Deep mutational scanning of the Trypanosoma brucei developmental regulator RBP6 reveals an essential disordered region influenced by positive residues by Saúl Rojas-Sánchez, Nikolay G. Kolev, Christian Tschudi

“…Expression of libraries containing all single-point variants of RBP6 in non-infectious procyclic forms and subsequent purification of infectious metacyclics supports the existence of an RNA-recognition motif (RRM) and reveal an N-terminal intrinsically disordered region (N-IDR). In contrast to the RRM, the N-IDR is more tolerant to substitutions; however, a handful of positions contain a third of all deleterious mutations found in the N-IDR. …”
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Future Changes in Surface Runoff over Korea Projected by a Regional Climate Model under A1B Scenario by Ji-Woo Lee, Suryun Ham, Song-You Hong, Kei Yoshimura, Minsu Joh

“…This study assesses future change of surface runoff due to climate change over Korea using a regional climate model (RCM), namely, the Global/Regional Integrated Model System (GRIMs), Regional Model Program (RMP). …”
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Creation of national regions as a means of ensuring rights and freedoms of Russian Germans: on the example of Azovsky Nemetsky (German) National District by M. S. Novikov

“…An analysis of the history of the creation of German national regions in the USSR shows a picture of the gradual assimilation of the German population or its migration outside the country. …”
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Neural tube defects in a war-torn Tigray regional state of Ethiopia: a retrospective study of 54,626 deliveries by Birhane Alem Berihu, Afework Mulugeta, Tony Magana, Masresha Tessema, Tafere Gebreegziabher, Yibrah Berhe, Abadi Leul Welderufael, Hayelom Kebede Mekonen

“…Abstract Background The Tigray region of Ethiopia has a significantly high prevalence of neural tube defects (NTDs), ranging from 1.31 to 2.15% of total births. …”
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Chronic Pain in the Emergency Department: A Pilot Mixed-Methods Cross-Sectional Study Examining Patient Characteristics and Reasons for Presentations by Patricia A. Poulin, Jennifer Nelli, Steven Tremblay, Rebecca Small, Myka B. Caluyong, Jeffrey Freeman, Heather Romanow, Yehudis Stokes, Tia Carpino, Amanda Carson, Yaadwinder Shergill, Ian G. Stiell, Monica Taljaard, Howard Nathan, Catherine E. Smyth

“…The most frequently cited reason (60%) for ED visits was inability to cope with pain. …”
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Industria automotriz en la región del TLCAN. Un análisis del valor agregado en las exportaciones bilaterales by Brenda Murillo-Villanueva, Yolanda Carbajal Suárez

“…El objetivo de este documento es descomponer las exportaciones bilaterales del sector automotriz en la región del TLCAN según el origen y usos del valor agregado a través de un modelo de insumo-producto multirregional. …”
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Referentes teórico-conceptuales y desarrollo de redes de las Pymes en el contexto local-regional-global by Ma. de Lourdes Ampudia Rueda

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Developing a method for diagnosing the level of the Kirov Region social and economic development within the Volga Federal District of the Russian Federation by R. S. Golovnin, T. V. Baibakova

Subjects: “…gross regional product…”
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Baltic Region in the View of French Historiography. - Rec.: Sylvain Gouguenheim. Les Chevaliers teutoniques. Paris: Tallandier, 2007. 775 p . by Tomas Čelkis

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Huawei y Foxconn: casos pioneros de la nueva internacionalización China y su impacto regional en México by Jorge Carrillo Viveros, Jordy Micheli Thirión

Subjects: “…desarrollo regional…”
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Sequence Analysis of How Disability Influenced Life Trajectories in a Past Population from the Nineteenth-Century Sundsvall Region, Sweden by Lotta Vikström, Helena Haage, Erling Häggström Lundevaller

“…Secondary findings concerning migration and mortality indicate that the disabled rarely out-migrated from the region, and they suffered from premature deaths. To our knowledge this is the first study to employ sequence analysis on a substantially large number of cases to provide demographic evidence of how disability shaped human trajectories in the past during an extended period of life. …”
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Research on Nonpoint Source Pollution Assessment Method in Data Sparse Regions: A Case Study of Xichong River Basin, China by Xing Liu, Donglong Li, Hongbo Zhang, Shixiang Cai, Xiaodong Li, Tianqi Ao

