Caspar specifies primordial germ cell count and identity in Drosophila melanogaster by Subhradip Das, Sushmitha Hegde, Neel Wagh, Jyothish Sudhakaran, Adheena Elsa Roy, Girish Deshpande, Girish S Ratnaparkhi

“…Embryonic development in metazoans is controlled by maternal factors deposited in the egg during oogenesis. …”
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Molecular mechanisms and cancer-promoting roles of sodium arsenite in regulating FNDC3B expression in A549 cells by Jinyun JIANG, He MA, Na LIU, Ruihuan ZHAO, Chenglan JIANG, Yuefeng HE

“…MMA and DMA exhibited no impact on FNDC3B protein expression. (2) Following the specific knockdown of FNDC3B expression in A549 cells, the CCK-8 assay demonstrated a significant reduction in cell viability in the silenced FNDC3B group (si-FNDC3B) compared to the control group. …”
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Fatigue in Patients with Parkinson’s Disease by Kazuo Abe, Mayako Takanashi, Takehiko Yanagihara

“…Results: Patients with PD had normal cognitive function as judged by the MMSE, but showed significantly high scores with the fatigue and depression scales in comparison to controls (p). …”
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Physical Activity and Sedentary Behavior in Preterm-Born 7-Year Old Children. by John Lowe, W John Watkins, Sarah J Kotecha, Sailesh Kotecha

“…Boys born at ≤32 weeks' gestation had modest but statistically significant reductions in MVPA when compared to term controls. This equated to a reduction of 9 minutes per day. …”
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Glymphatic system impairment along the perivascular space in adults with moyamoya disease: A systematic review and meta-analysis by Sadegh Ghaderi, Sana Mohammadi, Farzad Fatehi

“…Results: Four studies (172 patients with moyamoya disease and 104 healthy controls) were included. The pooled meta-analysis revealed a statistically significant reduction in the DTI-ALPS index in patients with moyamoya disease compared to healthy controls (Cohen's d = −0.38, 95 % CI: −0.68, −0.09; p = 0.01), indicating impaired glymphatic function. …”
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Gasdermin D deletion prevents liver injury and exacerbates extrahepatic damage in a murine model of alcohol-induced ACLF by Yuan Zhuang, Gyongyi Szabo, Martí Ortega-Ribera, Veronika Brezani, Radhika S Joshi, Zsuzsanna Zsengeller, Prashanth Thevkar Nagesh, Aditi Datta

“…Nine hours after the alcohol binge, blood, liver, kidney and cerebellum specimens were collected for analysis.Results Active GSDM-D was significantly increased in humans and mice ACLF livers compared with both healthy controls and cirrhotic livers. GSDM-D-deficient mice with ACLF showed decreased inflammation, neutrophil infiltration and fibrosis in the liver, together with a reduction in pyroptotic, apoptotic and necroptotic death, compared with WT ACLF mice. …”
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Effectiveness of Teriparatide on Fracture Healing: A Systematic Review and Meta-Analysis. by Zhongju Shi, Hengxing Zhou, Bin Pan, Lu Lu, Jun Liu, Yi Kang, Xue Yao, Shiqing Feng

“…There was a significant effectiveness with regards to function improvement in patients following fracture, however, there was no significant effectiveness with regards to time of radiographic fracture healing, fracture healing rate and reduction in pain.…”
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EFFICACY OF PHYSICAL EXERCISES IN PATIENTS WITH OSTEOPOROTIC VERTEBRAL FRACTURES by Lyudmila P Evstigneeva, E V Kozhemyakina, E V Negodaeva, G A Gusel'nikova, A A Belkin, D N Vikulova, N V Belkin, O M Lesnyak

“…After 12 months, the study group showed a statistically significant reduction of time required to execute the «Stand up and walk» test from 12.1 ± 3.8 to 10.8 ± 2.5 s (p = 0.028), while no changes were observed in the control group (11.1 ± 3.4 and 11.1 ± 2.8 s respectively). …”
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Caspase-11 and NLRP3 exacerbate systemic Klebsiella infection through reducing mitochondrial ROS production by Yuqi Zhou, Zhuodong Chai, Ankit Pandeya, Ling Yang, Yan Zhang, Guoying Zhang, Congqing Wu, Zhenyu Li, Yinan Wei

“…Deficiency of caspase-11 or NLRP3 led to prolonged survival, a reduction in pulmonary bacterial load, increased blood oxygen levels, and decreased IL-6 levels in the lungs compared to WT controls. …”
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Efficacy of suspension exercise training in spinal cord injury: a systematic review and meta-analysis by Yuntao Li, Minmin Wu, Jiguang Pan, Luwen Zhu

“…Significant improvements were observed in all of the aforementioned outcome indicators, suggesting that SET is likely to be effective in restoring function in patients with SCI. Conclusion This study has demonstrated that SET is likely to improve motor and balance functions, as well as activities of daily living, in patients, while also contributing to a reduction in muscle tone. …”
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Hygiene and prevention of the addictions in adolescents: existential-humanistic model by P. N. Moskvitin

