Optimizing alginate extraction using Box-Behnken design: Improving yield and antioxidant properties through ultrasound-assisted citric acid extraction by Letícia Rustici Chica, Camila Yamashita, Natalie Stephanie Sawada Nunes, Arthur Torres Negreiros, Izabel Cristina Freitas Moraes, Antônio Gilberto Ferreira, Cassia Roberta Malacrida Mayer, Charles Windson Isidoro Haminiuk, Ciro Cesar Zanini Branco, Ivanise Guilherme Branco

“…The Box-Behnken Design was employed to optimize the extraction of alginate (ALG) from Sargassum cymosum C. …”
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Optimizing polyphenol extraction from Anacyclus pyrethrum var. depressus (Ball) Maire roots: a simplex-centroid mixture design approach by Oumaima Chater, Smail Aazza, Hiba Bouzaid, Lahsen El Ghadraoui

“…Conclusion: With this type of research, it would be easier to treat and prevent human damage from free radicals and also replace synthetic antioxidants in industry.…”
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Response Surface Methodology Approach for the Prediction and Optimization of the Mechanical Properties of Sustainable Laterized Concrete Incorporating Eco-Friendly Calcium Carbide... by Auwal Ahmad Khalid, Abdurra’uf. M. Gora, A. D. Rafindadi, Sadi I. Haruna, Yasser E. Ibrahim

“…These optimization outcomes produced the most robust possible results, with a desirability of 81.3%.…”
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Application of Real-Time Palm Imaging with Nelder–Mead Particle Swarm Optimization/Regression Algorithms for Non-Contact Blood Pressure Detection by Te-Jen Su, Ya-Chung Hung, Wei-Hong Lin, Wen-Rong Yang, Qian-Yi Zhuang, Yan-Xiang Fei, Shih-Ming Wang

“…The NM-PSO approach emphasizes optimization in noise handling, while the regression method leverages formulaic efficiency in BP estimation. …”
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Enhanced YOLO11n-Seg with Attention Mechanism and Geometric Metric Optimization for Instance Segmentation of Ripe Blueberries in Complex Greenhouse Environments by Rongxiang Luo, Rongrui Zhao, Bangjin Yi

“…The DAB module combines channel–spatial attention and structural reparameterization techniques. This optimizes the YOLO11n structure and effectively suppresses background interference. …”
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GNSS time series analysis of the crustal movement network of China: Detecting the optimal order of the polynomial term and its effect on the deterministic model by Shuguang Wu, Hua Ouyang, Houpu Li, Zhao Li, Haiyang Li, Yuefan He

“…This finding reminds us that the detection of the optimal-order polynomial is necessary when we aim to acquire an accurate understanding of the crustal movement features.…”
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Optimal early endpoint for second-line or subsequent immune checkpoint inhibitors in previously treated advanced solid cancers: a systematic review by Jingqiu Li, Xiaoding Zhou, Lei Wu, Jiabao Ma, Yan Tan, Songke Wu, Jie Zhu, Qifeng Wang, Qiuling Shi

“…However, early efficacy endpoints are not recommended in RCTs to replace OS.…”
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Engineered Passive Glucose Uptake in Pseudomonas taiwanensis VLB120 Increases Resource Efficiency for Bioproduction by Tobias Schwanemann, Nicolas Krink, Pablo I. Nikel, Benedikt Wynands, Nick Wierckx

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Research of billing method for electric vehicle swapping based on the charging capacity by ZHANG Yahao, ZHANG Hang, WANG Zhaoqing, LIU Xiangli, CHEN Lei, ZHAO Jiangxin

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Performance analysis of high-rate generalized space code index modulation system by BIAN Lina, ZHANG Qianyu, WU Jiayan

“…The traditional modulation symbols were replaced with the additional phase by the HR-GS-CIM system, and the genetic algorithm (GA) was used to optimize the design of the additional phase, which could acquire high energy efficiency advantage and performance advantage. …”
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Screening for a Reweighted Penalized Conditional Gradient Method by Sun, Yifan, Bach, Francis

“…The conditional gradient method (CGM) is widely used in large-scale sparse convex optimization, having a low per iteration computational cost for structured sparse regularizers and a greedy approach for collecting nonzeros. …”
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Algorithm of Estimating Import-Substitution Based on Costs – Output Tables by N. A. Moiseev, B. A. Akhmadeev

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Mechanical and durability performance of cementitious matrices with low cement and different additions by Eliana Soldado, Ana Antunes, Hugo Costa, Ricardo Carmo, Eduardo Júlio

“…Knowing that Portland cement is responsible for significant anthropogenic emissions worldwide, the optimization of cement dosage on concrete mixtures is a key issue, combined with the mechanical and durability performances, allowing to improve its eco-efficiency. …”
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Innovative and best practices in sustainable strategies for waste reduction in additive manufacturing by Kazeem Aderemi Bello, Rendani Wilson Maladzhi

“…The increasing adoption of additive manufacturing (AM) to replace the traditional subtractive manufacturing process has gained traction owing to its numerous advantages. …”
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Complex Path Planning for Manipulators Based on an Improved NSGA-III Algorithm With Hopfield Network by Xiaoxiang Sun, Jue Wang, Wei Wang

“…We introduce a Hopfield neural network to replace the initial random sampling of the NSGA-III algorithm, allowing for the rapid generation of an initial optimized population. …”
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Enhancing Energy Efficiency of Electric Grade Isopropyl Alcohol Production Process by Using Noble Thermally Coupled Distillation Technology by Neha Agarwal, Nguyen Nhu Nga, Le Cao Nhien, Raisa Aulia Hanifah, Minkyu Kim, Moonyong Lee

“…This study presents a comprehensive design, optimization, and intensification approach for enhancing the energy efficiency of electric grade isopropyl alcohol (IPA) production, a typical energy-intensive chemical process. …”
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Synergistic Effects of Alkali Activator Dosage on Carbonation Resistance and Microstructural Evolution of Recycled Concrete: Insights from Fractal Analysis and Optimal Threshold Id... by Yier Huang, Aimin Gong, Zhuo Jin, Yulin Peng, Shanqing Shao, Kang Yong

“…These findings establish 8% as a critical threshold for optimizing alkali activation efficiency and durability in low-carbon concrete design. …”
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Generation of human iPSC-derived pancreatic organoids to study pancreas development and disease [version 1; peer review: 2 approved, 2 approved with reservations] by Francesca Maria Spagnoli, Abigail Isaacson, Jean-Francois Darrigrand

“…Lastly, we anticipate that this system will contribute to the replacement of animal models used to investigate diseases, such as pancreatic cancer.…”
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An advanced approach to predicting optimal material compositions for graphene/carbon black reinforced polypropylene/polyvinyl chloride nanocomposites focusing mechanical and econom... by Utkarsh Patil, Pravin Kubade

“…The results are validated by varying mesh sizes to optimize deflection and Von Mises s tress predictions. …”
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Risk Assessment and Recommended Approaches to Optimize Infection Control and Antibiotic Stewardship to Reduce External Ventricular Drain Infection: A Single-Center Study by Jozsef Kelemen, Marton Sztermen, Eva Dakos, Gergely Agocs, Jozsef Budai, Jozsef Katona, Zsuzsanna Szekeressy, Laszlo Sipos, Zoltan Papp, Mate Bata, Janos Karczub, Mate Korompai, Zsuzsanna A. Dunai, Bela Kocsis, Dora Szabo, Lorand Eross

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