Changes in the density of astrocytes in the brain of rats caused by a single prolonged stress by Ivaz Sava, Stojković Tihomir, Petronijević Nataša

“…The density of GFAP+ astrocytes was statistically significantly lower in mPFC region of rat brains treated by SPS compared to the control group (p < 0.01). Conclusion: The results indicate that SPS leads to a significant reduction in the density of astrocytes in the hippocampus and mPFC, which suggests that changes in astrocytes may play a role in the development of morphological and functional disorders triggered by PTSD. …”
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DIAGNOSTIC VALUE OF MARKERS OF ENDOTHELIUM VESSELS INJURY IN DIABETES TYPE 2 WITH ARTERIAL HYPERTENSION by N. E. Tadtaeva, O. O. Basieva

“…The purpose of the investigation is to study the breach of functional endothelial activity of the patients with type 2 diabetes (DM2) with arterial hypertension. …”
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Effect of the Foliar Application of Copper Nanoparticles on the Growth and Yield of Persian Leek (Allium ampeloprasum subsp. Persicum) under Salinity Stress by F. Shakarami, S. Mousavi-Fard, A. Rezaei Nejad, F. Beiranvand

“…The first factor involved foliar spraying of copper nanoparticles at control levels (zero), 150, and 300 mg.l-1, while the second factor comprised salinity stress at control levels (zero), 50, 100, and 150 mM sodium chloride. …”
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Comparative efficacy of preventive vs. therapeutic resveratrol in modulating gut microbiota and alleviating inflammation in DSS-induced colitis by Senmei Qin, Zongjing Yang, Jinqing Lei, Qingli Xie, Linsui Jiang, Yuanyuan Fan, Yonggu Luo, Kecong Wei, Wei Luo, Bing Yu

“…Mechanistically, PRE normalized barrier function via transcriptional (ZO-1: 56.7% of CON; Occludin: 14-fold induction vs. …”
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Whole exome sequencing identifies FANCM as a susceptibility gene for estrogen-receptor-negative breast cancer in Hispanic/Latina women by Jovia L. Nierenberg, Aaron W. Adamson, Donglei Hu, Scott Huntsman, Carmina Patrick, Min Li, Linda Steele, Shu Tao, Yuan Chun Ding, Barry Tong, Yiwey Shieh, Laura Fejerman, Stephen B. Gruber, Christopher A. Haiman, Esther M. John, Lawrence H. Kushi, Gabriela Torres-Mejía, Charité Ricker, Jeffrey N. Weitzel, Elad Ziv, Susan L. Neuhausen

“…We conducted a pooled case-control analysis in self-identified Hispanic/Latina women (4178 cases and 4344 controls), using whole exome sequencing and a targeted panel. …”
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The impact of site-specific DNA methylation in KCNJ11 promoter on type 2 diabetes by Mengmeng Zhu, Qiaoliang Huang, Heng Li, Yujie Zhao, Heming Guo, Tao Wang, Xiaodan Liu, Yun Huang, Ji Hu, Chen Fang, Jian Huang

“…Methods: Thirty patients newly diagnosed with T2DM and 30 healthy controls were selected to determine the CpG methylation levels in the promoter region of the KCNJ11 gene using the bisulfite assay. …”
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Cardioprotective effects of liposomal resveratrol in diabetic rats: unveiling antioxidant and anti-inflammatory benefits by Ahmed Z. Alanazi, Mohammed Alqinyah, Abdullah S. Alhamed, Hanan Mohammed, Mohammad Raish, Khaldoon Aljerian, Jawza F. Alsabhan, Khalid Alhazzani

“…Adult male Wistar rats were categorized into five groups: control, diabetic, resveratrol-treated (40 mg/kg), liposomal resveratrol (LR)-treated (20 mg/kg) and liposomal resveratrol (LR)-treated (40 mg/kg) for a five-week study period. …”
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Synergistic effects of berberine and curcumin-loaded chitosan nanoparticles in Nile tilapia: mitigating high-carbohydrate diet-induced metabolic dysfunction, hepatic injury, and im... by Ekramy Elmorsy, Ali A. El-Raghi, Ibrahim T. El-Ratel, Mahmoud A. Hassan, Helal F. Hetta, Mohamed E. Mohamed, Kasim S. Abass, Samah F. Ibrahim, Heba Allah M. Elbaghdady

“…The B-CR-CHNPs treatment significantly enhanced growth, feed utilisation, protein efficiency, digestive enzyme activities, blood protein levels, liver function, and lipid metabolism compared to the HCD group (p < 0.05). …”
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The effects of different exercise training protocols on mitochondrial dynamics in skeletal and cardiac muscles of Wistar rats by Amir Hossein Haghighi, Mohammad Reza Bandali, Roya Askari, Hadi Shahrabadi, Rosario Barone, Roberto Bei, Pasquale Farsetti, Marco Alfonso Perrone

“…Abstract Background Mitochondrial fission and fusion both contribute to maintaining mitochondrial function and optimizing bioenergetic capacity. Objective The aim of this study was to compare the effect of aerobic and resistance training on mitochondrial fission and fusion markers in skeletal and cardiac muscles of Wistar rats. …”
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Temporary dietary fiber depletion prompts rapid and lasting gut microbiota restructuring in mice by Colombe Rous, Julie Cadiou, Hiba Yazbek, Elena Monzel, Mahesh S. Desai, Joel Doré, Maarten van de Guchte, Stanislas Mondot

