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36461
HP1 Promotes the Centromeric Localization of ATRX and Protects Cohesion by Interfering Wapl Activity in Mitosis
Published 2025-01-01“…During mitosis, most ATRX proteins are removed from chromosomal arms, leaving a pool near the centromere region in mammalian cells, which is critical for accurate chromosome congression and sister chromatid cohesion protection. …”
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36462
Radiopharmacokinetic modelling and radiation dose assessment of 223Ra used for treatment of metastatic castration-resistant prostate cancer
Published 2021-06-01“…The time activity curves for 223Ra were modelled and the time integrated activity coefficients, a ~ r S T D , $$ \overset{\sim }{a}\left({r}_S,{T}_D\right), $$ in the source regions for each progeny were determined. For estimating the organ absorbed doses, the Specific Absorbed Fractions (SAF) and dosimetric framework of ICRP were used together with the aforementioned a ~ r S T D $$ \overset{\sim }{a}\left({r}_S,{T}_D\right) $$ values. …”
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36463
Influence of Ni, Al, W doping on microstructure, corrosion and wear resistance of HVOF spraying Fe-based amorphous alloy coatings
Published 2025-03-01“…The W-doped AAC showed the best performance than Ni-doped, Al-doped and base alloy AAC, with a wide passive region (ΔEpass) of 1.7 V, low self-corrosion current density (Icorr) of 1.07 × 10−6 A·cm−2 and the lowest steady-state current densities and highest passivation index. …”
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36464
Computational studies and structural insights for discovery of potential natural aromatase modulators for hormone-dependent breast cancer
Published 2024-09-01“…Generally 60%-75% of pre- and post-menopausal women suffer from estrogen-dependent breast cancer, and thus suppressing estrogen has been recognized to be a successful therapy. Hence, to limit the stimulation of estrogen, aromatase inhibitors (AIs) are used in the second-line treatment of breast cancer. …”
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36465
Revisiting teacher educators' training in Ethiopia: Implications for a new approach to curriculum development
Published 2023-06-01“…It was aimed at understanding the current status of science and mathematics teaching particularly in Amhara Regional State, Ethiopia so as to identify the existing gaps in the preparation of primary school science and mathematics teachers and teacher educators for Colleges of Teacher Education (CTE). …”
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36466
Scientific breeding of winter bread wheat in the Non-Сhernozem zone of Russia: the history, methods and results
Published 2021-07-01“…Produced in the 2000s, cvs Moskovskaya 56, Nemchinovskaya 57, Galina, Nemchinovskaya 24, Nemchinovskaya 17, and Moskovskaya 40 have a high adaptability to the environment of the region; give a high yield and quality of grain. The area of crops of these cultivars in Russia occupies more than 2 million ha. …”
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36467
Optimizing growth, yield, and water use efficiency of Allium hirtifolium with salicylic acid under water stress condiions
Published 2025-01-01“…Water stress significantly limits the growth and productivity of crops, particularly medicinal plants in arid and semi-arid regions. This study explores the use of salicylic acid (SA) as a means to enhance shallot (Allium hirtifolium) resistance to water stress, as well as improve growth, yield, and water use efficiency (WUE) under various irrigation levels. …”
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36468
Peculiarities of Legal Regulation of Non-Discrimination on Gender Basis while Being Employed
Published 2021-07-01“…It has been determined that an unjustified refusal to be hired should be considered a refusal that is devoid of any motivation or when an employer refuses a candidate for reasons other than his professional and business qualities, or does not take into account a number of special requirements provided by the current legislation. …”
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36469
Detection of low frequency artemisinin resistance mutations, C469Y, P553L and A675V, and fixed antifolate resistance mutations in asymptomatic primary school children in Kenya
Published 2025-01-01“…Conclusion The genomic surveillance of asymptomatic school children in Kenya provides an early warning signal of at least 1 of the 3 validated artemisinin resistance mutations circulating in all regions in Western Kenya sampled except Homa Bay and Kisii Counties. …”
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36470
The effect of counseling with a positive approach on anxiety about giving birth to an Infant with Anomalies in pregnant mothers over 35 years of age
