N6-methyladenosine RNA base modification regulates NKG2D-dependent and cytotoxic genes expression in natural killer cells by Raghda A. Elsabbagh, Ghada Abdelhady, Doris Urlaub, Mina Sandusky, Ola Khorshid, Mohamed Z. Gad, Khaled Abou-Aisha, Carsten Watzl, Mona Rady

“…This study aims to assess m6A levels in transcripts involved in the NKG2D cytotoxicity signaling pathway in NK cells of BC patients compared to controls and find out its impact on mRNA levels. Additionally, it evaluates how deliberately altering m6A levels in NK cells affects mRNA and protein expression of NKG2D pathway genes and NK cell functionality. …”
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Sirtuin 1 expression in elderly patients with type 2 diabetes mellitus by Mohamed M. M. Hassaan, Imam M. Esmayel, Mayada M. Mousa, Samia Hussein, Ahmed K. Y. Alkolaly, Batoul A. Hegazy, Rodalia M. Makhlouf

“…SIRT7 is present in the nucleoli and controls RNA polymerase I. The SIRT1 gene is present on chromosome 10 at the 10q21.3 locus. …”
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Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia. by Rozana Santos Teixeira, Regina Terse-Ramos, Tatiane Anunciação Ferreira, Vinícius Ramos Machado, Marya Izadora Perdiz, Isa Menezes Lyra, Valma Lopes Nascimento, Ney Boa-Sorte, Bruno B Andrade, Ana Marice Ladeia

“…<h4>Conclusions</h4>Children and adolescents with SCA exhibit impaired endothelial function. Reductions in FMD values are associated with ACS. …”
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Strawberry dietary intervention influences diversity and increases abundances of SCFA-producing bacteria in healthy elderly people by Franziska Meiners, Bernd Kreikemeyer, Patrick Newels, Ingmar Zude, Michael Walter, Alexander Hartmann, Daniel Palmer, Georg Fuellen, Israel Barrantes

“…Participants in five groups consumed varying amounts of strawberries, freeze-dried strawberries, and capers in olive oil over 10 weeks as part of a randomized controlled trial. 16S rRNA sequencing was used to analyze differences in microbial composition, diversity, phenotypes, differential abundance, and functional pathways. …”
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ORUS: Ultrasonic Ostemodeling for Body Contouring by Jesua Emmanuel Avilez, MD, Daniel Rodolfo Noriega, MD, MS, Cesar Edwin Martínez, MD, Jonathan Mauricio Quisilema, MD

“…An attractive waist–hip ratio leads to a favorable aesthetic appearance in women and can be achieved through the osteo remodelación ultrasónica simplificada (ORUS) technique, which consists of the controlled fracture of the floating ribs through a small incision in the back based on an umbrella’s functioning (open-semiclosed). …”
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Deprescribing Antihypertensive Drugs in Patients of Older Age Groups by O. D. Ostroumova, M. S. Cherniaeva, D. A. Sychev

“…In this regard, in recent years, the possibility/necessity of a planned and controlled process of dose reduction, drug withdrawal or replacement, if this drug can be harmful and/or does not bring benefits (deprescribing), has attracted attention. …”
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Effectiveness of movement representation techniques in non-specific shoulder pain: a systematic review and meta-analysis by Nuray Alaca, Ali Ömer Acar, Sergen Öztürk

“…MRT demonstrated a large effect size for pain reduction (high heterogeneity, I2 = 85.2%, Hedges’g = 1.324, 95% CI = 0.388–2.260, P = 0.006), functional improvement (moderate heterogeneity, I2 = 70.82%, Hedges’g = 1.263, 95% CI = 0.622–1.904, P < 0.001), and reduction of pain-related fear (moderate heterogeneity, I2 = 70.86%, Hedges’g = 0.968, 95% CI = 0.221–1.716, P < 0.001). …”
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Efficacy of a Soft Wearable Robot for Hip Assistance in Chronic Stroke Patients: A Randomized Crossover Trial by Seung-Hyeon Han, Sanguk Choi, Chanyoung Ko, Jong Weon Lee, Kyoungchul Kong, Dong-Wook Rha, Deog Young Kim

“…This research highlights the potential of SWR technology to enhance functional mobility and autonomy in stroke survivors. …”
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Neuroimaging differences between chronic migraine with and without medication overuse headache: a 7 Tesla multimodal MRI study by Yin Sun, Longteng Ma, Song Wang, Caohui Duan, Xinyu Wang, Xiangbing Bian, Shuqing Wang, Deqi Zhai, Siyuan Xie, Shuhua Zhang, Yingyuan Liu, Xiaoxue Lin, Ruobing Wang, Xiu Liu, Shengyuan Yu, Xin Lou, Zhao Dong

“…These results highlight the significant impact of medication overuse on brain structure and function, shedding light on the mechanisms of migraine chronification.…”
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Unlocking Therapeutic Potential: Enhanced shRNA Delivery with Tat Peptide in the Human Respiratory Syncytial Virus Treatment by Saeid Amiri Zadeh Fard, Haniyeh Abuei, Abbas Behzad Behbahani, Gholamreza Rafiei Dehbidi, Farahnaz Zare, Maryam Nejabat, Alireza Safarpour, Ali Farhadi

