GB18-06, a nanobody targeting GDF15, effectively alleviates weight loss and restores physical function in cachexia models by Yu Huang, Jinyong Wang, Xiling Wei, Hui Zhang, Wei Shang, Xiangling Zhang, Lanjiao Zhai, Xi Chen, Huiming Li, Suofu Qin

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The effect of manual techniques on maximum muscle activity electromyography, functional disability, and pain in women with non-specific chronic low back pain by hadi miri, mina haghighi, arezoo mohammadi

“…These improvements in muscle condition and functional disability may lead to a reduction in pain experienced by individuals with NSCLBP.…”
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Nonclassical Parametric Variational Technique to Manipulability Control of a Serial-Link Robot That Is Used in Treatment of Femoral Shaft Fractures by Ghazwa F. Abd

“…The dynamics of the reduction robot are analysed using the implicit function theorem, which allows us to address the reduced problem. …”
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Acupuncture plus night splint for quality of life and disability in patients with carpal tunnel syndrome: a randomized controlled trial by Nihal Tezel, Ebru Umay, Volkan Yılmaz, Aytul Cakci

“…Acupuncture and night splinting was applied two times a week for five weeks, while the control group received night splinting only. Outcomes measured were Quality of life (Nottingham Health Profile, NHP), function (Boston Carpal Tunnel Questionnaire) and pain (visual analogue scale, VAS). …”
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Energy-Efficient Battery Thermal Management in Electric Vehicles Using Artificial-Neural-Network-Based Model Predictive Control by Kiheon Nam, Changsun Ahn

“…To mitigate oscillatory control inputs observed in conventional MPC, an infinity-horizon MPC framework was introduced, incorporating a value function that accounts for system behavior beyond the prediction horizon. …”
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Combining high-pressure processing and low storage temperature to extend the functionality shelf life of low-moisture, part-skim mozzarella cheese by L.A. Jiménez-Maroto, S. Govindasamy-Lucey, J.J. Jaeggi, M.E. Johnson, J.A. Lucey

“…Cheeses were stored for 2 wk at 4°C, divided into control (non-HPP) and HPP (600 MPa for 3 min) groups, and stored at 3 different temperatures (4, 0, and −18°C) for 365 d. …”
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Exosomal CD73 from serum of patients with melanoma suppresses lymphocyte functions and is associated with therapy resistance to anti-PD-1 agents by Mariaelena Capone, Gabriele Madonna, Ester Simeone, Paolo A Ascierto, Antonio Sorrentino, Roberta Turiello, Elva Morretta, Maria Chiara Monti, Rosa Azzaro, Silvana Morello, Pasquale Del Gaudio

“…Immunosuppressive pathways associated with exosomes can affect T-cell function and the therapeutic efficacy of anti-programmed cell-death protein 1 (anti-PD-1) therapy. …”
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Sustainable one-part engineered geopolymer composite with thermal insulation in coastal region: Utilizing red mud dual-function as precursor and activator by Hangbo Bi, Ziming Tang, Fei Wang, Lingzhi Li, Bakhadir Mirzaev, Kequan Yu, Lingfei Liu

“…Remarkably, EGCs containing 50 % and 80 % RM precursors exhibited compressive strengths exceeding 20 MPa and 10 MPa, respectively, which remained above 10 MPa even at 25 % alkali reduction. In addition, at merely 0.5 % fiber dosage, the EGC demonstrated tensile strength above 2 MPa, strain capacity exceeding 4 %, and controlled crack widths of around 200 μm. …”
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Reversed Effects of Intermittent Theta Burst Stimulation following Motor Training That Vary as a Function of Training-Induced Changes in Corticospinal Excitability by Tino Stöckel, Jeffery J. Summers, Mark R. Hinder

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Functionally graded scaffold with M2 macrophage-derived LncRNA-Encoded peptide: Mechanistic and therapeutic evaluation for rotator cuff repair by Hao Feng, Gonghao Zhang, Li Xiong, Panpan Shang, Xiao Yu, Bin Chai, Lu Han, Shuqi Lou, Muhammad Shafiq, Yiying Zhang, Mohamed EL-Newehy, Meera Moydeen Abdulhameed, Zhengchao Yuan, Xiumei Mo, Yunhan Ji

“…Through a multidimensional collaborative repair strategy, this functionally graded scaffold not only mimicked the tendon–bone interface, but also significantly suppressed local inflammation at the interface, as evidenced by a 60.6 % and 66.5 % reduction in IL-6–positive areas at 2 and 4 months, respectively, compared with the control group. …”
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A MPCC-Based Variable Sampling Time Interleaving Method for a Two-Phase Totem-Pole Bridgeless Boost PFC Converter by Hyun-Gyu Koh, Hyeon-Joon Ko, Yeong-Jun Choi

“…This paper proposes a Model Predictive Current Control (MPCC) based variable sampling time interleaving method to improve the current shaping ability, power conversion efficiency, power density and current ripple reduction of a two-phase totem pole bridgeless boost power factor correction (PFC) converter. …”
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A Stable Distributed Neural Controller for Physically Coupled Networked Discrete-Time System via Online Reinforcement Learning by Jian Sun, Jie Li

