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2521
Impact of pancreatic cell-engineered constructs on the islet apparatus in recipient rats with type I diabetes mellitus
Published 2025-07-01“…In the pancreatic islets of the control group, insulin- immunopositive beta cells were either absent or detected as isolated cells, with alpha cells predominating. …”
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2522
Novel Applications of Lactic Acid and Acetic Acid Bacteria Preparations in Shaping the Technological and Microbiological Quality of Ready-to-Cook Minced Pork
Published 2025-05-01“…Lipid oxidation, measured by TBARS, was significantly reduced in treated samples (0.34–0.37 mg MDA/kg) compared to the control (0.43 mg MDA/kg) by day 9. Microbial counts were markedly lower: total viable counts in treated samples did not exceed 3.2 log CFU/g, whereas the count in the control reached 4.6 log CFU/g. …”
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2523
Improved Inconel 718 superalloy repaired performance on 304 stainless steel shafts via recrystallization and Laves phase suppression in hybrid additive-subtractive manufacturing
Published 2025-07-01“…The HASM process orchestrates multistage thermo-mechanical control through OAFW-LDED/milling cycles, achieving controlled material deposition and unique microstructural evolution via mitigated thermal accumulation, enhanced solidification rates, and localized remelting-recrystallization. …”
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2524
How does chronic unpredictable mild stress affect the number of mature oocytes? An experimental study
Published 2025-05-01“…Oxidative stress disrupts normal cellular functions, leading to reduced survival of antral follicles through increased glucocorticoids. …”
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2525
Exploring the impact of Plantago lanceolata mucilage edible coating enhanced with Lacticaseibacillus rhamnosus CWKu-12 postbiotics on the shelf life of lamb meat slices
Published 2025-06-01“…However, the coated samples had significantly lower microbial counts than those in the control (p < 0.05). When compared to the uncoated control, the lamb slices treated with the PLM+2 %CFS coating demonstrated a substantial reduction in, pH value (6.05 vs. 5.68), thiobarbituric acid value (0.68 vs. 0.20 mg MDA/kg), and peroxide value (5.66 vs. 2.51 meq oxygen/kg), and. …”
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2526
Dynamics of personal attitudes of inpatients with schizophrenia as a result of treatment with psychosocial interventions
Published 2025-06-01“…It was proven that patients of the main subgroup (who took part in treatment with the use of a specialized psychoeducational program) changed their ideas about their disease, its severity, main symptoms and ways of their control, increased confidence in the ability to control symptoms and the level of compliance with therapy. …”
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2527
Effects of Phaseolus vulgaris Extract on Lipolytic Activity and Differentiation of 3T3-L1 Preadipocytes into Mature Adipocytes: A Strategy to Prevent Obesity
Published 2019-01-01“…These results suggest that bean is a good candidate for the development of functional ingredients that can help reduce the high rates of death from cardiovascular diseases associated with obesity.…”
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2528
Integration of Daylight in Building Design as a Way to Improve the Energy Efficiency of Buildings
Published 2025-08-01“…The OECD reports indicate the use of Building Information Modelling (BIM) as one of the effective strategies for decarbonization of buildings, since a 3D digital representation of both physical and functional characteristics of a building can help to design a more efficient infrastructure. …”
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2529
Hemodynamic indicators of doppler test within arteria profunda linguae in patients with combined pathology of mucous membrane of oral cavity and rheumatoid arthritis
Published 2017-08-01“…Elastic properties of the vascular wall reduction indicate circulation intensity decrease in arteria profunda linguae system, which is a sighn of chronic inflammatory process. …”
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2530
Ultrasound-triggered drug release and cytotoxicity of microbubbles with diverse drug attributes
Published 2025-01-01“…Ultrasound (US)-triggered cavitation of drug-loaded microbubbles (MBs) represents a promising approach for targeted drug delivery, with substantial benefits attainable through precise control over drug release dosage and form. This study investigates Camptothecin-loaded MBs (CPT-MBs) and Doxorubicin-loaded MBs (DOX-MBs), focusing on how properties such as hydrophilicity, hydrophobicity, and charged functional groups affect their interaction with the lipid surfaces of MBs, thereby influencing the fundamental characteristics and acoustic properties of the drug-loaded MBs. …”
