uN2CpolyG-mediated p65 nuclear sequestration suppresses the NF-κB-NLRP3 pathway in neuronal intranuclear inclusion disease by Yu Shen, Kaiyan Jiang, Dandan Tan, Min Zhu, Yusen Qiu, Pencheng Huang, Wenquan Zou, Jianwen Deng, Zhaoxia Wang, Ying Xiong, Daojun Hong

“…Abstract Background Neuronal intranuclear inclusion disease (NIID) is genetically linked to CGG repeat expansion in the 5’-untranslated region of the NOTCH2NLC gene, with nascent polyglycine-containing protein (uN2CpolyG) identified as a primary pathogenic factor. …”
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Burden of micronutrient deficiency among patients with type 2 diabetes: systematic review and meta-analysis by Sanjay Kalra, Shiv Dutt Gupta, Daya Krishan Mangal, Diksha Gautam, Anuj Kumar Pandey, Nida Shaikh, Himanshu Tolani, Yeshwanth Sonnathi, Kamlesh Chand Sharma, Jagdish Prasad, Rajeev Tewari, Fahmina Anwar

“…The prevalence of micronutrient deficiency varied across WHO regions.Conclusions Micronutrient deficiencies were common in T2D patients, the most common being vitamin D deficiency. …”
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Assessment of Soil Erosion and Its Impact on Agricultural Productivity by Using the RMMF Model and Local Perception: A Case Study of Rangun Watershed of Mid-Hills, Nepal by Dinesh Bhandari, Rajeev Joshi, Raju Raj Regmi, Nripesh Awasthi

“…Soil erosion is a major concern for the environment and natural resources leading to a serious threat to agricultural productivity and one of the major causes of land degradation in the mid-hills region of Nepal. An accurate assessment of soil erosion is needed to reduce the problem of soil loss in highly fragile mountainous areas. …”
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Development of a novel instrument to measure Japanese psychiatric nurses’ technological competency as caring in nursing by Yoshiyuki Takashima, Hirokazu Ito, Gil P. Soriano, Yuko Yasuhara, Kyoko Osaka, Savina Schoenhofer, Tetsuya Tanioka

“…Results: The developed instrument comprises 22 items with a 4-factor structure: competency to practice caring and person-centered care (Factor 1); competency to recognize and respond to ethical issues in psychiatry (Factor 2); competency to utilize technology in psychiatry (Factor 3); and competence to practice care for the preservation of human dignity and shared decision making (Factor 4). …”
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Whether the Indications for Reverse Shoulder Arthroplasty Should Continue to Be Expanded? A Systematic Review and Meta‐Analysis by Huankun Li, Hangsheng Bao, Zhidong Yang, Baijun Hu, Yaocheng Pan, Yi Wang, Jiayi Chen, Hongjun Chen, Bisheng Shen, Yonggen Zou

“…Further meta regression analysis was conducted, considering factors such as region, age, gender ratio, and follow‐up time, excluding the influence of relevant factors. …”
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Bovine leukemia virus occurrence in Dagestan by N. R. Budulov, M. M. Mikailov, Sh. A. Gunashev, E. A. Yanikova, A. A. Halikov

“…Ninety-five bovine leukosis-affected localities were reported in the region as of 1 January 2022. Eighty-one new BLV-infected localities had been identified and bovine leukosis had been eliminated in 18 localities for 9 months of 2022. …”
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Indicators Of Morbidity And Mortality From Diseases of the Digestive System in the Krasnodar Krai and the Quality of Medical Care for Gastroenterological Patients by N. V. Korochanskaya, V. M. Durleshter, O. V. Kovalevskaya, S. N. Serikova, K. I. Popandopulo

“…Over the study period (13 years), the structure of mortality from DD has not changed significantly among the region’s population. About 70% of the causes of death from DD among people of working age account for liver diseases. …”
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Association of three single nucleotide polymorphisms in the <i>LPIN1</i> gene with milk production traits in cows of the Yaroslavl breed by A. V. Igoshin, T. M. Mishakova, R. B. Aitnazarov, A. V. Ilina, D. M. Larkin, N. S. Yudin

“…Blood samples from 142 cows of the Yaroslavl breed were obtained from two farms in the Yaroslavl region. Genotyping of SNPs was carried out by polymerase chain reaction-restriction fragment length polymorphism method. …”
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Consecuencias de la covid-19 en la economía y las finanzas públicas en México: más allá de la pandemia by Mario Alejandro Arellano Morales

“…La crisis sanitaria generada por la acelerada propagación en el planeta del virus SARS-CoV2 -fuente de la enfermedad covid-19- ha tenido un impacto negativo inevitable en los sistemas de salud y, simultáneamente, en la dinámica de las economías global, regional y nacional. Los problemas estructurales de la economía mexicana y la estrechez del espacio fiscal no surgieron con la pandemia, se fueron configurando durante las últimas tres décadas mediante la implementación del modelo económico que privilegió las políticas orientadas al mercado y el retiro de la intervención del Estado en la economía, en busca de una supuesta eficiencia en la asignación de los recursos y los factores productivos. …”
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Validity and Reliability of Dynamic and Functional Balance Tests in People Aged 19-54: A Systematic Review by Kim J Lesch, Sanni Tuomisto, Heikki O Tikkanen, Mika Venojärvi

“…The Nintendo Wii Balance Board also presents itself as a cost-effective and reliable tool for dynamic balance evaluation in clinical settings. It is crucial to recognize that these tests appraise discrete postural skills, preventing direct comparisons between test outcomes. …”
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Cardiovascular risk burden, dementia risk and brain structural imaging markers: a study from UK Biobank by Ting Li, Jing Chen, Yan Zheng, Klodian Dhana, Geng Zong, Yuan Ma, Trudy Voortman, Wei Gan, Yaying Cao, Yonghua Hu, Changzheng Yuan, Jie Shen, Gaohong Zhu, Chengwu Feng

