study protocol for a randomised controlled trial of a care partner assisted intervention to improve oral health of individuals with mild dementia by Bei Wu, Gary Yu, Brenda L Plassman, Patricia Poole, Shahrzad Siamdoust, Melanie Bunn, Bobbi Burwell, Yaolin Pei, Christine Downey, Danni Gomes, Angela Kamer, A Leak Bryant, Ruth A Anderson

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