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2531
Numerical case study on thermal efficiency and predictive thermal management in Type-4 wind turbines
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2532
Stormwater Management: An Integrated Approach to Support Healthy, Livable, and Ecological Cities
Published 2024-07-01“…Research into stormwater management addresses its functional areas of drainage, flood control, flood plain management, water quality control, urban ecology, recreation, and city beautification. …”
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2533
Clinical and diagnostic manifestations in women of reproductive age having both hyperthyroidism and hyperandrogenism
Published 2020-01-01“…Of these, 17 patients (27.0 %) were diagnosed with hyperthyroidism and HA. The control group included 20 practically healthy women of the similar age (20–44 years old) with no signs of HA or other hormonal disorders. …”
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2534
Nutritional, Physicochemical, and Organoleptic Properties of Camel Meat Burger Incorporating Unpollinated Barhi Date Fruit Pulp
Published 2022-01-01“…Interestingly, adding UBDF as fiber source at 7.5-15% presented overall acceptability of more than 90% compared to the control sample of 81.7%. In the same context, adding UBDF as a fat replacer at 100% replacing the level of added fats scored overall acceptability of more than 93.60% compared to the control sample of 67.4%. …”
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2535
Spotlight on the Mechanism of Action of Semaglutide
Published 2024-12-01“…Integrating the latest clinical trials, semaglutide in patients with or without diabetes presents significant therapeutic efficacy in ameliorating cardiometabolic risk factors and physical functioning, independent of body weight reduction. Semaglutide may modulate adipose tissue browning, which enhances human metabolism and exhibits possible benefits in skeletal muscle degeneration, accelerated by obesity and ageing. …”
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2536
Synthesis of <i>N</i>,<i>N</i>-Dimethylaminopropyl Derivative of A Blood Sugar Antigen
Published 2025-03-01“…This side reaction might be ascribed to the in situ formation of formaldehyde and successive imine formation and reduction. The obtained compound can be used as a monomeric control compound in biochemical and structural biology studies involving ABO blood sugar antigens.…”
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2537
HLA Class Ia and Ib Polyreactive Anti-HLA-E IgG2a Monoclonal Antibodies (TFL-006 and TFL-007) Suppress Anti-HLA IgG Production by CD19+ B Cells and Proliferation of CD4+ T Cells Wh...
Published 2017-01-01“…The anti-HLA-E mAb expanded CD4+, CD25+, and Foxp3+ Tregs, which are known to suppress T and B cells involved in antibody production. These defined functions of the anti-HLA-E IgG2a mAbs at a level superior to IVIg encourage developing their humanized version to lower antibodies in allograft recipients, to promote graft survival, and to control autoimmune diseases.…”
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2538
Liver‐directed gene therapy for ornithine aminotransferase deficiency
Published 2023-01-01“…In two mouse models of OAT deficiency that recapitulates biochemical and retinal changes of GACR, we investigated the efficacy of an intravenously injected serotype 8 adeno‐associated (AAV8) vector expressing OAT under the control of a hepatocyte‐specific promoter. Following injections, OAT‐deficient mice showed reductions of ornithine concentrations in blood and eye cups compared with control mice injected with a vector expressing green fluorescent protein. …”
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2539
Assessing the impact of moxibustion on colonic mucosal integrity and gut microbiota in a rat model of cerebral ischemic stroke: insights from the “brain-gut axis” theory
Published 2025-02-01“…Neurological function was assessed using the Longa score, and brain infarct size was assessed through 2,3,5-triphenyl tetrazolium chloride staining. …”
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2540
Haploinsufficiency of ABL1 is associated with dominant isolated omphalocele
Published 2025-08-01“…Quantification of the ABL1 mRNA abundance showed its significant reduction in an affected allele carrier compared to a healthy control. …”
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