A peer-support lifestyle intervention for preventing type 2 diabetes in India: A cluster-randomized controlled trial of the Kerala Diabetes Prevention Program. by Kavumpurathu R Thankappan, Thirunavukkarasu Sathish, Robyn J Tapp, Jonathan E Shaw, Mojtaba Lotfaliany, Rory Wolfe, Pilvikki Absetz, Elezebeth Mathews, Zahra Aziz, Emily D Williams, Edwin B Fisher, Paul Z Zimmet, Ajay Mahal, Sajitha Balachandran, Fabrizio D'Esposito, Priyanka Sajeev, Emma Thomas, Brian Oldenburg

“…At 24 months, compared with the control group, intervention participants had a greater reduction in IDRS score (mean difference: -1.50 points, p = 0.022) and alcohol use (RR 0.77, p = 0.018) and a greater increase in fruit and vegetable intake (≥5 servings/day) (RR 1.83, p = 0.008) and physical functioning score of the HRQoL scale (mean difference: 3.9 score, p = 0.016). …”
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Double-blind, randomized, placebo-controlled pilot clinical trial with gamma-band transcranial alternating current stimulation for the treatment of schizophrenia refractory auditor... by Xiaojuan Wang, Xiaochen Zhang, Yuan Chang, Jingmeng Liao, Shuang Liu, Dong Ming

“…Further, functional brain network controllability outcomes showed that the 40Hz-tACS group had increased average controllability (F (1,30) = 6.26, p = 0.018) and decreased modality controllability (F (1,30) = 6.50, p = 0.016) in the right frontal lobe compared to the sham group. …”
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Supplementation with porcine placenta extract reduces negative emotions and enhances positive emotions in healthy adults: a randomized, double-blind, placebo-controlled study by Naoya Morita, Eiichi Hirano

“…The primary endpoint was TMD score, while secondary endpoints included fatigue, quality of life, sleep quality, autonomic function, and stress hormone levels.ResultsThe pPE group showed significant reductions in TMD scores and improvements in Anger-Hostility, Confusion-Bewilderment, Vigor-Activity, and Friendliness subscales compared to the placebo group. …”
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Application of quasi-oppositional driving training-based optimization for a feasible optimal power flow solution of renewable power systems with a unified power flow controller by Tushnik Sarkar, Chandan Paul, Susanta Dutta, Provas Kumar Roy, Ghanshyam G. Tejani, Ghanshyam G. Tejani, Seyed Jalaleddin Mousavirad

“…Obtaining minimum total cost comes under the single-objective function. Simultaneous reduction in the overall cost and emission, concurrent reduction in overall cost and voltage deviation (VD), and simultaneous reduction in overall cost and voltage stability index come under multi-objective cases. …”
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The effects of an immersive virtual reality and telemedicine-based multi-component intervention in individuals with subjective cognitive decline: study protocol of a randomized con... by Maria Stefania De Simone, Maria Stefania De Simone, Silvia Zabberoni, Silvia Zabberoni, Alberto Costa, Alberto Costa, Erika Tenaglia, Erika Tenaglia, Gaetano Tieri

“…The primary outcome is the effect of the multi-component intervention in enhancing objective cognitive functioning. Secondary outcomes include changes in subjective cognitive functioning, psychiatric symptoms, quality of life and functional neural connectivity. …”
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Is there a link between heart rate variability and cognitive decline? A cross-sectional study on patients with mild cognitive impairment and cognitively healthy controls by Bernhard Grässler, Milos Dordevic, Sabine Darius, Fabian Herold, Giuseppe Forte, Corinna Langhans, Nicole Halfpaap, Patrick Müller, Wenzel Glanz, Estélio Henrique Martin Dantas, Irina Böckelmann, Notger Müller, Anita Hökelmann

