Comprehensive Approach to Developing Baseline Reference Ranges for Platelet Function by Olga B. Gordeeva, Maria S. Karaseva, Vasily A. Lastovka, Nato D. Vashakmadze, Margarita A. Soloshenko, Gregory V. Revunenkov, Kirill A. Valyalov, Viktor V. Altunin

“…Thrombocytopathies are topical issues of pediatrics. Platelet dysfunction clinically manifests as thrombotic and hemorrhagic events of various severity and location. …”
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Impaired hypoglycemia awareness in diabetes: epidemiology, mechanisms and therapeutic approaches by Vadim V. Klimontov

“…The IAH is associated with episodes of severe hypoglycemia, fear of hypoglycemia and cognitive dysfunction. These associates can be combined into IAH syndrome. …”
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Cardiotoxicity of Chemotherapeutic Drugs (Literature Review and Clinical Case Description) by Avagimyan Ashot A., Mkrtchyan Lusine G.

“…However, acute cardiac dysfunction may also reflect the damage of myocytes, which may ultimately develop into early or late cardiotoxicity. …”
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Manganese‐enhanced MRI during remotely induced myocardial ischemia reperfusion injury in male mice by Matic Pusovnik, Michiel Algoet, Willy Gsell, Stefan Janssens, Wouter Oosterlinck, Uwe Himmelreich

“…Our remote occlusion technique facilitates real‐time perfusion assessments, enhancing preclinical myocardial ischemia studies.…”
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RNA Interference-Mediated Downregulation of sAC Gene Inhibits Sperm Hyperactivation in Male Rats (Rattus norvegicus) by Jing YU, Xiao-qiang JIANG, Shuai ZHOU, Gen-lin WANG

“…Cultured for 12 and 24 h, physiological and biochemical indexes of these sperm were analyzed, and the expressions of some hyperactivation-related genes were detected using real-time PCR. We demonstrated 26.3–30.8% and 49.1–50.5% reduction in sAC at the protein by Western blot and mRNA levels by real-time PCR, respectively. …”
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Plumbagin ameliorates ferroptosis of ovarian granulosa cells in polycystic ovary syndrome by down-regulating SLC7A5 m6A methylation modification through inhibition of YTHDF1 by ZhaoWei Cai, RuoPeng Zhang, RongJu Liu, Li Zhao, LiLing Zhou

“…Fluorescence in situ hybridization, RNA immunoprecipitation, and m6A quantitative real-time polymerase chain reaction verified the interaction and translational regulation of YTHDF1 and SLC7A5. …”
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Evaluation of feeding difficulties using videofluoroscopic swallow study and swallowing therapy in infants and children by Yun Chou, Lan-Wan Wang, Chien-Jen Lin, Lin-Yu Wang, Wen-Hui Tsai, Mei-Ju Ko

“…Videofluoroscopic swallow study (VFSS) is a useful tool for real-time visualization of the swallowing process and airway aspiration. …”
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Mitotherapy attenuates sepsis-induced brain injury in rats subjected to cecal ligation and puncture: Role of SIRT-1/PGC-1α network by Behnaz Mokhtari, Alireza Alihemmati, Soleyman Bafadam, Solmaz Boraghi, Reza Badalzadeh, Ata Mahmoodpoor

“…Objective(s): Sepsis-induced brain injury poses a critical challenge with limited therapeutic options. Mitochondrial dysfunction is a central contributor to this pathogenesis. …”
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Thoracic Sonography - An Overview by Jean-Luc Kurzen, Maik Häntschel

“…Thoracic sonography allows for a fast real-time analysis of thoracic pathologies. In addition to diagnosing pleural effusions, it can also identify diaphragmatic dysfunction, pulmonary consolidations, tumors, empyema, abscesses, rib fractures, and thoracic lymphadenopathies without radiation exposure and further specification. …”
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Extra-aural disorders in patients with acoustic trauma who were in the zone of the antiterrorist operation. by T. A. Shidlovs’ka, L. G. Petruk

“…Increased number of auditory system damage resulting from mine blast and other types of acoustic trauma, including those received in real combat conditions, makes the demand to provide quick and timely support to such patients. …”
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Burden of hypereosinophilic syndromes in the United States: Patients’ perspective by Jared Silver, MD, PhD, Anna Kovalszki, MD, Mary Jo Strobel, Dan Gratie, PharmD, MS, Amy G. Edgecomb, PharmD, MPH, Cara Schmitt, MS, Waseem Ahmed, BSc, MBA, Arijita Deb, PhD

