Lipid liquid-crystalline nanoparticles as a suitable platform for accommodating sensitive membrane proteins: monitoring the activity of HMG-CoA reductase by Michalina Zaborowska-Mazurkiewicz, Ewa Nazaruk, Renata Bilewicz

“…The nanostructured lipid liquid-crystalline (LLC) nanoparticles known as hexosomes are selected as a convenient nanocontainer for the redox–active protein for real-time monitoring of its functions in the bulk of the solution and point to the applicability of the proposed platform in the evaluation of therapeutic functions of the protein by standard physicochemical methods. …”
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Unveiling the role of pentagonal topological defects in lignocellulose-derived self-assembled N/O co-doped micro-mesoporous biochar for enhanced CO₂ adsorption by Lingru Zeng, Shaoyi Zeng, Ping Liu, He Li, Wei Chen, Kunquan Li

“…Here, N/O coupled topological defect co-doped biochars (NWBCs-T) were successfully synthesized via self-assembly temperature-controlled carbonization/annealing within 500–900 °C from red bayberry pits. …”
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Slow-Paced Breathing Intervention in Healthcare Workers Affected by Long COVID: Effects on Systemic and Dysfunctional Breathing Symptoms, Manual Dexterity and HRV by Marcella Mauro, Elisa Zulian, Nicoletta Bestiaco, Maurizio Polano, Francesca Larese Filon

“…Non-invasive vagus nerve stimulation using slow-paced breathing (SPB) could stimulate both central nervous system areas and parasympathetic autonomic pathways, leading to neuromodulation and a reduction in inflammation. The aim of the present study was to evaluate physical, cognitive, emotional symptoms, executive functions and autonomic cardiac modulation after one month of at-home slow breathing intervention. …”
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How Three Decades of Forestation Has Impacted Forest Fragmentation in Southern China by Chen Mao, Xiaowei Tong, Martin Brandt, Yuemin Yue, Wenmin Zhang, Jun Lu, Ke Huang, Kelin Wang

“…Furthermore, we found that the average level of cooling effects in areas with increased forest cover of less than 40% is heavily dominated by forest fragmentation, whereas the cooling effects are primarily controlled by changes in forest cover. These findings underscore the role of human disturbance in driving forest fragmentation, which in turn affects the functioning of forest ecosystems. …”
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Formation of porous structure in paramylon esters via supercritical CO₂ by Seisuke Ata, Takumi Ono, Motonari Shibakami

“…Furthermore, thermal conductivity measurements revealed reductions of up to 20%. Intriguingly, substantial decreases in thermal conductivity were observed even at low foaming ratios, achieved through precise control of the porous structure.…”
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Deletion of the Human Cytomegalovirus US2 to US11 Gene Family Members Impairs the Type-I Interferon Response by Inessa Penner, Nadine Krämer, Julia Hirsch, Nicole Büscher, Hanno Schmidt, Bodo Plachter

“…ISGs encode proteins with antiviral functions, such as inhibiting viral replication, promoting cell death of infected cells and enhancing immune responses. …”
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Eco-Friendly Synthesis of Cerium Oxide Nanoparticles from <i>Lycium cooperi</i> by Jhonathan Castillo-Saenz, Jorge Salomón-Carlos, Ernesto Beltrán-Partida, Benjamín Valdez-Salas

“…Furthermore, we detected the presence of stabilizing functional groups from <i>L. cooperi</i>, which, after a controlled annealing process, resulted in a band gap energy of 3.9 eV, which was optimal for the CeO₂-NPs. …”
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Research on Design and Energy-Saving Performance of Gate Rudder by Chunhui Wang, Qian Gao, Lin Li, Feng Gao, Zhiyuan Wang, Chao Wang

“…As a novel energy-saving and maneuvering device for ships, the gate rudder system (GRS) functions similarly to an accelerating duct. While providing additional thrust, its independently controllable rudder blades on either side of the propeller also enhance ship maneuverability. …”
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Transcriptional regulation of GmNAC3-mediated drought stress tolerance in soybean by Nooral Amin, Liu Lu, Faizur Rehman, Muhammad Imran, Gai Yuhong, Piwu Wang, Wei Jian

“…Among the 179 NAC TFs encoded in the soybean genome, several are differentially expressed under stress conditions; however, the functional role of GmNAC3 in drought tolerance remains largely unknown. …”
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Systematic Literature Review of the Efficacy and Safety of Khan Kinetic Treatment for Neck and Back Pain by Yazid Maghrabi, Lamair Albakri, Hana Alsebaeyl, Saleh Baeesa

“…While some studies suggest benefits in pain reduction and functional improvement, methodological limitations and small sample sizes undermine generalizability. …”
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Comprehensive Management Approaches for Acute Distal Radioulnar Joint Instability Post distal End Radius Fracture by Anteshwar Birajdar, Sushant Kumar, Mukesh Phalak, Tushar Chaudhari, Damarla Meghana