“…Methods Cardiac autonomic control was assessed by means of heart rate variability (HRV) at resting state and during cognitive tasks in 22 older adults with MCI and 29 healthy controls (HCs). …”
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Perioperative Protocol of Ankle Fracture and Distal Radius Fracture Based on Enhanced Recovery after Surgery Program: A Multicenter Prospective Clinical Controlled study by Ting Li, Zhi-Jian Sun, Yan Zhou, Wei-Tong Sun, Peng-Cheng Wang, Xin-Yu Cai, Jun-Bo Liang, Jing-Ming Dong, Da-Peng Zhou, Kai Yu, Ming-Xin Wu, Jiu-Sheng He, Liang-Yuan Wen, Bao-Qing Yu, Jian Wang, Jun Yang, Feng-Fei Lin, Bing-Zuan Li, Zong-Xin Shi, Bao-Jun Wang, Ai-Guo Wang, Gui-Ling Peng, Xu Sun, Hong-Hao Xiao, Meng Mi, Xia Zhao, Chang-Run Li, Gang Liu, Shao-Liang Li, Hang-Yu Gu, Yuan Zhou, Zhe-Lun Tan, Xin-Bao Wu

“…This is a multicenter prospective clinical controlled study consisting of 323 consecutive adults with ankle fracture from 12 centers and 323 consecutive adults with distal radial fracture from 13 centers scheduled for open reduction and internal fixation between January 2017 and December 2018. …”
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Efficacy of Shenkang Injection combined with renin-angiotensin-aldosterone system blockers in diabetic nephropathy: a systematic review and meta-analysis of randomized controlled t... by Xinyue Zhang, Xuyuan Lao, Shengchun Liao, Chaoyang Ye, Chen Wang

“…Subgroup analysis showed that patients aged ≤55 years had greater reductions in SCr (WMD −25.62, 95% CI −29.41 to −21.83) and BUN (WMD −2.51, 95% CI −2.75 to −2.27). …”
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Blended digital health intervention for adolescents at high risk with digital media use disorders: protocol for a randomised controlled trial within the Res@t-Consortium by Oliver Labrenz, Oliver Labrenz, Lucie Waedel, Lucie Waedel, Michael Kölch, Michael Kölch, Susanne Lezius, Christina Wacker, Antonia Fröhlich, Antonia Fröhlich, Kerstin Paschke, Rainer Thomasius, Olaf Reis, Olaf Reis

“…The efficacy of the app will be evaluated in a randomised controlled trial with a waitlist control group. The primary outcome is the reduction of DMUD symptoms over a 20-week period following the onset of app training. …”
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The Efficacy and Safety of Ferric Carboxymaltose in Heart Failure with Reduced Ejection Fraction and Iron Deficiency: An Updated Systematic Review and Meta-Analysis of Randomized C... by Inderbir Padda, Sneha Annie Sebastian, Daniel Fabian, Yashendra Sethi, Gurpreet Johal

“…Intravenous ferric carboxymaltose (FCM) has been associated with improvements in clinical outcomes, functional capacity, and quality of life (QoL) in patients with HF and ID. …”
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Changes in the Brain-Derived Neurotrophic Factor Are Associated with Improvements in Diabetes Risk Factors after Exercise Training in Adolescents with Obesity: The HEARTY Randomize... by Jeremy J. Walsh, Amedeo D’Angiulli, Jameason D. Cameron, Ronald J. Sigal, Glen P. Kenny, Martin Holcik, Steve Doucette, Angela S. Alberga, Denis Prud’homme, Stasia Hadjiyannakis, Katie Gunnell, Gary S. Goldfield

“…In the exercise group, increases in BDNF were associated with reductions in fasting glucose (β = −6.57, SE = 3.37, p=0.05) and increases in HOMA-B (β = 0.093, SE = 0.03, p=0.004) after controlling for confounders. …”
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Effectiveness of Group Problem Management Plus, a brief psychological intervention for adults affected by humanitarian disasters in Nepal: A cluster randomized controlled trial. by Mark J D Jordans, Brandon A Kohrt, Manaswi Sangraula, Elizabeth L Turner, Xueqi Wang, Pragya Shrestha, Renasha Ghimire, Edith Van't Hof, Richard A Bryant, Katie S Dawson, Kedar Marahatta, Nagendra P Luitel, Mark van Ommeren

