Fault Detection and Identification for Nonlinear Process Based on Inertia-Based KEPCA and a New Combined Monitoring Index by Loubna El Fattahi, El Hassan Sbai

“…Second, it constructs the model. Before data reduction, KEPCA transforms input data into high-dimensional feature space based on a nonlinear kernel function and automatically determines the number of principal components (PCs) based on the computation of the inertia. …”
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Acute Immobilization Stress Modulate GABA Release from Rat Olfactory Bulb: Involvement of Endocannabinoids—Cannabinoids and Acute Stress Modulate GABA Release by Alejandra Delgado, Erica H. Jaffé

“…Inhibition of the endocannabinoid transport or its catabolism showed reduction of GABA release, antagonized by AM281 in control and stressed animals. …”
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Production of oxygen free radicals by Ehrlich ascites tumour cells: effect of lipids by Gopal K. Marathe, Cletus J. M. D'Souza

“…These results suggest that membrane lipids and dietary factors like vitamin A probably function as physiological modulators in regulating the free radical generation.…”
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The use of artificial intelligence in stereotactic ablative body radiotherapy for hepatocellular carcinoma by Atsuto Katano

“…This review summarizes recent advances in AI applications across the SABR workflow, including automated contouring, knowledge-based planning, fluence prediction via deep learning, respiratory motion modeling, liver function estimation, and prognostic modeling. Clinical studies have demonstrated notable benefits, such as a reduction in contouring time and improved dosimetric quality using machine learning–based optimization algorithms. …”
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Energy Saving in Building Air-Conditioning Systems Based on Hippopotamus Optimization Algorithm for Optimizing Cooling Water Temperature by Yiyang Zheng, Yaping Gao, Jianwen Gao

“…Therefore, this study focuses on optimizing the cooling tower outlet water temperature control point in central air-conditioning systems. …”
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Effects of inspiratory muscle training on 1RM performance and body composition in professional natural bodybuilders by Baha Engin Çelikel, Coşkun Yılmaz, Alper Demir, Süreyya Yonca Sezer, Levent Ceylan, Tülay Ceylan, Çetin Tan

“…The mean circumferences of the shoulder (p = 0.004), chest (p = 0.008), arm (p = 0.004), and neck (p = 0.003) improved more in the IMT group than in the CON group. A reduction in abdominal measurement was observed in the IMT group (p = 0.039), whereas no notable discrepancy was identified in body fat percentage (p = 0.295).ConclusionIn conclusion we identified that the addition of progressive loading inspiratory muscle training for competition preparation programs in professional natural bodybuilders will further improve their respiratory function, respiratory muscle strength, maximal strength, and muscle development. …”
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Chlorinated perfluoroalkyl ether sulfonate impairs proliferation and differentiation of neural stem cells via oxidative stress by Yaxin HAN, Longfei FENG, Zhijun ZHOU, Xiuli CHANG

“…The ATP levels after the F-53B exposure decreased to 62.4% relative to the control group (P<0.001). Furthermore, the mRNA expression levels of PINK1 and Par after the F-53B exposure were notably reduced (P<0.05).ConclusionF-53B may induce oxidative stress, thereby disrupting mitochondrial morphology and function while inhibiting the PINK1/Parkin-mediated mitophagy pathway, ultimately leading to impaired neural stem cell proliferation and abnormal differentiation. …”
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Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies. by Ilaria Vaccari, Giorgia Dina, Hélène Tronchère, Emily Kaufman, Gaëtan Chicanne, Federica Cerri, Lawrence Wrabetz, Bernard Payrastre, Angelo Quattrini, Lois S Weisman, Miriam H Meisler, Alessandra Bolino

“…Here we provide strong evidence that Mtmr2 and Fig4 functionally interact in both Schwann cells and neurons, and we reveal for the first time a role of Mtmr2 in neurons in vivo. …”
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The suberin transporter StABCG1 is required for barrier formation in potato leaves by Elvio Henrique Benatto Perino, Ulrike Smolka, Karin Gorzolka, Ramona Grützner, Sylvestre Marillonnet, Khabat Vahabi, Sabine Rosahl

“…Levels of hydroxycinnamic acid amides, acting in defense and in cell wall reinforcement, were drastically enhanced in CRISPR compared to control plants. These results suggest that the reduction in suberin formation around wounded tissue leads to a loss of barrier function, resulting in tissue browning due to enhanced exposure to oxygen.…”
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Mitochondrial Respiration Is Decreased in Rat Kidney Following Fetal Exposure to a Maternal Low-Protein Diet by Sarah Engeham, Kennedy Mdaki, Kirsty Jewell, Ruth Austin, Alexander N. Lehner, Simon C. Langley-Evans

