Aryl hydrocarbon receptor signaling in male fertility: Protective role of resveratrol and disruptive effects of CH223191 in adult male rats by Ghadeer Sabah Bustani, Hasan Falah Kashef Alghetaa

“…Background and Aim: The aryl hydrocarbon receptor (AhR) plays a pivotal role in spermatogenesis through its regulatory functions in redox balance and gene expression. This study aimed to investigate the effects of resveratrol (RES), a polyphenolic AhR modulator, and CH223191, a selective AhR antagonist, on male reproductive function in rats by assessing sperm quality, oxidative stress, testicular histopathology, and AhR gene expression. …”
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Methyl-CpG-binding (SmMBD2/3) and chromobox (SmCBX) proteins are required for neoblast proliferation and oviposition in the parasitic blood fluke Schistosoma mansoni. by Kathrin K Geyer, Sabrina E Munshi, Helen L Whiteland, Narcis Fernandez-Fuentes, Dylan W Phillips, Karl F Hoffmann

“…Until a vaccine is developed, this neglected infectious disease is primarily controlled by praziquantel, a drug with a currently unknown mechanism of action. …”
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Increased Insulin Secretion and Glucose Effectiveness in Obese Patients with Type 2 Diabetes following Bariatric Surgery by Roberto Visentin, Katrine Brodersen, Bjørn Richelsen, Niels Møller, Chiara Dalla Man, Andreas Kristian Pedersen, Jan Abrahamsen, Jens Juul Holst, Michael Festersen Nielsen

“…Eight healthy subjects served as metabolic controls. Plasma glucose, insulin, C-peptide, GLP-1, and GIP were measured during each OGTT. …”
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Tracking Long-Term Ozone Pollution Dynamics in Chinese Cities with Meteorological and Emission Attribution by Hongrui Li, Xiaoyong Liu, Zijian Liu, Mengyang Li, Tong Wu, Peicheng Li, Peng Zhou

“…Although China has achieved substantial reductions in particulate matter pollution, continually rising ground-level ozone now constitutes the primary challenge to further air-quality improvements. …”
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Characterization of the salivary microbiome in healthy individuals under fatigue status by Xianhui Peng, Na Han, Yanan Gong, Lihua He, Yanli Xu, Di Xiao, Tingting Zhang, Yujun Qiang, Xiuwen Li, Wen Zhang, Jianzhong Zhang

“…This study aimed to delineate the structural and functional alterations in the salivary microbiome of healthy individuals undergoing physiological fatigue compared to energetic controls, and to explore its potential as a biomarker for fatigue status.MethodsA cohort of 7 healthy individuals experiencing acute physiological fatigue (induced by prolonged study and confirmed via electroencephalography; Fatigue group, FTG) and 63 energetic healthy controls (Energetic group, ENG) were enrolled. …”
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Investigating Neurometabolite Changes in Response to Median Nerve Stimulation by Mairi S. Houlgreave, Katherine Dyke, Adam Berrington, Stephen R. Jackson

“…ABSTRACT Background Rhythmic median nerve stimulation (MNS) at 10 Hz has been shown to cause a substantial reduction in tic frequency in individuals with Tourette syndrome. …”
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The Impact of a Plant-Based Diet on Inflammatory Symptoms In Rheumatoid Arthritis: A Review by Justyna Moszkowicz, Tomasz Ufniarski, Aleksandra Piech, Martyna Grodzińska, Maria Kleczkowska, Karol Poplicha, Piotr Sobkiewicz, Karolina Pasierb, Patrycja Kardasz, Bartłomiej Siuzdak, Marta Jutrzenka

“…A systematic analysis of clinical trials and observational studies reveals that vegan, vegetarian, and plant-forward dietary patterns contribute to significant reductions in disease activity scores (DAS28), inflammatory markers such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR), and subjective pain and physical function assessments with vegan, vegetarian, and plant-forward dietary patterns. …”
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CDK14 regulates the development and repair of lung by Jian-wei Chen, Yu-xiang Wang, Rong-rong Gao, Lan-yue Ma, Jing Zhong, Jia-xin Yang, Zhao-hua Deng, Yu-yan Li, Xiao-ling Li, Ya-hai Shu, Wen-jing Guo, Zi-yuan Zhou, Xiao Yu Tian, Jinjin Ma, Yang Liu, Qi Chen

“…Abstract Cyclin-dependent kinases (CDK) 14 regulates cell cycle, tumor expansion by influencing the downstream targets of the canonical Wnt signaling pathway. However, the function of CDK14 during organ development and regeneration has not been investigated in genetically-modified animals. …”
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Impaired membrane lipids in ischemic stroke: a key player in inflammation and thrombosis by Qian Wang, Dandan Wang, Yan Gao, Jie Jiang, Minghui Li, Shuhui Li, Xiaowen Hu, Jinfeng Wang, Tianqi Wang, Juan Zhang, Lei Feng, Chao Quan, Ping Zhang, Lan Zheng, Chunling Wan

“…Abstract Background Membrane lipids play a crucial role in brain function and cell signalling, and they serve as key biological substrates in inflammatory responses, thrombosis, and energy metabolism. …”
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Analysis of the usefulness and benefits of ultrafiltration in cardiorenal syndrome: A systematic review by Borja Guerrero Cervera, Raquel López‐Vilella, Víctor Donoso Trenado, María Peris‐Fernández, Paula Carmona, Amparo Soldevila, Sergi Tormo, Ramón Devesa, María Jesús Montero Hernández, Luis Martínez Dolz, Julio Hernández Jaras, Pilar Sánchez‐Pérez, Luis Almenar‐Bonet

