Correction: A fully human IgG1 antibody targeting connexin 32 extracellular domain blocks CMTX1 hemichannel dysfunction in an in vitro model by Abraham Tettey-Matey, Viola Donati, Chiara Cimmino, Chiara Di Pietro, Damiano Buratto, Mariateresa Panarelli, Alberto Reale, Arianna Calistri, Maria Vittoria Fornaini, Ruhong Zhou, Guang Yang, Francesco Zonta, Daniela Marazziti, Fabio Mammano

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A combined therapy of inflammatory diseases of eyelids by E. V. Yani, K. E. Seliverstova

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Transforming Screening, Risk Stratification, and Treatment Optimization in Chronic Liver Disease Through Data Science and translational Innovation by Tamer A. Addissouky

“…Analyses revealing IL21R as a PBC susceptibility gene and implicating dysfunctional VWF processing in portal hypertension deliver mechanistic insights. …”
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Differential effects of β-blockers nebivolol and metoprolol on mitochondrial biogenesis and antioxidant defense in angiotensin II-induced pathology in H9c2 cardiomyoblasts by Rukhsana Gul, Arwa Bazighifan, Shahid Nawaz, Assim A. Alfadda

“…Western blotting and Real-time PCR were used to quantify protein and mRNA levels, respectively. …”
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AI-driven cognitive telerehabilitation for stroke: a randomized controlled trial by Suebeen Kim, Si-Woon Park, Si-Woon Park, Taeksoo Jeong, Min-Soo Kang, Doo Young Kim, Doo Young Kim

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Tricuspid regurgitation and chronic kidney disease in patients with cardiogenic shock: Review of the literature and real-world experience from a single center by Daniel Oren, Sunil Ramchandani, Adrian Lorenzana, Ranjit Nair, Julia Szinte, Kian Maalizadeh, Farage Ftiha, Cathrine M. Moeller, Andrea Fernandez-Valledor, Roi Bar Cohen, Ignacio Zepeda, Shudhanshu Alishetti, Nino Mihatov, Kumudha Ramasubbu, Ruth Minkin, Anthony Saleh, Manish A. Parikh, Franklyn Fenton, Stephen J. Peterson

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A multidimensional assessment of adverse events associated with paliperidone palmitate: a real-world pharmacovigilance study using the FAERS and JADER databases by Siyu Lou, Zhiwei Cui, Yingyong Ou, Junyou Chen, Linmei Zhou, Ruizhen Zhao, Chengyu Zhu, Li Wang, Zhu Wu, Fan Zou

“…Abstract Objective Paliperidone palmitate is a second-generation antipsychotic that has undergone extensive investigation in clinical trials. However, real-world studies assessing its safety in large populations are lacking. …”
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A real-world pharmacovigilance analysis of potential ototoxicity associated with sacubitril/valsartan based on FDA Adverse Event Reporting System (FAERS) by Ning Wang, Haijun Wang, Ying Chen, Yanfeng Wang

“…Despite its efficacy, sacubitril/valsartan inevitably causes adverse events such as hypotension, renal dysfunction, hyperkalemia, and angioedema. Sacubitril/valsartan-associated ototoxicity is often underreported in clinical studies and real-world settings. …”
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A real-world pharmacovigilance study of adverse drug reactions associated with lecanemab and aducanumab based on WHO-VigiAccess and FAERS databases by Haoxiang Hu, Yunhan Zhao, Jiesheng Mao, Jianghai He, Yihan Zhang, Hongyu Ye, Xiaokai Yang

“…However, thrombocyto-penia was more prevalent in Lecanemab, while platelet dysfunction and myelosuppression were more frequently observed in Aducanumab. …”
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Prospective Cohort Study of Trastuzumab Biosimilar CT-P6 in HER2-Positive Gastric Cancer: Japanese Real-World Outcomes by Hiroya Taniguchi, Kiyohiro Nishikawa, Tatsuo Haneji, Naoki Izawa, Hiroshi Imamura, Hironori Yamaguchi

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Identification of Exhaled Metabolites Correlated with Respiratory Function and Clinical Features in Adult Patients with Cystic Fibrosis by Real-Time Proton Mass Spectrometry by Malika Mustafina, Artemiy Silantyev, Stanislav Krasovskiy, Alexander Chernyak, Zhanna Naumenko, Aleksandr Suvorov, Daria Gognieva, Magomed Abdullaev, Olga Suvorova, Anna Schmidt, Aida Gadzhiakhmedova, Aleksandra Bykova, Sergey Avdeev, Vladimir Betelin, Abram Syrkin, Philipp Kopylov

