A Polysorbate-Based Lipid Nanoparticle Vaccine Formulation Induces In Vivo Immune Response Against SARS-CoV-2 by Aishwarya Saraswat, Alireza Nomani, Lin-Kin Yong, Jimmy Chun-Tien Kuo, Heather Brown, Muralikrishna Narayanareddygari, Avery Peace, Rizan Fazily, Timothy Blake, Christopher D. Petro, Bindhu Rayaprolu, Johanna Hansen, Amardeep Singh Bhalla, Mohammed Shameem

“…<b>Methods</b>: We employed a stepwise optimization to establish both the lipid composition and formulation buffer to yield a stable, high-performing PS-80-based SARS-CoV-2 mRNA-LNP (SC2-PS80 LNP). …”
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U-Net-based VGG19 model for improved facial expression recognition by Xiaohu ZHAO, Jingyi ZHANG, Mingzhi JIAO, Lixun XIE, Lanfei WANG, Weiqing SUN, Di ZHANG

“…The innovation of the SEAttention module lies in replacing the original activation function with the Mish activation function, which can dynamically adjust the weights of different channels to enhance performance. …”
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What can we learn about tropospheric OH from satellite observations of methane? by E. Penn, D. J. Jacob, Z. Chen, J. D. East, M. P. Sulprizio, L. Bruhwiler, J. D. Maasakkers, H. Nesser, Z. Qu, Y. Zhang, J. Worden

“…Here we combine SWIR and TIR satellite observations from the GOSAT and AIRS instruments, respectively, in a 3-year (2013–2015) analytical Bayesian inversion optimizing both methane emissions and OH concentrations. …”
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Research Progress on Selective Depolymerization of Waste Plastics to High-Quality Liquid Fuels by Xinze LI, Zhicheng LUO, Rui XIAO

“…To address these challenges, three actionable pathways are proposed: (1) Pilot-scale optimization: Current studies predominantly use lab-scale feeds (<100 g), necessitating trials with industrial-grade plastics containing pigments and plasticizers. …”
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Lightweight Apple Leaf Disease Detection Algorithm Based on Improved YOLOv8 by LUO Youlu, PAN Yonghao, XIA Shunxing, TAO Youzhi

“…SPD-Conv was introduced to replace the original convolutional layers to retain fine-grained information and reduce model parameters and computational costs, thereby improving the accuracy of disease detection. …”
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Registro Español de Enfermos Renales (REER): informe del año 2022 y análisis evolutivo by Borja Quiroga, Beatriz Mahíllo, Auxiliadora Mazuecos, Alberto Ortiz, Jordi Comas Farnés, Domingo Hernández Marrero, Sara Trujillo Alemán, M. Carmen Santiuste de Pablos, Olga Lucía Rodríguez Arévalo, María Marques Vidas, M. Fernanda Slon-Roblero, Marta Artamendi Larrañaga, Iñigo Moina Eguren, María de la Oliva Valentín Muñoz, Marta Rodríguez Camblor, Inmaculada Moreno Alia, M. Encarnación Bouzas Caamaño, M. Antonia Blanco Galán, Javier Deira Lorenzo, Héctor García López, Federico Eduardo Arribas Monzon, Gonzalo Gómez Marqués, Alberto Rodríguez-Benot, Beatriz Domínguez-Gil, Emilio Sánchez Álvarez

“…Additional measures must be adopted to harmonize and optimize kidney health care.…”
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AGW-YOLO-Based UAV Remote Sensing Approach for Monitoring Levee Cracks by HU Weibo, ZHOU Shaoliang, ZHAO Erfeng, ZHAO Xueqiang

“…Finally, to address the multi-scale variation of cracks, the original loss function was replaced with WIoUv3. This loss function incorporates an outlier degree evaluation and a dynamic non-monotonic focusing mechanism, which adaptively adjusts the optimization intensity of anchor boxes with varying qualities. …”
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芝麻香油水代法连续化生产新工艺研究A new continuous production process of fragrant sesame seed oil by aqueous extraction method by 宋国辉，孙强，游静，张勋，李可心，芦鑫，黄纪念SONG Guohui, SUN Qiang, YOU Jing, ZHANG Xun, LI Kexin, LU Xin, HUANG Jinian

“…On the basis of examining the feasibility of centrifugation and determining the basic conditions for simulation continuous centrifugation, the parameters of grinding and water adding and mixing process were optimized, and the optimized process was verified by three-phase horizontal screw centrifuge in the actual production. …”
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Management and Operation Transformation of Urban Park Green Spaces from the Perspectives of Public Goods Provision and Fiscal Sustainability by Peiyi JIA

“…Modernizing policy frameworks to accommodate regional disparities and allowing selective revenue-generation strategies may balance ecological mandates with fiscal realities. Crucially, replacing output-based metrics with outcome-oriented indicators measuring health impacts and social cohesion could realign incentives with public value creation. …”
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HyperCell: A Bio-inspired Design Framework for Real-time Interactive Architectures by Jia-Rey Chang