“…The proposed method with a main thought of combining and comparing an empirical model and a mechanistic model can assess the water quality conditions in the study area scientifically, which indicated it has a good potential for popularization in other regions.…”
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Seroprevalence of Cytomegalovirus, Toxoplasma gondii, Syphilis, and Hepatitis B and C Virus Infections in a Regional Population Seropositive for HIV Infection by Daniel G Johns, M John Gill

“…OBJECTIVE: To determine the prevalence of exposure to cytomegalovirus (CMV), Toxoplasma gondii, syphilis, hepatitis B virus (HBV) and hepatitis C virus (HCV) in a large, well characterized, regional population presenting for human immunodeficency virus (HIV) care.…”
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La ocupación del suelo en un municipio de la Región Metropolitana de Barcelona: desafíos y oportunidades by Anna Badia Perpinyà, Àngel Cebollada Frontera, Ana Vera Martín, Meritxell Gisbert Traveria, Enric Mendizábal Riera, Antoni Francesc Tulla Pujol

“…El objetivo general de este artículo consiste en analizar las dinámicas territoriales y del paisaje que han originado espacios vulnerables en un municipio de la Región Metropolitana de Barcelona, Matadepera, utilizando una metodología cuantitativa, para determinar la evolución de los CUCS a través de los Sistemas de Información Geográfica (SIG) y una cualitativa, para conocer la voz de la población residente a partir de entrevistas semiestructuradas. …”
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Study on the Synergistic Regulation Model for <i>Lycium barbarum</i> Berries Under Integrated Irrigation and Fertigation in Northwest Arid Regions by Yanlin Ma, Huile Lv, Yanbiao Wang, Yayu Wang, Minhua Yin, Yanxia Kang, Guangping Qi, Rong Zhang, Jinwen Wang, Junxian Chen

“…This study provides key insights for implementing integrated drip irrigation in northwest China’s arid regions.…”
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Social Environmental Support in Encouraging Entrepreneurial Behavior of Millennial Farmers in the Special Region of Yogyakarta, Indonesia: An Effort to Realize Sustainable Agriculture by Raden Rara Aulia Qonita, Masyhuri Masyhuri, Jamhari Jamhari, Hani Perwitasari

“…The research was conducted in the Special Region of Yogyakarta, Indonesia, which was the first province to inaugurate 1,000 millennial farmers. …”
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Adapting to ulcerative colitis to try to live a ‘normal’ life: a qualitative study of patients’ experiences in the Midlands region of England by Rachel Cooney, Christel McMullan, Dmitri Nepogodiev, Laura Magill, Thomas D Pinkney, Jonathan M Mathers, Laura L Jones, Shri Pathmakanthan

“…Objective To provide a framework that is able to categorise whether patients are able to adapt to and lead a ‘normal’ life with ulcerative colitis (UC) and to detail the factors that influence this.Design Qualitative research study using in-depth semi-structured interviews.Setting Four clinical sites in the West and East Midlands regions of England.Participants 28 adult patients diagnosed with UC for years between 1 and 22.Results Medication was rarely sufficient for patients to adapt to UC and live as ‘normal’ a life as possible. …”
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Structures and strategies for retaining an international pediatric cohort from birth: Lessons from The Environmental Determinants of Diabetes in the Young (TEDDY) study by Patricia Gesualdo, Jessica Melin, Rachel Karban, Claire Crouch, Michael Killian, Diane Hopkins, Annika Adamsson, Joanna Stock, Suzanne Bennett Johnson, Judith Baxter

“…The aim of this report is to describe the structures and strategies used to retain participants in The Environmental Determinants of Diabetes in the Young (TEDDY) Study, an observational study of children at increased genetic risk for type 1 diabetes followed in an intensive protocol from birth until age 15. …”
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Institutes for the new model of economic growth regional management development (territories of advanced development, territories of advanced social and economic development) by N. S. Stepanov

“…The instrument of this regulation is the functioning of institutions for the development of regional governance, which provide favorable conditions for doing business on special preferential terms. …”
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A Scale Development Study Regarding the Effects of Organized Industrial Zones on Regional Development: The Organized Industrial Zones Perception Scale by Ahmet Cem Esenlikci, Sedat Murat

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