Myocardial Infarction Injury Is Exacerbated by Nicotine in Vape Aerosol Exposure by Clarissa Savko, Carolina Esquer, Claudia Molinaro, Sophie Rokaw, Abraham G. Shain, Faid Jaafar, Morgan K. Wright, Joy A. Phillips, Tyler Hopkins, Sama Mikhail, Abigail Rieder, Ariana Mardani, Barbara Bailey, Mark A. Sussman

“…Comparable loss of contractile function was not observed in mice exposed to vape aerosol alone, highlighting the essential role of nicotine in loss of contractile function. …”
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Mild intermittent hypoxia may improve autonomic dysfunction in persons living with spinal cord injury: a preliminary snapshot by Alexandra E. Soltesz, Alexandra E. Soltesz, Fei Zhao, Fei Zhao, Jill M. Wecht, Jill M. Wecht, Jason H. Mateika, Jason H. Mateika, Jason H. Mateika, Gino S. Panza, Gino S. Panza, Gino S. Panza

“…One potential intervention is daily mild intermittent hypoxia (MIH) which has been shown to improve blood pressure control and upper airway function during sleep. Four individuals with chronic motor incomplete SCI underwent 8 days of MIH (ClinicalTrials.Gov ID #NCT05351827, https://clinicaltrials.gov/study/NCT05351827). …”
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Influenza A virus N-linked glycosylation sites with very low glycan occupancy: identification, evolutionary dynamics, and impact on virus biology by Dr Irina Alymova, Dr Wen-Pin Tzeng, Dr Alexander Jureka, Dr John Barr, Dr Dongxia Wang, Dr Betlehem Mekonnen, Mr Shane Gansebom, Dr Ian York

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Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques. by Rachele M Bochart, Kathleen Busman-Sahay, Stephen Bondoc, David W Morrow, Alexandra M Ortiz, Christine M Fennessey, Miranda B Fischer, Oriene Shiel, Tonya Swanson, Christine M Shriver-Munsch, Hugh B Crank, Kimberly M Armantrout, Aaron M Barber-Axthelm, Charlotte Langner, Cassandra R Moats, Caralyn S Labriola, Rhonda MacAllister, Michael K Axthelm, Jason M Brenchley, Brandon F Keele, Jacob D Estes, Scott G Hansen, Jeremy V Smedley

“…Reduction in and increased consistency of number of transmitted founder variants resulting from challenge seen in the proof of concept study directly correlated with post-treatment GPF animal's improved barrier function and reduction of key target cell populations (Ki-67+ CD4+T cells) at the site of viral acquisition in the follow up study. …”
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Harnessing phage consortia to mitigate the soil antibiotic resistome by targeting keystone taxa Streptomyces by Hanpeng Liao, Chang Wen, Dan Huang, Chen Liu, Tian Gao, Qiyao Du, Qiu-e Yang, Ling Jin, Feng Ju, Mengting Maggie Yuan, Xiang Tang, Pingfeng Yu, Shungui Zhou, Pedro J. Alvarez, Ville-Petri Friman

“…Conclusion Our study demonstrates that some bacterial keystone taxa are critical for ARG maintenance and dissemination in soil microbiomes, and opens new ecological avenues for microbiome modification and resistome control. This study advances our understanding of how metagenomics-informed phage consortia can be used to predictably regulate soil microbiome composition and functioning by targeting keystone bacterial taxa. …”
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THE EFFECTS OF AEROBICS AND SOY MILK ON TRIGLYCERIDES AND MENOPAUSAL SYMPTOMS by Dhea Novita, Rr Sri Endang Pujiastuti, M Choiroel Anwar, Septiwiyarsi

“…This research was a Quasi-Experiment with a pretest-posttest design with a control group. The result shows that low-impact aerobic exercise and soy milk have an effect on reducing triglyceride levels with a p-value of 0.000 <0.05 and a mean delta reduction of 72.0. …”
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Drip irrigation in coffee crop under different planting densities: Growth and yield in southeastern Brazil by Gleice A. de Assis, Myriane S. Scalco, Rubens J. Guimarães, Alberto Colombo, Anderson W. Dominghetti, Nagla M. S. de Matos

“…Irrigation associated to reduction on planting spaces between rows and between coffee plants has been a featured practice in coffee cultivation. …”
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Evaluation of posterior segment changes in pediatric asthma patients with and without inhaled corticosteroid therapy by Ulviye Kıvrak, Fatih Çiçek, Mehmet Tolga Köle, Büşra Kaya Adaş, İbrahim Kandemir

“…Asthma patients demonstrated a statistically significant reduction in subfoveal choroidal thickness, the superficial capillary plexus in the superior and nasal quadrants, the choriocapillaris in the foveal quadrant, and the peripapillary vascular density in the inferior and superior quadrants compared to controls. …”
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Cardiac specific knock-down of peroxisome proliferator activated receptor α prevents fasting-induced cardiac lipid accumulation and reduces perilipin 2. by Natasha Fillmore, Natasha Fillmore, Vincent Hou, Junhui Sun, Danielle Springer, Elizabeth Murphy

