An imidazoline receptor agonist, moxonidine, in optimization of arterial hypertension treatment among postmenopausal women by A. B. Bakhshaliev, G. M. Sabzalieva, T. Sh. Dzhakhangirov

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Optimizing laying hen diets: effect of partial maize meal replacement with wheat bran or biscuits crumbs and Bacillus amyloliquefaciens CECT 5940 by Albertina Felizardo Manteiga, Abilio Paulo Changule, Dercia Hilario Magaia, Nilza Jorge Manjate, Florentina Domingos Chilala, Leonel António Joaquim, Leonel António Joaquim, Eunice Justino Chivale, Filomena Dos Anjos, Otilia Henrique Tamele Tomo, Manuel Garcia-Herreros, Manuel Garcia-Herreros, Custodio Bila, Custodio Bila, Custodio Bila, Custodio Bila

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Artificial Intelligence Enabled Fully Automated CMR Function Quantification for Optimized Risk Stratification in Patients Undergoing Transcatheter Aortic Valve Replacement by Ruben Evertz, Torben Lange, Sören J. Backhaus, Alexander Schulz, Bo Eric Beuthner, Rodi Topci, Karl Toischer, Miriam Puls, Johannes T. Kowallick, Gerd Hasenfuß, Andreas Schuster

“…In addition to significant time saving, this may provide the tools for optimized clinical management and stratification of patients with severe AS undergoing TAVR.…”
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Optimizing clinical outcomes: The journey of twins with CRIM-negative infantile-onset Pompe disease on high-dose enzyme replacement therapy and immunomodulation by Angie H. Fares, Ankit K. Desai, Laura E. Case, Cassie Sharon, Amy Klinepeter, Amelia Kirby, Matthew T. Lisi, Rebecca L. Koch, Priya S. Kishnani

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Analysis of results to optimize anticoagulant therapy in patients who underwent mechanical heart valve replacement: a pilot singlecenter controlled study by S. A. Uranova-Tkachenko, A. V. Bogachev-Prokophiev, R. M. Sharifulin, Y. M. Smirnov, A. N. Pivkin, A. S. Zalesov, D. A. Astapov

“…Notably, the majority of these events consisted of ischemic strokes, which occurred in 5% of the study group. Consequently, the optimal target INR range for patients who have undergone heart valve replacement with mechanical prostheses remains inadequately defined…”
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Cell cultures in replacement therapy by E. M. Petruchuk, N. V. Shalunova, Yu. V. Olefir, I. V. Borisevich, V. V. Perekrest, V. A. Shevtsov, A. V. Rukavishnikov, L. M. Khantimirova

“…The therapeutic potential of fibroblasts related to optimization of reparative processes, improvement of regenerative and adaptive capabilities, as well as the accumulated experience of their clinical use are stirring interest to the development of fibroblast-based biomedical cell products and their use as replacement therapy. …”
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HitShield: Enhanced Swap Eviction Scheme for Multi-Generational LRU by Minwoo Jo, Binwon Song, Hayong Jeong, Heeseung Jo

Subjects: “…Page replacement algorithm…”
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Patients Refusing Transcatheter Aortic Valve Replacement Even Once Have Poorer Clinical Outcomes by Tetsuro Shimura, Masanori Yamamoto, Seiji Kano, Soh Hosoba, Mitsuru Sago, Ai Kagase, Yutaka Koyama, Satoshi Tsujimoto, Toshiaki Otsuka, Norio Tada, Toru Naganuma, Motoharu Araki, Futoshi Yamanaka, Shinichi Shirai, Kazuki Mizutani, Minoru Tabata, Hiroshi Ueno, Kensuke Takagi, Akihiro Higashimori, Yusuke Watanabe, Kentaro Hayashida

Subjects: “…Optimized Catheter Valvular Intervention…”
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Minimizing the eccentricity between the centers of mass and stiffness of structures with the optimality criterion method in the structural design process by Reza Akbari, Payam Gholbeigi

