Aquificae overcomes competition by archaeal thermophiles, and crowding by bacterial mesophiles, to dominate the boiling vent-water of a Trans-Himalayan sulfur-borax spring. by Nibendu Mondal, Subhajit Dutta, Sumit Chatterjee, Jagannath Sarkar, Mahamadul Mondal, Chayan Roy, Ranadhir Chakraborty, Wriddhiman Ghosh

“…In terms of sequence similarity, a majority of those genes were attributable to phylogenetic relatives of mesophilic bacteria, while functionally they rendered functions such as encoding heat shock proteins, molecular chaperones, and chaperonin complexes; proteins controlling/modulating/inhibiting DNA gyrase; universal stress proteins; methionine sulfoxide reductases; fatty acid desaturases; different toxin-antitoxin systems; enzymes protecting against oxidative damage; proteins conferring flagellar structure/function, chemotaxis, cell adhesion/aggregation, biofilm formation, and quorum sensing. …”
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Differential Effects of Hazardous Drinking on Post-Traumatic Stress Disorder Outcomes Across Two Prolonged Exposure Treatment Formats by Casey L. Straud, Kiara H. Buccellato, Edna B. Foa, Lily A. Brown, Carmen P. McLean, Tabatha H. Blount, Richard P. Schobitz, Bryann B. DeBeer, Joseph Mignogna, Brooke A. Fina, Brittany N. Hall-Clark, Christian C. Schrader, Jeffrey S. Yarvis, Vanessa M. Jacoby, Wyatt R. Evans, Brett T. Litz, Eric C. Meyer, Barbara L. Niles, Stacey Young-McCaughan, Terence M. Keane, Alan L. Peterson

“…The present study is an exploratory, secondary analysis investigating differential effects of prolonged exposure (PE) among those with and without hazardous drinking and whether treatment outcomes varied across these groups as a function of PE format. Data used were from a randomized controlled trial that examined two daily, compressed formats of PE treatment for PTSD (massed and intensive outpatient program) in military personnel and veterans (N = 234). …”
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Early detection to improve outcome in people with undiagnosed psoriatic arthritis: the PROMPT research programme including RCT by Neil McHugh, Laura Bojke, Mel Brooke Turfrey, Rachel Charlton, Myka Ransom, Laura C Coates, Howard Collier, Claire Davies, Emma Dures, Philip Helliwell, Jana James, Anya Lissina, Vishnu B Madhok, Alison L Nightingale, Jonathan Packham, Catherine Smith, Eldon Spackman, Cerys Tassinari, William Tillett, Sarah T Brown

“…Surveillance for undiagnosed psoriatic arthritis generally detects mild cases as measured by physical function. Patients rate pain and fatigue as the most important outcomes. …”
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Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis by Li Cui, Donglei Lu, Sijie Tan, Liquan Cao

“…ART effectively reduced BMI, improved glycemic control, and decreased inflammatory markers through mechanisms involving AMPK and mTOR pathways. …”
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Higher hemoglobin levels are associated with impaired left ventricular global strains in metabolic syndrome: a 3.0 T CMR feature tracking study by Xue Li, Shi-Qin Yu, Zhi-Gang Yang, Bi-Yue Hu, Ke Shi, Jing Wang, Xue-Ming Li, Ge Zhang, Wen-Rong Li, Rong Xu, Yuan Li

“…Targeted monitoring and management of higher Hb levels in MetS patients may help mitigate further deterioration of cardiac function.…”
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Clinical outcomes and outcome predictors of two-year assertive community treatment in Norway: an explorative prospective pre–post study by Torleif Ruud, Maria Lie Selle, Hanne K. Clausen, Kristin S. Heiervang, Sigrun Odden, Hanne Kilen Stuen, Anne Landheim

