Interaction study of the effects of environmental exposure and gene polymorphisms of inflammatory and immune-active factors on chronic obstructive pulmonary disease by Rui Wang, Yuanyuan Li, Yuting Jiang, Xiaona Liu, Hongqi Feng, Zhe Jiao, Bingyun Li, Chang Liu, Yuncheng Shen, Fang Chu, Chenpeng Zhu, Dianjun Sun, Wei Zhang

“…Methods In this community-based case–control study, 471 patients with COPD and 485 controls aged 40–76 years in Heilongjiang Province, China were included. …”
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Evaluation of the Efficiency of Alveolar Opening in Cardiosurgical Patients with Low Left Ventricular Ejection Fraction by Yu. G Zorina, V. V. Moroz, A. M Golubev, Yu. V. Nikiforov

“…Objective: to determine the optimum alveolar opening parameters for the improvement of postoperative pulmonary oxygenizing function in patients with a left ventricular ejection fraction (LVEF) of less or more than 40% after aortocoronary bypass surgery (ACBS). …”
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Avelumab in First Line Maintenance in Advanced Urothelial Carcinoma (aUC) in Elderly Patients: Efficacy, Tolerability, and Quality of Life in Real Life Setting by Rossella De Luca, Pasquale Vitale, Alessio Pepe, Roberta Spedaliere, Alchiede Simonato, Raffaele Addeo, Giuseppe Cicero

“…Avelumab was well tolerated and resulted in good disease control, with a moderate toxicity profile and significant clinical benefit. …”
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Insulin secretion deficits in a Prader-Willi syndrome β-cell model are associated with a concerted downregulation of multiple endoplasmic reticulum chaperones. by Erik A Koppes, Marie A Johnson, James J Moresco, Patrizia Luppi, Dale W Lewis, Donna B Stolz, Jolene K Diedrich, John R Yates, Ronald C Wek, Simon C Watkins, Susanne M Gollin, Hyun Jung Park, Peter Drain, Robert D Nicholls

“…To determine the collective roles of PWS genes in β-cell biology, we used genome-editing to generate isogenic, clonal INS-1 insulinoma lines having 3.16 Mb deletions of the silent, maternal- (control) and active, paternal-allele (PWS). PWS β-cells demonstrated a significant cell autonomous reduction in basal and glucose-stimulated insulin secretion. …”
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Optimizing energy and load management in island microgrids for enhancing resilience against resource interruptions by Majid Hosseina, Mahmoud Samiei Moghaddam, Amir Hassannia

“…The results demonstrate that the proposed framework achieves a 60% reduction in voltage deviation, an 81% decrease in energy losses, and an 86% reduction in CO₂ emissions, while ensuring zero load curtailment, even under severe outage conditions. …”
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Adaptation of mitochondrial bioenergetics to coenzyme Q deficiency in human endothelial cells after chronic exposure to bisphosphonates by Adrianna Budzinska, Lukasz Galganski, Krzysztof Wojcicki, Wieslawa Jarmuszkiewicz

“…This study examined the effects of chronic six-day exposure of human endothelial cells to N-BPs on mitochondrial bioenergetic functions, focusing on drug-induced mitochondrial CoQ (mtCoQ) deficiency. …”
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Efficacy and safety of dapagliflozin combined with Bailing Capsule in treatment of patients with diabetic kidney disease by SUI Yingying, ZHOU Quan, HAN Yafei, SUN Jialin, HAN Zhiwu

“…Results After 12 months of treatment, the combination group had a significantly better clinical outcome than the control group (Z=2.919,P<0.05); the combination group had reductions in the levels of fasting plasma glucose, 2 hour postprandial glucose, and HbA1c after treatment, with significantly greater reductions in these indicators compared with the control group (t=41.91-59.57,P<0.05). …”
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Antioxidant Properties and Microbiological Stability of Yogurt Enriched with Elderberry Extract by Oana-Elena Pascariu, Letícia M. Estevinho, Natália L. Seixas, Ioan Dopcea, Oana A. Boiu-Sicuia, Mihaela Geicu-Cristea, Florentina Israel-Roming

“…In the first experiment, a reduction of about 2.3 CFU/g was observed from day 0 to day 21 in samples with 0.1% and 0.2% EDB extract, while the control sample showed a reduction of 1.84 CFU/g. …”
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Effect of Cortexin administration on Kisspeptin and Spexin expression after testicular torsion by Ahmet Turk, Busra Zencirci, Tuba Ozcan–Metin, Ibrahim Bozgeyik, Abdullah Karadag, Seda Koçak

“… Kisspeptin–1 (KISS–1) and Spexin (SPX) are neuropeptides that play crucial roles in metabolism and sexual function, with their expression levels in tissues potentially influenced by antioxidant treatments. …”
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Diet-induced adipose tissue expansion is mitigated in mice with a targeted inactivation of mesoderm specific transcript (Mest). by Rea P Anunciado-Koza, Justin Manuel, Randall L Mynatt, Jingying Zhang, Leslie P Kozak, Robert A Koza

