Development of a high-throughput screening system for identification of novel reagents regulating DNA damage in human dermal fibroblasts by Bae Seunghee, An In-Sook, An Sungkwan

“…In the present study, we developed a novel DNA repair regulating material discovery (DREAM) system for the high-throughput screening and identification of putative materials regulating DNA repair in skin cells. …”
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Whole-genome sequencing and secondary metabolite exploration of the novel Bacillus velezensis BN with broad-spectrum antagonistic activity against fungal plant pathogens by Yanli Zheng, Tongshu Liu, Ziyu Wang, Xu Wang, Haiyan Wang, Ying Li, Wangshan Zheng, Shiyu Wei, Yan Leng, Jiajia Li, Yan Yang, Yang Liu, Zhaoyu Li, Qiang Wang, Qiang Wang, Yongqiang Tian

“…Genomic analysis revealed that 29% of the genes are directly involved in plant growth, while 70% of the genes are indirectly involved. In addition, 12 putative biosynthetic gene clusters were identified, responsible for the synthesis of secondary metabolites, such as non-ribosomal peptides, lanthipeptides, polyketides, siderophores, and terpenes. …”
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Mediators of Inflammation and Their Effect on Resident Renal Cells: Implications in Lupus Nephritis by Susan Yung, Kwok Fan Cheung, Qing Zhang, Tak Mao Chan

“…In this review, we provide an overview of the synthesis and putative roles of IL-6, TNF-α, IFN-α, and hyaluronan in the pathogenesis of lupus nephritis focusing on their effects on human mesangial cells and proximal renal tubular epithelial cells.…”
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Could LC-NE-Dependent Adjustment of Neural Gain Drive Functional Brain Network Reorganization? by Carole Guedj, David Meunier, Martine Meunier, Fadila Hadj-Bouziane

“…Thus, our proposal offers a unified framework integrating the putative influence of the LC-NE system on both local- and long-range adjustments of brain dynamics underlying behavioral flexibility.…”
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A Quantitative Trait Locus on Chromosome 5p Influences D-Dimer Levels in the San Antonio Family Heart Study by V. P. Diego, L. Almasy, D. L. Rainwater, M. C. Mahaney, A. G. Comuzzie, S. A. Cole, R. P. Tracy, M. P. Stern, J. W. MacCluer, J. Blangero

“…To our knowledge, the putative QTL on chromosome 5p is novel. The possible QTL on chromosome 2q is discussed in relation to a recent report of linkage of a related hemostatic factor to the same location. …”
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Genetic Vectors as a Tool in Association Studies: Definitions and Application for Study of Rheumatoid Arthritis by Igor Sandalov, Leonid Padyukov

“…To identify putative relations between different genetic factors in the human genome in the development of common complex disease, we mapped the genetic data to an ensemble of spin chains and analysed the data as a quantum system. …”
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Caused motion events in Modern Uyghur: a typological perspective by Tusun Alimujiang, Hendriks Henriëtte

“…Detailed comparisons with French and Turkish (putatively verb-framed) reveal intra-typological variations in that Uyghur speakers systematically used verb-framed constructions while French and Turkish speakers exhibit much flexibility and a general preference for satellite-framed constructions. …”
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A decision‐making tool for navigating extracellular vesicle research and product development by Francesca Loria, Sabrina Picciotto, Giorgia Adamo, Andrea Zendrini, Samuele Raccosta, Mauro Manno, Paolo Bergese, Giovanna L. Liguori, Antonella Bongiovanni, Nataša Zarovni

“…This translates into a multitude of choices and putative solutions that any EV researcher must confront in both research and translational environments. …”
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The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A “Me Too” or “the Special One” Antidiabetic Class? by Ricardo Godinho, Cristina Mega, Edite Teixeira-de-Lemos, Eugénia Carvalho, Frederico Teixeira, Rosa Fernandes, Flávio Reis

“…Recent studies have been focusing on the putative ability of DPP-4 inhibitors to preserve pancreas function, in particular due to the inhibition of apoptotic pathways and stimulation of β cell proliferation. …”
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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM. by Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory A Cary, Gregory W Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, Emory-Sage-SGC TREAT-AD Center, Alison D Axtman

“…RNA sequencing and genetic data support spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) as putative targets to be modulated for Alzheimer's disease (AD) therapy. …”
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Investigating the Relationship between Transverse Relaxation Rate () and Interecho Time in MagA-Expressing, Iron-Labeled Cells by Casey Y. Lee, R. Terry Thompson, Frank S. Prato, Donna E. Goldhawk, Neil Gelman