“…After fasting, cPPAR-/- mice had dramatically lower cardiac triglyceride levels than control mice. Interestingly, cPPAR-/- hearts also had reduced Plin2, a key protein involved in lipid accumulation and lipid droplet regulation, which may contribute to the reduction in cardiac lipid accumulation. …”
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Coactivator-associated arginine methyltransferase 1 promotes cell growth and is targeted by microRNA-195-5p in human colorectal cancer by Meifeng Zhang, Wei Wu, Ming Gao, Jie Zhang, Xinde Ding, Ronghua Zhu, Haiqun Chen, Zhewei Fei

“…These data confirm that microRNA-195-5p might function as an anti-tumor microRNA in colorectal cancer exerting critical control over coactivator-associated arginine methyltransferase 1 expression. …”
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A Novel Voltage–Current Characteristic Model for Understanding of Electric Arc Furnace Behavior Using Experimental Data and Grey Wolf Optimization Algorithm by Mustafa Şeker, Emre Ünsal, Ahmet Aksoz, Mahir Dursun

“…The control of nonlinear systems cannot be effectively achieved using linear mathematical methods. …”
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The putative protein methyltransferase LAE1 of Trichoderma atroviride is a key regulator of asexual development and mycoparasitism. by Razieh Karimi Aghcheh, Irina S Druzhinina, Christian P Kubicek

“…In Ascomycota the protein methyltransferase LaeA is a global regulator that affects the expression of secondary metabolite gene clusters, and controls sexual and asexual development. The common mycoparasitic fungus Trichoderma atroviride is one of the most widely studied agents of biological control of plant-pathogenic fungi that also serves as a model for the research on regulation of asexual sporulation (conidiation) by environmental stimuli such as light and/or mechanical injury. …”
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Sex-specific effects of appetite suppressants on stereotypy in rats. by Axl Lopez, Elvi Gil-Lievana, Ranier Gutierrez

“…Phentermine and mazindol induced comparable weight loss in both sexes, whereas cathine elicited weight reduction exclusively in males. 5-HTP and d-amphetamine administration only prevented weight gain relative to controls. …”
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Determination of Cystatin C Level in a Sample of Patients with Chronic Kidney Disease by Maryam Noman Salman, Ashwak Jasim kzar, Alaa S. Hamzah

“…The purpose of this research was to examine the efficacy of cystatin C as a measure of renal function in individuals. Cystatin C, Creatinine, urea, and uric acid levels were measured in 225 blood samples (150 patients and 75 controls). …”
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A novel method for asynchronous source localisation based on time of arrival measurements by Huijie Zhu, Sheng Liu, Zhiqiang Yao, Moses Chukwuka Okonkwo, Zheng Peng

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SS-31: A promising therapeutic agent against bleomycin-induced pulmonary fibrosis in Mice. by Quankuan Gu, Yunlong Wang, Haichao Zhang, Wei Yang, Xianglin Meng, Mingyan Zhao

“…Electron microscopy and ATP detection further suggested that SS-31 might help protect mitochondrial structure and function. It was also found that SS-31 could reduce reactive oxygen species and myeloperoxidase, thereby alleviating the reduction of antioxidant factor MPO and SOD, as well as diminishing the inflammatory factors TNF-α, IL-1 β, and IL-6.…”
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Listeria monocytogenes infection in intestinal epithelial Caco-2 cells with exposure to progesterone and estradiol-17beta. by Anna Marie Hugon, Thaddeus G Golos

“…There were no significant differences in bacterial replication when directly exposed to sex steroids, and Caco-2 cell epithelial barrier function was not impacted during culture with Lm. Addition of progesterone significantly reduced intracellular bacterial burden compared to estradiol 17-beta only and no hormone controls. …”
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Lysyl-tRNA synthetase orchestrates translation and hormone signaling during reproduction in Aedes aegypti mosquitoes by Shan Li, Xueli Wang, Haoran Lu, Alexander S. Raikhel, Zhen Zou

“…This study demonstrates the function of KARS in regulating reproduction during the gonadotrophic cycle, hence providing insights into the potential control of disease-transmitting mosquitoes.…”
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Hypomethylation of the LncRNA H19 promoter accelerates osteogenic differentiation of vascular smooth muscle cells by activating the Erk1/2 pathways by Taoxia Wang, Meijuan Cheng, Jingjing Jin, Yaling Bai, Dongxue Zhang, Shenglei Zhang, Jinsheng Xu

“…Results Compared with the control group, high phosphorus levels induced VSMC calcification, accompanied by increases in LncRNA H19 and the osteogenic marker Runx2 and reduction of the contractile phenotype marker SM22a. …”
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Submarine Cable Vibration Signal Recognition Based on Sparrow Search Algorithm Optimized Support Vector Machine by GUO Jiaxing, QIAN Junxia, LIU Rui, MA Hongjuan

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