“…The cytotoxicity of ribavirin, shRNA constructs, and control agents was assessed using the MTT assay. The transfection efficiency of Tat peptide-mediated shRNA delivery with that of lipofectamine 3000™ were compared. …”
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Stem cell-derived exosome delivery systems for treating atherosclerosis: The new frontier of stem cell therapy by Hassan Tariq, Syeda Zunaira Bukhari, Ruibing An, Jian Dong, Ayesha Ihsan, Muhammad Rizwan Younis

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EPA-lactone derivative, 5,6-diHETE lactone, improves pulmonary arterial hypertension in a monocrotaline-induced model by Karthik Dhananjayan, Karthik Dhananjayan, Offir Ertracht, Shaul Atar, Shaul Atar, Shaul Atar, Alejandro Livoff, Alejandro Livoff, Mona Shehadeh, Andrea Szuchman-Sapir, Andrea Szuchman-Sapir

“…Finally, all animals were sacrificed upon functional, hematological, and histological evaluations.ResultsEPA-L administration (i.v.) significantly reduced mean pulmonary arterial pressure (p &lt; 0.05), echocardiographic pulmonary artery time-to-peak (p &lt; 0.05), arterioles intimal-media thickness (p &lt; 0.05) compared to the MCT group. …”
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Effect of LED spectrum on the regulation of appetite-related hormones in the digestive tract of red seabream (Pagrus major) by Si-Chan Kim, Ji-Sung Moon, Josel Cadangin, Bo-Hyun Joo, Han-Sik Kim, Sang-Woo Hur, Youn Hee Choi

“…Light is an external factor that stimulates the neuroendocrine system through the hypothalamus and controls hormonal regulation in fish. Specifically, various light wavelength can influence feeding behavior and feed digestion by regulating the expression of key hormones that control appetite and digestive functions or processes. …”
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Biochemical composition of refluxate in saliva and gastric juice in patients with physiological cardia insufficiency and hiatal hernias under martial law conditions by O.M. Babii, A.M. Halinska, N.V. Prolom, О.О. Halinskyi

“…A significant increase in bile acid concentration was observed in the saliva of MP, which is a marker of aggressive reflux, whereas in NMP, pH levels changed more prominently, along with a reduction in pepsin. NOx content in MP with HH type II significantly exceeded control values, indicating active inflammatory processes. …”
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Influence of caffeic acid and Bacillus coagulans supplementation on growth, digestive enzymes, immune response, and antioxidant gene expression in common carp (Cyprinus carpio) and... by Seyedeh Shiva Alavinejad, Mehdi Soltani, Seyed saeed Mirzargar, Poulin Shohreh, Ali Taherimirghaed

“…Furthermore, a significant reduction in mortality was observed in treatment groups compared to CD under the A. hydrophila challenge. …”
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VERTICAL DIMENSION OF OCCLUSION CHARACTERISTICS IN PATIENTS WITH DIFFERENT TYPES OF MALOCCLUSIONS BY THE SHIMBASHI INDEX IN THE AGE ASPECT by O.M. Makarova, V.D. Kuroiedova, Y.V. Rud

“…The morphometric investigation of control-diagnostic models of jaws of 300 orthodontic patients in different ages was performed. …”
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Nano-Biochar Enhanced Adsorption of NO₃⁻-N and Its Role in Mitigating N₂O Emissions: Performance and Mechanisms by Weimin Xing, Tao Zong, Yidi Sun, Wenhao Fang, Tong Shen, Yuhao Zhou

“…The NO₃⁻-N adsorption experiments included two treatments: bulk BC and NBC; the N₂O emissions experiments involved three treatments: a no-biochar control, BC, and NBC. N₂O emissions experiments were incorporated into the soil at mass ratios of 0.3%, 0.6%, 1%, and 3%. …”
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Features of the dynamics of serum C-reactive protein and IL-6 concentrations in case of experimental carrageenan-induced inflammation of temporomandibular joints by D.O. Kovalchuk, N.M. Savielieva, A.Yu. Nikonov, N.M. Breslavets

“…The temporomandibular joint is a complex anatomical and functional structure, consisting of the mandibular condyle, mandibular fossa, articular tubercle of the temporal bone, intra-articular disc, and joint capsule. …”
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Transcranial Doppler sonography follow-up study in mild vascular cognitive impairment. by Mariagiovanna Cantone, Manuela Pennisi, Giuseppe Lanza, Raffaele Ferri, Francesco Fisicaro, Francesco Cappellani, Emanuele David, Vito Nicosia, Klizia Cortese, Giovanni Pennisi, Valentina Puglisi, Rita Bella

“…<h4>Conclusions</h4>Notwithstanding some limitations, such as the lack of a control group and neuroimaging data at follow-up, TCD may contribute to the early detection, monitoring, and management of VCI patients at risk for dementia. …”
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Targeting necroptosis in MCF-7 breast cancer cells: In Silico insights into 8,12-dimethoxysanguinarine from Eomecon Chionantha through molecular docking, dynamics, DFT, and MEP stu... by Maram B Alhawarri, Mohammad G Al-Thiabat, Amit Dubey, Aisha Tufail, Katreen Banisalman, Ghazi A Al Jabal, Eman Alkasasbeh, Esra'a Ibrahim Al-Trad, Bilal Harieth Alrimawi

“…Principal component analysis (PCA) indicated a significant reduction in MLKL's conformational space upon SG-A binding, implying enhanced stabilization. …”
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