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2561
Enhancing blood glucose regulation and antioxidant activity in high-protein, high-fiber composite cookies: A study of whole-wheat, sweet potato, peanut, and rice bran incorporation
Published 2025-03-01“…The in vitro and in vivo antioxidants, blood sugar reducing and liver function indices of the streptozotocin induced rats were examined. …”
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2562
Retinoic acid regulates the proliferation, differentiation, and cell death of limb skeletal progenitors, contributing to establish the size and identity of the digits
Published 2025-07-01“…RA gain- and loss-of-function experiments via pharmacological approaches confirmed a close correlation between interdigital RA and digit size. …”
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2563
Mechanism of Cationic Peptide‐Induced Assembly of Gold Nanoparticles: Modulation of Electrostatic Repulsion
Published 2025-06-01“…ABSTRACT The aggregation of plasmonic nanoparticles can lead to new and controllable properties useful for numerous applications. …”
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2564
Sucla2 Knock‐Out in Skeletal Muscle Yields Mouse Model of Mitochondrial Myopathy With Muscle Type–Specific Phenotypes
Published 2024-12-01“…Results Molecular validation confirmed 68% reduction of Sucla2 transcript within the mutant skeletal muscle (p < 0.001) and 95% functionally reduced SUCLA2 protein (p < 0.0001). …”
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2565
Trimetazidine MR effects on heart remodeling in stable coronary heart disease patients
Published 2007-02-01“…In stable good clinical status, no obvious clinical dynamics, and unchanged ejection fraction, structural and functional cardiac parameters improved substantially, with reduction (р<0,00001) in MSs (145,68±11,35 and 124,51±7,89); MSd (160,72±16,78 and 156,24±12,11), end-diastolic pressure (14,81±3,16 and 11,9±1,91 mm Hg), end-diastolic LV wall strain (1967,33±337,27 and 1519,99±224,74 dyne/cm2), as well as with increase in RI (93,72±8,48 and 100,87±9,74). …”
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2566
Indapamide retard in complex therapy of patients with chronic heart failure and arterial hypertension
Published 2010-04-01“…To investigate indapamide retard effects on clinico-laboratory parameters and clinical course in patients with Functional Class (FC) II-IV chronic heart failure (CHF) and arterial hypertension (AH). …”
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2567
PROSPECTS OF APPLICATION OF THE CONCEPTOF QUICK RESPONSE MANUFACTURING AT THE RUSSIAN INDUSTRIAL ENTERPRISES
Published 2016-11-01“…Today domestic producers are compelled to function in new conditions, competing with a great number of players of the global market, as a result the emphasis on timely implementation of orders and a tendency of reduction of time of production will allow to reach competitive advantages. …”
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2568
DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans.
Published 2014-02-01“…The DAF-16/FoxO transcription factor controls growth, metabolism and aging in Caenorhabditis elegans. …”
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2569
Optimizing skin cancer screening with convolutional neural networks in smart healthcare systems.