“…Among the secondary outcomes, Group PM+ was associated with endline with a larger proportion attaining more than 50% reduction in depression symptoms (29.9% of Group PM+ arm versus 17.3% of control arm, risk ratio = 1.7, 95% CI: 1.2, 2.4, p = 0.002). …”
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Testosterone Deficiency and Lipid Dysregulation in Individuals with Coexisting Hypothyroidism and Type 2 Diabetes: Clinical and Metabolic Implications by Mandayal Jamatia, Mohammad N Khan, Ashok Kumar

“…Aim and background: This study aims to evaluate the biochemical and endocrine changes in individuals with diabetes, hypothyroidism, and their coexistence, focusing on glycemic control, lipid metabolism, and hormonal balance. Understanding their interplay is crucial for optimizing disease management, enabling early intervention, and improving patient outcomes through personalized therapeutic strategies and risk reduction approaches. …”
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Exploring the Cardiovascular Potential of Artichoke—A Comprehensive Review by Henrique Silva, Avina Mahendra Daia

“…Standardized formulations and well-controlled clinical studies will be required to clarify its therapeutic role.…”
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Food science and COVID-19 by Klaus W. Lange

“…High-energy diets and obesity are major risk factors for a more severe course of COVID-19.Therefore, population-wide body weight control and weight reduction in overweight people are important preventive measures. …”
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Global Trends in the Relationship Between Chronic Air Pollution Exposure, Physical Activity and Lung Function in Youth Aged 5–18 Years With and Without Asthma: A Systematic Review... by Samanta Gudziunaite, Kelly A. Mackintosh, Gwyneth A. Davies, Kathryn A. Jordan, Paul D. Lewis, Chris J. Griffiths, T. Alexander Swain, Melitta A. McNarry

“…Objectives The aim was to explore the relationship between air pollution and lung function and the influence of asthma status and physical activity in children and adolescents. …”
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The benefits of early palliative care on psychological well-being, functional status, and health-related quality of life among cancer patients and their caregivers: a systematic re... by Hartiah Haroen, Sidik Maulana, Hasniatisari Harun, Ristina Mirwanti, Citra Windani Mambang Sari, Hesti Platini, Novita Intan Arovah, Padila Padila, Shakira Amirah, Jerico Franciscus Pardosi

“…This study included randomized controlled trial (RCT) and pilot-RCT studies reporting psychological outcomes (anxiety, depression), functional status, QoL, and satisfaction in cancer patients and their caregivers. …”
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Efficacy of paliperidone palmitate once-monthly (PP1M) in improving social functioning and reducing caregiver burden in patients with schizophrenia: a six-month follow-up study by Ling Dong, Xiao-Yan Liu, Wen-Cai Chen, Xiao-Xin Dong, Fan Wang, Si-Jing Chen, Xiu-Jun Liu

“…Conclusion PP1M treatment effectively controlled symptoms, improved social functioning, and reduced caregiver burden in schizophrenia patients. …”
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Metabolomics and microscopic profiling of flaxseed meal- incorporated Peda by Sachin Maurya, Tarun Verma, Ankur Aggarwal, Manish Kumar Singh, Abhishek Dutt Tripathi, Ankur Trivedi

“…The optimized Peda (2%) exhibited significantly reduction in moisture (39.6%) and water activity (18.9%), while significantly increasing crude fiber (1.88%), protein (26.4%), fat (8%) and DPPH inhibition (274.5%) as compared to control Peda. …”
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Auricular Acupressure Versus an Intermittent Low-Carbohydrate Diet in Children With Overweight or Obesity With Gastric-Heat and Dampness-Obstruction Syndrome: Protocol for a Random... by Wen Sun, Jingwei He, Wenqin Wang, Chen Lu, Yating Lin, Yalan Dou, Weili Yan, Jian Yu

“…However, there is limited high-quality evidence about effectiveness and safety in weight control and reducing cardiometabolic risk in the pediatric population. …”
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