Spatial transcriptomic characteristics of gastric cancer in young and the expression and role of TMEM176B in gastric cancer cells by Zhenhua Jiang, Yongfeng Wang, Chi Zhang, Shuangyin Han

“…ST-seq was performed to obtain the transcript expression levels at different spatial locations. After quality control, normalization, standardization, clustering, dimensionality reduction, and cell-type prediction analyses were carried out to identify the DEGs. …”
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Beneficial Effects of <i>Lactobacillus delbrueckii subsp. lactis</i> N102 and <i>Lactobacillus sakei</i> H1-5 Added as Starter Strains on the Metabolome, Safety and Quality of Dry-... by Yushan Jiao, Min Cai, Wensheng Tang, Zhengkai Wang, Yingli Liu

“…The co-inoculation strategy demonstrated synergistic effects through (1) accelerated acidification (pH 5.3 by day 6); (2) enhanced textural properties (significantly increased hardness and elasticity vs. control); (3) optimized water distribution (free water reduced to 0.56% with 64.73% immobilized water); and (4) a significant reduction in sodium nitrite residues (70% decrease) and complete elimination of phenylethylamine (total biogenic amines: 702.94 mg/kg). …”
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New horizons in microbial fuel cell technology: applications, challenges, and prospects by Tikam Chand Dakal, Nitesh Singh, Amandeep Kaur, Prabhsangam Kaur Dhillon, Janvi Bhatankar, Ramovatar Meena, Rakesh Kumar Sharma, B. R. Gadi, Bikram Sen Sahu, Asmita Patel, Buddha Singh, Kajal Kumari

“…This review provides a detailed assessment of the fundamental and functional components of MFCs. These components include the anode, which facilitates the oxidation of organic matter, and the cathode, where the reduction of oxygen or other electron acceptors occurs. …”
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Phα1β interaction with the Kv11.1 potassium channel in HEK293 cells transfected with the human ERG channel by João B. Calixto, Adara Aurea dos Santos, Juliano Ferreira, Alessandra Hubner Souza, Célio José de Castro Junior, Marcus Vinicius Gomez

“…The assay involved testing the effects of Phα1β alongside the well-established hERG potassium channel blocker dofetilide, which served as a positive control. The viability of HEK-293 cells was assessed using the colorimetric MTT reduction test (3-(4, dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide), whereby viable cells reduce the MTT salt, forming a formazan complex within their mitochondria, as previously described. …”
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Yeast hydrolysate and exercise ameliorate high-fat diet-induced obesity in C57BL/6 mice by Nari Kim, Yejin Ahn, Eun-Jin Jung, Hyeon-Son Choi, Hyung Joo Suh, Yeok Boo Chang

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Dehydroacteoside rejuvenates senescence via TVP23C-CDRT4 regulation by Yoo Jin Lee, Eun Seon Song, Yun Haeng Lee, Kyeong Seon Lee, Byeonghyeon So, Ji Ho Park, Jee Hee Yoon, Duyeol Kim, Minseon Kim, Hyung Wook Kwon, Youngjoo Byun, Ki Yong Lee, Joon Tae Park

“…Dehydroacteoside restored mitochondrial function, thereby reducing mitochondrial ROS generated by inefficient electron transport. …”
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Steroids combined with anticoagulant in acute/subacute severe cerebral venous thrombosis by Shimin Hu, Yaqin Gu, Tingyu Zhao, Kaiyuan Zhang, Jingkai Li, Chen Zhou, Haiqing Song, Zhi Liu, Xunming Ji, Jiangang Duan, Ting Gao

“…A reduction in serum inflammatory marker levels during hospitalization positively correlated with improvements in functional outcomes (P <0.05). …”
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Neuroprotective properties of GABA and its derivatives in diabetic encephalopathy in old animals by I. N. Tyurenkov, D. A. Bakulin, A. V. Smirnov, M. R. Ekova, A. I. Bisinbekova, G. L. Snigur, Yu. I. Velikorodnaya, E. I. Morkovin, D. V. Verkholyak, O. S. Vasilyeva