“…Science-based organizational and functional mechanism of prevention had based on a model of prevention the addictions in children and adolescents. …”
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Effects of Prehabilitation With Advanced Technologies in Patients With Musculoskeletal Diseases Waiting for Surgery: Systematic Review and Meta-Analysis by Stefania Guida, Jacopo Antonino Vitale, Eva Swinnen, David Beckwée, Silvia Bargeri, Federico Pennestrì, Greta Castellini, Silvia Gianola

“…We found different prehabilitation programs: mindfulness-based stress reduction, exercise, education, or a combination thereof. …”
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Acute tuft cell ablation in mice induces malabsorption and alterations in secretory and immune cell lineages in the small intestine by Michael Momoh, Francisca Adeniran, Cynthia Ramos, Kathleen E. DelGiorno, Hiroshi Seno, Joseph T. Roland, Izumi Kaji

“…This study investigated the impact of acute tuft cell loss on intestinal physiological function. Tuft cell deletion was induced in DCLK1‐IRES‐GFP‐CreERT2/+;Rosa‐DTA (DCLK1‐DTA) mice by a single tamoxifen injection, concomitant with littermate controls. …”
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Analysis of the atomization performance of hydrodynamic rotating spray dust suppression device with setting fan by Hui XU, Qinghua CHEN, Dejun WANG

“…At the same time, the fan blade is set on the water shaft, so that the device has both rotating spray and negative pressure suction dust reduction functions; we build a coal mine dust experimental system, collect coal dust samples from Inner Mongolia 5013 excavation face, and measure the total dust and respiratory dust concentrations of three dust reduction schemes through CCZ-20A dust sampler. …”
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Eye movements during the Iowa Gambling Task in Parkinson’s disease: a brief report by Kirby Doshier, Anthony J. Ryals, Vicki A. Nejtek, Michael F. Salvatore, Jerome Lisk

“…Participants with PD and matched healthy controls completed the Movement Disorders Society’s modified Unified Parkinson’s Disease Rating Scale (UPDRS-MDS), 6-min Walk Test (6MWT), Timed Up and Go Test (TUG), Trail Making Test A and B (TMT A and B), Controlled Oral Word Association Test (COWAT), and the Barratt Impulsiveness Scale (BIS). …”
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Surface-Based Analyses of Anatomical Properties of the Visual Cortex in Macular Degeneration. by Doety Prins, Tina Plank, Heidi A Baseler, André D Gouws, Anton Beer, Antony B Morland, Mark W Greenlee, Frans W Cornelissen

“…In particular, new therapeutic strategies to restore retinal function rely on intact visual pathways and cortex to reestablish visual function. …”
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Selective Retention of an Inactive Allele of the DKK2 Tumor Suppressor Gene in Hepatocellular Carcinoma. by Yung-Feng Lin, Ling-Hui Li, Chih-Hung Lin, Mei-Hua Tsou, Ming-Tai Kiffer Chuang, Keh-Ming Wu, Tsai-Lien Liao, Jian-Chiuan Li, Wei-Jie Wang, Angela Tomita, Beverly Tomita, Shiu-Feng Huang, Shih-Feng Tsai

“…Taken together, the genotyping and functional findings are consistent with the hypothesis that DKK2 is a tumor suppressor; by selectively retaining a transcriptionally inactive DKK2 allele, the reduction of DKK2 function results in unchecked Wnt/β-catenin signaling, contributing to HCC oncogenesis. …”
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The in-vitro starch digestibility, pasting and antioxidant properties of the composite flour from cassava root and tigernut seed by Adeyemi Ayotunde Adeyanju, Darasimi Gift Adeleye, Johnson Akinwumi Adejuyitan, Eunice Ogunbusola, Oluwaseun Peter Bamidele

“…The composite flour formulations are cassava flour to tigernut flour ratios of 90:10, 80:20, 70:30, 60:40, and 50:50 together with 100% fermented cassava flour and 100% tigernut flour as control. The flour samples were evaluated for their functional properties, pasting behaviour, in vitro starch digestibility, total phenolic content, and radical scavenging activity. …”
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Experimental carotid baroreceptor stimulation reduces blood flow velocities in the anterior and middle cerebral arteries of healthy individuals by Gustavo A. Reyes del Paso, Casandra I. Montoro, J. Richard Jennings, Stefan Duschek

“…The findings underline the interaction between peripheral and cerebral hemodynamic regulation in autoregulatory control of cerebral perfusion.…”
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<i>N</i>-Acetylcysteine Treatment Restores the Protective Effect of Heart Ischemic Postconditioning in a Murine Model in the Early Stages of Atherosclerosis by Tamara Zaobornyj, Virginia Perez, Georgina Ossani, Tamara Mazo, Eugenia Godoy, Jorge Godoy, Yohana Yanaje, Camila Musci-Ferrari, Mario Contin, Valeria Tripodi, Magali Barchuk, Gabriela Berg, Ricardo J. Gelpi, Martin Donato, Veronica D’Annunzio

“…Infarct size, ventricular function, redox status (GSH/GSSG), lipid profile, and histology were evaluated. …”
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