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Evaluation of three-dose fosfomycin tromethamine in the treatment of patients with urinary tract infections: an uncontrolled, open-label, multicentre study
Published 2013-12-01“…Clinical symptoms, physical signs, urinalysis, liver and kidney function, patient records and evaluation of adverse events (AEs) and serious AEs up to day 15 were evaluated for analysis of safety.Results 361 patients were included in the full analysis set, 356 in the safety analysis set and 335 in the per-protocol set (PPS). …”
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62
Fibrin Clot Strength in Patients with Diabetes Mellitus Measured by Thrombelastography
Published 2018-01-01“…Patients with diabetes mellitus (DM) exhibit increased risk of recurrent myocardial infarction. Maximal clot strength measured by thrombelastography (TEG) is a risk factor for recurrent ischemic events. …”
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63
Intelligent Ensemble Deep Learning System for Blood Glucose Prediction Using Genetic Algorithms
Published 2022-01-01“…Although there are numerous deep learning algorithms available, this study applied five algorithms, namely, recurrent neural network (RNN), which is optimized for sequence data (e.g., time-series), and RNN-based algorithms (e.g., long short-term memory (LSTM), stacked LSTM, bidirectional LSTM, and gated recurrent unit). …”
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64
Computational pathology assessments of cardiac stromal remodeling: Clinical correlates and prognostic implications in heart transplantation
Published 2025-02-01“…Biopsy images were then analyzed to assess which historical inflammatory events drive progression of these pathologic stromal changes. …”
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65
The Prognostic Implication of the BRAF V600E Mutation in Papillary Thyroid Cancer in a Chinese Population
Published 2022-01-01“…Kaplan–Meier survival curves and Cox proportional hazards regression analysis were applied to implement the survival analysis. …”
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66
Dynamic multiday seizure cycles and evolving rhythms in a tetanus toxin rat model of epilepsy
Published 2025-02-01“…Six TT-injected rats were observed over a 40-day period, with continuous EEG monitoring to record seizure events. Wavelet transform analysis revealed significant multiday cycles in seizure occurrences, with periods ranging from 4 to 7 days across different rats. …”
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Efficacy and Safety of Dual Delayed-Release Formulation of Esomeprazole in Patients with Gastroesophageal Reflux Disease: A Multicenter, Prospective, Observational Study
Published 2025-01-01“…GERD-related symptoms and treatment-emergent adverse events were also analyzed. Results: This study included 5,282 patients in the safety analysis set and 5,232 in the full analysis set. …”
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68
Assessing the Return Periods and Hydroclimatic Parameters for Rainwater Drainage in the Coastal City of Cotonou in Benin under Climate Variability
Published 2023-01-01“…Determining return periods and these parameters requires statistical analysis of extreme events, and this analysis needs to be regularly updated in response to climate change. …”
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69
Potential of 6-mm-diameter fully covered self-expandable metal stents for unresectable malignant distal biliary obstruction: a propensity score-matched study
Published 2025-01-01“…Among the patients in the end-stage cohort who were unable to continue chemotherapy after FCSEMS deployment, the free rate of stent-related events, including recurrent biliary obstruction and stent-related AEs, was significantly higher in the 6-mm group (p=0.027). …”
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Plasma Levels of Propionylcarnitine Improved Prediction of Heart Failure and All-Cause Mortality in Patients with Stable Coronary Artery Disease
Published 2024-12-01“…Conclusions: Patients with SCAD led to recurrent HF or all-cause death. Interestingly, increased levels of plasma NGAL and Gal-3, and a reduction in propionylcarnitine, could predict the occurrence of these events.…”
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Response to induction chemotherapy as a prognostic indicator in locally advanced head and neck squamous cell carcinoma
Published 2024-12-01“…Tumor reduction of 30% or more was observed in 23 patients (69.7%), the tumor control rate was 97%. The 2-year event-free survival (EFS) in the IC evaluable population was 53.1%, overall survival (OS) was 63.6%, and recurrence-free survival (RFS) was 62.5%. …”
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72
Collaborative Governance in the Digital Transformation Age: A Systematic Literature Review with Bibliometric Mapping
Published 2023-05-01“…Digital transformation is a recurrent theme in today’s society, fuelled by events such as the Covid-19 pandemic, global climate challenges, and other crises reshaping the world. …”
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Pierre et carrières dans la Saintonge antique : identification, usages et diffusion
Published 2022-12-01“…The briefly described geomorphological history, underscores the Pyrenean orogeny, a major event which transformed the Aquitaine basin of the secondary era into the current sedimentary plateau. …”
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Four-year clinical update and treatment switching-adjusted outcomes with first-line nivolumab plus ipilimumab with chemotherapy for metastatic non-small cell lung cancer in the Che...
Published 2024-02-01“…We report updated efficacy and safety in all randomized patients with a minimum 4-year follow-up and an exploratory treatment-switching adjustment analysis in all treated patients who received chemotherapy and subsequent immunotherapy.Methods Adults with stage IV/recurrent non-small cell lung cancer (NSCLC), no sensitizing EGFR/ALK alterations, and ECOG performance status ≤1 were randomized 1:1 to nivolumab 360 mg every 3 weeks plus ipilimumab 1 mg/kg every 6 weeks with chemotherapy (two cycles) or chemotherapy (four cycles, with optional maintenance pemetrexed for the nonsquamous population). …”
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Elevated Plasma Soluble Triggering Receptor Expressed on Myeloid Cells-1 Level in Patients with Acute Coronary Syndrome (ACS): A Biomarker of Disease Severity and Outcome
Published 2021-01-01“…On logistic regression analysis, higher sTREM-1 levels predicted definite ACS vs. …”
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Evaluation of patient immunocompetence for immune checkpoint inhibitor therapy using the psoas muscle index: a retrospective cohort study
Published 2025-02-01“…IntroductionIn patients with cancer, sarcopenia is an indicator of poor prognosis and is associated with an increased risk of chemotherapy-related adverse events. Skeletal muscle interacts with the immune system, and sarcopenia is associated with immune senescence. …”
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Cardiovascular Profile and Cardiovascular Imaging After Bariatric Surgery: A Narrative Review
Published 2025-01-01“…Specifically, this procedure is linked to a lower occurrence of major adverse cardiovascular events and a decrease in overall mortality. Also, BaS is correlated with a reduced risk of recurrent MI and the development of new-onset heart failure. …”
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Somatic copy number deletion of chromosome 22q in papillary thyroid carcinoma
Published 2025-01-01“…Deletion of the long q arm of chromosome 22 (22qDEL) is the most frequently identified recurrent somatic copy number alteration observed in papillary thyroid carcinoma (PTC). …”
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Altered CD73-Adenosine Signaling Linked to Infection in Patients undergoing hemodialysis
Published 2025-01-01“…Diminished CD73-adenosine signaling contributes to severe infections.Methods: In this prospective cohort study, 393 patients who underwent HD for over six months were evaluated for CD73+Tcell ratios and were followed up for three years to track infection events. Kaplan–Meier curves and Cox regression analyses were used to evaluate the relationship between CD73+T cells and infections; meanwhile, multiple logistic regression analysis was used to analyze differences among infection groups. …”
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