Etiology and Pathogenesis of Postoperative Cognitive Dysfunction (Review) by M. I. Neimark, V. V. Shmelev, A. A. Rakhmonov, Z. A. Titova

“…Postoperative cognitive dysfunction significantly challenges patients’ quality of life, negating real success of surgical intervention and anesthetic support. …”
Get full text

Prospective study of continuous rhythm monitoring in patients with early post-infarction systolic dysfunction: clinical impact of arrhythmias detected by an implantable cardiac monitoring device with real-time transmission—the TeVeO study protocol by Jesus Hernandez-Hernandez, Ana Martin-Garcia, Javier Jimenez-Candil, Pedro L Sanchez, Carlos González-Juanatey, Javier García-Fernández, Alba Cruz-Galban, Olga Duran-Bobin, Javier Garcia-Seara, Teba Gonzalez-Ferrero, Jose Morinigo, Manuel Sanchez-Garcia, Gonzalo Fernandez-Palacios, Jose Seijas-Amigo, Juliana Elices, Javier Portales-Fernandez, Francisco Martin-Herrero, Ana García-Campos, Jose A Perez-Rivera, Marta Alonso-Fernandez-Gatta, Alfonso Macías, Paloma Perez-Espejo

“…Each patient will be informed about the study in both oral and written form by a physician and will be included in the study after written consent is obtained.For the first time, a study will provide real-time information on the arrhythmic burden of patients with post-infarction ventricular dysfunction and its prognostic implications in the medium term. …”
Get full text

Urinary Catheter Causing Paracentesis-induced Circulatory Dysfunction by José Guilherme Assis, Joana Rua

Get full text

Erectile Dysfunction and Hypertension: Impact on Cardiovascular Risk and Treatment by Valter Javaroni, Mario Fritsch Neves

“…On the other hand, the real influence of antihypertensive drugs in erectile function still deserves discussion. …”
Get full text

Circulating angiogenic cell dysfunction in patients with hereditary hemorrhagic telangiectasia. by Liana Zucco, Qiuwang Zhang, Michael A Kuliszewski, Ivana Kandic, Marie E Faughnan, Duncan J Stewart, Michael J Kutryk

Get full text

Development of SOCS1 mimetics as novel approach to harmonize inflammation, oxidative stress, and fibrogenesis in metabolic dysfunction-associated steatotic liver disease by Susana Bernal, Ignacio Prieto, María Kavanagh, Isabel Herrero del Real, Sara La Manna, Iolanda Lázaro, Hernán Quiceno, Laura López-Sanz, Belén Picatoste, M. Pilar Valdecantos, Sebastián Mas-Fontao, Aleix Sala-Vila, Ángela M. Valverde, Daniela Marasco, Jesús Egido, Carmen Gómez-Guerrero

Get full text

Chain length-dependent mitochondrial toxicity of perfluoroalkyl carboxylic acids: insights from Mito Tox Index evaluation by Yoonseok Kam, Lisa Winer, Natalia Romero

Subjects: Get full text

Obesity Related Coronary Microvascular Dysfunction: From Basic to Clinical Practice by K. Selthofer-Relatić, I. Bošnjak, A. Kibel

“…From a clinical point of view it can present itself in acute or chronic form with different prognosis, as a practice problem for real-life diagnosis and treatment.…”
Get full text

Survey on Sildenafil, Tadalafil, and Vardenafil Concentrations in Food Supplements for Erectile Dysfunction by Elina Petkova-Gueorguieva, Stanislav Gueorguiev, Hristina Lebanova, Vasil Madzharov, Anna Mihaylova

“…Many violations and discrepancies between the label information and the real composition of the FS were identified. 70% of the samples contained undeclared ingredients of an erectile dysfunction medicinal product. …”
Get full text

The Relationship of Endothelial Dysfunction with the Development of Diastolic Heart Failure in Patients with Hypertension by T. V. Kalinkina, N. V. Lareva, M. V. Chistyakova, V. V. Gorbunov

