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Age and sex specific thresholds for risk stratification of cardiovascular disease and clinical decision making: prospective open cohort study
Published 2024-12-01“…Objective To quantify the potential advantages of using 10 year risk prediction models for cardiovascular disease, in combination with risk thresholds specific to both age and sex, to identify individuals at high risk of cardiovascular disease for allocation of statin treatment.Design Prospective open cohort study.Setting Primary care data from the UK Clinical Practice Research Datalink GOLD, linked with hospital admissions from Hospital Episode Statistics and national mortality records from the Office for National Statistics in England, 1 January 2006 to 31 May 2019.Participants 1 046 736 individuals (aged 40-85 years) with no cardiovascular disease, diabetes, or a history of statin treatment at baseline using data from electronic health records.Main outcome measures 10 year risk of cardiovascular disease, calculated with version 2 of the QRISK cardiovascular disease risk algorithm (QRISK2), with two main strategies to identify individuals at high risk: in strategy A, estimated risk was a fixed cut-off value of ≥10% (ie, as per the UK National Institute for Health and Care Excellence guidelines); in strategy B, estimated risk was ≥10% or ≥90th centile of age and sex specific risk distributions.Results Compared with strategy A, strategy B stratified 20 241 (149.8%) more women aged ≤53 years and 9832 (150.2%) more men aged ≤47 years as having a high risk of cardiovascular disease; for all other ages the strategies were the same. …”
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Prognostic value of EMT-related genes and immune cell infiltration in thyroid carcinoma
Published 2024-11-01Get full text
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Metabolism and Microstructure of the Small Intestine Wall in Patients With Colorectal Cancer
Published 2023-07-01Get full text
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Practical application of national clinical guidelines for the management of gout (preliminary data)
Published 2020-05-01Get full text
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Penerapan Feature Engineering dan Hyperparameter Tuning untuk Meningkatkan Akurasi Model Random Forest pada Klasifikasi Risiko Kredit
Published 2025-04-01“…This research aims to improve the accuracy of the Random Forest algorithm classification model by implementing parameter tuning and feature engineering. …”
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Damage prediction of rear plate in Whipple shields based on machine learning method
Published 2025-08-01“…Current hypervelocity impact research primarily focuses on the interaction between projectile and front plate and the movement of debris cloud. …”
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Modified Diagnostic Criteria Tools for Familial Hypercholesterolemia without the Requirement for Clinical Genetic Testing: Rationale and Design of the MOOCS Adaptive Clinical Trial
Published 2024-10-01“…Because of this issue, research groups cannot appropriately score such patients. …”
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Human-Annotated Label Noise and Their Impact on ConvNets for Remote Sensing Image Scene Classification
Published 2025-01-01“…Additionally, the label noise estimation algorithm (confident learning) cannot fully identify label noise. …”
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Clear Cell Acanthoma/Pseudolymphoma: Clinical Dermatoscopic and Histological Correlation
Published 2019-04-01“…Content analysis, method of system and comparative analysis, bibliosemantic method of studying of relevant scientific research were used. The search for sources was carried out in scientometric med ical information bases: PubMedNCBI, Medline, CochraneLibrary, EMBASE, ResearchGate in accordance with the keywords: clear cell acanthoma, pseudolymphoma, dermatoscopy. …”
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Large-Scale Monitoring of Potatoes Late Blight Using Multi-Source Time-Series Data and Google Earth Engine
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THE PERCENTAGE AND STRUCTURE OF PERODONT TISSUE DISEASES IN PATIENTS OF LVIV REGIONAL STATIONARY CLINICAL HOSPITAL DEPENDING ON AGE
Published 2018-12-01“…To study the prevalence and structure of periodontal tissue lesions in patients with general - somatic diseases in order to develop a therapeutic algorithm in a hospital setting. Materials and methods. …”
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Enhancing heat transfer in compound twisted square ducts using shortened twisted tape inserts
Published 2025-06-01“…This research offers insights into optimizing heat exchanger design using twisted square ducts. …”
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Modeling of strike drone missions for conducting wave attacks in conditions of enemy anti-drone actions
Published 2025-02-01“…The actual problem of studying military logistics actions to form missions of a swarm of attack drones for conducting massive attacks on enemy targets is formed and solved. The research is aimed at planning military attacks with drones to provide for establishing military parity of forces in a military conflict zone. …”
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