Genomic and Computational Analysis of Novel SNPs in TNP1 Gene Promoter Region of Bos indicus Breeding Bulls by Kashif Hameed Anjum, Asif Nadeem, Maryam Javed, Hafiz Ishfaq Ahmad, Amjad Riaz, Wasim Shehzad, Jahanzaib Azhar, Muhammad Fahad Bhutta

“…Modern computational tools were used to predict putative transcription factor binding in the TNP1 promoter and CpG islands in the TNP1 promoter region. …”
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Generation of a genetically double-attenuated Plasmodium berghei parasite that fully arrests growth during late liver stage development. by Melanie Schmid, Raphael Beyeler, Reto Caldelari, Ruth Rehmann, Volker Heussler, Magali Roques

“…Through a comprehensive phenotyping screen, we identified the hscb gene, encoding a putative iron-sulfur protein assembly chaperone, as crucial for liver stage development, making it a suitable candidate gene for GAP generation. …”
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Pathogenic Process-Associated Transcriptome Analysis of Stemphylium lycopersici from Tomato by Dezhen Zhang, Wenjuan Chi, Cuicui Wang, Huijie Dai, Jintang Li, Chunlei Li, Fajun Li

“…Overall, we present some putative key genes and processes that may be crucial for S. lycopersici pathogenesis. …”
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Whole exome sequencing identifies ABHD14A and MRNIP as novel candidate genes for developmental language disorder by Amal Bouzid, Malek Belcadhi, Amal Souissi, Meryam Chelly, Fakher Frikha, Hela Gargouri, Crystel Bonnet, Fida Jebali, Salma Loukil, Christine Petit, Saber Masmoudi, Rifat Hamoudi, Mariem Ben Said

“…These results suggest ABHD14A and MRNIP, as putative candidate genes for DLD susceptibility. Our findings reveal the involvement of novel candidate genes in the genetic etiology of DLD and explore the potential future utility of WES in the diagnosis of such complex disorders.…”
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A High-Quality Phased Genome Assembly of Stinging Nettle (<i>Urtica dioica</i> ssp. <i>dioica</i>) by Kaede Hirabayashi, Christopher R. Dumigan, Matúš Kučka, Diana M. Percy, Gea Guerriero, Quentin Cronk, Michael K. Deyholos, Marco Todesco

“…We annotated 20,333 and 20,140 genes for each haplotype, covering over 90% of the complete BUSCO genes and including two copies of a gene putatively encoding the neurotoxic peptide urthionin, which could contribute to nettle’s characteristic sting. …”
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X-Linked Adrenal Hypoplasia Congenita in a Boy due to a Novel Deletion of the Entire NR0B1 (DAX1) and MAGEB1–4 Genes by Aleksandra Rojek, Maciej R. Krawczynski, Aleksander Jamsheer, Anna Sowinska-Seidler, Barbara Iwaniszewska, Ewa Malunowicz, Marek Niedziela

“…Array CGH was used to confirm the putative copy-number variation of NR0B1 (DAX1) revealing a novel hemizygous deletion encompassing the entire NR0B1 (DAX1) gene together with the MAGEB genes. …”
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KELIMPAHAN JENIS FITOPLANKTON DI INLET DAN OUTLET WADUK BENING SEBAGAI BAHAN PENYUSUN MEDIA PEMBELAJARAN BERBENTUK POSTER by Andhi Bayu Priambodo

“…Phytoplankton abundance in the inlet area of the Month December to February respectively is 330 ind/l, 286.291 ind/l, and 258.892 ind/l, while the abundance of phytoplankton in the area of the outlet of the Month December to February respectively Tutut 130.844 ind/l, 112.200 ind/l, and 98.430 ind/l. …”
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The Association between KIF6 Single Nucleotide Polymorphism rs20455 and Serum Lipids in Filipino-American Women by Irma B. Ancheta, Cynthia A. Battie, Dan Richard, Christine V. Ancheta, Nancy Borja-Hart, Annabelle S. Volgman, Yvette Conley

“…The Trp719Arg allele of KIF6 rs20455, a putative risk factor for CHD especially in those with elevated low-density lipoprotein cholesterol (LDL-C), was investigated in Filipino-American women (FAW, n=235) participating in health screenings in four cities. …”
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Alzheimer’s Disease and <i>Porphyromonas gingivalis</i>: Exploring the Links by Ivana Shawkatova, Vladimira Durmanova, Juraj Javor

“…<i>P. gingivalis</i>, a major driver of periodontitis, is recognized for its potential systemic effects and its putative role in AD pathogenesis. This review examines evidence connecting <i>P. gingivalis</i> to hallmark AD features, such as amyloid β accumulation, tau hyperphosphorylation, neuroinflammation, and other neuropathological features consistent with AD. …”
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COEXISTENCE OF MULTIPLE GENE VARIANTS IN SOME PATIENTS WITH ERYTHROCYTOSES by Andrea Benetti, Irene Bertozzi, PhD, MD, Giulio Ceolotto, Irene Cortella, Daniela Regazzo, Giacomo Biagetti, Elisabetta Cosi, Maria Luigia Randi, MD, Prof