Subjects: “…optimality criteria…”
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Optimizing Continuous Renal Replacement Therapy with Regional Citrate Anticoagulation: Insights from the ORCA Trial—A Retrospective Study on 10 Years of Practice by Rita Jacobs, Walter Verbrugghe, Jason Bouziotis, Ingrid Baar, Karolien Dams, Annick De Weerdt, Philippe G. Jorens

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Optimizing Bioceramic Composites for Hip Joint Replacements using SPS Method: Investigating the Effects of Titanium Diboride (TiB2) on Tribological Properties by Pavankumar Ravikumar, Goud Mallesh, S. Suresh Kumar, H. S. Manjunatha

“…This study investigates the fabrication, characterization, and tribological behavior of bioceramic composites specifically engineered for hip joint replacements. Utilizing the Spark Plasma Sintering (SPS) process, advanced ceramic composites were developed, comprising alumina (Al2O3), silicon carbide (SiC), magnesium oxide (MgO), and titanium diboride (TiB2) integrated with an Al6061 base. …”
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Case Report: Optimized guidewire pacing in transcatheter aortic valve replacement combined with complex PCI in a patient with severe aortic stenosis and regurgitation by Ruisong Ma, Ruisong Ma, Ruisong Ma, Ruisong Ma, Ruisong Ma, Wang Liao, Wang Liao, Wang Liao, Wang Liao, Wang Liao, Lili Zhang, Lili Zhang, Lili Zhang, Lili Zhang, Lili Zhang, Sheng Wang, Sheng Wang, Sheng Wang, Sheng Wang, Sheng Wang

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What Is the Optimal Mitral Valve Repair for Isolated Posterior Leaflet Prolapse to Achieve Long‐Term Durability? by Takashi Kakuta, Satsuki Fukushima, Kimito Minami, Satoshi Kainuma, Naonori Kawamoto, Naoki Tadokoro, Ayumi Ikuta, Kohei Tonai, Yoshikatsu Saiki, Tomoyuki Fujita

“…Conclusions Leaflet resection with a large partial band may be an optimal strategy for isolated posterior mitral valve prolapse.…”
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Optimization of production well patterns for natural gas hydrate reservoir: Referring to the results from production tests and numerical simulations by Lang-feng Mu, Hao-tian Liu, Chi Zhang, Yi Zhang, Hai-long Lu

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Reverse optimum safety factor approaches as effective tools for reliability-based topology optimization with application to cementless hollow stems used in total hip replacement by Ghais Kharmanda, Hasan Mulki

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A resorbable scaffold for bone replacement by Paola Andrea Bustamante, Maria Carolina Anessi

“…In this way, our biomaterial seems to be good for scaffolds for bone replacement.…”
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Optimizing sustainable concrete mixes with recycled aggregate and Portland slag cement for reducing environmental impact by Lamiaa Ismail, Mohamed Abdel Razik, El Sayed Ateya, Ahmed Said

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Allergic seasonal blepharoconjunctivitis therapy optimization in conditions of dry eye and meibomian glands dysfunctions by S. V. Yanchenko, A. V. Malyshev, Sh. J. Teshaev, S. S. Davlatov, M. Yu. Odilov, E. A. Haribova, L. M. Petrosyan, R. R. Boboeva

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Multi-objective optimization of cushion gas design in underground gas storage using machine learning by Mohaddeseh Ahmadi Aghdam, Maryam Fazaeli, Mahdi Kanaani, Behnam Sedaee

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A comparative study on utilization of different plant-derived nano-mucilage as a fat replacer in yogurt: Product optimization, physicochemical attributes, shelf-life evaluation, and consumer perception with market orientation by Mansuri M. Tosif, Aarti Bains, Gulden Goksen, Mohd Ziaur Rehman, Nemat Ali, Gulsah Karabulut, Prince Chawla

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