“…Maternal protein restriction in rat pregnancy is associated with impaired renal development and age-related loss of renal function in the resulting offspring. Pregnant rats were fed either control or low-protein (LP) diets, and kidneys from their male offspring were collected at 4, 13, or 16 weeks of age. …”
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PROGRESSING CHRONIC KIDNEY DISEASE AND THE 12-MONTH DYNAMICS OF CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH ARTERIAL HYPERTENSION AND TYPE 2 DIABETES MELLITUS by A. V. Markova, Yu. G. Schwartz

“…In most patients with AH and DM-2, adequate glycemia control, standard antihypertensive treatment, and statin therapy for 12 months were associated with minimal changes in CVD RFs and with a significant deterioration in renal function. …”
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Research on downhole drilling target detection based on improved Yolov8n by Jierui Ling, Zhibo Fu, Xinpeng Yuan

“…The Focaler_MDPIoU loss function was introduced to replace the CIoU loss function, and combined with a lightweight MLCA attention mechanism, a new convolutional block structure was formed, thereby enabling better feature fusion and helping the model focus more centrally on the important parts of the input image. …”
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Losartan in postmenopausal women with essential arterial hypertension by O. N. Tkacheva, A. V. Barabashkina, I. M. Novikova, N. V. Sharashkina

“…In postmenopausal women with AH, adding losartan to the AHT scheme demonstrated good antihypertensive effectiveness, insulin sensitivity normalization, endothelial function and lipid profile improvement. Among women receiving AHT and HRT, antihypertensive effect, as well as beneficial effects on endothelial function and lipid profile, was greater than in women receiving AHT only.…”
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Durability Evaluation of Concrete with Multiadmixtures under Salt Freeze-Thaw Cycles Based on Surface Resistivity by Shibin Luo, Wei Liang, Hua Wang, Wensheng Wang, Rongjun Zou

“…Moreover, surface resistivity of concrete has a good exponential function relationship with strength and a good power function relationship with rapid chloride permeability. …”
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Effects of Cannabinoids Use in Temporomandibular Disorders: A Scoping Review by Letícia da Costa Siqueira, Camila Freire Brant, Jovânia Alves Oliveira, Mayra Resende Azevedo, Carolina Aparecida de Faria Almeida, Suzane Cristina Pigossi, Daniel Augusto de Faria Almeida

“…The observational and interventional studies reported pain reduction, improvement in function, and better health quality with cannabis use. …”
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Role of zinc and vitamin D in modulating diabetic nephropathy in experimental models by Mahmoud Fadl Bakr, Mahmoud A. Elrehany, Othman A. Othman

“…Elevated levels of kidney function markers and other biochemical parameters were decreased by administering zinc and Vit D, but Zn produced the greatest reduction. …”
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Comparative Analysis of Reinforcement Learning Approaches for Multi-Objective Optimization in Residential Hybrid Energy Systems by Yang Xu, Yanxue Li, Weijun Gao

“…This paper presents a DRL control method intended to lower energy expenses and elevate renewable energy usage by optimizing the actions of the battery and heat pump in HEMS. …”
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Mixed-Effects Model to Assess the Effect of Disengagements on Speed of an Automated Shuttle with Sensors for Localization, Navigation, and Obstacle Detection by Abhinav Grandhi, Ninad Gore, Srinivas S. Pulugurtha

“…A multi-level mixed-effects Gaussian regression model with a log-link function was employed to analyze the effect of disengagement events on the automated shuttle speed, while accounting for control variables such as roadway geometry, weather conditions, time-of-the-day, day-of-the-week, and number of intermediate stops. …”
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Impairment of neuronal activity in the dorsolateral prefrontal cortex occurs early in parkinsonism by Noah Hjelle, Biswaranjan Mohanty, Tanner Hubbard, Matthew D. Johnson, Jing Wang, Luke A. Johnson, Jerrold L. Vitek

“…Little is known, however, regarding how neuronal activity in the executive control network of the brain changes in the parkinsonian condition.ObjectiveInvestigate the impact of parkinsonism on neuronal activity in the dorsolateral prefrontal cortex (DLPFC), a key region in executive control, during a go/nogo reaching task.MethodsUsing a within-subject design, single and multi-unit neuronal activity was recorded in the DLPFC of a nonhuman primate (n = 1) before and after the induction of mild parkinsonism using the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).ResultsCoincident with development of mild parkinsonian motor signs, there was a marked reduction in the percentage of DLPFC cells with significant task-related firing rate modulation during go and nogo conditions.ConclusionThese results suggest that DLPFC dysfunction may occur early in parkinsonism and contribute to cognitive impairments and disrupted executive function often observed in PD patients.…”
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Elevation Error Prediction of Continuous Beam Cantilever Construction Phase Based on LS-SVM by Xilong Zheng, Yunfeng Hu, Baitao Sun

“…Under the verification of the elevation control results in the cantilever stage, LS-SVM elevation error prediction is used for controlling the elevation of the bridge and solves the problem–predictive control successfully which is caused for few beam blocks in the cantilever phase of a continuous girder bridge.…”
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