A method to assess target gene involvement in angiogenesis in vitro and in vivo using lentiviral vectors expressing shRNA. by Wayne Blosser, Eliza Vakana, Lisa V Wyss, Michelle L Swearingen, Julie Stewart, Louis Stancato, Courtney M Tate

“…Here, we utilized an in vitro adipocyte derived stem cell and endothelial colony forming cell (ADSC/ECFC) co-culture system to investigate the effect of lentiviral-driven shRNA knockdown of target genes compared to a non-targeting shRNA control on cord formation using High Content Imaging. …”
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RETRACTED: In Vivo Clearance of Apoptotic Debris From Tumor Xenografts Exposed to Chemically Modified Tetrac: Is There a Role for Thyroid Hormone Analogues in Efferocytosis? by Kavitha Godugu, Shaker A. Mousa, Gennadi V. Glinsky, Hung-Yun Lin, Hung-Yun Lin, Hung-Yun Lin, Paul J. Davis, Paul J. Davis

“…Tetrac also enhances transcription of chemokine CXCR4, which is relevant to macrophage function. Tetrac may locally control the conformation of phagocyte plasma membrane integrin αvβ3; this is a cell surface recognition system for apoptotic debris that contains phagocytosis signals. …”
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Cerebrovascular complication of infective endocarditis complicated with abdominal trauma by Başak Akyıldız, Nazan Ülgen-Tekerek, Abdullah Özyurt, Özge Pamukçu, Nazmi Narin

“…There was no evidence of a perivalvular abscess. On control transthoracic echocardiography, after 6 weeks of parenteral antibiotic treatment, there was no significant reduction of the visible vegetation therefore surgery was planned. …”
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Astaxanthin mitigates diabetic cardiomyopathy and nephropathy in HF/HFr/STZ diabetic rats via modulating NOX4, fractalkine, Nrf2, and AP-1 pathways by Nesma M.E. Abo El-Nasr, Yosra A. Hussien, Marawan Abd El-Baset, Marwa E. Shabana, Dalia O. Saleh

“…Diabetic control rats exhibited significant impairment in renal and cardiac functions, heightened oxidative stress, and altered ECG parameters. …”
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Secondary stroke prevention beyond antiplatelets: The role of colchicine and GLP-1RA – an ounce of prevention is worth a pound of cure by Milija D. Mijajlović, Natan M. Bornstein, Vuk Aleksić

“…These agents enhance glucose control while also providing protective effects against atherosclerosis and stroke. …”
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Diagnostical significance of dimethylarginine in the development of hepatorenal syndrome in patients with alcoholic liver cirrhosis by Ničković Vanja, Nikolić Jelenka, Đinđić Nataša, Ilić Мilena, Ničković Jovan, Mladenović Dragan, Krstić Nebojša

“…Chronic consumption of alcohol during a longer period of time leads to the development of cirrhosis with the reduction in metabolic liver function and disorders in arginine metabolism. …”
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Effect of conditioned medium from miRNA-34a transfected gastric cancer-associated fibroblast on peripheral blood mononuclear cells by Mozhgan Esmaili, Narjes Jafari, Fatemeh Ahmadzadeh, Seyed Mohammad Valizadeh Toosi, Saeid Abediankenari

“…Therefore, this study aimed to evaluate the function of miRNA34a in CAF cells in gastric carcinoma. …”
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The novel long noncoding RNA linc00467 promotes cell survival but is down-regulated by N-Myc. by Bernard Atmadibrata, Pei Y Liu, Nicolas Sokolowski, Lihong Zhang, Matthew Wong, Andrew E Tee, Glenn M Marshall, Tao Liu

“…Here we performed differential gene expression studies using lncRNA microarray in neuroblastoma cells after transfection with control or N-Myc-specific small interfering RNA (siRNA), and identified N-Myc target lncRNAs including the novel lncRNA linc00467, the expression and function of which were completely unknown. …”
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Phase 1 clinical trial of eneboparatide, a novel PTH receptor 1 agonist by Michel Ovize, Soraya Allas, Michael D Culler, Stephane Milano, Taha Ouldrouis, Mark Sumeray, Jeroen van de Wetering de Rooij, Michael Mannstadt

“…Design: This was a randomized, double-blind, placebo-controlled study. One-hundred four healthy volunteers were recruited into seven single ascending dose (SAD) and five multiple ascending dose (MAD) cohorts. …”
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The Expression and Regulatory Role of lncRNA CRNDE in Ischemic Stroke by Yuan Cheng, Qiujun Lu, Yuanyuan Su, Runxi Xu, Shuqi Huang, Chong Yang, Yunhua Hao, Jun Yang