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Optimizing Adherence to Oral Anticancer Agents: Results from an Implementation Mapping Study by Benyam Muluneh, Maurlia Upchurch, Emily Mackler, Ashley Leak Bryant, William A. Wood, Stephanie B. Wheeler, Leah L. Zullig, Jennifer Elston Lafata

“…Clinical trials inform cancer care, yet real-world outcomes often diverge due to patient-related factors, like age, organ dysfunction, and nonadherence to oral anticancer agents (OAAs). …”
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Biomarker discovery for non-invasive diagnosis of inflammatory bowel disease using blood transcriptomics by Mohammad Hossein Derakhshan Nazari, Mahsa Ghorbaninejad, Shabnam Shahrokh, Anna Meyfour

“…LASSO and SVM identified a three-mRNA panel—IL4R, EIF5A, and SLC9A8—which achieved 84% diagnostic accuracy in the discovery cohort and 99% accuracy in the real-life cohort. Network analysis highlighted NDUFB2 as a key downregulated hub gene linked to mitochondrial complex I dysfunction and oxidative phosphorylation disruption. …”
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Knockout of bcas3 gene causes neurodevelopment defects in zebrafish by Huihui Liu, Nianyi Sun, Zhenxing Liu, Jinze Li, Xianqin Zhang

“…Additionally, Acridine Orange staining was employed to evaluate apoptosis. Western blot and real-time RT-PCR were used to analyze the expression levels of genes. …”
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A Novel Preclinical Murine Model of Systemic Lupus Erythematosus–Like Cardiovascular Disease by Marice K. McCrorey, Kennedy P. Hawkins, Marharyta Semenikhina, Matthew Bernstein, Ryan Lacey, C. Alex Colvert, Jim C. Oates, Betty P. Tsao, Kristine Y. DeLeon‐Pennell, Oleg Palygin, Melissa A. Cunningham, Justin P. Van Beusecum

“…At 16 weeks, tissues were harvested, weighed, and analyzed by histology, immunofluorescence, real‐time quantitative polymerase chain reaction, and enzyme‐linked immunosorbent assays. …”
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Gestational high-sucrose diet mediated vascular hyper-contractility in mesenteric arteries from offspring by Xinying Liu, Meng Liu, Chunxia Wang, Liting Duan, Qinggui Ren, Shuli Jiang, Jing Han, Hongwei Fu, Xiao Sun, Dongmei Man, Xueqin Feng

“…The whole-transcriptome sequencing (RNA-seq) of MAs was performed to reveal the different genes and possible pathway. Real-time PCR and western blot were performed to access mRNA and protein expression. …”
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FCMCoach: Personalized Virtual Coaching Based on Fuzzy Cognitive Maps by Georgia Sovatzidi, Dimitris K. Iakovidis

“…The effectiveness of the proposed framework is demonstrated on a dataset representing a population of 200 subjects, created using measurements from a real recreational area in Greece, with several nature trails. …”
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Distinct mechanisms of inadequate erythropoiesis induced by tumor necrosis factor alpha or malarial pigment. by Abigail A Lamikanra, Alison T Merryweather-Clarke, Alex J Tipping, David J Roberts

“…The role of infection in erythropoietic dysfunction is poorly understood. In children with P. falciparum malaria, the by-product of hemoglobin digestion in infected red cells (hemozoin) is associated with the severity of anemia which is independent of circulating levels of the inflammatory cytokine tumor necrosis alpha (TNF-α). …”
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Thromboembolic complications in antiphospholipid syndrome and ankylosing spondylitis (two clinical cases) by K. S. Nurbaeva, F. A. Cheldieva, A. A. Shumilova, A. M. Lila, T. M. Reshetnyak

“…Perhaps the combination of APS and AS is an underestimated problem, and the information available in the literature does not reflect the real numbers. It is obvious that further research is needed to improve the treatment of patients with AS with thrombosis.…”
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Challenges of Diagnosis and Treatment Choice in Riedel‘s Fibrosing Thyroiditis: Clinical Case Examples by M. G. Davydovich, R. V. Ipaeva, K. P. Derevyanko

“…Clinically distinct Riedel’s fibrosing thyroiditis is extremely rare, accounting for only 0.05 % of histologically verified thyroiditis cases, as follows from the real clinical practice and literature. Classic Riedel’s thyroiditis is typified by a marked compression syndrome, which may lack at initial disease stages. …”
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