Therapeutic effect of two muscle strengthening programs in patients with patellofemoral pain syndrome. A randomized controlled clinical trial by Luisa Fernanda Prieto-García, Edgar Cortés-Reyes, Gilberto Lara-Cotacio, Lizeth Catherine Rodríguez-Corredor

“…Conservative treatment reduces pain and improves functional capacity in the short and medium-term. …”
Get full text

Non-Pharmacological Interventions for Chronic Pain Management: A Narrative Review by Mohammed Albesher, Mohammed AlKhalifah, Abdulaziz Hazazi, Ghassan Hakeem, Bader Almogbel

“…Results: Physical therapies, such as manual therapy, exercise therapy, and therapeutic modalities, demonstrate benefits in improving physical function and reducing chronic pain. Psychological therapies, including cognitive behavioural therapy (CBT), mindfulness-based stress reduction (MBSR), and acceptance and commitment therapy (ACT), are crucial for addressing the psychological and emotional dimensions of chronic pain. …”
Get full text

Efficacy and safety of vitamin E as adjunctive therapy for epilepsy: a systematic review and meta-analysis of randomized control trials by Yanfei Li, Yanfei Li, Gefei He, Gefei He, Juanjuan Huang, Juanjuan Huang, Lin Hu, Lin Hu

“…Vitamin E had a potential advantage in reducing seizure frequency by >75% (RR = 1.73, 95% confidence interval (CI) (1.31, 2.28), p < 0.01), compared with the control group. Subgroup analysis showed a statistically significant difference in the reduction of seizure frequency by >50% (RR = 1.58, 95% CI (1.27, 1.96), p < 0.01) between the vitamin E group and the control group, especially in children (RR = 1.69, 95% CI (1.29, 2.20), p < 0.01). …”
Get full text

Enhanced nonlinear sliding mode control technique for wind power generation systems application: Theoretical design and comparative study by Yattou El Fadili, Ismail Boumhidi

“…Additionally, this controller ensures system stability, with a Lyapunov function standard deviation of 0.0105 and 0.1755 for the first and second tests, respectively. …”
Get full text

Unveiling the Cardioprotective Potential of Hydroxytyrosol: Insights from an Acute Myocardial Infarction Model by Alejandra Bermúdez-Oria, Eugenia Godoy, Virginia Pérez, Camila Musci Ferrari, Martin Donato, Juan Fernández-Bolaños, Tamara Zaobornyj, Verónica D’Annunzio

“…Mice were administered a single intraperitoneal dose of HT (10 mg/kg) 24 h prior to the I/R protocols, and parameters such as the infarct size, mitochondrial function, and redox balance were assessed. The results revealed a remarkable 57% reduction in infarct size in HT-treated mice compared to untreated controls. …”
Get full text

Assessing rehabilitation potential of the masticatory musculature in patients with temporomandibular myofascial pain syndrome: A randomized prospective controlled study by E. N. Iarygina, V. V. Shkarin, Yu. A. Makedonova, S. V. Dyachenko

“…Notably, Group II (patients received a device-based complex of facial and mandibular gymnastics) revealed a statistically significant difference in both pre-treatment measurements and the control group indications. A persistent reduction in the mean amplitude of the temporal and masseter muscles, as well as their symmetry index, torsional index, and masseteric index, was observed. …”
Get full text

A comprehensive examination and analysis of the effectiveness and safety of finerenone for the treatment of diabetic kidney disease: a systematic review and meta-analysis by Jianyu Chen, Jianyu Chen, Jisu Xue, Jiahui Chen, Jiahui Chen, Tingfei Xie, Tingfei Xie, Xiaolu Sui, Xiaolu Sui, Yanzi Zhang, Yanzi Zhang, Aisha Zhang, Aisha Zhang, Yunpeng Xu, Yunpeng Xu, Jihong Chen, Jihong Chen

Get full text

Exercise interventions of ≥8 weeks improve body composition, physical function, metabolism, and inflammation in older adults with stage I sarcopenic obesity: a systematic review an... by Huiting Wei, Huiting Wei, Jiabao Zhang, Jiabao Zhang, Kaiyin Cui, Kaiyin Cui, Hao Su, Hao Su

“…Physical function improves with both RT and CE, and RT is better for muscle strength, while CE benefits metabolism and inflammation. …”
Get full text

Functional benefits of a chorioretinal anastomosis at 2 years in eyes with a central retinal vein occlusion treated with ranibizumab compared with ranibizumab monotherapy by David A Mackey, Paul G Sanfilippo, Fred K Chen, Ian L McAllister, Lynne A Smithies

“…The mean BCVA was averaged across all timepoints between the control and functioning L-CRA groups (average difference=11.46 (3.16 to 19.75) letters, p=0.01). …”
Get full text

Functional interactions between the erupted/tsg101 growth suppressor gene and the DaPKC and rbf1 genes in Drosophila imaginal disc tumors. by M Melissa Gilbert, Brian S Robinson, Kenneth H Moberg

“…Excess cell division is postulated to be a primary cause of these 'neoplastic' phenotypes, but the autonomous effect of these mutations on cell cycle control has not been examined.<h4>Principal findings</h4>Here we show that disc cells lacking ept function display an altered cell cycle profile indicative of deregulated progression through the G1-to-S phase transition and express reduced levels of the tumor suppressor ortholog and G1/S inhibitor Rbf1. …”
Get full text