“…Objective This study focused on investigating the function of lncRNA CRNDE in IS. Materials and Methods 237 participants were enrolled in this study, including 135 patients with ischemic stroke (Ischemic stroke group) and 102 healthy individuals (Control group). …”
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Screening Coverage Needed to Reduce Mortality from Prostate Cancer: A Living Systematic Review. by Ahmad K Rahal, Robert G Badgett, Richard M Hoffman

“…<h4>Methods</h4>We performed a living systematic review and meta-regression of the reduction in prostate cancer mortality as a function of the duration of screening provided in each trial. …”
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High-salt–fat diet: a risk factor for elevated blood pressure associated with dyslipidemia, perturbation in cardio-renal anti-oxidant and pro-inflammatory status in Wistar rats by Olumide Samuel Fadahunsi, Olubukola Sinbad Olorunnisola

“…This study sought to evaluate the role of high-salt–fat diet (HS-HFD) on blood pressure (BP), cardio-renal function, redox and inflammatory status. Twelve male Wistar rats were divided into two groups and fed with normal chow and HS-HFD, respectively. …”
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Separable roles of the DNA damage response kinase Mec1ATR and its activator Rad24RAD17 during meiotic recombination. by Margaret R Crawford, Jon A Harper, Tim J Cooper, Marie-Claude Marsolier-Kergoat, Bertrand Llorente, Matthew J Neale

“…By contrast, loss of Mec1 function increases recombination frequency, consistent with its role in DSB trans-interference, and has less effect on spore viability. …”
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Mechanical and Physical Performance of Cement Paste Containing Olive Waste Ash: Implications for Paving Block Applications by Safa Ghazzawi, Hassan Ghanem, Safwan Chahal, Jamal Khatib, Adel Elkordi

“…At 90 days, the compressive strength of the control cement paste is 50 MPa, whereas the 10% OWA mixture exhibits a value of 46 MPa, corresponding to only an 8% reduction. …”
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Sunflower-based butterfly optimization algorithm with enhanced RNN for the harmonics elimination in multilevel inverter by V. Mohan, G. Krithiga, M. Thamil Alagan, V. Sathya

“…SF-BOA’s optimized switching angle is used for 11-level three-phase PWM control using the Cascaded H Bridge architecture for harmonic reduction of the entire modulation index. …”
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Isomorphism-Based Fast Simulation of Mismatched Photovoltaic Arrays by D. del Giudice, A. Dolara, J. D. Bastidas-Rodriguez, G. Spagnuolo, A. M. Brambilla, F. Bizzarri

“…The application examples proposed in the article, concerning a PV array affected by a partial shading by nearby objects that changes during the day and a faulty PV field made up of half-cut modules, allow one to quantify the reduction in model complexity and the consequent computation time granted by the proposed technique as a function of the desired accuracy of the simulation results.…”
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Curcumin reduces pain after spinal cord injury in rats by decreasing oxidative stress and increasing GABAA receptor and GAD65 levels by Maryam Hadadi, Mohammad Mojtaba Farazi, Mehrnaz Mehrabani, Mahsa Tashakori-Miyanroudi, Zahra Behroozi

“…Motor function, allodynia, and hyperalgesia were assessed using the BBB scale, acetone, and tail-flick until six weeks after SCI. …”
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Incidence, complications and therapeutic evaluation of clinical hypothyroidism in different breeds of dogs by Gehad E. Elgalfy, Mohamed M. Ghanem, Mahmoud A. Y. Helal, Heba M. El-khaiat

“…Method Total number of 212 dogs of different ages, breeds and of both sexes were included in this study, where 200 dogs were suffering from alopecia or obesity, the other 12 healthy dogs were used as control group. Results After ruling out other causes of alopecia and obesity, hypothyroidism was diagnosed in 28 dogs (14%) depending on the result of thyroid function test. …”
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Neuromuscular diseases and social distance resulting from the COVID-19 pandemic by Flaviana Kelly de Lima Maciel, Luis Fernando Grossklauss, Francis Meire Favero, Cristina dos Santos Cardoso de Sá

“…Results We observed a significant reduction in medical appointments for patients with NMDs. …”
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Preparation and Therapeutic Evaluation of Engineered Semaglutide and Statin–Lipid Conjugate-Based Nanoparticle by Kyeong-Ju Lee, Seong-Bin Yang, Jae-Hyeon Lee, Bison Seo, Hyung-Sik Won, Jooho Park

“…In animal experiments, the treatment group demonstrated a 30.24% reduction in body weight and a 46.80% improvement in liver function markers compared to the control group. …”
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