“…The key takeaway from the article is that TFCC repair may not be essential, with K-wire stabilization providing better range of motion and cast immobilization offering stronger grip, but further large-scale controlled trials are required to fully assess these treatment options in terms of patient satisfaction and functional outcomes. …”
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Impact of early β-blocker use on the incidence of sepsis and clinical outcomes following cardiac surgery: a retrospective cohort study by Chen Yin, Chengjian Guan, Qianli Ma, Shaotong Zhang, Qian Chen, Bing Xiao

“…Sensitivity analyses using Fine-Gray competing risk models and cumulative incidence functions were performed. Subgroup analyses explored heterogeneity of treatment effects, and metoprolol was further stratified by dose to assess dose-response relationships.ResultsA total of 3,154 patients treated with β-blocker and 5,220 controls were included. …”
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Minimally invasive pouch technique with leukocyte platelet rich fibrin compared to non-invasive hyaluronic acid injection in reconstruction of interdental papilla in esthetic zone:... by Aya Alleithy, Hala Abuel-Ela, Susan Sarhan

“…Abstract Background Interdental papilla deficiency is of high concern from the esthetic and functional perspectives. Several invasive approaches have been reported for interdental papilla reconstruction. …”
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Up-regulation of microRNA-190b plays a role for decreased IGF-1 that induces insulin resistance in human hepatocellular carcinoma. by Tzu-Min Hung, Cheng-Maw Ho, Yen-Chun Liu, Jia-Ling Lee, Yow-Rong Liao, Yao-Ming Wu, Ming-Chih Ho, Chien-Hung Chen, Hong-Shiee Lai, Po-Huang Lee

“…This study provides a novel miRNA-mediated regulatory mechanism for controlling IGF-1 expression in HCC and elucidates the biological relevance of this interaction in HCC.…”
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Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination. by Debora Bogani, Pam Siggers, Rachel Brixey, Nick Warr, Sarah Beddow, Jessica Edwards, Debbie Williams, Dagmar Wilhelm, Peter Koopman, Richard A Flavell, Hongbo Chi, Harry Ostrer, Sara Wells, Michael Cheeseman, Andy Greenfield

“…Sex determination in mammals is controlled by the presence or absence of the Y-linked gene SRY. …”
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Combined effect of prefrontal transcranial direct current stimulation and a working memory task on heart rate variability. by Stevan Nikolin, Tjeerd W Boonstra, Colleen K Loo, Donel Martin

“…Bifrontal tDCS was administered for 15 minutes at 2mA to 20 participants in a sham controlled, single-blind study using parallel groups. …”
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Effect of eicosapentaenoic acid on innate immune responses in Atlantic salmon cells infected with infectious salmon anemia virus by Ingrid Holmlund, Samira Ahmadi, Bente Ruyter, Tone-Kari Østbye, Marta Bou, Tor Gjøen

“…Cell death via ferroptosis may therefore be a mechanism for controlled cell death and thus reduction of virus replication when there are enough polyunsaturated fatty acids (PUFAs) in the membrane.…”
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Reduced neural suppression at occipital cortex in subthreshold depression by Jinhui Li, Yuheng Tan, Zixin Zheng, Chunliang Feng, Wenjie Fang, Xiaodan Huang, Song Lin, Kwok-Fai So, Lu Huang, Chaoran Ren, Qian Tao

“…The current study recruit young adults with SD and demographically matched healthy controls (HC). Experiment 1 utilized a series of psychophysical tasks in a large sample (n = 95), and Experiment 2 used a functional magnetic resonance imaging (fMRI) approach in a medium sample (n = 63). …”
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Crosstalk between neuroendocrinology and follicular dynamism: the mare experimental model for reproductive “aging” in women by Esterina Fazio

“…Follicular dynamism is characterised by three functional moments whose endocrine mechanisms dictate their physiological sequence of events: Recruitment, selection and dominance. …”
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Baricitinib-associated changes in global gene expression during a 24-week phase II clinical systemic lupus erythematosus trial implicates a mechanism of action through multiple imm... by Daniel J Wallace, Thomas Dörner, Stephanie de Bono, Robert J Benschop, Ernst R Dow, Damiano Fantini, Richard E Higgs, Guilherme Rocha, Brenda Crowe, Nicole L Byers, Maria E Silk, Robert W Hoffman

“…At baseline, serum cytokines IFN-α, IFN-γ, interleukin (IL)-12p40 and IL-6 were measurable and elevated above healthy controls. Treatment with baricitinib significantly decreased serum IL-12p40 and IL-6 cytokine levels at week 12, which persisted through week 24.Conclusion Baricitinib treatment induced significant reduction in the RNA expression of a network of genes associated with the JAK/STAT pathway, cytokine signalling and SLE pathogenesis. …”
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