“…Frequency distribution of alleles and genotypes: 1 mutation nitric oxide synthase 3 gene NOS3 -786 T>C; (С-786Т) in relation to indicators of left ventricular myocardial deformity was analyzed in hypertensive patients with or without diastolic dysfunction as well as in the control group. Polymerase chain reaction with detection of amplification product in real time (RCR-rt) or electrophoresis in agarose gel on genomic DNA of peripheral blood leukocytes were used for studying gene mutations.Results. …”
Get full text

POSTOPERATIVE COGNITIVE DYSFUNCTION – WHAT WE KNOW AND WHERE WE GO by Yu. S. Polushin, A. Yu. Polushin, G. Yu. Yukina, M. V. Kozhemyakina

“…The authors reviewed the literature and presented results of their own research of post-operative cognitive dysfunction confirming its social importance. The development of post-operative cognitive dysfunction is to be perceived as a real fact despite the differences in the published epidemiological data. …”
Get full text

Best practices in the management of thyroid dysfunction induced by immune checkpoint inhibitors by Ichiro Yamauchi, Daisuke Yabe

Get full text

Possibility of Using NO Modulators for Pharmacocorrection of Endothelial Dysfunction After Prenatal Hypoxia by Igor Belenichev, Olena Popazova, Oleh Yadlovskyi, Nina Bukhtiyarova, Victor Ryzhenko, Sergii Pavlov, Valentyn Oksenych, Oleksandr Kamyshnyi

“…Prenatal hypoxia (PH) is a key factor in the development of long-term cardiovascular disorders, which are caused by various mechanisms of endothelial dysfunction (ED), including those associated with NO deficiency. …”
Get full text

ALKBH5 modulation of ferroptosis in recurrent miscarriage: implications in cytotrophoblast dysfunction by Chuanmei Qin, Jiayi Wu, Xiaowei Wei, Xueqing Liu, Yi Lin

Get full text

Lymphoproliferative disorders and renal dysfunction: a case of CLL-related AKI by Akhil Tomy, Aswathi Balakrishnan, Siva Shrikanth, Cristoss Gregory, Maria Elizabeth John, Tanushree Dewan

“…A renal biopsy was performed under real-time ultrasound guidance, showing a prominent lymphocytic infiltrate with evidence of mild chronic renal damage.1 Immunohistochemistry identified small lymphocytes with lambda light chain restriction.2 The patient started treatment with acalabrutinib after discussions with the All-Wales Lymphoma panel. …”
Get full text

Enhancing Hand Sensorimotor Function in Individuals with Cervical Spinal Cord Injury: A Novel Tactile Discrimination Feedback Approach Using a Multiple-Baseline Design by Ken Kitai, Kaichi Nishigaya, Yasuhisa Mizomoto, Hiroki Ito, Ryosuke Yamauchi, Osamu Katayama, Kiichiro Morita, Shin Murata, Takayuki Kodama

Subjects: Get full text

A Real-World Experience With Resmetirom: Tolerability and Access by Sameera Shuaibi, Ian Tobal, James Gore, Ruona Ebiai, Claire Ozoral, George Therapondos

Get full text

Lack of sexual dimorphism in a mouse model of isoproterenol-induced cardiac dysfunction. by Marianne K O Grant, Ibrahim Y Abdelgawad, Christine A Lewis, Davis Seelig, Beshay N Zordoky

“…Intriguingly, gonadectomy of male and female mice did not have a significant impact on isoproterenol-induced cardiac dysfunction as compared to sham-operated animals. The current work demonstrated lack of significant sex-related differences in isoproterenol-induced cardiac hypertrophy, dysfunction, and fibrosis in C57Bl/6NCrl mice. …”
Get full text

Expression changes and functional role of GPR110 in metabolic dysfunction-associated steatohepatitis by Ting HONG, Xiaoying LI

“…MethodsHuman MASH liver tissues were collected for GPR110 detection via real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR) and immunohistochemistry. …”
Get full text

The effectiveness of complex treatment of endothelial dysfunction in patients with primary open angle glaucoma by A. M. Dusmukhamedova, D. M. Tuychibaeva, A. A. Khadzhimetov

Get full text