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The Pollyanna Effect: The role of positive personal and group identity defense mechanisms
Published 2025-01-01“…The assumption that the contribution of group identity to the Pollyanna effect increases in crises associated with the experience of hard-to-control threat and collective trauma is stated. …”
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Generation and characterization of the LINC01405 knockout human embryonic stem cell line
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Social determinants of student mental health before and after the Beirut port explosion: two cross-sectional studies
Published 2025-01-01“…Abstract Background Students in Lebanon are facing the devastating impact of multiple national crises, including an unprecedented economic collapse and the Beirut port explosion that killed hundreds, injured thousands, and displaced hundreds of thousands of people. …”
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DLK-dependent axonal mitochondrial fission drives degeneration after axotomy
Published 2024-12-01“…Importantly, we show that CRISPR mediated Drp1 depletion protects mouse retinal ganglion neurons from degeneration after optic nerve crush. …”
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Geranylgeranyl Transferase-I Knockout Inhibits Oxidative Injury of Vascular Smooth Muscle Cells and Attenuates Diabetes-Accelerated Atherosclerosis
Published 2020-01-01“…In this study, mouse conditional knockout of VSMC GGTase-I (Pggt1bΔ/Δ mice) was generated using the CRISPR/Cas9 system. The mouse model of diabetes-accelerated atherosclerosis was induced by streptozotocin injections and an atherogenic diet. …”
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Comparative analysis of state-level policy responses in global health governance: A scoping review using COVID-19 as a case.
Published 2024-01-01“…Using COVID-19 as an example, this study aims to compare the policies and measures implemented by different states during the COVID-19 pandemic and to synthesize experiences to strengthen global health governance for future infectious disease crises.<h4>Methods</h4>We used Arksey and O'Malley's five-stage scoping review framework and PRISMA methodology was used for literature search and decision on relevant studies. …”
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Russian population’s political activities in the first third of the XX century on the example of the Peasant Union creation movement
Published 2023-12-01“…Contradictory nature of Bolshevik policy, the concept of “interlocking” between city and countryside, growing “emergency” and crises of the new economic policy against the background of granting peasants relative economic freedom led to peasant demands growth for protecting their economic rights and creating organizations that resembled trade unions in city. …”
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Loss of Myh14 Increases Susceptibility to Noise-Induced Hearing Loss in CBA/CaJ Mice
Published 2016-01-01“…In the present study, we used CRISPR/Cas9 technology to establish a Myh14 knockout mice line in CBA/CaJ background (now referred to as Myh14−/− mice) and clarify the role of MYH14 in the cochlea and NIHL. …”
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Analytical hierarchy process as a tool supporting a decision-making for assessment of the risk of transboundary infectious animal disease introduction to the Russian Federation an...
Published 2023-03-01“…The demand for food steadily increases during crises, which in turn increases the role of the veterinary service, whose tasks include protecting the country’s territory from the introduction of infectious diseases of animals from foreign countries; implementation of measures to prevent and eliminate infectious and other diseases in agricultural, domestic, zoo and other animals, fur-bearing animals, birds, fish and bees, as well as the implementation of plans of the regional veterinary service in the field of animal husbandry. …”
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Personnel training for the security and defense sector as a prerequisite for ensuring the national security of Ukraine
Published 2021-09-01“…It has been established that one of the necessary steps in the direction of ensuring national security and citizens’ protection of rights and freedoms is strengthening the institutional, defense and security capabilities of bodies belonging to the security and defense sector. …”
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BRCA1 is involved in sustaining rapid antler growth possibly via balancing of the p53/endoplasmic reticulum stress signaling pathway
Published 2025-01-01“…Among these 39 genes, the tumor suppressor gene, BRCA1, was found to be more sensitive to DNA damage in the AnSCs compared to that in the deer somatic cells, and BRCA1 deletion in the AnSCs via CRISPR/Cas9 resulted in significantly higher levels of DNA damage. …”
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Presenting the Model of Eco-Leadership in Elementary Schools with an Interpretive Phenomenological Approach
Published 2024-10-01“…Introduction: Nowadays, environmental protection and conservation have become a critical issue worldwide. …”
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Development of ptxD/Phi as a new dominant selection system for genetic manipulation in Cryptococcus neoformans
Published 2025-01-01“…A codon-optimized ptxD gene from Pseudomonas stutzeri was cloned under the TEF promoter. Using the transient CRISPR-Cas9 coupled with electroporation system, we integrated the ptxD gene into the C. neoformans genome and assessed the impact of ptxD integration on cell growth and virulence factors. …”
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Transcriptional profiles of Microcystis reveal gene expression shifts that promote bloom persistence in in situ mesocosms
Published 2025-01-01“…These capacities coincided with the upregulation of toxin-antitoxin systems, CRISPR-cas genes, and transposases suggesting that phage defense and genome rearrangement are critical in bloom persistence. …”
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One health agriculture: Heat stress mitigation dilemma in agriculture
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Genetic and pharmacological targeting of HINT2 promotes OXPHOS to alleviate inflammatory responses and cell necrosis in acute pancreatitis
Published 2025-02-01“…Furthermore, CRISPR/Cas9-mediated HINT2 knockout significantly impaired the protective effects of Emo against AP-induced mitochondrial energy metabolism disorders, inflammatory responses, and acinar cell necrosis. …”
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MUC2 expression modulates immune infiltration in colorectal cancer
Published 2025-01-01“…By employing CRISPR-mediated MUC2 knockout, we investigated the influence of MUC2 on tumor immune infiltration and its interplay with T cells and NK cells enriched peripheral blood mononuclear cells (PBMCs) in 3D spheroid cultures.ResultsWhile MUC2 was more abundant in LS-174T cell line compared to HT-29, its knockout resulted in increased immune infiltration solely in the HT-29 cell line, but not in the LS-174T cell line. …”
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