Published 2024-11-01“…Since advanced maternal age is recognized as a risk factor for adverse pregnancy outcomes and fetal complications, there is a heightened potential for increased anxiety and worry among those who become pregnant at older age. …”
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36471
Congenital Bullous Syphilis: A Case Report from Italy and a Comprehensive Literature Review
Published 2025-01-01“…Although many infants appear asymptomatic at birth, subtle clinical signs—including bullous lesions (congenital bullous syphilis, also known as pemphigus syphiliticus)—may facilitate early detection. Recognizing this rare manifestation is crucial for timely intervention, reducing serious outcomes. …”
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36472
Global decadal measurements of methanol, ethene, ethyne, and HCN from the Cross-track Infrared Sounder
Published 2025-02-01“…The results reveal robust global distributions of the target VOCs from known biogenic, biomass burning, and industrial source regions, and they demonstrate the impact of anomalous events such as the 2015–2016 El Niño. …”
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36473
Pathological Characteristics, Prognostic Determinants and the Outcome of Patients Diagnosed with Colorectal Adenocarcinoma at the University Teaching Hospital of Kigali
Published 2022-01-01“…It is known that colorectal cancer is common in developed countries than in developing countries which may be due to inaccurate data on the existence of the disease in that region combined with embracing western lifestyle expressed by the current trend of changes in cultural, social, and lifestyle practices playing a major part in the etiology of CRC. …”
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36474
Design and Test of a Cone Dielectric Elastomer Actuator Driving Hopping Robot
Published 2024-12-01“…Dielectric elastomer actuators (DEAs) are increasingly recognized for their potential in robotic applications due to their ability to undergo significant deformation when subjected to an electric field. …”
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36475
Efficacy of Simple Eye Ointment, Polyethylene Cover, and Eyelid Taping in Prevention of Ocular Surface Disorders in Critically Ill Patients: A Randomized Clinical Trial
Published 2020-01-01“…However, patients admitted to the intensive care unit (ICU) for several reasons including loss of consciousness, receiving sedative and neuromuscular blocking agents, and mechanical ventilation may lose eye-protective mechanisms causing exposure keratopathy. …”
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36476
Feline mastocytoma. Case report
Published 2020-01-01“…Se presenta un caso de mastocitoma felino correspondiente a un ejemplar mestizo con cuadro clínico de inicio de más de dos meses de evolución, consistente en la aparición de una placa alopécica ulcerada y elevada en región interescapular, acompañada de prurito que presentó resolución espontánea. …”
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36477
Uncovering novel functions of the enigmatic, abundant, and active Anaerolineae in a salt marsh ecosystem
Published 2025-01-01“…The data revealed that the belowground salt marsh Anaerolineae in the rhizosphere are important players in carbon cycling, including degradation of simple carbon compounds and more recalcitrant plant material, such as cellulose, using a diversity of electron acceptors and represent an unexplored reservoir of novel secondary metabolites.IMPORTANCEGiven that coastal salt marshes are recognized as biogeochemical hotspots, it is fundamentally important to understand the functional role of the microbiome in this ecosystem. …”
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36478
Management of sudden sensorineural hearing loss among primary care physicians in Canada: a survey study
Published 2021-04-01“…Primary care physicians are likely the first to be presented with SSNHL and therefore have the crucial role of recognizing it and initiating timely and appropriate management. …”
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36479
Evolución del Empleo en el Sector Terciario en Venezuela
Published 2006-01-01“…Como lo hace (Weller, 2004), se compara, la evidencia empírica sobre la evolución del empleo en el sector terciario a nivel mundial, preguntándose sí Venezuela muestra características especiales y, sobre todo, si los datos apoyan o no la tesis de una diferencia fundamental entre la terciarización en los países industrializados y aquella en la región latinoamericana y caribeña (terciarización genuina contra terciarización espuria), específicamente en Venezuela. …”
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36480
Acute hepatitis of non-specified etiology
Published 2011-02-01“…As a result of the study within the group of patients with acute hepatitis, that never visited precinctive regions, viral hepatitis Е was revealed by EIA in 4,8% of cases, including 2,4% when it was detected both by EIA and PCR. …”
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