Impact of artemether–lumefantrine treatment, circadian rhythm, and serum replacement on the infectiousness of wild Plasmodium falciparum gametocytes to Anopheles gambiae sensu stri... by Dorin Joachim Mmasi, Dorin Joachim Mmasi, Prisca Kweyamba, Prisca Kweyamba, Prisca Kweyamba, Fatuma Matwewe, Masudi Suleiman Maasayi, Nolvin J. Mvungi, Nolvin J. Mvungi, Ummi Abdul Kibondo, Tibebu Habtewold, Tibebu Habtewold, Jennifer C. Stevenson, Jennifer C. Stevenson, Jennifer C. Stevenson, Lorenz Martin Hofer, Lorenz Martin Hofer, Lorenz Martin Hofer, Sarah Jane Moore, Sarah Jane Moore, Sarah Jane Moore, Sarah Jane Moore, Mgeni M. Tambwe, Mgeni M. Tambwe

“…This study aimed at optimizing DMFA through assessing the following 1) artemether–lumefantrine treatment 2) mosquito feeding time and 3) serum replacement on gametocyte infectiousness to mosquitoes in a low malaria transmission settingMethodsSix gametocytemic carriers were found to be eligible, from whom 4 mL of venous blood was drawn. …”
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Optimal Management in the Operation of Complex Technical Systems by Dyadyura K., Oborskyi G., Prokopovych I., Khamitov V., Holubiev M.

“…It was also shown how to optimize maintenance decisions for these systems in terms of the minimum average unit cost and how reliable this ensures. …”
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What proportion of people have long-term pain after total hip or knee replacement? An update of a systematic review and meta-analysis by Rachael Gooberman-Hill, Michael R Whitehouse, Hung-Yuan Cheng, Andrew David Beswick, Vikki Wylde, Wendy Bertram, Mohammad Ammar Siddiqui

“…Objectives To update our previous systematic review to synthesise latest data on the prevalence of long-term pain in patients who underwent total hip replacement (THR) or total knee replacement (TKR). We aim to describe the prevalence estimates and trends in this review.Design Systematic review and meta-analysis.Data sources Update searches were conducted in MEDLINE and Embase databases from 1 January 2011 to 17 February 2024. …”
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Optimal Simultaneous Approximation via 𝒜-Summability by Francisco Aguilera, Daniel Cárdenas-Morales, Pedro Garrancho

“…We present optimal convergence results for the mth derivative of a function by sequences of linear operators. …”
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Approximating optimization problems in graphs with locational uncertainty by Marin Bougeret, Jérémy Omer, Michael Poss

“…Many combinatorial optimization problems can be formulated as the search for a subgraph that satisfies certain properties and minimizes the total weight. …”
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Prosthesis survival situation and complications following total hip arthroplasty in hemophilic patients: a systematic review by Lei Chen, Shineng Lin, Wenlu Zhou, Yiqing Ling, Zhenyu Shi, Qinwen Ge, Wenbin Liu, Ju Li, Peijian Tong, Huihui Li, Taotao Xu

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Effect of Irrigation Interval and Corn (Zea mays L.)-Sorghum (Sorghum bicolor L.) Intercropping on the Quantitative and Qualitative Characteristics of Fodder by Saeed Sadeghzadeh Hemayati, Hamed Mansouri, Mohsen Shahsavarpour

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Study on the synergistic extinguishing effect of perfluorohexanone-nitrogen by Kai Wang, Dezheng Wang, Biao Zhou, Xuyao Wang, Tao Chen

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A Comparative Analysis of Functional Outcomes between Lateral and Posterolateral Approaches in Total Hip Arthroplasty by Farzad Amouzadeh Omrani, Sina Afzal, Mojtaba Baroutkoub, Sohrab Salimi, Hasan Barati, Sina Azadnajafabad, Saeed Kokly, Mohammad Mehdi Omidian

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A Rare Case of Lateral Femoral Condyle Osteonecrosis of Knee in a Young Patient Treated with Robotic Total Knee Replacement: A Case Report by K T Rajashekhar, Kartik Mangsuli, Adarsh Krishna K Bhat

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Mejora en la detección, diagnóstico y tratamiento temprano de la enfermedad renal crónica en España. Proyecto IntERKit by José Luis Górriz, Fran Adán Gil, Manuel A. Botana López, Antonio Buño Soto, Francisco José Campos Cabrera, Angeles Cisneros, Silvia Cobo Guerrero, María Dolores Conejos, Isabel Egocheaga Cabello, M. Concepción Fernández Planelles, Lisardo García-Matarín, Natalia Jiménez, Juan Carlos Julián Mauro, David León Jiménez, Daniel Martínez Gamote, Pilar Mazón Ramos, Alberto Ortiz, Gemma Palau, Julia Quevedo Rivera, J. Emilio Sánchez-Álvarez, Rita Tristancho Ajamil, Cristina Varga Martín, Roser Vallés Fernández

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Five-Year Sales Trends of Osteoporosis Medications in Korea: A Market Analysis Based on IMS Health Sales Audit Data (2018–2023) by Jung Yoon Park, Youn-Jee Chung, Mee-Ran Kim, Jae-Yen Song