“…Fiber deprivation was accompanied by a reduction of microbiota diversity and an increase in mucolytic and sulfate-reducing bacteria. …”
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SGLT2 inhibitors in preventing progression of chronic kidney disease in patients with type 2 diabetes: a literature review by Michał Szczepański, Marcin Kuliga, Mateusz Bajak, Julia Słowik, Julia Inglot, Jadwiga Inglot, Dominik Maciej Feret, Daniel Zapasek, Maciej Mamczur, Damian Sowa

“…Clinical studies have demonstrated significant therapeutic benefits, including a reduction in albuminuria and improvement in renal function. …”
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Effects of sacubitril/valsartan on hypertensive heart disease: the REVERSE-LVH randomized phase 2 trial by Vivian Lee, Mayank Dalakoti, Qishi Zheng, Desiree-Faye Toh, Redha Boubertakh, Jennifer A. Bryant, Tar-Choon Aw, Chi-Hang Lee, A. Mark Richards, Javed Butler, Javier Díez, Roger Foo, Stuart A. Cook, Carolyn SP Lam, Thu-Thao Le, Calvin WL Chin

“…Other markers of cardiac volumes, function and mechanics were similar between the two treatment arms. …”
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A Conceptual Investigation of a Large Radio Telescope Support Point Number Effect on Its Pointing Accuracy by Song Xue, Kaitong Ma, Congsi Wang, Peiyuan Lian, Yan Wang, Yuefei Yan, Qian Xu, Yuanpeng Zheng, Na Wang

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A Study on the Effects of Gluteal Muscle Activation on the Electromyography of Lower Limb Muscles in Young Male Patients With Patellofemoral Pain Syndrome by Wu Yue, Ren Shuang, Huang Hongshi, Ao Yingfang, Gou Bo

“…ABSTRACT Objective Patellofemoral pain syndrome (PFPS) is a common knee issue, and hip joint function significantly affects knee health. Gluteus activation exercises are a promising treatment for PFPS. …”
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Comparison of Clinical Outcomes Between Fluoroscopic and Computer Tomographic Guidance in Concurrent Use of Radiofrequency Ablation and Vertebral Augmentation in Spinal Metastases:... by Qing Zhao Ruan, Syena Sarrafpour, Jamal Hasoon, R. Jason Yong, Christopher L. Robinson, Matthew Chung

“…This combination therapy of RFA with VA, which could be performed under CT or fluoroscopy, has in recent years been recognized as highly successful for pain control and functional restoration of metastatic spine lesions. …”
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Coilin Affects the Prognosis of Hepatocellular Carcinoma Through Cell Cycle and Apoptosis by Lu L, Zhou X, Zheng J, Li D

“…Knockdown of COIL expression inhibited the proliferation, migration, and invasion of Hep3B, HepG2, and Huh7. Compared to the control group, COIL knockdown cells showed a marked reduction in CDC25C and CCNB1 protein levels, suggesting that COIL knockdown leads to G2/M phase cell cycle arrest. …”
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Reduced lung metastasis in endothelial cell-specific transforming growth factor β type II receptor-deficient mice with decreased CD44 expression by Kako Hanada, Yuki Saito, Takahiro Takagi, Mitsuki Go, Yota Nakano, Toshihiko Inagawa, Hideyo Hirai, Marcus Fruttiger, Susumu Itoh, Fumiko Itoh

“…These findings highlight TGF-β′s role in promoting metastasis by modulating EC function.…”
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Introducing a Novel Personalized Microbiome-Based Treatment for Inflammatory Bowel Disease: Results from NostraBiome’s Internal Validation Study by Adrian Goldiș, Radu Dragomir, Marina Adriana Mercioni, Christian Goldiș, Diana Sirca, Ileana Enatescu, Oana Belei

“…<b>Results</b>: PMM led to significant clinical improvements, including a 58% reduction in stool frequency (<i>p</i> < 0.001) and improved stool consistency. …”
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Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells. by Ashutosh Arun, Kayla J Rayford, Ayorinde Cooley, Tanu Rana, Girish Rachakonda, Fernando Villalta, Siddharth Pratap, Maria F Lima, Nader Sheibani, Pius N Nde

“…To elucidate the significance of TSP1 function in YAP/β-catenin colocalization and how they impact parasite infectivity during the early phase of infection, we challenged mouse heart endothelial cells (MHEC) from wild type (WT) and TSP1 knockout mice with T. cruzi and evaluated Wnt signaling, YAP/β-catenin crosstalk, and how they affect parasite infection. …”
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Effectiveness and Safety of Nebulized Magnesium as Last Line Treatment in Adults with Acute Asthma Attack: A Systematic Review and Meta-Analysis by Danny Darmawan, Iris Rengganis, Cleopas Martin Rumende, Hamzah Shatri, Soekamto Koesnoe, Yogi Umbarawan, Rudi Putranto, Sally Aman Nasution

“…Conclusion: Inhaled magnesium improves the outcome of asthmatic patients, especially in lung function, clinical severity, and respiratory rate. …”
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