“…Less improvement in functioning was associated with team fidelity and number of sessions. …”
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Gut Microbiota Alterations in Alzheimer’s Disease: Relation with Cognitive Impairment and Mediterranean Lifestyle by David Mateo, Nerea Carrión, Cristian Cabrera, Luis Heredia, Montse Marquès, Eva Forcadell-Ferreres, Maria Pino, Josep Zaragoza, Alfons Moral, Lluís Cavallé, José M. González-de-Echávarri, Paloma Vicens, José L. Domingo, Margarita Torrente

“…Dysbiosis observed in Spanish AD patients is characterized by reductions in richness and alpha-diversity, alongside alterations in GMB composition, which may be linked to adherence to the ML and cognitive and functionality symptoms.…”
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The use of modern military technologies in the light of the law of weapons and the law of targeting by Behzad Seyfi

“…For example, the customary international rights of coastal state control over the underwater resources of the continental shelf came into being only fifteen years later. …”
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Phosphorus loading and carp disturbance synergistically promote dominance of free-floating macrophytes over submerged plant competitors by Rui Zhou, Dong Luo, Lei Li

“…Reducing P loading and implementing measures to control benthic fish abundance may enhance the resilience of submerged macrophyte-dominated states in shallow lakes and ponds, with additional reductions in N further mitigating the synergistic impacts of nutrient loading on ecosystem stability.…”
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Enhanced motivated behavior mediated by pharmacological targeting of the FGF14/Nav1.6 complex in nucleus accumbens neurons by Nolan M. Dvorak, Paul A. Wadsworth, Guillermo Aquino-Miranda, Pingyuan Wang, Douglas S. Engelke, Jingheng Zhou, Nghi Nguyen, Aditya K. Singh, Giuseppe Aceto, Zahra Haghighijoo, Isabella I. Smith, Nana Goode, Mingxiang Zhou, Yosef Avchalumov, Evan P. Troendle, Cynthia M. Tapia, Haiying Chen, Reid T. Powell, Timothy J. Baumgartner, Jully Singh, Leandra Koff, Jessica Di Re, Ann E. Wadsworth, Mate Marosi, Marc R. Azar, Kristina Elias, Paul Lehmann, Yorkiris M. Mármol Contreras, Poonam Shah, Hector Gutierrez, Thomas A. Green, Martin B. Ulmschneider, Marcello D’Ascenzo, Clifford Stephan, Guohong Cui, Fabricio H. Do Monte, Jia Zhou, Fernanda Laezza

“…Abstract Protein/protein interactions (PPI) play crucial roles in neuronal functions. Yet, their potential as drug targets for brain disorders remains underexplored. …”
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The effect of mild to moderate knee osteoarthritis on gait and three-dimensional biomechanical alterations by Jing Pan, Zhonghao Xie, Huifang Shen, Zhiguan Huang, Xiaohui Zhang, Bagen Liao

“…In the sagittal plane, grade II patients had more significant reductions in knee and ankle ROM. In the coronal plane, grade II patients had less hip and ankle ROM than grade I and controls. …”
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Newborn Screening for Gaucher Disease: Parental Stress and Psychological Burden by Chiara Cazzorla, Vincenza Gragnaniello, Giacomo Gaiga, Daniela Gueraldi, Andrea Puma, Christian Loro, Giada Benetti, Rossana Schiavo, Elena Porcù, Alessandro P. Burlina, Alberto B. Burlina

“…At T0, higher parental stress was assessed in GD1 parents compared to the healthy controls. Subsequently, the parents of GD1 children reported significant reductions in Parental Distress at T1 compared to T0. …”
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Role of Bicarbonate-Sulphate-Alkaline-Earthy Mineral Water, Bentonite Clay Mud and Manual Somatic Stimulation in the Treatment of Osteoarthritis by Giovanni Barassi, Michelina Delli Bergoli, Maurizio Panunzio, Loris Prosperi, Celeste Marinucci, Giuseppe Luigi Matera, Piero Galasso, Pier Enrico Gallenga