“…This report investigates 9.4 T nuclear magnetic resonance properties of mammalian cells overexpressing MagA, a putative iron transport protein from magnetotactic bacteria. …”
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Minimal Impacts of Tyre Particle Exposure on Estuarine Meiofaunal Community Structure, Primary Production, and Nutrient Cycling by Charlotte Woodhouse, Dannielle Senga Green, Andy Foggo, Paul J. Somerfield, Richard C. Thompson, Samantha L. Garrard

“…An increase in Tanaidacea was observed in 1% and 5% tyre particle treatments, putatively due to reduced macrofaunal predation. Previous studies have highlighted the ecotoxicity of tyre wear particles. …”
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Identification and Expression Analysis of Sugar Transporter Gene Family in Aspergillus oryzae by Gongbo Lv, Chunmiao Jiang, Tiantian Liang, Yayi Tu, Xiaojie Cheng, Bin Zeng, Bin He

“…Based on the conserved protein domain search, 127 putative SUT genes were identified in A. oryzae and further categorized into eight distinct subfamilies. …”
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Thyroid Autoimmunity in the Context of Type 2 Diabetes Mellitus: Implications for Vitamin D by Konstantinos Toulis, Xanthippi Tsekmekidou, Evangelos Potolidis, Triantafyllos Didangelos, Anna Gotzamani-Psarrakou, Pantelis Zebekakis, Michael Daniilidis, John Yovos, Kalliopi Kotsa

“…Thus, we aimed to explore the putative association between T2DM and thyroid autoimmunity (TAI) focusing on the role of 25-hydroxy-vitamin D (25(OH)D). …”
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Patterns of Isoform Variation for N Gene Subgenomic mRNAs in Betacoronavirus Transcriptomes by James J. Kelley, Andrey Grigoriev

“…In SARS-CoV, they restore the reading frame for a putative TIS (also a CTG codon) in the same relative position as in SARS-CoV-2. …”
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A novel p.127Val>Ile single nucleotide polymorphism in the gene and its relation to litter size in Thin-tailed Indonesian ewes by Mutasem Abuzahra, Mohammed Baqur S. Al-Shuhaib, Dwi Wijayanti, Mustofa Helmi Effendi, Imam Mustofa, Ikechukwu Benjamin Moses

“…Conclusion In conclusion, the results of our study suggest that rs1087815963 has a remarkable negative impact on the MTNR1A with a putative alteration in the binding with melatonin. …”
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The Chloroplastic Small Heat Shock Protein Gene KvHSP26 Is Induced by Various Abiotic Stresses in Kosteletzkya virginica by Xiaohua Liu, Lizi Zhao, Jianzhao Li, Lijun Duan, Kai Zhang, Xuqiang Qiao, Weihuan Li, Chengchao Zheng, Xiaoli Tang, Hongxia Zhang

“…However, their possible roles in halophyte plants are still largely known. In this work, a putative sHSP gene KvHSP26 was cloned from K. virginica. …”
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The impact of Ca2+ on the protective mechanisms of the photosystem under drought stress by Yanli Wei, Tongen Zhang, Tongtong Yao, Zihan Wang, Yanhui Che, Huihui Zhang

“…Upon application of external calcium under drought conditions, leaf wilting was reduced, chlorophyll content increased, Fv/Fm, PIabs, and PItotal improved, fluorescence intensities at the K and L points as well as Y(NPQ) decreased, cyclic electron transport and Pn were enhanced, stomatal aperture increased, and ΔI/Io improved. …”
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Neonatal 5,7-DHT Lesions Cause Sex-Specific Changes in Mouse Cortical Morphogenesis by Christine F. Hohmann, Celena Richardson, Ella Pitts, Joanne Berger-Sweeney

“…Both monoaminergic and cholinergic afferent projections to the neocortex putatively modulate cortical morphogenesis and plasticity. …”
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Profiling Proteins in the Hypothalamus and Hippocampus of a Rat Model of Premenstrual Syndrome Irritability by Mingqi Qiao, Peng Sun, Yang Wang, Sheng Wei, Xia Wei, Chunhong Song, Fushun Wang, Jibiao Wu

“…Baixiangdan, a traditional Chinese medicine effective against PMS irritability, was used in the rat model to study putative target proteins of this medicine. The hypothalamus and hippocampus of each group modelling PMS displayed the following features: decreased expression of Ulip2, tubulin beta chain 15, α actin, and interleukin 1 receptor accessory protein; increased expression of kappa-B motif-binding phosphoprotein; decreased expression of hydrolase at the end of ubiquitin carboxy, albumin, and aldolase protein; and increased expression of M2 pyruvate kinase, panthenol-cytochrome C reductase core protein I, and calcium-binding protein. …”
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