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BRCA1 regulates glucose and lipid metabolism in diabetes mellitus with metabolic dysfunction-associated steatotic liver disease via the PI3K/Akt signaling pathway. by Cui Ma, Xiaodi Yang, Liyin Zhang, Jie Zhang, Youyou Zhang, Xiaofeng Hu

“…<h4>Purpose</h4>This study mimics the metabolic environment of metabolic dysfunction-associated steatotic liver disease (MASLD) and diabetic mellitus (DM) to investigate the function of BRCA1 in regulating glucose and lipid metabolism in hepatocytes under high glucose (HG) settings.…”
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Random forest-driven mortality prediction in critical IBD care: a dual-database model integrating comorbidity patterns and real-time physiometrics by Zhenze Zhang, Zhenze Zhang, Caiqing Zhao, Caiqing Zhao, Yijun Zhou, Ling Yao, Peng Liu, Ziling Fang, Nian Fang, Nian Fang

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Evaluating Renal Benefits of Rivaroxaban Versus Vitamin K Antagonists in Atrial Fibrillation: A Systematic Review and Meta-analysis of Real-world Evidence by Phong Phan Dinh, Tri Huynh Quang Ho, Hung Manh Pham, Hai Hoang Nguyen, Minh That Ton, Giang Song Tran, Nga Quynh Vu, Hung Nhu Pham, Son Cao Luong, Sy Van Hoang

“…Background: AF is a global health concern, with systemic complications including renal dysfunction. This systematic review and meta-analysis compares the effects of rivaroxaban, a Factor Xa inhibitor, and vitamin K antagonists (VKAs) on renal outcomes in AF patients. …”
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Activation of spinal PGC-1α regulates microglial polarization through a feedback loop between ROS-mediated mitochondrial dysfunction and the NLRP3 inflammasome in neuropathic pain by Yanhua Chen, Guoxu Ling, Qingling Xu, Qiulin Zhu, Tonghong Huang, Tingting Su, Yubo Xie, Yu Zhong

“…Western blotting and immunofluorescence were used to examine the expression of target proteins. Quantitative real-time PCR (qPCR) was used to investigate the mitochondrial DNA copy number (mtDNA). …”
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Co-expression of LncRNA and mRNA in the cumulus-oocyte complex of rabbits exposed to ammonia by Jia Cui, Fengyang Wu, Xinyu Yang, Yanhua Liu, Shudong Liu, Shuaijuan Han, Jiawei Guo, Baojiang Chen

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Divergent psychological stress response patterns to the COVID-19 pandemic in psychiatric patients with vs. without PTSD: A real-world exploratory study. by Marit Treptow, Claudia Bartels, Mirjana Ruhleder, Alexander Kratzenberg, Thorgund Reh-Bergen, Mona Abdel-Hamid, Luisa Heß, Jörg Signerski-Krieger, Katrin Radenbach, Björn-Hendrik Schott, Jens Wiltfang, Claus Wolff-Menzler, Ulrike Schmidt, Michael Belz

“…In particular, it remains unclear which pandemic-related stress response pattern occurs in pre-existing posttraumatic stress disorder (PTSD) during the pandemic - at the same time these patients potentially exhibit dysfunctional coping of artificially generated psychosocial stressors. …”
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Real-World Outcomes of Allogeneic Immunosafe Plasma Rich in Growth Factors Eye Drops for Refractory Ocular Surface Diseases: A Prospective Observational Study by Rosa Alvarado-Villacorta, Jesús Merayo-Lloves, Ronald M. Sánchez-Ávila, Belén Alfonso-Bartolozzi, Carlos Lisa, Luis Fernández-Vega-Cueto, José F. Alfonso, Eduardo Anitua

“…We aimed to evaluate the safety and clinical outcomes of allogeneic is-ePRGF therapy for refractory OSD in real-world practice. Methods A single-center cohort was conducted involving consecutive patients with severe OSD nonresponsive to conventional therapy. …”
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Detailed Command vs. Mission Command: A Cancer-Stage Model of Institutional Decision-Making by Rodrick Wallace

“…The resulting probability models can, with some effort, be converted into new statistical tools for analysis of real time, real world data involving cognitive phenomena and their dysfunctions across a considerable range of scales and levels of organization.…”
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Long Neuro-COVID-19: Current Mechanistic Views and Therapeutic Perspectives by Anny Slama Schwok, Julien Henri

“…Long-lasting COVID-19 (long COVID) diseases constitute a real life-changing burden for many patients around the globe and, overall, can be considered societal and economic issues. …”
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