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  1. 101

    The Pollyanna Effect: The role of positive personal and group identity defense mechanisms by T.A. Nestik

    Published 2025-01-01
    “…The assumption that the contribution of group identity to the Pollyanna effect increases in crises associated with the experience of hard-to-control threat and collective trauma is stated. …”
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  2. 102
  3. 103

    Social determinants of student mental health before and after the Beirut port explosion: two cross-sectional studies by Julia Scheuring, Tania Bosqui

    Published 2025-01-01
    “…Abstract Background Students in Lebanon are facing the devastating impact of multiple national crises, including an unprecedented economic collapse and the Beirut port explosion that killed hundreds, injured thousands, and displaced hundreds of thousands of people. …”
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  4. 104

    DLK-dependent axonal mitochondrial fission drives degeneration after axotomy by Jorge Gómez-Deza, Matthew Nebiyou, Mor R. Alkaslasi, Francisco M. Nadal-Nicolás, Preethi Somasundaram, Anastasia L. Slavutsky, Wei Li, Michael E. Ward, Trent A. Watkins, Claire E. Le Pichon

    Published 2024-12-01
    “…Importantly, we show that CRISPR mediated Drp1 depletion protects mouse retinal ganglion neurons from degeneration after optic nerve crush. …”
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  5. 105

    Geranylgeranyl Transferase-I Knockout Inhibits Oxidative Injury of Vascular Smooth Muscle Cells and Attenuates Diabetes-Accelerated Atherosclerosis by Guo-Ping Chen, Jian Yang, Guo-Feng Qian, Wei-Wei Xu, Xiao-Qin Zhang

    Published 2020-01-01
    “…In this study, mouse conditional knockout of VSMC GGTase-I (Pggt1bΔ/Δ mice) was generated using the CRISPR/Cas9 system. The mouse model of diabetes-accelerated atherosclerosis was induced by streptozotocin injections and an atherogenic diet. …”
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  6. 106

    Comparative analysis of state-level policy responses in global health governance: A scoping review using COVID-19 as a case. by Fengyuan Tang, Wenqianzi Yang, Weijia Wu, Yewen Yao, Yi Yang, Qiyi Zheng, Baheti Maireyi, Shengxuan Jin, Hengjin Dong

    Published 2024-01-01
    “…Using COVID-19 as an example, this study aims to compare the policies and measures implemented by different states during the COVID-19 pandemic and to synthesize experiences to strengthen global health governance for future infectious disease crises.<h4>Methods</h4>We used Arksey and O'Malley's five-stage scoping review framework and PRISMA methodology was used for literature search and decision on relevant studies. …”
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  7. 107
  8. 108

    Russian population’s political activities in the first third of the XX century on the example of the Peasant Union creation movement by G. S. Chuwardin, V. G. Ivanov, O. A. Nesterchuk, V. F. Nitsevich, O. A. Sudorgin

    Published 2023-12-01
    “…Contradictory nature of Bolshevik policy, the concept of “interlocking” between city and countryside, growing “emergency” and crises of the new economic policy against the background of granting peasants relative economic freedom led to peasant demands growth for protecting their economic rights and creating organizations that resembled trade unions in city. …”
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  9. 109

    Loss of Myh14 Increases Susceptibility to Noise-Induced Hearing Loss in CBA/CaJ Mice by Xiaolong Fu, Linqing Zhang, Yecheng Jin, Xiaoyang Sun, Aizhen Zhang, Zongzhuang Wen, Yichen Zhou, Ming Xia, Jiangang Gao

    Published 2016-01-01
    “…In the present study, we used CRISPR/Cas9 technology to establish a Myh14 knockout mice line in CBA/CaJ background (now referred to as Myh14−/− mice) and clarify the role of MYH14 in the cochlea and NIHL. …”
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  10. 110

    Analytical hierarchy process as a tool supporting a decision-making for assessment of the risk of transboundary infectious animal disease introduction to the Russian Federation an... by N. V. Lebedev, A. S. Igolkin, K. N. Gruzdev, D. G. Spirin, M. A. Farukh, N. V. Ermilov, G. G. Eremin