“…Background Cardiovascular risk burden is associated with dementia risk and neurodegeneration-related brain structure, while the role of genetics and incident cardiovascular disease (CVD) remains unclear.Aims To examine the association of overall cardiovascular risk burden with the risk of major dementia subtypes and volumes of related brain regions in a large sample, and to explore the role of genetics and CVD onset.Methods A prospective study among 354 654 participants free of CVD and dementia (2006–2010, mean age 56.4 years) was conducted within the UK Biobank, with brain magnetic resonance imaging (MRI) measurement available for 15 104 participants since 2014. …”
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Exploring the impact of deleterious missense nonsynonymous single nucleotide polymorphisms in the DRD4 gene using computational approaches by Dipto Kumer Sarker, Pallobi Ray, Fayad Bin Abdus Salam, Shaikh Jamal Uddin

“…Five variants, including L65ICL1P (rs1459150721), V1163.33D (rs761875546), I1293.46S (rs751467198), I1564.46T (rs757732258), and F2015.47S (rs199609858), were identified as the most deleterious mutations that were also present in the conserved region and showed lower interactions with neighboring residues. …”
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Study on the Calibration Transfer of Soil Nutrient Concentration from the Hyperspectral Camera to the Normal Spectrometer by Xue-Ying Li, Guo-xing Ren, Ping-Ping Fan, Yan Liu, Zhong-Liang Sun, Guang-Li Hou, Mei-Rong Lv

“…In this paper, 164 soil samples from three regions in Qingdao, China, were collected. The spectral data of normal spectrometer and hyperspectral camera and the concentration of total carbon and nitrogen were obtained. …”
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Evaluating Dispersion of Residential CO and NOx Emissions with the Help of Different Models in Körfez District, Kocaeli Province by Kazım Demirarslan, Şenay Çetin Doğruparmak

“…Emissions from residential areas were chosen as the spatial source in the region and residents were divided into four different sections. …”
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Late initiation of antenatal care visit amid implementation of new antenatal care model in Sub-Saharan African countries: A multilevel analysis of multination population survey dat... by Kusse Urmale Mare, Gashaye Gobena Andargie, Abdulkerim Hassen Moloro, Ahmed Adem Mohammed, Osman Ahmed Mohammed, Beriso Furo Wengoro, Begetayinoral Kussia Lahole, Tesfahun Simon Hadaro, Simeon Meskele Leyto, Petros Orkaido Mamo, Abdulhakim Hora Hedato, Beminate Lemma Seifu, Temesgen Gebeyehu Wondmeneh, Oumer Abdulkadir Ebrahim, Kebede Gemeda Sabo

“…<h4>Introduction</h4>Although late initiation of antenatal care has been linked with adverse pregnancy outcomes, a significant number of pregnant women in resource-limited regions are seeking this care late. There has been a lack of information on the extent and factors influencing late initiation of antenatal care in the African context following the implementation of the new antenatal care model in 2016. …”
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Variability of the structure of correlations between the morphological and commercial traits of soybeans with different growth habit and branching characters by M. O. Burlyaeva, N. S. Rostova

“…Therefore, the  aim of the  present work was to study  the  variability of the  level (strength) and  the  structure of correlations between 92 morphological, phenological, biochemical,  agronomic traits of soybean accessions  with different  growth  habits,  and  branching characters in different weather conditions. 270 soybean accessions  of different ecological and geographical origin from the VIR collection  have  been  grown  in the  Krasnodar region  within 3 years. Field studies  of the  traits and biochemical  analysis were carried out according to VIR guidelines. …”
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Fear of Pain as a Predictor for Postoperative Pain Intensity among the Patients Undergoing Thoracoscopic Surgery by Yang Luo, Jingting He, Lihong Bao, Heng Meng, Cuihuan Hu, Quan Chen

“…Fear of pain (FOP) has been recognized as an influential moderator and determinant of the perception and disability of chronic pain. …”
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Relationship between CYP2C19 Polymorphism and Clopidogrel Resistance in Patients with Coronary Heart Disease and Ischemic Stroke in China by Rong Chang, Wenqin Zhou, Yi Ye, Xiaofei Zhang, Yanmin Liu, Jinchun Wu

“…The present study indicated that CYP2C19∗2, CYP2C19∗3, and CYP2C19∗17 alleles were not correlated with CR for both Han and Tibetan populations in Qinghai Province, while age, APTT, and aspirin resistance were independent risk factors of CR in this region.…”
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Application of complexity theory in health and social care research: a scoping review by Áine Carroll, Claire Collins, Andrew Darley, Diarmuid Stokes, Jane McKenzie

“…However, this scoping review has synthesised the most recent evidence and contributes to translational systems research by providing guidance for future studies.Conclusion The study of complex health and care systems necessitates methods of interpreting dynamic prcesses which requires qualitative and longitudinal studies with abductive reasoning. The authors provide guidance on conducting complexity-informed primary research that seeks to promote rigor and transparency in the area.Registration The scoping review protocol was registered at Open Science Framework, and the review protocol was published at BMJ Open (https://bit.ly/3Ex1Inu).…”
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Evaluation of the Availability and Implementation of Emergency Medical Services (EMS) Training in Saudi Emergency Medicine Programs by AlHussaini Z, Alsomali S, Ajaj Y, Jameel MA

“…For instance, ride-along (Air) was available in 7.1% of Eastern Region programs compared to 0% in Western programs. …”
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