Suppression of Spry1 reduces HIF1α-dependent glycolysis and impairs angiogenesis in BRAF-mutant cutaneous melanoma by Barbara Montico, Giorgio Giurato, Roberto Guerrieri, Francesca Colizzi, Annamaria Salvati, Giovanni Nassa, Jessica Lamberti, Domenico Memoli, Patrizia Sabatelli, Marina Comelli, Arianna Bellazzo, Albina Fejza, Lucrezia Camicia, Lorena Baboci, Michele Dal Bo, Alessia Covre, Tuula A. Nyman, Alessandro Weisz, Agostino Steffan, Michele Maio, Luca Sigalotti, Maurizio Mongiat, Eva Andreuzzi, Elisabetta Fratta

“…The Seahorse XF24 assay allowed real-time measurement of cellular metabolism in our model. …”
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Digital Therapeutics–Based Cardio-Oncology Rehabilitation for Lung Cancer Survivors: Randomized Controlled Trial by Guangqi Li, Xueyan Zhou, Junyue Deng, Jiao Wang, Ping Ai, Jingyuan Zeng, Xuelei Ma, Hu Liao

“…Artificial intelligence–driven exercise prescription with a video guide and real-time heart rate (HR) monitoring was generated based on cardiopulmonary exercise testing. …”
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Sodium-Glucose Cotransporter-2 Inhibitor in Diabetic and Nondiabetic Renal Transplant Recipients by Lucie Maigret, Lucile Basle, Valérie Chatelet, Laure Ecotiere, Peggy Perrin, Léonard Golbin, Dominique Bertrand, Dany Anglicheau, Coralie Poulain, Cyril Garrouste, Clément Danthu, Charlotte Boud'hors, Yannick Le Meur, Manon Dekeyser, Fabien Duthe, Bénédicte Sautenet, Pierre-Guillaume Deliège, Philippe Gatault

“…Methods: This was a prospective multicenter real-life study including all consecutive KTRs treated with SGLT2i. …”
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Functioning in patients with major depression treated with duloxetine or a selective serotonin reuptake inhibitor in East Asia by Novick D, Montgomery W, Haro JM, Moneta MV, Zhu G, Yue L, Hong J, Duenas H, Brugnoli R

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Inhibition of histone deacetylases 3 attenuates imiquimod-induced psoriatic dermatitis via targeting cGAS-STING signaling in keratinocytes by Chong Zeng, Xiujuan Wen, Zibo Wei, Xinhuai Dong

“…Subsequently, we employed a combination of cellular and molecular techniques, including hematoxylin and eosin (H&E) staining, immunohistochemistry, flow cytometry, quantitative real-time PCR (qRT-PCR), western blotting, and transmission electron microscopy (TEM), to analyze the role of HDAC3 in IMQ-induced psoriasis-like inflammation in mice and in vitro psoriasis models. …”
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Clinical and laboratory profile of patients with positive direct antiglobulin test attended at a university hospital in Goias, Brazil by Isadora Cristina Mendes, Pâmela Cristina Gomes Farias de Assis, Raíssa Santos de Almeida, Luma Romeiro Rodrigues de Sousa, Lilian Carla Carneiro, Rosália Santos Amorim Jesuino

“…For the remaining patients, the most common symptoms were severe thrombocytopenia, anemia, renal dysfunction, fever, myalgia, headache, thrombosis, asthenia, hematuria and joint pain. …”
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A novel cuproptosis-associated LncRNA model predicting prognostic and immunotherapy response for glioma by Bo Lei, Ao zhan, Guoliang You, Honggang Wu, Shu Chen, Daobao Zhang, Zhiye Liu, Niandong Zheng

“…Additionally, the expression levels of the 10 signature genes were validated by quantitative real-time polymerase chain reaction (qRT-PCR).…”
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The study of miR-130a expression and its mechanism of action in peripheral blood endothelial progenitor cells (EPCs) in type 2 diabetes mellitus (T2DM) by Yawei Cai, Yao Zhu, Ning Xu, Tongen Chen

“…In this study, we aim to investigate the potential involvement of the TGFβ1/miR-130a/IL-18 axis underlying the dysfunction of endothelial progenitor cells (EPCs) in T2DM patients. …”
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Association between long-term visit-to-visit resting heart rate variability and cognitive decline: evidence from two national cohorts by Guangjun Zheng, Biying Zhou, Zhenger Fang, Xia Chen, Mingliang Liu, Fudong He, Haofeng Zhang, Guang Hao, Haidong Zhu, Yanbin Dong

