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Using machine learning to discover DNA metabolism biomarkers that direct prostate cancer treatment
Published 2025-07-01“…Abstract DNA metabolism genes play pivotal roles in the regulation of cellular processes that contribute to cancer progression, immune modulation, and therapeutic response in prostate cancer (PC). …”
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663
The Role of Artificial Intelligence in Sports Analytics: A Systematic Review and Meta-Analysis of Performance Trends
Published 2025-06-01“…Sixteen peer-reviewed studies spanning 13 distinct sports disciplines were included, employing a variety of AI techniques—from classical machine learning algorithms to advanced deep learning and computer vision models. …”
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664
The role of the SOX2 gene in cervical cancer: focus on ferroptosis and construction of a predictive model
Published 2024-11-01“…This study delineates the role of SOX2 in the ferroptotic landscape of cervical carcinoma. …”
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Integrative multi-omics analysis reveals the role of toll-like receptor signaling in pancreatic cancer
Published 2025-01-01“…We explored the important role of TLR pathway in pancreatic cancer and established and validated a new prognosis model for pancreatic cancer based on TLR-related genes.…”
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667
Critical structural and functional roles for the N-terminal insertion sequence in surfactant protein B analogs.
Published 2010-01-01“…<h4>Background</h4>Surfactant protein B (SP-B; 79 residues) belongs to the saposin protein superfamily, and plays functional roles in lung surfactant. The disulfide cross-linked, N- and C-terminal domains of SP-B have been theoretically predicted to fold as charged, amphipathic helices, suggesting their participation in surfactant activities. …”
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668
Empowering Sustainability: The Crucial Role of IoT-Enabled Distributed Learning Systems in Reducing Carbon Footprints
Published 2025-01-01“…Electrical energy plays a pivotal role in modern society by powering homes, industries, and transportation systems. …”
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669
Autoencoder-Based Hyperspectral Unmixing with Simultaneous Number-of-Endmembers Estimation
Published 2025-04-01“…Hyperspectral unmixing plays a fundamental role in mining meaningful information from hyperspectral data. …”
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670
Generating Job Recommendations Based on User Personality and Gallup Tests
Published 2025-05-01“…While existing systems focus primarily on hard skills, this paper argues that personality traits—such as those measured by the Gallup test—play a crucial role in determining career satisfaction and long-term job retention. …”
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Quantifying Body Motion Synchrony in Autism Spectrum Disorder Using a Phase Difference Detection Algorithm: Toward a Novel Behavioral Biomarker
Published 2025-05-01“…ASD participants always assumed the listener role, enabling the isolation of receptive synchrony. …”
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674
Taylor-Spotted Cat Optimization (Taylor-SCO): An Energy-Efficient Cluster Head Selection Algorithm with Improved Trust Factor for Data Routing in WSN
Published 2024-01-01“…Moreover, the developed Taylor-SCO algorithm is developed by combining the Spotted Hyena Optimizer (SHO), Cat Swarm Optimization (CSO) algorithm, and Taylor series. …”
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675
Identification of immune-related biomarkers linked to systemic lupus erythematosus and dilated cardiomyopathy through integrated bioinformatics analysis and multiple machine learni...
Published 2025-07-01“…Additionally, we performed single-gene set enrichment analysis (GSEA) on key genes to elucidate their potential roles in SLE-related DCM. Finally, we applied the CIBERSORT algorithm to assess immune cell infiltration in both DCM and SLE patients.ResultsThrough DEG and WGCNA in the DCM and SLE datasets, we identified a total of 141 key module genes and 24 commonly expressed differentially expressed genes. …”
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676
Evaluating the role of land cover and climate uncertainties in computing gross primary production in Hawaiian Island ecosystems.
Published 2017-01-01“…Gross primary production (GPP) is the Earth's largest carbon flux into the terrestrial biosphere and plays a critical role in regulating atmospheric chemistry and global climate. …”
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677
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Leveraging AlphaFold2 structural space exploration for generating drug target structures in structure-based virtual screening
Published 2025-09-01“…Computational virtual screening (VS) plays a vital role in early-stage drug discovery by enabling the efficient selection of candidate compounds and reducing associated costs. …”
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679
EXTREME NORMOBLASTOSIS IN A THALASSAEMIA INTERMEDIA PATIENT POST-SPLENECTOMY: THE ROLE OF FLOW CYTOMETRY IN DIAGNOSIS AND MANAGEMENT
Published 2024-12-01“…The case also underscores the critical role of flow cytometry in diagnosing blood disorders and differentiating abnormal findings from potential malignancies. …”
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680
Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly.
Published 2020-01-01Get full text
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