“…Methods and results Search of the main databases (Pubmed, Embase and Cochrane Central Register of Controlled Trials) identifying comparative studies of UF versus diuretic therapy, from 2000 to the present. …”
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Reduced blood EPAC1 protein levels as a marker of severe coronary artery disease: the role of hypoxic foam cell-transformed smooth muscle cells by Eduardo Garcia, Lene Claudi, Maria Teresa La Chica Lhoëst, Anna Polishchuk, Valerie Samouillan, Aleyda Benitez Amaro, Janet Pinero, Joan Carles Escolà-Gil, Eduard Sabidó, Ruben Leta, David Vilades, Vicenta Llorente Cortes

“…Blood EPAC1 levels were significantly lower in CAD patients compared to controls (p < 0.001). EPAC1 levels were reduced in both men and women with severe CAD (SIS > 4) compared to those with moderate CAD (SIS 1–4). …”
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DNA Vaccine Treatment in Dogs Experimentally Infected with Trypanosoma cruzi by Minerva Arce-Fonseca, Ana C. Carbajal-Hernández, Mónica Lozano-Camacho, Silvia del C. Carrillo-Sánchez, Francisco-Javier Roldán, Alberto Aranda-Fraustro, José Luis Rosales-Encina, Olivia Rodríguez-Morales

“…The two plasmids alone controlled the infection moderately by a reduction in the inflammatory infiltrates in heart tissue. …”
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White matter and cortical gray matter microstructural alterations in migraine: a NODDI and DTI analysis by Zhilei Li, Yanliang Mei, Lei Wang, Tianhua Fan, Cheng Peng, Kaibo Zhang, Shouyi Wu, Tong Chen, Zhenchang Zhang, Binbin Sui, Yonggang Wang, Xueying Yu

“…Current neuroimaging research focuses on changes in brain functional connectivity, functional networks, and macrostructural alterations, which reflect abnormal neuronal function during the disease process. …”
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Association of CALLY index and CLR with COPD risk in middle-aged and older Americans: evidence from NHANES 2017–2020 by Jiaji Zhou, Jiaji Zhou, Wenyi Du, Hanzhou Huang, Hanzhou Huang, Yongqi Chen, Yongqi Chen, Leyan Chen, Leyan Chen, Mingfeng Zheng, Mingfeng Zheng

“…BackgroundChronic obstructive pulmonary disease (COPD) is marked by restrictions on airflow, leading to a gradual and irreversible reduction in lung function. This study assessed the predictive value of hematological inflammatory biomarkers, specifically the C-reactive protein-albumin-lymphocyte (CALLY) index and the C-reactive protein to lymphocyte ratio (CLR), for determining COPD risk in United States adults aged 40 and above.MethodsData were sourced from the National Health and Nutrition Examination Survey (NHANES) covering the period from 2017 to March 2020. …”
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RITUXIMAB TREATMENT FOR INTERSTITIAL LUNG INJURY IN SCLERODERMA SYSTEMATICA by Lidia Petrovna Ananieva, O V Desinova, O A Koneva, M N Starovoitova, N N Yutkina, A V Volkov, O B Ovsyannikova, A P Aleksankin, E N Aleksandrova, A A Novikov, E L Nasonov

“…Further study of dosage regimensfor RTM is required within the framework of controlled trials.…”
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Non3 is an essential Drosophila gene required for proper nucleolus assembly by E. N. Andreyeva, A. A. Ogienko, A. A. Yushkova, J. V. Popova, G. A. Pavlova, E. N. Kozhevnikova, A. V. Ivankin, M. Gatti, A. V. Pindyurin

“…Consistent with its multiple functions, the nucleolus has been implicated in many human diseases, including cancer and degenerative pathologies of the nervous system and heart. …”
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INHALED NITRIC OXIDE: CLINICAL EFFECTS AND INFLUENCE ON THE PROFILE OF INFLAMMATORY MARKERS IN PATIENTS WITH IDIOPATHIC PULMONARY HYPERTENSION by T. V. Martynyuk, S. N. Nakonechnikov, V. P. Masenko, I. E. Chazova

“…The iNO course 40 ppm during 5 hours a day for 21 days was carried out additionally to the standard IPH therapy under the toxicity control by the PrinterNOx (England). Results. Increase in exercise tolerance, improvement of IPH FC (from 3.35±0.52 to 2.71±0.56; p=0.008), reduction in systolic pulmonary artery pressure (SPAP) by Doppler echocardiography (from 96.23±23.65 to 82.36±20.92 mmHg; p&lt;0.05) were found in IPH patients as a result of iNo therapy. …”
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Numerical Simulation of Thermal Fields and Microstructure Evolution in SLM of Fe₃₂Cr₃₃Ni₂₉Al₃Ti₃ Alloy by Xuyun Peng, Xiaojun Tan, Haibing Xiao, Wei Zhang, Liang Guo, Wei Tan, Jian Huang, Chaojun Ding, Yushan Yang, Jieshun Yang, Haitao Chen, Qingmao Zhang

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Some aspects of morphogenesis of diabetic encephalopathy by V. A. Tumanskiy, Yu. N. Avramenko

“…Diabetic encephalopathy in its pure form can be found in 80.7% of patients with diabetes mellitus of the 1st type, its development is caused mainly by ineffective metabolic control of autoregulation of cerebral blood flow [4]. …”
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Impact of Improved Sanitation Standard Operating Procedures on Microbial Populations at Three Tree Fruit Packing Facilities by M. Laura Rolon, Marysabel Mendez Acevedo, Priscilla Sinclair, Dumitru Macarisin, Luke F. LaBorde, Jasna Kovac

“…Cleaning and sanitizing are of vital importance to control Listeria monocytogenes in food processing facilities. …”
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