“…Since inactivation of Mest in mice has minimal additional effects aside from reduction of ATE, an intervention that mitigates MEST function in adipocytes is a plausible strategy to obviate obesity and type-2-diabetes.…”
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Evaluating the Efficacy of a Novel Multi-Component Feed Additive for Methane Mitigation and Performance Enhancement in Sheep by M. Jordana Rivero, Afsal A. Khan, Tersur T. Akpensuen, Paulo Meo-Filho, Simón Pérez-Márquez, Andy Jones

“…This study assessed the efficacy of a multi-component feed additive that combines medium-chain fatty acids (MCFAs), live yeast, plant-based agents, and Vitamin B, in reducing methane emissions, improving feed efficiency, and enhancing growth and immune function in sheep. Twenty crossbred castrated male sheep (52 ± 3.7 kg) were divided into control and treatment groups (n = 10 each), with the treatment group receiving grass pellets supplemented with the multi-component feed additive (20 g/day) for 71 days, including a 30-day acclimatisation period. …”
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Assessing the Efficiency of Reduced Positional Games in Soccer: A Multivariate Analysis of Technical and Tactical Indicators According to Different Playing Systems by Mostafa Errama, Mustapha Bassiri, Jafaar Atifi, Said Lotfi

“…The between-subjects factor “Group” comprises two levels (experimental teams and control teams), while the within-subjects factors “Match” (three successive matches) and “Playing system” (two tactical configurations: 1-3-2-1 system and 1-2-3-1 system) make it possible to examine variations in performance indicators as a function of the playing context. …”
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The Possible Role of Plant-Based Bars Consumption in CKD Geriatric Patients by Giulia Marrone, Silvia Urciuoli, Manuela Di Lauro, Kevin Cornali, Claudia Masci, Manfredi Tesauro, Pamela Vignolini, Annalisa Noce

“…<b>Results and Conclusions</b>: At the end of this study, the PBBs group, compared to the control group, showed an improvement in their body composition, detected by bioimpedance analysis and ultrasound examination, and in their cognitive function, revealed by mini-mental state examination. …”
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ZNF671 Silencing Affects Signaling Pathways in Head and Neck Cancer via Activation of Oncogenic Non-Coding RNAs by Kendra Smith, Rufa’i Umar Zubair, Richard V. Smith, Stelby Augustine, Nicholas F. Schlecht, Thomas J. Ow, Michael B. Prystowsky, Thomas J. Belbin

“…Over-expression of ZNF671 in UM-SCC-1 oral cancer cells resulted in a significant reduction in tumor cell mobility and invasion compared to the empty-vector control cells. …”
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Changes in Amplitude-integrated Electroencephalograms in Piglets During Selective Mild Head Cooling After Hypoxia-ischemia by Ji-Mei Wang, Guo-Fu Zhang, Wen-Hao Zhou, Ze-Dong Jiang, Xiao-Mei Shao

“…Amplitude-integrated electroencephalogram (aEEG) is a simplified, alternative means of monitoring cerebral function and may be more useful clinically in some situations than conventional EEG. …”
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The role of carbonate equilibrium in scale formation of calcium carbonate in a power plant open recirculating system by Pavlo Kuznietsov, Olha Biedunkova

“…The principal function of an open recirculating system (ORS) is to remove heat from power plant equipment. …”
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CHARACTERISTICS OF BLOOD RHEOLOGICAL PARAMETERS IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE by M. M. Egorova, O. A. Ovchinnikova, E. P. Petrochenko, A. O. Oslyakova, V. V. Yakusevich

“…Revealed significant changes in properties of the blood stream, which in turn led to a marked reduction in oxygen-function of the blood in 27.5 % (p &lt; 0.001).Conclusions. …”
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Evening primrose oil ameliorates tissue architecture, apoptosis, and oxidative stress in the pancreas of diabetic rats: Possible role of miR-21 by Ali Louei Monfared, Ali Menatnia

“…Treatment with EPO resulted in a reduction of miR-21 and caspase-3 expression, as well as MDA levels, and an increase in insulin expression and SOD levels compared to the diabetic group. …”
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Beneficial Role of Imeglimin as Add-on Drug with other Oral Hypoglycaemic Agents for Patients with Type 2 Diabetes: A Single centre Prospective Interventional Study by Naima Parveen, Sachin Chittawar

“…Introduction: With Type 2 Diabetes Mellitus (T2DM) affecting over 74 million individuals in India alone, achieving glycaemic control remains a persistent challenge, especially in patients inadequately managed with Oral Hypoglycaemic Agents (OHAs). …”
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Evaluation of the efficacy of supplementary probiotic capsules with topical clobetasol propionate 0.05% versus topical clobetasol propionate 0.05% in the treatment of oral lichen p... by Yasmine Kamal, Amira Abdelwhab, Sherifa Tarek Salem, Mariam Fakhr

“…Results Significant reduction in the numerical rating scale as well as Thongprasom scale in the probiotic group when compared to the control group, after 2 and 4 weeks, and more significant reduction was observed after 2 weeks. …”
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