“…This study aimed to examine the association between long-term visit-to-visit resting heart rate variability (RHRV) and cognitive dysfunction among the general population. Methods Data was derived from the Health and Retirement Study (HRS) and the China Health and Retirement Longitudinal Study (CHARLS). …”
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The role of PKM2-mediated metabolic reprogramming in the osteogenic differentiation of BMSCs under diabetic periodontitis conditions by Yanlin Zhu, Yuhan Yang, Yuyan Lan, Zun Yang, Xiang Gao, Jie Zhou

“…Gene and protein expression were analyzed by quantitative real-time PCR and western blotting. In vivo therapeutic effects of shikonin were validated via micro-CT and histological staining in a diabetic periodontitis mouse model. …”
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Role of joint interactions in upper limb joint movements: a disability simulation study using wearable inertial sensors for 3D motion capture by Nishtha Bhagat, Preeti Raghavan, Vikram Kapila

“…Abstract Background Restriction of movement at a joint due to disease or dysfunction can alter the range of motion (ROM) at other joints due to joint interactions. …”
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Effect of miR-1285-3p as a diagnostic biomarker for chronic heart failure on vascular endothelial cells by Chongyang Zhang, Jiazhen He, Dan Xiong, Yi Mei, Yao Zhu, Pan Deng, Yang Duan

“…Methods Total RNA was extracted from plasma samples of 106 CHF patients and 106 healthy individuals. Quantitative Real-time PCR (qRT-PCR) was used to detect the expression of miR-1285-3p. …”
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Exploration of the ubiquitination-related molecular classification and signature to predict the survival and immune microenvironment in colon cancer by Ji-Zhong Xu, Tian-Qi Wan, Jin-Song Su, Jun-Min Song

“…The early diagnostic value of four URGs was confirmed via quantitative real-time polymerase chain reaction (qRT-PCR) and immunohistochemistry. …”
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Emotional Experience and Consequences of Growing Up in a Family with Alcoholism in Adult Children of Alcoholics by Barbara Simonič, Elżbieta Osewska

“…Adult children of alcoholics often have problems in experiencing and regulating their emotions, as they had to carry many emotional burdens in a dysfunctional family, while they had no real opportunity for the healthy development of emotional regulation. …”
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Is colloidal oat an effective emollient ingredient for the prevention and treatment of atopic dermatitis in infants? by Joseph F. Fowler, Lin Ma, James Bergman, Paul Horowitz, Tina Lavender, Lawrence F. Eichenfield, Zoe Draelos, Simon G. Danby, Michael J. Cork

“…Background Atopic dermatitis (AD) is a chronic inflammatory skin condition characterized by barrier dysfunction and immune dysregulation, often leading to increased allergen penetration, sensitization, and secondary infections. …”
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Artesunate alleviates cerebral ischemia/reperfusion injury by suppressing FUNDC1-mediated excessive mitophagy by Fei Wang, Wenji Zhou, Liqing Huang, Li Sun, Lujun Deng, Liping Li

“…Mitophagy was analyzed by transmission electron microscope, mitochondrial membrane potential detection, western blotting, and real-time quantitative polymerase chain reaction (RT-qPCR). …”
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The development of postoperative pain in patients with late-stage knee osteoarthritis is associated with impaired metabolism and transport of fatty acids in blood cells by E. B. Chetina, G. A. Markova, K. E. Glemba, M. A. Makarov

“…Total RNA isolated from blood was used to determine the expression of ACLY, ACC1, MLYCD, FASN and CPT1A genes by real-time quantitative reverse transcriptase-polymerase chain reaction.   …”
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Electrophysiological signs of retinal cone remodeling in geographic atrophy of the pigment epithelium in patients with non-exudative age-related macular degeneration by N. V. Neroeva, M. V. Zueva, V. V. Neroev, I. V. Tsapenko, M. V. Ryabina, O. A. Losanova, L. A. Katargina

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Membrane Permeability Monitoring to Antipsychotic Olanzapine Using Platinum Black-Modified Electrodes by Murugaiya Sridar Ilango, Dayananda Desagani, Srikanth Jagadeesan, Alexander Snezhko, Gad Vatine, Hadar Ben-Yoav

“…The blood–brain barrier (BBB) is key to the regular functioning of the central nervous system. The dysfunction of the BBB has been described in various neurological disorders, including schizophrenia. …”
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Full-length 16S rRNA Sequencing Reveals Gut Microbiome Signatures Predictive of MASLD in children with obesity by Yu-Cheng Lin, Chi-Chien Wu, Yun-Er Li, Chun-Liang Chen, Chia-Ray Lin, Yen-Hsuan Ni

“…Abstract Background The gut microbiota plays a crucial role in metabolic dysfunction-associated steatotic liver disease (MASLD). …”
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