“…Each controller includes a critic network and action network for approximating strategy utility function and desired control law, respectively. …”
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CCL2 Inhibitor Bindarit Improve Postoperative Cognitive Function by Attenuating Pericyte Loss-Related Blood–Brain Barrier Disruption and Neuroinflammation by Hui Yuan, Bo Lu, Daofan Sun, Junping Chen, Xiangming Fang

“…Bindarit effectively inhibited the surgery-induced increase in hippocampal CCL2 expression and improved postoperative cognitive function. Behavioral tests, including the open field (OF) test and novel object recognition (NOR) test, indicated enhanced locomotor activity and short-term memory in Bindarit-treated mice compared to controls. …”
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Competitive Roles of DNRA and Denitrification on Organic Nitrogen Dynamics in Partially Saturated Soil‐Water Systems by Lecheng Liu, Tianyuan Zheng, Yingying Qiu, Yujie Hao, Haoran Ma, Xilai Zheng, Alberto Guadagnini

“…Our analysis further suggests the relevance of hydrogeochemical factors (e.g., moisture variation, soil texture, and C/N ratio) on DON transformation through the influence of functional microorganisms. These insights advance our understanding of nitrogen dynamics in agroecosystems, which has significant implications for environmental management practices aimed at controlling NO3−‐N pollution in partially saturated soils.…”
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Limited and inconclusive effects of computer-based neurocognitive training on PTSD, comorbid depression and executive functioning: a systematic review and meta-analysis by Patric Muschner, Lena Goldschmidt, Luisa Sophie Gröning, Gerd-Dieter Willmund, Martina Piefke

“…These findings suggest that c-bnt may contribute to reductions in PTSD symptoms and potentially benefit comorbid depression and neurocognitive functions, particularly working memory and cognitive flexibility. …”
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Still a dilemma! Are vonoprazan and esomeprazole attenuating the antiplatelet function of clopidogrel when taken concomitantly? A systematic review and meta-analysis by Eman Youssef, Aliaa Gamal, Hagar Youssef

“…Conclusion Both vonoprazan and esomeprazole reduce the antiplatelet function of clopidogrel to a certain extent. However, vonoprazan may have a more pronounced impact on attenuating clopidogrel’s antiplatelet function than esomeprazole. …”
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Fibrocytes in early and long-standing rheumatoid arthritis: a 6-month trial with repeated synovial biopsy, imaging and lung function test by Søren Andreas Just, Frances Humby, Hanne Lindegaard, Pia Veldt Larsen, Christian Nielsen, Jens Christian Werlinrud, Henrik Daa Schrøder, Trine Torfing, Eva Kildall Hejbøl, Helene Broch Tenstad, Torben Barington

“…Sixteen patients undergoing wrist arthroscopy were healthy controls. Patients with RA underwent pulmonary function tests, ultrasound and synovial ultrasound-guided needle biopsy of the same wrist at baseline and 6 months. …”
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Associations of Functional MicroRNA Binding Site Polymorphisms in IL23/Th17 Inflammatory Pathway Genes with Gastric Cancer Risk by Kaiyan Dong, Yajuan Xu, Qian Yang, Jiachen Shi, Jicheng Jiang, Yi Chen, Chunhua Song, Kaijuan Wang

“…In this study, four miRNA binding site SNPs (rs3748067 of IL17A, rs887796, rs1468488 of IL17RA, and rs10889677 of IL23R) were genotyped from 500 patients and 500 controls. Unconditional logistic regression analyses and multifactor dimensionality reduction software were used to evaluate the relationships of SNPs with GC and gene-environment interactions, respectively. …”
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Optical band gap modulation in functionalized chitosan biopolymer hybrids using absorption and derivative spectrum fitting methods: A spectroscopic analysis by Dyari M. Mamand, Dana S. Muhammad, Daron Q. Muheddin, Karzan A. Abdalkarim, Dana A. Tahir, Hawkar A. Muhammad, Shujahadeen B. Aziz, Sarkawt A. Hussen, Jamal Hassan

“…The results indicate that CS with Mn2+-complexes can produce polymer hybrids with high absorption, high refractive index and controlled optical band gaps, with a significant reduction from 6.24 eV to 1.21 eV. …”
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<i>Artemisia argyi</i>-Mediated Synthesis of Monodisperse Silver Nanoparticles as Components of Bioactive Nanofibrous Dressings with Dual Antibacterial and Regenerative Functions by Jiale Wang, Jiawei Guan, Xingyu Ma, Dongyang Zhao, Yongqiang Han, Dongdong Guo, Jialin Bai, Zisheng Guo, Xiaojun Zhang

“…When integrated into polylactic acid/collagen type I (PLA/Col1) nanofibrous matrices, the optimized 0.03% AgNPs/PLA/Col1 dressing significantly accelerated wound healing in a diabetic rat model, achieving 94.62 ± 2.64% wound closure by day 14 compared to 65.81 ± 1.80% observed in untreated controls. Histological analyses revealed a dual-functional mechanism wherein controlled silver ion release provided sustained antibacterial protection, while concurrently promoting tissue regeneration characterized by enhanced collagen deposition, reduced inflammation, and increased neovascularization. …”
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