“…In 23 patients (19.45%), more than 1 putative variant was found in multiple genes. Conclusions: Genetic variants in patients with erythrocytosis were detected in about 2/3 of our cohort. …”
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Paracetamol metabolism by endothelial cells – Potential mechanism underlying intravenous paracetamol-induced hypotension by Johs Dannesboe, Joakim A. Bastrup, Kathrine Holm Nielsen, Pelle Munck, Morten B. Thomsen, Clare L. Hawkins, Thomas A. Jepps

“…Taken together, these data provide a putative mechanism to explain the presentation of hypotension in critically ill patients following IV APAP administration.…”
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Fas Ligand DNA Enhances a Vaccination Effect by Coadministered DNA Encoding a Tumor Antigen through Augmenting Production of Antibody against the Tumor Antigen by Boya Zhong, Guangyu Ma, Ayako Sato, Osamu Shimozato, Hongdan Liu, Quanhai Li, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa

“…We examined whether administration of DNA encoding FasL gene enhanced antitumor effects in mice that were vaccinated with DNA expressing a putative tumor antigen gene, β-galactosidase (β-gal). …”
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SIV infection induces alterations in gene expression and loss of interneurons in Rhesus Macaque frontal cortex during early systemic infection by Richard C. Crist, Samar N. Chehimi, Saurabh S. Divakaran, Michael J. Montague, Sébastien Tremblay, Noah Snyder-Mackler, Martin O. Bohlen, Kenneth L. Chiou, Trish M. Zintel, Cayo Biobank Research Unit, Michael L. Platt, Halvor Juul, Guido Silvestri, Matthew R. Hayes, Dennis L. Kolson, Benjamin C. Reiner

“…In total, these results identify cell type-specific molecular mechanisms putatively capable of underlying long-term neurocognitive alterations in persons living with HIV.…”
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Towards a New Taxonomy of Pattern-Making in the Visuo-Spatial Domain in Early Childhood Based on Zygonic Theory and the Sounds of Intent Framework of Musical Development by Adam Ockelford, Sarah McCarthy, Sue Gifford, Helen Thouless, Sharon Kirk, Michael Thorpe

“…An algorithm is used to demonstrate the structural processing load for different pattern types, which allows the putative developmental stages of pattern-processing capacity to be plotted sequentially. …”
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Replay of incidentally encoded novel odors in the rat by Cassandra L. Sheridan, Lauren Bonner, Jonathon D. Crystal

“…We conclude that rats encode multiple pieces of putatively unimportant information, and later replayed a stream of novel episodic memories when that information was needed to solve an unexpected problem.…”
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Evaluation of allergenic protein profiles in three Chinese high-oleic acid peanut cultivars using NanoLC-Orbitrap mass spectrometry by Xinke Yang, Haochen Bai, Lijun Yin, Jin Wang, Wentong Xue, Xin Jia

“…For this purpose, an Orbitrap Fusion mass spectrometry (MS)-based method that is feasible for identification of putative allergenic protein as well as semi-quantitation of five major allergen protein in three different Chinese high-oleic peanut cultivars (JH 13, JH 16 and JH 18) have been reported. …”
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The Quantitative Analysis of bFGF and VEGF by ELISA in Human Meningiomas by Yves Denizot, Rafael De Armas, François Caire, Jean Jacques Moreau, Isabelle Pommepuy, Véronique Truffinet, François Labrousse

“…The ELISA procedure is, thus, an interesting tool to ensure VEGF and bFGF levels in meningiomas and to test putative correlations with clinical parameters. It is, thus, tempting to speculate that ELISA would also be valuable for the quantitative analysis of other angiogenic growth factors and cytokines in intracranial tumours.…”
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Probiogenomic analysis of Limosilactobacillus fermentum SD7, a probiotic candidate with remarkable aggregation abilities by Thunchanok Yaikhan, Monwadee Wonglapsuwan, Nuntiya Pahumunto, Natakorn Nokchan, Rawee Teanpaisan, Komwit Surachat

“…In addition, L. fermentum SD7 genome contains four strain-specific putative CRISPR-associated genes and lacks antimicrobial resistance and virulence genes. …”
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ATP Citrate Lyase <i>ClACLB-1</i> Facilitates Citrate Cleavage in Lemon by Chuang Lu, Wenhui Yang, Huaxi Zhang, Yanrong Wu, Huina Meng, Lifeng Lv, Wanping Lu, Dongmei Zhao, Guixiang Huang

“…In this study, a key candidate gene, <i>ClACLB-1</i>, for citrate cleavage was identified from the genome data of ‘Xiangshui’ lemon [<i>Citrus limon</i> (L.) Burm f.]. The putative protein coded by the gene <i>ClACLB</i>-1 is localized in the nuclear and cell membranes. …”
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Medical Students’ Acceptance of Tailored e–Mental Health Apps to Foster Their Mental Health: Cross-Sectional Study by Catharina Grüneberg, Alexander Bäuerle, Sophia Karunakaran, Dogus Darici, Nora Dörrie, Martin Teufel, Sven Benson, Anita Robitzsch

“…The Unified Theory of Acceptance and Use of Technology (UTAUT) was applied. Differences in acceptance were examined and a multiple hierarchical regression analysis was conducted. …”
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