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Clinical factors associated with severe coronary stenosis in patients undergoing cardiac surgery by Rui Wang, Wei Gao, Xinyu Che, Ruopei Shen, Chunfeng Dai, Yan Xia, Ao Chen, Danbo Lu, Jiaqi Ma, Hungju Chen, Chenguang Li, Zhangwei Chen, Juying Qian, Junbo Ge

“…Methods A retrospective cohort study was conducted on 5,086 patients who underwent valve repair/replacement or other cardiac surgeries at Zhongshan Hospital between 2016 and 2021 and received CAG. …”
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Exploring target selectivity in designing and identifying PI3Kα inhibitors for triple negative breast cancer with fragment-based and bioisosteric replacement approach by Debojyoti Halder, Shreya Mukherjee, R. S. Jeyaprakash

“…After extensive literature analysis, it was observed that fragment-based drug discovery, combined with structure-based virtual screening and bioisosteric replacement strategy, could provide a novel way for hit-to-lead optimization. …”
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Hybridization of Galactic Swarm and Evolution Whale Optimization for Global Search Problem by Binh Minh Nguyen, Trung Tran, Thieu Nguyen, Giang Nguyen

“…Concretely, the exploitation phase of Galactic Swarm Optimization is replaced by our Evolution Whale Optimization Algorithm to avoid early convergence. …”
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Use of testosterone replacement therapy in the rehabilitation of patients with intensive care unit-associated weakness and hospital-associated deconditioning: the Singapore General... by Geoffrey Sithamparapillai Samuel, Du Soon Swee

“…A multidisciplinary approach would ensure that suitable patients benefit from optimal nutrition, optimal rehabilitation and synergistic testosterone therapy in a clinically sound and resource-efficient fashion.…”
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Tricuspid Valve Replacement, Permanent Pacemaker Insertion, and Orthotopic Liver Transplantation in a Patient with Decompensated Chronic Liver Disease Complicated by Severe Tricusp... by Anuhya Rambhatla, G. V. Prem Kumar, Shakti Swaroop, Govindu Banoth, Sindhuja Kayati, Balachandran Palat

“…A multidisciplinary approach was crucial in ensuring optimal preoperative care and successful outcomes.…”
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Experimental and numerical investigation of the axial performance of GFRP-strengthened concrete columns incorporating red mud and quarry dust as sustainable cement and fine aggrega... by Pradeep Thangavel, Jabar Abdul Bari, Divesh Ranjan Kumar, Warit Wipulanusat, Jeung-Hwan Doh

“…The results demonstrated that combining RM and QD produced optimal performance for concrete structures. The combination of 10 % RM as cement replacement and 60 % QD as acceptable aggregate replacement resulted in a notable compressive strength of 33.12 MPa, confirming structural viability. …”
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Characteristics and Efficacy of Warfarin Sodium Tablet Subdivided by 3D Printing Technology: A Retrospective Cohort Study of Patients After Prosthetic Valve Replacement by Lv J, Fu K, Xiong L, Chen B, Zhan L, Liu J, Lin Z, Yang F, Chen J

“…Jieqiong Lv,1 Kaixia Fu,2 Lingjuan Xiong,3 Bishan Chen,4 Luchuan Zhan,3 Jiang Liu,3 Zhanyi Lin,5 Fan Yang,2,4 Jisheng Chen4 1Department of Pharmacy, The Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, People’s Republic of China; 2Guangdong Provincial Key Laboratory of Advanced Drug Delivery Systems and Guangdong Provincial Engineering Center of Topical Precise Drug Delivery System, Teaching Laboratory Center, Guangdong Pharmaceutical University, Guangzhou, Guangdong, People’s Republic of China; 3Department of Pharmacy, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 4Key Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, Guangdong, People’s Republic of China; 5Guangdong Geriatric Institute, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, People’s Republic of ChinaCorrespondence: Fan Yang, Email gzyangfan@hotmail.com Jisheng Chen, Email cjslym@163.comBackground: Due to the individual-level clinical variation in dosing requirements in commercially available drugs, attaining the objective of clinical individualization and precise drug administration continues to pose a global challenge. Currently, the optimal approach for preparing personalized and precise medications within the clinical setting is unknown.Aim: This study aimed to explore the effectiveness, safety and satisfaction of three-dimensional (3D) printing technology as a novel subdivision method in providing precise warfarin sodium (WFS) subdivided tablets for patients after prosthetic valve replacement (PVR).Methods: The optimal formulation, preparation process, parameters, and the relationship between dose and the printing volume were investigated, and the quality of the six specifications of WFS 3D-printed subdivided and pharmacist-split tablets was studied. …”
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Effects of Partial Replacement of Cement with Fly Ash on the Mechanical Properties of Fiber-Reinforced Rubberized Concrete Containing Waste Tyre Rubber and Macro-Synthetic Fibers by Mizan Ahmed, Nusrat Jahan Mim, Wahidul Biswas, Faiz Shaikh, Xihong Zhang, Vipulkumar Ishvarbhai Patel

“…The inclusion of MSF effectively mitigated strength loss induced by rubber aggregates, improving post-cracking behavior and toughness. Overall, an optimal balance was achieved at 25% fly ash replacement combined with 10% rubber and 0.5% fiber content, producing a more sustainable composite with favorable mechanical properties while reducing carbon and ecological footprints. …”
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