POLYMORPHISM OF THE HAEMOSTASIS GENES IN WOMEN WITH THREATENED PRETERM DELIVERY by A. I. Malyshkina, I. N. Fetisova, Yu. N. Zholobov, A. O. Nazarova, S. Yu. Ratnikova, N. S. Fetisov, S. B. Nazarov

“…The observed accumulation of polymorphic genes may play a role in hemostasis dysfunction, which affects the blood fibrinolytic activity. …”
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Validation of quantitative hepatitis B virus DNA and hepatitis B e antigen titers in patients of chronic hepatitis B virus infection on entecavir therapy at tertiary care hospital by Diksha Budhani, Varsha A Singh, Madhurendra Singh Rajput, Varsha Saxena, Pooja Sindwani

“…Screening of HBsAg was performed using rapid card test method, HBeAg was done by enzyme-linked immunosorbent assay, and HBV DNA was quantified by real-time polymerase chain reaction. Aspartate aminotransferase and ALT were also measured. …”
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Effect of multiple neonatal sevoflurane exposures on hippocampal apolipoprotein E levels and learning and memory abilities by Junli Jiang, Chunchun Tang, Juanjuan Ren, Chao Zhang, Liang Dong, Zhaoqiong Zhu

“…In this study, we investigated whether early multiple exposures to sevoflurane induced cognitive dysfunction by altering the hippocampal expression of ApoE later in development. …”
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Clinical and Biological Characteristics of Four Patients with Aggressive Systemic Mastocytosis Treated with Midostaurin by Delia Soare, Dan Soare, Camelia Dobrea, Eugen Radu, Horia Bumbea

“…We report a case series of four patients diagnosed with ASM to highlight the real-world experience in the management of ASM. All patients had confirmed <i>KIT</i> D816V mutations and presented with signs of advanced organ dysfunction, such as marked hepatosplenomegaly, cytopenia, and significant bone marrow infiltration. …”
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PDZD8 Augments Endoplasmic Reticulum-Mitochondria Contact and Regulates Ca2+ Dynamics and Cypd Expression to Induce Pancreatic β-Cell Death during Diabetes by Yongxin Liu, Yongqing Wei, Xiaolong Jin, Hongyu Cai, Qianqian Chen, Xiujuan Zhang

“…PDZD8 expression was detected using immunohistochemistry, quantitative real-time polymerase chain reaction (qRT-PCR), and Western blotting. …”
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Inhibition of miRNA-155 Alleviates High Glucose-Induced Podocyte Inflammation by Targeting SIRT1 in Diabetic Mice by Xiaolei Wang, Yanbin Gao, Wenming Yi, Yu Qiao, Hao Hu, Ying Wang, Yan Hu, Shuxin Wu, Hongfeng Sun, Taojing Zhang

“…Microinflammation plays a crucial role in podocyte dysfunction in diabetic nephropathy, but its regulatory mechanism is still unclear. …”
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MicroRNA in Sjögren’s Syndrome: Their Potential Roles in Pathogenesis and Diagnosis by M. Reale, C. D’Angelo, E. Costantini, M. Laus, A. Moretti, A. Croce

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The Effect of the Antidepressant Citalopram on the Bioconcentration and Biomarker Response of <i>Daphnia magna</i> at Environmentally Relevant Concentrations by Haohan Yang, Jiacheng Tan, Hanyu Jiang, Hao Xing, Jingnan Zhang, Dexin Kong, Zhuoyu Chen, Linghui Kong

“…This study provided basic data for the risk estimation of CIT in the real freshwater environment.…”
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Gender Differences of Gly972Arg Polymorphism of the IRS-1 Gene Related to Cardiovascular Disease Risk Factors Among Indonesians by Renan Sukmawan, Harry Mahathir Akip, Priyandini Wulandari, Evans T Bobians, BRM Ario Soeryo Koencoro, Siska Suridanda Danny, Ade Meidian Ambari, Sunu Budhi Raharjo, Bambang Widyantoro, Suko Adiarto

“…Gly972Arg polymorphism of the IRS-1 gene (rs1801278) was detected using TaqMan real-time polymerase chain reaction. Results: A total of 378 subjects were recruited. …”
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Extracellular Vesicles Derived from FGF2-Primed Astrocytes Against Mitochondrial and Synaptic Toxicities in Parkinson&rsquo;s Disease by Wen X, Cao W, Ding H, Chen A, Sun Z, Wang Y, Xi Y, Wu S

“…Mitochondrial alterations, neuronal survival, synaptogenesis, and mice behavior were subsequently evaluated by quantitative real-time polymerase chain reaction, Western-blotting, immunohistochemistry, and CatWalk gait analysis. …”
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The Effect of Virtual Reality Training on Anticipatory Postural Adjustments in Patients with Chronic Nonspecific Low Back Pain: A Preliminary Study by Zhicheng Li, Qiuhua Yu, Haizhen Luo, Wenzhao Liang, Xin Li, Le Ge, Siyun Zhang, Le Li, Chuhuai Wang

