Transformer-based multimodal precision intervention model for enhancing diaphragm function in elderly patients by Ma Xinli, Zhao Jie, Yan Ming, Zhang Yanping, Li Fan, Jia Jing, Ding Lu

“…To address the deficiency of precise, real-time decision support in this context, a novel artificial intelligence framework is proposed, integrating imaging, physiological signals, and ventilator parameters. …”
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Arterial Stiffness and Subclinical Inflammation in Children with Familial Mediterranean Fever: A Comprehensive Analysis by Nadide Melike Sav, Hasan Baki Altinsoy, Betul Turen, Ayşe Gökçe

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Clinical significance of expression of the marker of adaptation to hypoxia HIF-1α in pregnant women with initial forms of venous disease by E. Iu. Iupatov, L. I. Maltseva, T. P. Zefirova, R. S. Zamaleeva, I. M. Ignatiev, O. A. Kravtsova

“…Expression of the HIF-1á transcription factor at gestational age of 18–20 and 36 weeks was performed by using real-time polymerase chain reaction.Results. Altered functional state of the veins was found in all pregnant women from the main group, which was accompanied by formation of varying degree platelet sludge in the area of the venous valves in the majority of women, as well as signs of endothelial dysfunction and venous hypoxia highlighted with HIF1-á gene expression upregulated by 2.18-fold. …”
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Evaluating the Accuracy of an Artificial Intelligence-Based Application for Diagnosing Temporomandibular Disorders by Haeseong Lee, Salma Awwad, Areeg Elmusrati, Chinmayee Patil, Sang Chung, Anette Vistoso, Amila Adili, Parish Sedghizadeh

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Renal Function and its Time‐Sensitive Influence on Survival Rates of Acute Myocardial Infarction by Hirota Kida, Yuki Matsuoka, Daisuke Sakamoto, Shungo Hikoso, Daisaku Nakatani, Katsuki Okada, Akihiro Sunaga, Taiki Sato, Tetsuhisa Kitamura, Yasuhiko Sakata, Hiroshi Sato, Masatsugu Hori, Issei Komuro, Yohei Sotomi, Yasushi Sakata

“…However, in patients with chronic kidney disease (CKD), the use of contrast media can exacerbate renal dysfunction, often necessitating alternative strategies. …”
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Optimizing Revascularization in Ischemic Cardiomyopathy: Comparative Evidence on the Benefits and Indications of CABG and PCI by Dan M. Prunea, Calin Homorodean, Maria Olinic, Alexandru Achim, Dan-Mircea Olinic

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Rs7903146 variant of TCF7L2 gene and rs18012824 variant of PPARG2 gene (Pro12Ala) are associated with type 2 diabetes mellitus in Novosibirsk population by Irina Arkad'evna Bondar', Maksim Leonidovich Filipenko, Olesya Yur'evna Shabel'nikova, Ekaterina Alexandrovna Sokolova

“…Combined beta-cell dysfunction and insulin resistance genotypes were identified in 56% of tested subjects, isolated insulin resistance ? …”
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Co-regulation and synteny of GFM2 and NSA2 links ribosomal function in mitochondria and the cytosol with chronic kidney disease by Minjie Zhang, Christer Hogstrand, Paola Pontrelli, Afshan N Malik

“…In the current paper, we show that NSA2 expression is co-regulated with the GTP-dependent ribosome recycling factor mitochondrial 2 (GFM2) and provide a molecular link between cytosolic and mitochondrial ribosomal biogenesis with mitochondrial dysfunction in chronic kidney disease (CKD). Methods Human renal tubular cells (HK-2) were cultured (+/- zinc, or 5mM/20mM glucose). mRNA levels were quantified using real-time qPCR. …”
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Dynamic URP: Revisiting Urethral Retro-Resistance Pressure for Contemporary Sphincter-Targeted Therapy by Nicole Fleischmann

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Sexual dysfunction and other prolactin-related side effects of antipsychotic drugs in schizophrenia: Protocol for a systematic review with single-arm, pairwise, and network meta-an... by Wulf Peter Hansen, Spyridon Siafis, Orestis Efthimiou, Shimeng Dong, Johannes Schneider-Thoma, Stefan Leucht, Karl Heinz Möhrmann, Elfriede Scheuring