“…After the treatment, an oral glucose tolerance test and a set of behavioral tests aimed at studying sensory-motor (Open Field, Adhesion test, Rotarod) and cognitive functions (New Object Recognition and Morris Water Maze), as well as the functional state evaluation of the endothelium were performed. …”
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Quantification of the Role of Teupol^® 25P and Graminex^® G96 Compared to Hexanic Extract of <i>Serenoa repens</i> in Patients Affected by Lower Urinary Tract S... by Yazan Al Salhi, Damiano Graziani, Andrea Fuschi, Fabio Maria Valenzi, Manfredi Bruno Sequi, Paolo Pietro Suraci, Alice Antonioni, Onofrio Antonio Rera, Cosimo De Nunzio, Riccardo Lombardo, Paolo Benanti, Giuseppe Candita, Eleonora Rosato, Filippo Gianfrancesco, Giorgio Martino, Giovanni Di Gregorio, Luca Erra, Giorgio Bozzini, Antonio Carbone, Antonio Luigi Pastore

“…No differences in erectile function (IIEF-5) or adverse events were observed. …”
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Dynamic Error Modeling and Predictive Compensation for Direct-Drive Turntables Based on CEEMDAN-TPE-LightGBM-APC Algorithm by Manzhi Yang, Hao Ren, Shijia Liu, Bin Feng, Juan Wei, Hongyu Ge, Bin Zhang

“…Accurate error prediction and compensation technology represent a critical prerequisite for achieving continuous error compensation and predictive control in direct-drive turntables, making research on positioning error modeling, prediction, and compensation of vital importance. …”
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Effects of Pilates Exercises Versus Conventional Exercises Among Post-Menopausal Women Suffering From Non-Specific Low Back Pain, By Improving Lumbar Flexibility, Endurance, and Qu... by C. Nageswari, N. Meena

“…It is a leading cause of pain, functional limitations, and reduced quality of life. …”
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Efficacy and Safety of Lumasiran in Patients With Primary Hyperoxaluria Type 1: Results from a Phase III Clinical Trial by Jeffrey M. Saland, John C. Lieske, Jaap W. Groothoff, Yaacov Frishberg, Hadas Shasha-Lavsky, Daniella Magen, Shabbir H. Moochhala, Eva Simkova, Martin Coenen, Wesley Hayes, Julien Hogan, Anne-Laure Sellier-Leclerc, Richard Willey, John M. Gansner, Sally-Anne Hulton

“…A 6-month double-blind placebo-controlled period is followed by an extension period (≤54 months; all patients receive lumasiran). …”
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Integrated metabolomic-lipidomic profiling reveals novel biomarkers and therapeutic targets for alcohol use disorder with cognitive impairment by Li Shi, Li Shi, Li Shi, Xiaofang Chen, Bojie Zhou, Bojie Zhou, Shanghao Yang, Shanghao Yang, Qinglin Ou, Qinglin Ou, Xuhui Zhou, Xuhui Zhou

“…Cognitive function was assessed using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). …”
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Comparison of low-pressure and standard-pressure pneumoperitoneum laparoscopic cholecystectomy in patients with cardiopulmonary comorbidities: a double blinded randomized clinical... by Feng Tian, Xiaowei Sun, Yang Yu, Ning Zhang, Tao Hong, Lu Liang, Bihui Yao, Lei Song, Changhong Pei, Yu Wang, Wenlong Lu, Qiang Qu, Junchao Guo, Taiping Zhang, Xiaodong He