    Published 2023-03-01
    “…The demand for food steadily increases during crises, which in turn increases the role of the veterinary service, whose tasks include protecting the country’s territory from the introduction of infectious diseases of animals from foreign countries; implementation of measures to prevent and eliminate infectious and other diseases in agricultural, domestic, zoo and other animals, fur-bearing animals, birds, fish and bees, as well as the implementation of plans of the regional veterinary service in the field of animal husbandry. …”
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  11. 111

    Personnel training for the security and defense sector as a prerequisite for ensuring the national security of Ukraine by V. V. Sokurenko

    Published 2021-09-01
    “…It has been established that one of the necessary steps in the direction of ensuring national security and citizens’ protection of rights and freedoms is strengthening the institutional, defense and security capabilities of bodies belonging to the security and defense sector. …”
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  12. 112
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  14. 114

    BRCA1 is involved in sustaining rapid antler growth possibly via balancing of the p53/endoplasmic reticulum stress signaling pathway by Qianqian Guo, Zhen Wang, Jiping Li, Chao Ma, Junjun Zheng, Hengxing Ba, Guokun Zhang, Chunyi Li

    Published 2025-01-01
    “…Among these 39 genes, the tumor suppressor gene, BRCA1, was found to be more sensitive to DNA damage in the AnSCs compared to that in the deer somatic cells, and BRCA1 deletion in the AnSCs via CRISPR/Cas9 resulted in significantly higher levels of DNA damage. …”
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  15. 115

    Presenting the Model of Eco-Leadership in Elementary Schools with an Interpretive Phenomenological Approach by Adel Zahed babolan, Seyyedmohammad Seyyedkalan

    Published 2024-10-01
    “…Introduction: Nowadays, environmental protection and conservation have become a critical issue worldwide. …”
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  16. 116

    Development of ptxD/Phi as a new dominant selection system for genetic manipulation in Cryptococcus neoformans by Muthita Khongthongdam, Tanaporn Phetruen, Sittinan Chanarat

    Published 2025-01-01
    “…A codon-optimized ptxD gene from Pseudomonas stutzeri was cloned under the TEF promoter. Using the transient CRISPR-Cas9 coupled with electroporation system, we integrated the ptxD gene into the C. neoformans genome and assessed the impact of ptxD integration on cell growth and virulence factors. …”
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  17. 117

    Transcriptional profiles of Microcystis reveal gene expression shifts that promote bloom persistence in in situ mesocosms by Lauren E. Krausfeldt, Paisley S. Samuel, Robert P. Smith, Hidetoshi Urakawa, Barry H. Rosen, Rita R. Colwell, Jose V. Lopez

    Published 2025-01-01
    “…These capacities coincided with the upregulation of toxin-antitoxin systems, CRISPR-cas genes, and transposases suggesting that phage defense and genome rearrangement are critical in bloom persistence. …”
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  18. 118
  19. 119

    Genetic and pharmacological targeting of HINT2 promotes OXPHOS to alleviate inflammatory responses and cell necrosis in acute pancreatitis by Jiaqi Yao, Yuhong Jiang, Pengcheng Zhang, Yifan Miao, Xiajia Wu, Hang Lei, Zhijun Xie, Yong Tian, Xianlin Zhao, Juan Li, Lv Zhu, Meihua Wan, Wenfu Tang

    Published 2025-02-01
    “…Furthermore, CRISPR/Cas9-mediated HINT2 knockout significantly impaired the protective effects of Emo against AP-induced mitochondrial energy metabolism disorders, inflammatory responses, and acinar cell necrosis. …”
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  20. 120

    MUC2 expression modulates immune infiltration in colorectal cancer by Christophe M. Raynaud, Ayesha Jabeen, Eiman I. Ahmed, Eiman I. Ahmed, Satanay Hubrack, Apryl Sanchez, Shimaa Sherif, Ahmad A. Al-Shaibi, Bernice Lo, Bernice Lo, Jessica Roelands, Davide Bedognetti, Davide Bedognetti, Wouter Hendrickx, Wouter Hendrickx

    Published 2025-01-01
    “…By employing CRISPR-mediated MUC2 knockout, we investigated the influence of MUC2 on tumor immune infiltration and its interplay with T cells and NK cells enriched peripheral blood mononuclear cells (PBMCs) in 3D spheroid cultures.ResultsWhile MUC2 was more abundant in LS-174T cell line compared to HT-29, its knockout resulted in increased immune infiltration solely in the HT-29 cell line, but not in the LS-174T cell line. …”
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