“…This involves a detailed study/critique of organic architecture, generating organic shapes, performance optimization based digital fabrication techniques and kinetic systems. …”
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Synergistic Effect of Nitrogen Fertilizer Management on Rice Productivity and Quality by Yongkang Teng, Rongjie Chen, Meng Guo, Xianguan Chen, Min Jiang

“…But the two varieties can ensure optimal quality under yield conditions by reducing panicle fertilizer application by 50% and replacing chemical fertilizers with compound fertilizers.…”
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Formation of a Strategy for Increasing the Efficiency of Operation of Distribution Electrical Grids at the Stage of Pre-Design Works by A. V. Zhurakhivskyi, Z. M. Bakhor, A. Ya. Yatseiko, V. H. Hapanovych

“…On the basis of this model an algorithm for a choice of the optimal technical measures for the reconstruction of mainlines has been formed depending on their state: for mainlines in the strenuous state it is possible to replace the wire of the section or an installation of a battery of statistical capacitors at the remote transformer substations; for mainlines in the unacceptable state, in accordance with the results of an expert assessment of possible measures taking into account the electrical grid development, the prospects of increase of the load, the construction of unloading points, the connection to the distributed generation electrical grid, a decision is being made to replace the wire section, to transform a part or the whole electrical grid to higher voltage level. …”
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Locally Enhanced Flow and Electric Fields Through a Tip Effect for Efficient Flow-Electrode Capacitive Deionization by Ziquan Wang, Xiangfeng Chen, Yuan Zhang, Jie Ma, Zhiqun Lin, Amor Abdelkader, Maria-Magdalena Titirici, Libo Deng

“…Highlights Steel tip arrays were used as current collectors to replace planar conductors. Optimal flow and electric fields reduced barriers for electron and ion transport. …”
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The Effects of Using Eco-friendly Materials for the Production of High Strength Mortar by Mohammad Faisal Khalil, Eethar Thanon Dawood

“… This study aims to evaluate the effect of using eco-friendly mineral admixtures, such as calcined clay (CC), silica fume (SF), and limestone (L), as partial replacements for ordinary Portland cement (OPC) in the production of high-strength mortar(HSM). …”
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Design and analysis of active disturbance rejection and field weakening control system for PMSM based on FCS-MPC by YU Yuting, HUANG Jie, CHU Yanting, ZHOU Fangyuan

“…To mitigate torque term interferences, this paper presents a combination of finite control set model predictive control (FCS-MPC) and a model predictive torque control system based on torque and flux linkage output design, to replace traditional direct torque control (DTC). Based on a value function constructed to minimize torque and flux linkage ripples, calculations and optimizations enable the selection of optimal space vector control signals that are then transmitted to the inverters. …”
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High accuracy identification of maize seed varieties based on a lightweight improved YOLOv8 by Siqi Niu, Xiaolin Xu, Ao Liang, Yuliang Yun, Fengqi Hao, Jinqiang Bai, Wenyi Sheng, Dexin Ma

“…Additionally, the Detect module was replaced with the improved Detect_EMA module, which efficiently retained information in each channel, reduced computational load, and more specifically optimized detection results. …”
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Co-Combustion of Tire Pyrolysis Products and Wood Pellets by A. V. Grytsenko, N. V. Vnykova, O. I. Pozdnyakova

“…At the same time, the following tasks have been set: to determine the lowest combustion heat of mixed fuels and assess its change when replacing coal with slag; to determine moisture content, total sulfur content, volatile matter yield, ash content of mixed fuels according to standard methods; to assess the change in these parameters when replacing coal with slag at the same component ratios; to determine the optimal ratios of components in mixed fuels, which will not increase the burden on the environment when replacing coal with pyrolysis slag. …”
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Engineering Lipid–Polymer Nanoparticles for siRNA Delivery to Cancer Cells by Arthur Manda, Abdulelah Alhazza, Hasan Uludağ, Hamidreza Montazeri Aliabadi

“…Leveraging the optimal LNP formulation, we integrated specifically designed cationic polymers as partial or complete replacements for the ionizable lipid. …”
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Excellent comprehensive piezoelectric performances of SiC-doped BCTZ-based lead-free piezoelectric ceramics by Aihui Yang, Yu Huan, Qingying Wang, Ting Wang, Yuanhui Su, Tao Wei

“…With increasing awareness of environmental protection, the electrical performance and sintering process of lead-free piezoelectric ceramics are continuously optimized to replace lead-based materials. Exploring an appropriate doping strategy is believed to achieve concurrent improvements in lead-free piezoelectric ceramics. …”
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ILIZAROV’S TRANSBONE COMPRESSION-DISTRACTION OCTEOSYNTHESIS FOR PATIENTS WITH PRIMARY CANCER OF LOWER EXTREMITIES by P. I. Balaev, D. Yu. Borzunov

“…The Ilizarov’s transbone ostheosynthesis allows the defects after resection to be effectively replaced with optimal reconstruction of the extremity both in adult patients and in patients with incomplete formation of the skeleton.…”
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