“…Besides magnetic therapy, the participants in the MCE group performed real-time ultrasound-guided abdominal drawing-in maneuver (ADIM) and four-point kneeling exercise. …”
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Exploring Oxidative Stress Mechanisms of Nanoparticles Using Zebrafish (<i>Danio rerio</i>): Toxicological and Pharmaceutical Insights by Denisa Batir-Marin, Monica Boev, Oana Cioanca, Ionut-Iulian Lungu, George-Alexandru Marin, Ana Flavia Burlec, Andreea-Maria Mitran, Cornelia Mircea, Monica Hancianu

“…This redox imbalance, primarily driven by the overproduction of reactive oxygen species (ROS), plays a central role in NP-induced toxicity, leading to cellular dysfunction, inflammation, apoptosis, and genotoxicity. …”
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NLRP3 Mediates NOXs-Induced Iron Overload and Inflammation but Not Oxidative Damage in Colons of DSS-Treated Mice by Yu L, Wang M, Zhou Y, Qi J, Zheng Q, Song Z

“…Measurements such as weight, disease activity index, HE staining, Prussian blue staining, immunohistochemical and immunofluorescence, ELISA, flow cytometry detection, Western blot, and Quantitative Real-Time PCR were conducted.Results: Chemical inhibition of NOXs and NLRP3 in vivo could significantly reduce colonic iron overload and macrophage infiltration, thus alleviating colonic inflammatory response and tissue damage. …”
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Capillary refill time and tissue oxygen saturation as factors influencing lower limb ischemia in VA-ECMO: a case-control study by Zhenjia Liu, Lin Han, Li Mo, Guangbao Pang, Zhongzhi Xie, Zhai Huang

“…Conclusions StO2 reflects real-time tissue perfusion adequacy, whereas CRT serves as a marker of microvascular dysfunction. …”
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Pro-Inflammatory Properties of Salivary Gland-Derived Fibroblasts—Implications in Sjögren’s Disease by Matthias Brunner, Daniel Guggisberg, Marco Sprecher, Ondrej Pastva, Kristina Bürki, Miranda Houtman, Marco Kreuzer, Sara Andrea Krättli, Laura Jahnke, Mila Roceri, Rémy Bruggmann, Muriel Elhai, Britta Maurer, Thomas M. Marti, Caroline Ospelt, Kerstin Klein

“…Salivary gland dysfunction is a hallmark of Sjögren’s disease (SjD). …”
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Delving into the Perception, Use, and Context of Duloxetine in Clinical Practice: An Analysis Based on the Experience of Healthcare Professionals by Oscar Fraile-Martinez, Cielo Garcia-Montero, Miguel Angel Alvarez-Mon, Miguel A. Ortega, Melchor Alvarez-Mon, Javier Quintero

“…To address this knowledge gap, we conducted a cross-sectional observational study involving 80 psychiatrists from Spain to assess real-world clinical attitudes toward duloxetine. …”
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AI-Enhanced 3D Transperineal Ultrasound: Advancing Biometric Measurements for Precise Prolapse Severity Assessment by Desirèe De Vicari, Marta Barba, Alice Cola, Clarissa Costa, Mariachiara Palucci, Matteo Frigerio

“…AI integration facilitated real-time image segmentation and automated measurement, reducing operator dependency and increasing reproducibility. …”
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The effects of treadmill exercise and diet control on cognitive function in HFD-induced ApoE-/- mice based on the SIRT1-NF-κB/PGC-1α-BDNF signaling pathways by Xu Ting, Deng Wenjuan, Li Shufeng, Liu Yi, Shi Zhitong, Zhang Xiaoyue, Wang Ningping

“…[Objective] To investigate the effect and mechanism of treadmill exercise and diet control on cognitive dysfunction in apolipoprotein E knockout(ApoE-/-)mice model. …”
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Linking oxysterols and different stages of mild cognitive impairment: insights from gut metabolites and N6-methyladenosine by Wenjing Feng, Mengwei Ju, Tao Wang, Shanshan Cui, Kexin Yang, Zhiting Guo, Miao Liu, Jiaxuan Tao, Huiyan Yu, Rong Xiao

“…Abstract Background Oxysterols, gut metabolites, and N6-methyladenosine (m6A) are extensively implicated in the pathogenesis of cognitive dysfunction, while their alterations in different stages of mild cognitive impairment (MCI) have not been elucidated. …”
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Mito-fission gene prognostic model for colorectal cancer by Chao Liu, Sheng Xu, Yuanyuan Liu, Zhixing Lu, Jianrong Yang

“…Therefore, this study focuses on the specific regulatory mechanisms of mitochondrial dysfunction on CRC, which will provide theoretical guidance for CRC in the future. …”
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