Role of the protein tyrosine phosphatase Shp2 in homeostasis of the intestinal epithelium. by Hironori Yamashita, Takenori Kotani, Jung-Ha Park, Yoji Murata, Hideki Okazawa, Hiroshi Ohnishi, Yonson Ku, Takashi Matozaki

“…The colitis as well as the reduction in the number of goblet cells apparent in Shp2 CKO mice were normalized by expression of an activated form of K-Ras in IECs. …”
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RNA‐seq analysis of mitochondria‐related genes regulated by AMPK in the human trophoblast cell line BeWo by Bin Wu, Albert Gao, Bin He, Yun Chen, Xiangfeng Kong, Fayuan Wen, Haijun Gao

“…Results Both mitochondrial and glycolytic ATP production in AKD cells were lower than in the control BeWo cells (CT), with a greater reduction of mitochondrial ATP production. …”
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Improving postural stability through proprioceptive training in dogs by Christiane Lutonsky, Nadja Affenzeller, Nadja Affenzeller, Masoud Aghapour, Julia Wegscheider, Christian Peham, Alexander Tichy, Barbara Bockstahler

“…Compared to the control group, the training group showed a statistically significant reduction in CCD% and SS% during uphill standing, and MLD% during downhill standing post-intervention. …”
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Proyecto AVIP (Amigo VIrtual Protésico): estudio de resultados clínico-funcionales y de satisfacción con una aplicación móvil en el manejo perioperatorio y seguimiento de implantes... by J. Diranzo-García, V. Estrems-Díaz, J.F. Garrido-Ferrer, L. Castillo-Ruipérez, V.M. Zarzuela-Sánchez, L. Hernández-Ferrando

“…Results: A total of 68 patients were evaluated, with 31 patients in the AVIP group and 33 in the Control group completing the follow-up. Both groups demonstrated improvement in clinical outcomes based on the WOMAC and mHHS hip tests, a reduction in perceived pain, and an enhancement in quality of life according to the SF-12 test. …”
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Effectiveness of Probiotics, Prebiotics, and Symbiotic Supplementation in Cystic Fibrosis Patients: A Systematic Review and Meta-Analysis of Clinical Trials by Freiser Eceomo Cruz Mosquera, Claudia Lorena Perlaza, Anisbed Naranjo Rojas, Saray Murillo Rios, Alejandra Carrero Gallego, Sara Isabel Fischersworring, Juan Sebastián Rodríguez, Yamil Liscano

“…Sensitivity analyses did not modify the effect of the intervention on pulmonary function or exacerbation frequency, supporting the robustness of the findings. …”
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HISTORICAL DEVELOPMENT OF THE CONSTRUCTION INDUSTRY AND ITS IMPACT ON THE ECONOMIC SECURITY OF THE STATE by Volodymyr Buha, Natalia Blazhivska, Olha Kovalova

“…The genesis of the formation and development of legal regulation of the construction industry in Ukraine was formed under the complex influence of numerous political, social and systemic legal factors and covers separate periods of development: I (IX – early XIV centuries) – the period of existence of Kyivan Rus and feudal fragmentation in the Ukrainian lands, codification of construction legislation and workshop organisation of construction, but almost all construction activities were of a "defensive" nature; II (XIV – XVI centuries) – the period when Ukrainian lands were under the rule of the Grand Duchy of Lithuania and the Kingdom of Poland – the beginning of development planning, taking into account the successful use of territories, ensuring the proper functioning of military and administrative facilities, as well as fire safety; III (XVI – XVIIІ centuries) - the existence of the Cossack-Hetman state – legal regulation and management of construction was limited to purely technical works aimed at strengthening the defence capability of the Zaporozhian Army, therefore it was of exclusively strategic importance; IV (late 18th – early 20th century) – the period when Ukrainian lands were under the rule of the Austrian (Austro-Hungarian) and Russian Empires – the creation of the first specialised agencies authorised to issue permits for certain types of economic activity and to supervise and control construction; V (early twentieth century – 1991) – the period when Ukraine was part of the USSR – a gradual transition to industrial construction methods; consolidation of construction organisations; improvement of design and estimate documentation; growth in labour productivity, quality of work and the formation of the first trade unions at construction enterprises and associations; subsequently, the unification of functions between the main participants in construction – the customer and the contractor – led to a reduction in the contractor's liability; adoption of the first consolidated regulatory act – the Code of Ukraine on Administrative Offences – aimed at regulating administrative and legal relations in the construction sector; Period VI (from 24 August 1991 to the present) – the period of modern Ukraine – consists of two stages 1) in terms of regulatory development, it was marked by the active development of the national legislative framework, and in terms of functionality – by a total reduction in demand for construction products, inflation, which led to a decrease in working capital, imperfect depreciation policy and massive fraud in the housing market; 2) definition of national standards and rules for construction, emergence of new norms in the sectoral legislation and establishment of various sanctions for their violation, formation of the institutional system of the construction industry with subsequent winding up, reorganisation, etc. …”
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Kinetics and dynamics of dissolved organic nitrogen, and nitrogen cycling genes in the soil profile of an irrigated vineyard with surface-applied organic amendments by Mehdi Sharifi, Lori Phillips, Seanna Zintel, Brent Seuradge

