Ultra-small phospholipid nanoparticles in the treatment of combined hyperlipidemia: a randomized placebo-controlled clinical trial by Alexander Archakov, Valery Kukharchuk, Andrey Lisitsa, Elena Ponomarenko, Yulia Romashova, Tatiana Pleshakova, Elena Yarovaya, Vladimir Kutsenko, Maria Guseva, Valery Beregovykh, Olga Ipatova, Marina Zubareva, Elena Tikhonova, Sergei Ivanov, Farid Bedretdinov, Sergey Markin

“…Experimental approach: A randomized, double-blinded, placebo-controlled phase II trial was conducted on 100 patients. …”
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Design of reinforcement learning based robust μ-synthesis controller for single phase grid-connected VSI by P. Shambhu Prasad, Alivelu M. Parimi

“…The order of the controller has been reduced with a balanced model reduction approach. …”
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Structural and parametric synthesis of anti-average control algorithms for realizing adaptive frequency operating automaticselectrotechnical systems by V. R. Ivanovа, I. Y. Ivanov, V. V. Novokreshchenov

“…To achieve this goal, we use the method of structural and parametric synthesis of emergency control algorithms, which consists in creating a composite algorithmic model of adaptive FDA. …”
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Empowering small-scale industries food safety: Designing fuzzy controlled pulse electric field pasteurization by Ika Noer Syamsiana, Mohammad Wildan Fikri Amrullah, Muhammad Akhlis Rizza, Wahyu Aulia Nurwicaksana, Zakiyah Irfin, Ratna Ika Putri, Cahya Rahmad

“…The objective is to develop a more efficient and economical alternative solution for milk preservation. PEF technology functions by applying a high-voltage pulse generator is developed using a flyback transformer, with duty cycle and frequency settings determined through the application of fuzzy logic control (FLC). …”
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Effects of ginger supplementation in individuals with mild to moderate joint pain I: ratings of pain, functional capacity, and markers of inflammation by Jacob Broeckel, Landry Estes, Megan Leonard, Broderick Dickerson, Drew E. Gonzalez, Martin Purpura, Ralf Jäger, Ryan Sowinski, Christopher J. Rasmussen, Richard B. Kreider

“…The purpose of this study was to determine whether a specialized ginger extract effects pain perception, functional capacity and markers of inflammation.Methods 30 men and women (56.0 ± 9.0 years, 164.4 ± 14 cm, 86.5 ± 20.9 kg, 31.0 ± 7.5 kg/m2) with a history of mild to severe joint and muscle pain and inflammation participated in a randomized, placebo-controlled, parallel-arm, intervention trial. …”
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Laser Acupuncture for the Pain of Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Zeng DH, Yuan DN, Zhou QQ, Liu YY, Ma WB, Lan L

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Plant growth-promoting bacteria as biological control agents for sustainable agriculture: targeting root-knot nematodes by Adriana S. Mata, Carlos Cruz, João Rodrigues Gaspar, Isabel Abrantes, Isabel Luci Conceição, Paula V. Morais, Diogo Neves Proença, Diogo Neves Proença

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Research on Seismic Signal Denoising Model Based on DnCNN Network by Li Duan, Jianxian Cai, Li Wang, Yan Shi

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Controlling CRISPR-Cas9 genome editing in human cells using a molecular glue degrader by Namita Khajanchi, Vrusha Patel, Ronak Dua, Meha Kabra, Bikash R. Pattnaik, Krishanu Saha

“…Cells edited with the Cas9-d system were healthy and functional, exhibiting minimal toxicity from using the strategy. …”
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Post-covid-19 conditions in adults: systematic review and meta-analysis of health outcomes in controlled studies by Christa Scheidt-Nave, Maria-Inti Metzendorf, Luis Ignacio Garegnani, Juan Victor Ariel Franco, Katharina Heldt, Rebekka Mumm

“…Based on five studies, we found a reduction in overall quality of life between individuals with confirmed SARS-CoV-2 infection versus controls at six to 24 months follow-up, although heterogeneity was very high (mean difference in EQ-5D scale −5.28 (95% confidence interval −7.88 to 2.68; I2=93.81%). …”
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The clinical efficacy of intravascular laser irradiation of blood (ILIB): A narrative review of randomized controlled trial by Leonardo Díaz, Alain Chaple Gil, Alfredo Von Marttens, Javier Basualdo, Claudio Sotomayor, Alexis Vera Becerra, Víctor Beltrán, Gilbert Jorquera, Rodrigo Caviedes, Eduardo Fernández

“…Background: Intravascular Laser Irradiation of Blood (ILIB) is a systemic application of photobiomodulation therapy (PBMT), proposed to modulate oxidative stress, inflammation, and mitochondrial function. Although its clinical use is expanding across various medical conditions, a consolidated evaluation of its therapeutic relevance remains lacking. …”
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The benefit of inhibitory control training for insomnia with short sleep duration phenotype: a pilot randomized trial by Haobo Zhang, Zhangwei Lv, Hanfei Chen, Zijie Tang, Xu Lei