“…Osteoarthritis (OA) is a joint chronic pathology, characterized by pain, functional limitation and swelling. It can be seriously disabling, so identifying effective therapies is fundamental for its management. …”
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Machine learning model for reproducing subjective sensations and alleviating sound-induced stress in individuals with developmental disorders by Itsuki Ichikawa, Yukie Nagai, Yukie Nagai, Yasuo Kuniyoshi, Yasuo Kuniyoshi, Yasuo Kuniyoshi, Makoto Wada

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Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens by Karthik Hullahalli, Katherine G. Dailey, Ryan Acbay, Masataka Suzuki, George I. Balazs, Matthew K. Waldor

“…Understanding how innate immune responses are controlled during infection is important for developing new approaches to dampen excessive inflammation. …”
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Rapeseed Green Manure Coupled with Biochar and Vermicompost Enhances Soil Aggregates and Fungal Communities in Gleyed Paddy Fields by Zhenhao Zhu, Shihong Gao, Yuhao Zhang, Guohan Si, Xiangyu Xu, Chenglin Peng, Shujun Zhao, Wei Liu, Qiang Zhu, Mingjian Geng

“…The GMB strategy mitigates reductive stress, enhances nutrient availability, and activates microbial functionality. …”
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Corticolimbic Structural Deficits in Violent Patients with Schizophrenia by Maria Athanassiou, Alexandre Dumais, Inès Zouaoui, Alexandra Fortier, Luigi de Benedictis, Olivier Lipp, Andràs Tikàsz, Stéphane Potvin

“…Future research should aim to investigate potential functional interactions at a network level to gain a deeper understanding of the neurobiological underpinnings of violent behaviors in this population.…”
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Validation of Strategic Memory Advanced Reasoning Training as an efficient and effective approach to treating warfighters with persistent cognitive complaints associated with mild... by Andrew J. Darr, Andrew J. Darr, Andrew J. Darr, Angela Basham, Angela Basham, Angela Basham, Jessica L. Ryan, Melissa Caswell, Melissa Caswell, Melissa Caswell, Juan Lopez, Juan Lopez, Juan Lopez, Jennifer Zientz, Erin Venza, Ida Babakhanyan, Ida Babakhanyan, Ida Babakhanyan, Sandra Chapman, Jason M. Bailie, Jason M. Bailie, Jason M. Bailie

“…Additionally, treatment improved patient perceived functionality (KBCI) from T1 to T2 and these gains remained stable at T3 (p < 0.001, ηp2 = 0.377). …”
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Outcomes of transcatheter aortic valve replacement in younger low-risk patients: a comprehensive meta-analysis of efficacy and safety by António Rocha de Almeida, António Rocha de Almeida, António Rocha de Almeida, Maria Rita Lima, Maria Rita Lima, Daniel A. Gomes, Renato Fernandes, Eduardo Infante Oliveira, Eduardo Infante Oliveira, Pedro Araújo Gonçalves, Pedro Araújo Gonçalves, Rui Campante Teles, Rui Campante Teles, Manuel de Sousa Almeida, Manuel de Sousa Almeida, Lino Patrício

“…Secondary endpoints included all-cause mortality, disabling stroke, atrial fibrillation (AF), permanent pacemaker implantation (PPI), bleeding, functional class (NYHA), and quality-of-life (KCCQ score) improvements.ResultsFour RCTs were included with 4,252 patients (2,125 TAVI and 2,127 SAVR). …”
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A first-in-human, prospective pilot trial of umbilical cord-derived mesenchymal stem cell eye drops therapy for patients with refractory non-Sjögren's and Sjögren's syndrome dry ey... by Di Zhang, Taige Chen, Qi Liang, Xuebing Feng, Jiaxuan Jiang, Zeying Chen, Yun Tang, Yiran Chu, Bin Wang, Kai Hu

“…Secondary assessments focused on the evaluation of lipid layer, meibomian gland function, and bulbar conjunctival redness. Safety was monitored by recording adverse events (AEs) throughout the study. …”
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