“…Microbial N cycling functional potential was determined, and initial DON concentrations, and potentially releasable DON (N0-DON), and the DON release rate constant (k-DON) were assessed via 100-day aerobic incubation. …”
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PRINCIPLES OF RE-ENGINEERING METHODOLOGY FOR TECHNOLOGICAL PROCESS IN PROCESSING OF RAW MATERIAL COMPONENTS WHILE PRODUCING CEMENT AND SILICATE PRODUCTS by I. A. Busel, P. I. Busel

“…Imitation simulations of a grinding mill operation have been developed on the basis of experimental data and probability functions. The possibility of controlling technological process of raw material grinding has been demonstrated in the paper.While implementing the proposed complex of organizational and technical recommendations it is possible to increase grinding productivity up to 30-50 % and significantly reduce и существенно снизить energy consumption for mineral raw material grinding during production of cement and silicate products. …”
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Analysis of biofilm assembly by large area automated AFM by Ruben Millan-Solsona, Spenser R. Brown, Lance Zhang, Sita Sirisha Madugula, HuanHuan Zhao, Blythe Dumerer, Amber N. Bible, Nickolay V. Lavrik, Rama K. Vasudevan, Arpan Biswas, Jennifer L. Morrell-Falvey, Scott Retterer, Martí Checa, Liam Collins

“…Understanding their assembly, structure, genetic regulation, interspecies interactions, and environmental responses is key to developing effective control and mitigation strategies. While atomic force microscopy (AFM) offers critically important high-resolution insights on structural and functional properties at the cellular and even sub-cellular level, its limited scan range and labor-intensive nature restricts the ability to link these smaller scale features to the functional macroscale organization of the films. …”
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Inactivated Rothia nasimurium promotes a persistent antiviral immune status in porcine alveolar macrophages by Aida Tort-Miró, Aida Tort-Miró, Aida Tort-Miró, Uxía Alonso, Beatriz Martín-Mur, Beatriz Martín-Mur, Jordana Muñoz-Basagoiti, Jordana Muñoz-Basagoiti, Jordana Muñoz-Basagoiti, Yan Zeng, David Marín-Moraleda, David Marín-Moraleda, David Marín-Moraleda, Enrique Ezcurra, Enrique Ezcurra, Enrique Ezcurra, Sergio Montaner-Tarbes, Sergio Montaner-Tarbes, Sergio Montaner-Tarbes, María J. Navas, María J. Navas, María J. Navas, Marta Muñoz, Marta Muñoz, Marta Muñoz, Paula Monleón, Paula Monleón, Paula Monleón, Judith González-Oliver, Judith González-Oliver, Judith González-Oliver, Esmeralda Cano, Esmeralda Cano, Esmeralda Cano, Carles Vilalta, Carles Vilalta, Carles Vilalta, Marc Caballé, Lourdes Criado, Karl Kochanowski, Karl Kochanowski, Karl Kochanowski, Francesc Accensi, Francesc Accensi, Virginia Aragón, Virginia Aragón, Virginia Aragón, Florencia Correa-Fiz, Florencia Correa-Fiz, Florencia Correa-Fiz, Anna Esteve-Codina, Anna Esteve-Codina, Fernando Rodríguez, Fernando Rodríguez, Fernando Rodríguez, Jordi Argilaguet, Jordi Argilaguet, Jordi Argilaguet

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“Physicochemical characterization and microbial quality evaluation of Gracilaria tenuistipitata added crackers’’ by Ananya Raiyan, Md. Mohasin Hossain, Md. Ashrafuzzaman Zahid, Nazia Nawshad Lina, Suvasish Das Shuvo, Rashida Parvin