“…Following adaptive training, the ISSD training sub-group showed decreased scores in PSQI (p = 0.039) and ISI (p = 0.053) compared to their blank control sub-group. In the INSD groups, both training and blank control sub-groups demonstrated reductions in PSQI (p < 0.001), ISI (p < 0.001), and the cognitive arousal sub-dimension of the PSAS scores (p = 0.003) in the post-session test. …”
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KArAT (Knee Arthroplasty Activity Trial): Rationale and design features of a multicenter randomized controlled trial by Elena Losina, Jamie E. Collins, Mahima Kumara, Linda Ehrlich-Jones, Maame Opare-Addo, Clare Safran-Norton, Neil A. Segal, Lauren M. Mitchell, Paul T. Kopp, Faith Selzer, Hanna Mass, Michael Paskewicz, Rowland W. Chang, Dorothy Dunlop, Antonia F. Chen, Samuel Lerner, Samantha Chin, Christine Pellegrini, Jeffrey N. Katz

“…Despite substantial pain reduction and functional improvements, physical activity (PA) does not necessarily increase post TKA. …”
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A randomised, double-blind clinical study into the effect of zinc citrate trihydrate toothpaste on oral plaque microbiome ecology and function by Suzi Elizabeth Adams, Andrew Kenneth Cawley, David Arnold, Michael John Hoptroff, Vera Slomka, Jane Reid Matheson, Robert Edward Marriott, Matthew Ronald Gemmell, Philip David Marsh

“…Analysis of microbiome function based on predicted metagenomic and metatranscriptomic analysis show that use of the zinc toothpaste is associated with an in-vivo reduction in glycolysis, consistent with the mode of action of zinc and, increases in processes linked to gum-health (lysine biosynthesis), and to whole-body health (nitrate reduction). …”
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Concurrent vs. sequential chemoradiotherapy: a survival boost for lung cancer patients by Jinbiao Xu, Qiao Ji, Jianxiong Deng, Feng Yu

“…In terms of leukopenia reduction (grades 0–III) and hemoglobin reduction (grades 0–II), the observation group outperformed the control group (P < 0.05). …”
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Androgen action via testicular arteriole smooth muscle cells is important for Leydig cell function, vasomotion and testicular fluid dynamics. by Michelle Welsh, Richard M Sharpe, Lindsey Moffat, Nina Atanassova, Philippa T K Saunders, Sigrid Kilter, Anders Bergh, Lee B Smith

“…Gross reproductive development was normal in SMARKO mice but testis weight was reduced in adulthood compared to control littermates; this reduction was not due to any changes in germ cell volume or to deficits in testosterone, LH or FSH concentrations and did not cause infertility. …”
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Neural mobilisation effects in nerve function and nerve structure of patients with peripheral neuropathic pain: A systematic review with meta-analysis. by Juliana Valentim Bittencourt, Leticia Amaral Corrêa, Maria Alice Mainenti Pagnez, Jéssica Pinto Martins do Rio, Gustavo Felicio Telles, Stephanie Mathieson, Leandro Alberto Calazans Nogueira

“…<h4>Objective</h4>To assess the effects of neural mobilisation on nerve function and nerve structure of patients with peripheral neuropathic pain.…”
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Effects of Replacing Inorganic with Organic Glycinates Trace Minerals on Growth Performance, Gut Function, and Minerals Loss of Juvenile Nile Tilapia by Allan Vinnicius Urbich, Thais Pereira da Cruz, Bruno Wernick, Ibrahim Adeshina, Aline Victoria Sampaio, Giovani Sampaio Gonçalves, Adriana Yuriko Koga Kozu, Leandro Cavalcante Lipinski, Valéria Rossetto Barriviera Furuya, Wilson Massamitu Furuya

“…From the control diet, three diets were elaborated using OTM to supply 100% (OTM100), 75% (OTM75), and 50% (OTM50) of Zn, Mn, and Cu ITM of the control diet, respectively, supplied in the glycinate form. …”
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Retrospective analysis of functional and anatomical changes, the level of intraocular pressure in patients with glaucoma and highgrade myopia during surgical treatment of cataracts by O. V. Krasnozhan, N. S. Lutsenko

“…The frequency of reduction of IOP 1 year after FEC is 70% in patients of the control group, 55% in patients with glaucoma and 10% in patients with high myopia.…”
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A Multicenter, Randomized, Open-Label Study to Compare the Effects of Gemigliptin Add-on or Escalation of Metformin Dose on Glycemic Control and Safety in Patients with Inadequatel... by Hae Jin Kim, Jung Hyun Noh, Min Kyong Moon, Sung Hee Choi, Seung-Hyun Ko, Eun-Jung Rhee, Kyu Yeon Hur, In-Kyung Jeong

“…We aimed to compare efficacy and safety between gemigliptin add-on and escalation of the metformin dose in patients with inadequately controlled type 2 diabetes mellitus (T2DM) despite treatment with metformin and SGLT2 inhibitors. …”
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