Published 2025-01-01“…In this researche new activation function namely NGNDG-AF was offered specifically to enhance the capabilities of network fitting and generalization ability, convergence rate and reduction in mathematical computational cost. …”
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2570
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INT‐787, a Novel Farnesoid X Receptor Agonist, in Healthy Volunteers: A Phase 1 Trial
Published 2025-05-01“…In preclinical/clinical studies, semisynthetic bile acid‐derived FXR agonists markedly improved hepatic function in various conditions. INT‐787, a novel hydrophilic semisynthetic bile acid FXR agonist, has demonstrated a reduction in inflammatory and fibrotic markers and regulation of bile acid/lipid metabolism. …”
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2571
Morin Ameliorates Myocardial Injury in Diabetic Rats via Modulation of Autophagy, Apoptosis, Inflammation, and Oxidative Stress
Published 2024-12-01“…After treatment with a dose of 25, 50, and 100 mg/kg/day orally for the next 60 days, autophagic (p62, LC3, and BECN1), apoptotic (BCL2, CASP-3, and CASP9), inflammatory (IL-1β, IL-6, TNF-α), and oxidative stress (CAT, SOD, and MDA) markers in protein and gene levels as well as cardiac function tests were measured.Results: The findings revealed that long-term morin treatment improved weight gain, lipid and glycemic profile, hypertension, and cardiac hypertrophy and fibrosis in diabetic rats compared to controls (p-value< 0.001). …”
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2572
Sugammadex vs neostigmine in post-anesthesia recovery: A systematic review and meta-analysis
Published 2025-08-01“…In conclusion, sugammadex provides a faster reversal of neuromuscular blockade compared to neostigmine and is associated with a reduction in postoperative complications. However, this expedited reversal does not result in measurable improvements in overall recovery quality, nor do either sugammadex or neostigmine significantly affect postoperative cognitive function. …”
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2573
Atrazine sensitivity varies among soybean cultivars
Published 2025-03-01“…Under 9.0 g a.i. ha−1 atrazine, SH 5515 LL exhibited visual injury and aboveground fresh biomass reduction but was unaffected in net photosynthesis rate (A) and effective quantum yield of photosystem II (ϕPSII) compared to controls. …”
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2574
Superoxide dismutase and antioxidant status of hens' granulosa cells exposed to lead and molybdenum
“…Higher doses of both metals caused significant reduction of SOD activity. TAS of cells was decreased in experimental groups.…”
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2575
Tyrosinase-Catalyzed Soy Protein and Tannic Acid Interaction: Effects on Structural and Rheological Properties of Complexes
Published 2025-03-01“…Tyrosinase-induced polymerization significantly impacted the conformational structure of SPI, evidenced by a notable decrease in intrinsic fluorescence, a pronounced red shift, and a remarkable reduction in surface hydrophobicity. FTIR analysis further revealed that, compared to control SPI, the amide I, II, and III bands of SPI incubated with TA and tyrosinase exhibited varying degrees of red-shift or blue-shift. …”
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2576
Effects of Kefir Powder Fortification on Yogurt Qual
Published 2018-06-01“…The aim of this research was to improve functional properties and sensory of plain set type yogurt since yogurt bacteria have low probiotic properties. …”
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2577
PRECISION, STABILITY ANALYSIS OF THE CRANKSHAFT GRINDING TECHNOLOGICAL PROCESS
Published 2019-01-01“…The structural and functional representation of the object is also used for research, and the model for the analysis of the grinding process serves as the basis for the decomposition.Results. …”
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2578
Mechanistic insights into effects of the cardiac myosin activator omecamtiv mecarbil from mechanokinetic modelling
Published 2025-04-01“…Repeated tests lead to at a set of parameter values that allow faithful reproduction of range of functional variables of cardiac myocytes. We then apply the model to studies of OM.Results and discussionThe results suggest that major effects of OM such as large reduction of the maximum velocity with more limited effects on maximum isometric force and slowed actin-activated ATPase can be accounted for by two key molecular effects. …”
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2579
Re-Creating the Ethnic Cultural Identity among the Arab People of Khuzestan
Published 2022-05-01“…In general, the findings of the research about some of the most important variables affecting the re-creation of ethnic identity among the arab people of khuzestan province include: the functional weakness of civil institutions, the reduction of the cultural control of the central government, cultural tourism, greater acceptance of cultural pluralism, programs of local television channels (arabic) of iran broadcasting organization, growth of cultural capital, social mobility, feeling of relative deprivation and indifference of the political system to ethnic cultural identities in cultural policies. …”
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2580
Hydrodynamic Performance of A-Jacks Concrete Armor Units in Riverbeds around Downstream in Flip Buckets
Published 2021-01-01“…Erosion of river bed materials downstream of dams could affect the performance of dams or power plants by altering the tailwater depth, rendering proper designs of controlling structures or erosion reduction methods highly indispensable in this regard. …”
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