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25941
Risk Assessment of Water and Sand Inrush in Mining under Thick Loose Layer Based on Comprehensive Weight-Cloud Model
Published 2023-01-01“…A comprehensive weighting method, which combines analytic hierarchy process (AHP), entropy weight method (EWM), and minimum entropy principle, is used to reasonably assign the weight of index. Based on the cloud generator equation, the membership function is obtained. …”
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25942
Evaluation of fluoride releasing and recharging of orthodontic adhesive resins: An in vitro study.
Published 2021-02-01“… Background and objective: Development of white spot lesions to be a well-recognized and common side effect of orthodontic fixed appliance, in spite of vast improvement in preventive dental techniques and procedures. …”
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25943
Search for the turning points in the Soviet Lithuanian historiography: 1956 (?)
Published 2007-12-01“…The elite of LCP ruined the possibility of radical changes by supporting Žiugžda and his scientific opponents were accused of "bourgeois nationalism". For this reason, the year 1956 in Lithuanian Soviet historiography did not become the beginning of radical changes but rather the period of status quo. …”
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25944
Excès et sacré dans la littérature victorienne et édouardienne
Published 2006-12-01“…Unlike her sisters, Emily Brontë stands, in her solitude, for some form of sacred violence and for the rejection of the identification of God with reason. This means that we are confronted with two sorts of Victorian writers : those who assimilate and swallow as opposed to those who « vomit ». …”
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25945
Gut mycobiome alterations and network interactions with the bacteriome in patients with atherosclerotic cardiovascular disease
Published 2025-01-01“…While the role of the gut microbiome in ACVD development is recognized, the contribution of the gut mycobiome remains largely unexplored. …”
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25946
SMAC-armed oncolytic virotherapy enhances the anticancer activity of PD1 blockade by modulating PANoptosis
Published 2025-01-01“…Abstract Background Oncolytic viruses (OVs) are increasingly recognized as promising tools for cancer therapy, as they selectively infect and destroy tumor cells while leaving healthy cells unharmed. …”
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25947
Activities of Detective Units in the National Police of Ukraine: Current Status and Perspectives
Published 2021-07-01“…The adoption of the Law "On Private Detective Activity" will allow to establish proper state control over this type of activity at the legislative level and will legalize private detective activity, which is actually carried out, is in demand and recognized by society. However, there is an indisputable opinion in Ukraine that law enforcement activities can be performed exclusively by state structures. …”
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25948
Overexpression of miR-124 enhances the therapeutic benefit of TMZ treatment in the orthotopic GBM mice model by inhibition of DNA damage repair
Published 2025-01-01“…Taken together, we rationally explained a novel and important mechanism of the miR-124-mediated high sensitivity to TMZ-induced cell death in GBM and provided evidence to support that miR-124-RAD51 regulatory axis could be a promising candidate in the comprehensive treatment with TMZ in GBM.…”
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25949
The Effect of Maximal Leg Press Strength Training on Bilateral Deficit
Published 2014-11-01“…The purpose of this study was to determine maximal isometric strength with bilateral and unilateral muscle contractions and investigate maximal strength training whether or not influenced on this bilateral deficit. For this reason, 34 amateur soccer player (age = 17 ± 2.51 years) were divided into three groups as bilateral training group (n=14), unilateral training group (n=10) and control group (n=10). …”
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25950
Retrospective Study Comparing Clinical Outcomes of Fixed Dental Prostheses in Matched Groups of Bruxer and Nonbruxer Patients
Published 2022-01-01“…Loss of retention and tooth loss were the main reasons for failures in both groups. For nonsmokers, the FDP failure rate was higher in nonbruxers. …”
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25951
Differential gene expression during recall of behaviorally conditioned immune enhancement in rats: a pilot study [version 3; peer review: 1 approved, 3 approved with reservations]
Published 2025-01-01“…In the pituitary, we recognized mostly upregulation of steroid synthesis in combination with GABAergic, cholinergic and opioid related neurotransmission, in adrenal glands, altered genes showed a pattern of activated metabolism plus upregulation of adrenoceptors Adrb3 and Adra1a. …”
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25952
Od adaptacji do edukacji, czyli plakaty filmowe w praktyce szkolnej
Published 2023-12-01“…The author begins by explaining the reason for choosing this topic, which she sees primarily in the fact that, according to her own observations and research, students do not encounter the analysis of film posters in school, nor do they have a desire to respond to the demands of other researchers in the field of Polish language teaching. …”
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25953
Modelling the potential clinical and economic impact of universal antenatal hepatitis C (HCV) screening and providing treatment for pregnant women with HCV and their infants in Egy...
Published 2024-04-01“…Findings were robust to reasonable changes in parameters.Conclusion Universal screening and treatment of HCV in pregnancy, with treatment of infected infants at age 3 years is cost saving compared with current practice in the Egyptian setting.…”
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25954
CADD-based discovery of novel oligomeric modulators of PKM2 with antitumor activity in aggressive human glioblastoma models
Published 2025-02-01“…These effects were directly linked to their inhibition of PKM2 enzymatic activity, validating the proposed mechanism of action in their rational design. ADMET studies further highlighted their strong potential as lead PKM2 inhibitors for GBM treatment.Molecular dynamics (MD) simulations and post-MD analyses, including Dynamic Cross-Correlation Maps (DCCM), Probability Density Function (PDF), and Free Energy Landscape (FEL), confirmed the stability of the protein-ligand interactions and highlighted critical residues at the dimer-dimer interface. …”
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25955
Phylogenetic analysis and detection of positive selection in the SIRT gene family across vertebrates
Published 2025-01-01“…Abstract SIRT6, a member of the sirtuin protein family, is recognized as a tumor suppressor. This study investigates the evolutionary history of the SIRT gene family and examines the selective pressures shaping their functional divergence. …”
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25956
Simulating the Tone River eastward diversion project in Japan carried out 4 centuries ago
Published 2025-02-01“…First, we confirmed that our modeling framework reasonably reproduced the present river flows by adding two present-day bifurcation functions. …”
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25957
Analysis of the Influence of Groundwater Level Fluctuation on Karst Soil Cave Collapse
Published 2023-01-01“…It will provide essential theoretical support for further research on the action law of hydrodynamic factors on karst collapse and a scientific and reasonable basis for urban groundwater pumping control, karst and roadbed collapse prevention and prediction.…”
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25958
Investigating the Construction Procedure and Safety Oversight of the Mechanical Shaft Technique: Insights Gained from the Guangzhou Intercity Railway Project
Published 2025-01-01“…The achievements include a 22.22% reduction in construction time, a 20.27% decrease in investment, and lower worker risk. (2) Monitoring confirmed that all cutting edge and segment values remained safe, demonstrating the method’s feasibility and rationality. (3) Analyzing shaft monitoring data and field uncertainties, this study proposes recommendations for future work, including precise segment lowering control and introducing high-precision total stations and GPS technology to mitigate tunneling and assembly inaccuracies. …”
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25959
Refining Sparse Cell-ID Trajectory of Public Service Vehicles by Spatiotemporal Modelling
Published 2021-01-01“…So, the cell-id trajectory refinement has been recognized as challenging work to further facilitate trajectory data mining. …”
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25960
Strategies for H-score Normalization of Preanalytical Technical Variables with Potential Utility to Immunohistochemical-Based Biomarker Quantitation in Therapeutic Reponse Diagnost...
Published 2011-01-01“…While patient H-scores vary for biological reasons, variation may also arise from preanalytic technical issues, such as differences in fixation protocols. …”
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