Cerebral blood flow and arterial transit time responses to exercise training in older adults by Jack Feron, Foyzul Rahman, Sindre H Fosstveit, Kelsey E Joyce, Ahmed Gilani, Hilde Lohne-Seiler, Sveinung Berntsen, Karen J Mullinger, Katrien Segaert, Samuel J E Lucas

“…Exercise training can improve aspects of brain health in older adults, yet its effects on CBFGM and ATTGM remain unclear. This randomised controlled trial assessed responses of CBFGM and ATTGM to a 26 week exercise intervention in 65 healthy older adults (control: n = 33, exercise: n = 32, aged 60–81 years), including whether changes in CBFGM or ATTGM were associated with changes in cognitive functions. …”
Get full text

Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial by Jean-Yves Reginster, J Badurski, N Bellamy, W Bensen, R Chapurlat, X Chevalier, C Christiansen, H Genant, F Navarro, E Nasonov, P N Sambrook, T D Spector, C Cooper

“…There were greater reductions in total WOMAC score (p=0.045), pain subscore (p=0.028), physical function subscore (p=0.099) and knee pain (p=0.065) with strontium ranelate 2 g/day. …”
Get full text

Application Efficacy of Nursing Interventions Guided by the Medication-Psychological-Nursing-Family-Support (MPNFS) Framework in Mitigating Cancer-Related Fatigue and Enhancing Pul... by Zhu Y, Liu Y

“…Outcomes were compared using validated scales for CRF (Cancer Fatigue Scale, CFS), negative emotions (Self-Rating Anxiety Scale, SAS; Self-Rating Depression Scale, SDS), quality of life (EORTC QLQ-C30), nutritional status (serum albumin, ALB; total protein, TP), pulmonary function (forced vital capacity, FVC; vital capacity, VC), and complication incidence.Results: CRF: After 6 weeks, cognitive, emotional, and physical fatigue scores decreased in both groups, with greater reductions in the MPNFS group (P&lt; 0.05). …”
Get full text

Effectiveness and safety of adjuvant software based on virtual reality for post-thoracoscopic surgery pain: study protocol for a randomized controlled trial by Xijia Feng, Wei Guo, Benyuan Jiang, Tong Li, Yi Lu, Song Xu, Wenzhao Zhong, Hecheng Li

“…Abstract Background Postoperative pain can significantly impair functional recovery and diminish the quality of life in patients who have undergone thoracoscopic surgery. …”
Get full text

Optimistic effects of dual nano-encapsulated probiotics on breeders laying performance, intestinal barrier functions, immunity and resistance against Salmonella Typhimurium challen... by Mohamed Tharwat Elabbasy, Asmaa T. Y. Kishawy, Walaa S. Abdelaziz, Ahmed Abdelfattah Hassan, Hend S. Nada, Reham A. Elbhnsawy, Amany M. Shosha, Dina Ibrahim, Fatma Eldemery, Shimaa A. E. Atwa, Wafaa R. I. A. Sherief, Eman S. El-Shetry, Ayman A. Saleh, Doaa Ibrahim

Get full text

Event-related theta synchronization over sensorimotor areas differs between younger and older adults and is related to bimanual motor control by Andreas Wulff-Abramsson, Ana Zvornik, Keenie Ayla Andersen, Yan Yang, Mikael Novén, Jesper Lundbye-Jensen, Leo Tomasevic, Anke Ninija Karabanov

Get full text

The effect of probiotics on gestational diabetes mellitus: an umbrella meta-analysis by Guixia Sun, Hongli Hou, Shanshan Yang

“…Conclusions Supplementation with probiotics could improve glycemic control in women with GDM. The effects of probiotics on HOMA-IR, HOMA-B, and fasting insulin were clinically important, while, their effect on FBS was not clinically important.…”
Get full text

Dietary resistant starch protects against post-antibiotic intestinal damage by restoring microbial homeostasis and preserving intestinal barrier function in meat duck by Simeng Qin, Yifeng Zhu, Gang Tian, Martin Blomberg Jensen, Keying Zhang, Xuemei Ding, Shiping Bai, Jianping Wang, Yue Xuan, Qiufeng Zeng

“…Whereafter, in addition to the control group, ducks treated with antibiotics for 7 consecutive days were further allocated to two groups and fed the basal diet and RS diet that derived from 12 % raw potato starch until 21 d. …”
Get full text

Coptisine ameliorates colitis in mice by modulating cPLA2/TRPM8/CGRP-1 signaling pathways and strengthening intestinal barrier function by Wenbin Wu, Changcheng Shu, Lisheng Chen, Shizhang Wei, Manyi Jing, Hui Li, Haotian Li, Yanling Zhao

“…Histopathological analysis indicated a reduction in intestinal inflammation and an enhancement of intestinal mucosal barrier function. …”
Get full text

Efficacy of Vonoprazan 10 mg and 20 mg for Patients With Proton Pump Inhibitor‐Refractory Functional Dyspepsia: A Double‐Blinded, Randomized Study by Chalermrat Bunchorntavakul, Pantaree Jaigla

“…ABSTRACT Background A proportion of patients with functional dyspepsia (FD) have inadequate symptom control with proton pump inhibitors (PPIs) treatment. …”
Get full text