“…Three formulations were used: control (0 % seaweed powder), T1 (1 % seaweed powder), and T2 (2 % seaweed powder). …”
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Combined effects of Yupingfeng and metformin on blood glucose levels and intestinal tissue in high-fat diet-induced type 2 diabetic rats by Hui Liu, Hui Liu, Yuan Guan, Like Xu, Ji Hu, Ji Hu

“…Beginning in the third week, the combined administration of Yupingfeng and metformin significantly reduced fasting insulin levels, blood glucose concentrations, and insulin resistance compared to the control group, with further marked reductions observed by the seventh week (p< 0.01). …”
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Combined effects of extreme climatic events and elevation on nutritional quality and herbivory of Alpine plants. by Annette Leingärtner, Bernhard Hoiss, Jochen Krauss, Ingolf Steffan-Dewenter

“…However, the response of plant-herbivore interactions to extreme events and climatic gradients has been rarely studied, although climatic extremes will increase in frequency and intensity in the future and insect herbivores represent a highly diverse and functionally important group. We set up a replicated climate change experiment along elevational gradients in the German Alps to study the responses of three plant guilds and their herbivory by insects to extreme events (extreme drought, advanced and delayed snowmelt) versus control plots under different climatic conditions on 15 grassland sites. …”
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Reversibility of chronic heart failure symptoms in chronic kidney disease patients by V. V. Belov, O. E. Ilyicheva

“…To investigate reversibility of clinical symptoms, plus structural and functional myocardial changes in chronic heart failure (CHF) and terminal chronic kidney disease (CKD) patients, before dialysis and in the first year of programmed hemodialysis. …”
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Resistance training as a modulator of inflammation and cognition by Jacqueline Goodrich, Jamie L. Tartar, Jonathan Banks, Francesca Leon, Jose Antonio

“…These findings suggest that resistance training may improve cognitive function and body composition, despite no measurable reductions the inflammatory biomarkers IL-6 and CRP.Conclusions The results of this study support the beneficial effects of resistance training on cognition. …”
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Dapagliflozin combined with methylcobalamin in the treatment of type 2 diabetes mellitus with peripheral neuropathy: a systematic review and meta-analysis by Xiao-Long Deng, Ren Wu, Xuan-Xia Lin, Jia-Jian Liang, Han-Wei Huang

“…There was no significant increase in adverse events (OR: 0.37; 95% CI: 0.07–2.03; P=0.25).ConclusionDapagliflozin combined with methylcobalamin appears to be an effective and safe therapeutic strategy for managing DPN in T2DM patients, improving both nerve function and glycemic control.…”
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Efficacy of duloxetine in treating temporomandibular joint disorder: a systematic review with bayesian meta-analysis by Sasidharan Sivakumar, Ashok K. Sundramoorthy, Sankar Narayanan, Julia Thenmozhi J, Gowardhan Sivakumar

“…Bayesian analysis strongly supported pain reduction (BF10 = 44.197) but was inconclusive for functional improvement (BF10 = 0.783). …”
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Altered Theta Oscillations and Aberrant Cortical Excitatory Activity in the 5XFAD Model of Alzheimer’s Disease by Magdalena Elisabeth Siwek, Ralf Müller, Christina Henseler, Astrid Trog, Andreas Lundt, Carola Wormuth, Karl Broich, Dan Ehninger, Marco Weiergräber, Anna Papazoglou

“…We also observed a reduction in mean theta frequency in 5XFAD mice compared to controls that was again most prominent during nonmotor activity. …”
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Long Non-Coding RNA THRIL Promotes Influenza Virus Replication by Inhibiting the Antiviral Innate Immune Response by Mengying Chen, Jingyun Hu, Xinni Zhou, Ming Gao, Ning Li, Guihong Yang, Xiaojuan Chi, Song Wang

“…Additionally, IAV infection led to notable reductions in the expression levels of type I and type III interferons in cell lines overexpressing THRIL compared to control groups; conversely, cell lines with THRIL knockdown exhibited significantly higher interferon levels than control groups. …”
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5′-Adenosine Monophosphate-Induced Hypothermia Attenuates Brain Ischemia/Reperfusion Injury in a Rat Model by Inhibiting the Inflammatory Response by Yi-Feng Miao, Hui Wu, Shao-Feng Yang, Jiong Dai, Yong-Ming Qiu, Zhen-Yi Tao, Xiao-Hua Zhang

“…The overall infarct volume was significantly smaller in AIH-treated rats, and neurological function was improved. By contrast, rats with ischemic brain injury that were administered 5′-AMP without inducing hypothermia had ischemia/reperfusion injuries similar to those in euthermic controls. …”
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