“…Introduction Sexual dysfunctions are common yet underreported side effects of antipsychotics for schizophrenia, affecting 30-80% of treated individuals. …”
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Sexual dysfunction and other prolactin-related side effects of antipsychotic drugs in schizophrenia: Protocol for a systematic review with single-arm, pairwise, and network meta-an... by Wulf Peter Hansen, Spyridon Siafis, Orestis Efthimiou, Shimeng Dong, Johannes Schneider-Thoma, David D. Kim, Stefan Leucht, Karl Heinz Möhrmann, Elfriede Scheuring

“…Introduction Sexual dysfunctions are common yet underreported side effects of antipsychotics for schizophrenia, affecting 30-80% of treated individuals. …”
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Formation of reactive species via high power microwave induced DNA damage and promoted intrinsic pathway-mediated apoptosis in lung cancer cells: An in vitro investigation by Juie Nahushkumar Rana, Sohail Mumtaz, Ihn Han, Eun Ha Choi

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Antithrombotic Therapy after Bleeding in Elderly Polimorbid Patient: Our Time Challenge by M. R. Atabegashvili, M. Yu. Gilyarov, E. V. Konstantinova, A. N. Kostina, A. P. Nesterov, T. D. Pakharkova, A. E. Udovichenko

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Evaluation of the protective role of resveratrol on LPS-induced septic intestinal barrier function via TLR4/MyD88/NF-κB signaling pathways by Zhongliang Shi, Yanna Jiao, Zhizhen Lai, Juan Liu, Bo Yang, Mahong Hu, Jianbiao Meng

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Hu-lu-su-pian ameliorates hepatic steatosis by regulating CIDEA expression in AKT-driven MASLD mice by Rumeng Ren, Rumeng Ren, Qi Wang, Qi Wang, Dongjie Deng, Dongjie Deng, Aoao Guo, Aoao Guo, Xin Chen, Xin Chen, Yan Meng, Yan Meng, Ying Fang, Ying Fang, Guohua Zheng, Guohua Zheng, Zhong Xu, Zhong Xu, Man Li, Junjie Hu, Junjie Hu

“…However, the molecular mechanism by which HLSP affects metabolic dysfunction-associated steatotic liver disease (MASLD) remains unclear. …”
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Focused radiofrequency treatment of postpartum vaginal relaxation syndrome by Yu. E. Dobrokhotova, T. S.K. Nagieva, E. N. Kareva

“…Assessment of the collagenogenesis and neoangiogenesis was carried out base on measuring expression level of the mRNA specific to proteins of the vaginal connective tissue by using real-time polymerase chain reaction.Results. Our study allowed to find that anatomical and functional state of the vulvovaginal area and perineum were significantly improved as well as relief of PFD symptoms. …”
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Clinical and functional state of the retina after adequately performed laser coagulation of peripheral vitreochorioretinal dystrophies by V. V. Neroev, G. Yu. Zakharova, T. D. Okhotsimskaya, I. V. Tsapenko, M. V. Zueva, M. A. Arakelyan, B. M. Magamadov

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Integrated profiling of adiponectin and cytokine signaling pathways in high-fat diet-induced MASLD reveals early markers of disease progression by Rabia Johnson, Samukelisiwe Shabalala, Lawrence Mabasa, Liske Kotzé-Hörstmann, Nonhlakanipho Sangweni, Pritika Ramharack, Jyoti Sharma, Carmen Pheiffer, Afolake Arowolo, Hanél Sadie-Van Gijsen

“…Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD), which affects a significant portion of the global population, is linked to high-fat diets (HFD) and characterized by abnormal lipid accumulation and activation of inflammatory pathways in hepatocytes. …”
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MicroRNA-669f-5p targeting deoxycytidinephosphate deaminase contributes to sevoflurane-induced cognitive impairments in aged mice via the TLR2/4–MyD88–NF-κB pathway by Yuanping Zhong, Chao Zhang, Yuan Li, Dongqin Chen, Chunchun Tang, Xue Zheng, Zhaoqiong Zhu

“…Background: Postoperative cognitive dysfunction (POCD) is a common complication associated with sevoflurane anaesthesia in the aged population. …”
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Causes of ocular surface tissue lesions in patients with pseudoexfoliation syndrome by V. V. Potemkin, E. V. Ageeva

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