“…Surgical safety variables, patient recovery, pulmonary function parameters, and surgeon comfort were also compared between groups. …”
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A click-based electrocorticographic brain-computer interface enables long-term high-performance switch scan spelling by Daniel N. Candrea, Samyak Shah, Shiyu Luo, Miguel Angrick, Qinwan Rabbani, Christopher Coogan, Griffin W. Milsap, Kevin C. Nathan, Brock A. Wester, William S. Anderson, Kathryn R. Rosenblatt, Alpa Uchil, Lora Clawson, Nicholas J. Maragakis, Mariska J. Vansteensel, Francesco V. Tenore, Nicolas F. Ramsey, Matthew S. Fifer, Nathan E. Crone

“…Abstract Background Brain-computer interfaces (BCIs) can restore communication for movement- and/or speech-impaired individuals by enabling neural control of computer typing applications. Single command click detectors provide a basic yet highly functional capability. …”
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Beta-hydroxy-beta-methylbutyrate (HMB) improves daily activity and whole-body protein metabolism in Duchenne muscular dystrophy dogs: a pilot study by Peter P. Nghiem, Alexis M. Rutledge, Kyle Tehas, Corine Kaderli, Meredith Poling, Sidney Arnim, Vitaliy Dernov, Celine van Sas, Macie L. Mackey, Gabriella A. M. ten Have, Mariëlle P. K. J. Engelen, Nicolaas E. P. Deutz

“…Six DMD dogs were administered 3 g daily of HMB or placebo for 28 days according to a randomized, placebo-controlled, double-blinded crossover design. We measured pre- and post-intervention daily activity, biochemistry markers, and whole-body amino acid kinetics. …”
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Conversion from calcineurin inhibitors to sirolimus of recipients with chronic kidney graft disease grade iii for a period 2003-2011 by Ignjatović Ljiljana, Hrvačević Rajko, Jovanović Dragan, Kovačević Zoran, Vavić Neven, Rabrenović Violeta, Tomić Aleksandar, Aleksić Predrag, Drašković-Pavlović Biljana, Dujić Aleksandar, Karan Željko, Maksić Đoko

“…During the regular outpatient controls we followed graft function through the serum creatinine and glomerular filtration rate (GFR), proteinuria, lipidemia and side effects. …”
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Ambient ammonium exposure is associated with physical dysfunction in older adults in China by JiaHao Shi

“…These findings underscore the necessity for specific environmental strategies focused on ammonia reduction to alleviate age-related functional deterioration and foster healthy aging.…”
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The effects of various nutritional supplements in patients with chronic obstructive pulmonary disease: a network meta-analysis by Jia Zeng, Jing Cheng, Liangdong Zhu, Sufang Tang

“…Methods We searched PubMed, Embase, Cochrane Library, and Web of Science databases for randomized controlled trials on nutritional supplements for COPD patients, with the search updated to March 24, 2025. …”
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Blunted cardiovascular responses in individuals with type 2 diabetes and hypertension during cold and heat exposure by Mojdeh Rafieian, Erlend Hoftun Farbu, Anje Christina Höper, Anje Christina Höper, Rasmus Valtonen, Rasmus Valtonen, Henna Hyrkäs-Palmu, Juha Perkiömäki, Juha Perkiömäki, Craig Crandall, Jouni J. K. Jaakkola, Jouni J. K. Jaakkola, Tiina Maria Ikäheimo, Tiina Maria Ikäheimo

“…Central and brachial blood pressure (BP), heart rate (HR), and skin blood flow were measured before, during, and after the exposure.ResultsDuring cold exposure, subjects with T2D exhibited a smaller increase in central (14 (CI 95%:3, 23) vs. 43 (CI 95%:32, 53) mmHg, p &lt; 0.05) and brachial systolic BP (12 (CI 95%:1, 22)) vs. 40 (CI 95%:30, 51) mmHg, p &lt; 0.05) compared to controls. The corresponding reduction in HR in the cold was also less in T2D compared to controls (5 (CI 95%: 10, 0.02) vs. 9 (CI 95%: 14, −4) bpm, p &lt; 0.05). …”
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