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81
Encapsulation of Vecuronium and Rocuronium by Sugammadex Investigated by Surface-Enhanced Raman Spectroscopy
Published 2025-01-01“…Aiming toward a novel, noninvasive technique, with a real-time potential application in the monitoring of the complexation of steroidal neuromuscular blocker drugs Vecuronium (<b>Vec</b>) and Rocuronium (<b>Roc</b>) with sugammadex (<b>SDX</b>, medication for the reversal of neuromuscular blockade induced by <b>Vec</b> or <b>Roc</b> in general anesthesia), we developed proof-of-principle methodology based on surface-enhanced Raman spectroscopy (SERS). …”
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82
On Erdős sums of almost primes
Published 2024-11-01“…We also give an alternate, probability-theoretic argument related to the Dickman distribution. Here the proof reduces to showing a sequence of integrals converges exponentially quickly $\mathrm{e}^{-\gamma }$, which may be of independent interest.…”
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84
Snapshotting quantum dynamics at multiple time points
Published 2024-10-01“…The two- and three-time QPDs and correlation functions are reconstructed reliably from the experiment, negativity and complex values in the QPDs clearly indicate a contribution of the quantum coherence throughout dynamics.…”
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85
Hardware Efficient Speech Enhancement With Noise Aware Multi-Target Deep Learning
Published 2024-01-01“…Optimisation techniques, including ternary quantisation, structural pruning, efficient sparse matrix representation and cost-effective approximations for complex computations, were implemented to reduce area, memory, and power requirements. …”
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86
Positive Psychological Interventions for Patients with Type 2 Diabetes: Rationale, Theoretical Model, and Intervention Development
Published 2015-01-01“…Current approaches to improve health behaviors in T2D have been variably effective, and successful interventions are often complex and intensive. It is therefore vital to develop interventions that are simple, well-accepted, and applicable to a wide range of patients who suffer from T2D. …”
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87
Differential Proteomic Analysis Predicts Appropriate Applications for the Secretome of Adipose-Derived Mesenchymal Stem/Stromal Cells and Dermal Fibroblasts
Published 2018-01-01“…The proosteogenic effect of DF secretome was validated in vitro on human primary osteoblasts, providing a proof of concept of its osteoinductive potential. …”
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88
A robust, deep learning-based analysis of time-domain signals for NMR spectroscopy
Published 2025-02-01“…Our results confirm that deep learning can efficiently process NMR data to generate final spectra. As a proof of concept, we present the resulting spectra, along with peak lists predicted by supplying only FID input to the deep learning algorithm. …”
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89
Multi-frequency amplitude-programmable metasurface for multi-channel electromagnetic controls
Published 2023-03-01“…It is also possible to carry out multi-bit transmissions by mixing these frequency channels. By introducing complex coding patterns in space domain, it is possible to manipulate EM powers with greater precision. …”
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90
Business Process Modeling Patterns for Blockchain Application Development
Published 2025-01-01“…Our contribution provides a standardized framework for modeling blockchain application requirements, enabling software developers to better understand the complex needs of blockchain applications and design more effective solutions.…”
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91
A SuperLearner-based pipeline for the development of DNA methylation-derived predictors of phenotypic traits.
Published 2025-02-01“…We gathered publicly available DNAm datasets to generate i) a novel childhood epigenetic clock, ii) a reconstructed Hannum adult blood clock, and iii) as a proof of concept, a predictor of polybrominated biphenyl exposure using the three developmental methodologies. …”
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92
SYMBOLIC ANALYSIS OF CLASSICAL NEURAL NETWORKS FOR DEEP LEARNING
Published 2025-03-01“…In this paper, we propose, as a proof of concept, to start the system design by drawing a single neuron. …”
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93
Coherent Control of Single Molecules via Phase-Shaped Two-Photon Excitation at Room Temperature
Published 2025-01-01“…However, for larger functional molecules in condensed phase at room temperature, ensemble measurements do typically not allow exerting full control over competing pathways due to the unavoidable influence of the surrounding (mostly complex) environment. Here, we demonstrate room-temperature coherent control exploiting a nonresonant 2-photon transition into a higher excited state of single conjugated polymer chains embedded in a disordered matrix, including proof-of-principle experiments on bulk films. …”
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94
Site-selective photo-crosslinking for the characterisation of transient ubiquitin-like protein-protein interactions.
Published 2025-01-01“…The stabilised protein complexes can be purified using affinity purification and identified by mass spectrometry. …”
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95
Convergence of Blockchain, IoT, and AI for Enhanced Traceability Systems: A Comprehensive Review
Published 2025-01-01“…Key trends include AI-driven analytics, real-time IoT data collection, and the need for secure, tamper-proof data by BC. However, interoperability, scalability, and standardization challenges hinder adoption. …”
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96
Hybrid Method of Modal Analysis and Laser Shock Scanning to Visualize the Pyroshock Propagation in a Tension Joint
Published 2019-01-01“…The hybrid method developed in this paper demonstrates that it is possible to simulate pyroshock for all the frequency regimes in complex specimens and to evaluate the risk in the time and frequency domain.…”
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97
The neuroendocrine stress-response in insects: the history of the development of the concept
Published 2017-12-01“…The lack of a hypothalamic-pituitary-adrenocortical system in insects was considered a proof of their inability to develop a stress reaction of the warm-blooded animals’ type. …”
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98
The Switchmaze: an open-design device for measuring motivation and drive switching in mice
Published 2024-04-01“…Animals need to switch between motivated behaviours, like drinking, feeding or social interaction, to meet environmental availability, internal needs and more complex ethological needs such as hiding future actions from competitors. …”
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99
Artificial intelligence as a transforming factor in motility disorders–automatic detection of motility patterns in high-resolution anorectal manometry
Published 2025-01-01“…This proof-of-concept study aims to develop and validate an artificial intelligence model for identification and differentiation of disorders of anal tone and contractility in HR-ARM. …”
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100
Simultaneous Inference of Past Demography and Selection from the Ancestral Recombination Graph under the Beta Coalescent
Published 2024-03-01“…The current methods developed to detect such multiple merger events do not account for complex demographic scenarios or recombination, and require large sample sizes. …”
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