Using a Two-Steps Clustering and PCA Analysis for Stratified Chronic Non-Cancer Pain Care: A Retrospective Cross-Sectional Study by Peiró AM, Barrachina J, Escorial M, Aguado I, Margarit C, Grimby-Ekman A

“…Follow-up analyses will support the replicability of this stratified care.Keywords: global pain status, chronic non-cancer pain, clustering analysis, quality of life, stratified care…”
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Effect of ubiquitin-specific proteinase 43 on ovarian serous adenocarcinoma and its clinical significance by Qin Li, Wenhao Li, Jiahao Wang, Wenjing Shi, Taorong Wang

“…Background Ovarian cancer stands as a highly aggressive malignancy. The core aim of this investigation is to uncover genes pivotal to the progression and prognosis of ovarian cancer, while delving deep into the intricate mechanisms that govern their impact.Methods The study entailed the retrieval of RNA-seq data and survival data from the XENA database. …”
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Cancer Burden Disease Attributable to PM2.5 and Health Risk by PM2.5-bound Toxic Species in Two Urban Chilean Municipalities by Ye Li, Franz Muñoz-lbañéz, Ana Maldonado-Alcaíno, Darby Jack, Beizhan Yan, Li Xu, Marco Acuña, Manuel Leiva-Guzman, Ana Valdés, Dante D. Cáceres

“…The AF for cardiopulmonary cancer were 40% (95% CI: 17–57) and 32% (95% CI: 12–46), respectively. …”
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Personalised Lung Cancer Screening (PLuS) study to assess the importance of coexisting chronic conditions to clinical practice and policy: protocol for a multicentre observational... by Yi Guo, Dongyu Zhang, Rafael Meza, Jihyoun Jeon, Dejana Braithwaite, Gerard A Silvestri, Michael K Gould, Jiang Bian, Bruno Hochhegger, Shama D Karanth, Christopher G Slatore, Martin Tammemagi, Mattthew Schabath, Meghann Wheeler, Frederic J Kaye

“…Introduction Lung cancer is the leading cause of cancer death in the USA and worldwide, and lung cancer screening (LCS) with low-dose CT (LDCT) has the potential to improve lung cancer outcomes. …”
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Signatures of H3K4me3 modification predict cancer immunotherapy response and identify a new immune checkpoint-SLAMF9 by Tao Fan, Chu Xiao, Ziqin Deng, Shuofeng Li, He Tian, Yujia Zheng, Bo Zheng, Chunxiang Li, Jie He

“…The deep learning analysis using 12,159 cancer samples from 26 cancer types and 725 cancer samples from 5 immunotherapy cohorts revealed that H3K4me3-RS was significantly correlated with cancer immune tolerance and sensitivity. …”
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Global, regional, and national survey on burden and quality of care index (QCI) of nasopharyngeal cancer: A systematic analysis of the Global Burden of disease study 1990–2019 by Saba Ilkhani, Sahar Saeedi Moghaddam, Delaram Sakhaei, Mohammad-Mahdi Rashidi, Sina Azadnajafabad, Mohammadreza Azangou-Khyavy, Naser Ahmadi, Ozra Tabatabaei-Malazy, Mohammadreza Naderian, Erfan Ghasemi, Parnian Shobeiri, Sahar Mohammadi Fateh, Farzad Kompani, Bagher Larijani, Farshad Farzadfar

“…Background: The epidemiology and inequitable management of nasopharyngeal cancer (NPC) have long been a source of interest due to the malignancy's distinctive geographic distribution. …”
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Prevalência da Exposição à Radiação Solar em Trabalhadores no Brasil: Subsídios para Ações de Prevenção do Câncer de Pele Relacionado ao Trabalho by Fernanda de Albuquerque Melo Nogueira, Giseli Nogueira Damacena, Ubirani Barros Otero, Celia Landmann Szwarcwald

“… Introdução: No Brasil, há pouca informação sobre a prevalência de exposição ocupacional à radiação solar, principal fator de risco para a neoplasia mais frequente no país, o câncer de pele não melanoma. …”
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Concordancia de la clasificación VI-RAD S® y la patología en espécimen de cistectomía en un centro oncológico colombiano by Estefanía Celis-Reyes, Juan C. Londoño-Cano, Andrés Gómez-Hoyos, David Ruiz, Rodolfo Varela, Efraín Betancourt-López

“…Objetivo: El objetivo principal de este estudio es evaluar la concordancia del reporte de la clasificación Vesical Imaging-Reporting and Data System (VI-RADS®) en resonancia magnética (RM) y el reporte de patología del espécimen de cistectomía y definir si este estudio puede considerarse un estándar en el proceso de estadificación en el paciente con diagnóstico clínico de cáncer de vejiga. …”
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L’École de journalisme d’Alger (1964-1990) : les défis d’une formation professionnelle by Chloé Nejma Rondeleux

“…Through a history of the École de journalisme d’Alger (Algiers School of Journalism), from its creation in 1964 to the large-scale reforms of 1990, this article aims to shed light on the journalistic profession in independent Algeria. …”
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Lesiones gástricas preneoplásicas en pacientes con Helicobacter pylori by Ludmila Martínez Leyva, Teresita de Jesús Montero González, Felipe Neri Piñol Jiménez, Amada Belquis Palomino Besada, Lilia Martínez Garrido, Raúl Antonio Brizuela Quintanilla

“…Introducción: Helicobacter pylori es el principal factor de riesgo para el desarrollo de gastritis crónica atrófica y cáncer gástrico de tipo intestinal. …”
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Label-Free Detection of Human Serum Using Surface-Enhanced Raman Spectroscopy Based on Highly Branched Gold Nanoparticle Substrates for Discrimination of Non-Small Cell Lung Cancer by Xiaowei Cao, Zhenyu Wang, Liyan Bi, Jie Zheng

“…SERS spectra were analyzed by principal component analysis (PCA), which was able to distinguish different types of NSCLC. …”
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Targeting necroptosis in MCF-7 breast cancer cells: In Silico insights into 8,12-dimethoxysanguinarine from Eomecon Chionantha through molecular docking, dynamics, DFT, and MEP stu... by Maram B Alhawarri, Mohammad G Al-Thiabat, Amit Dubey, Aisha Tufail, Katreen Banisalman, Ghazi A Al Jabal, Eman Alkasasbeh, Esra'a Ibrahim Al-Trad, Bilal Harieth Alrimawi

“…Breast cancer remains a significant challenge in oncology, highlighting the need for alternative therapeutic strategies that target necroptosis to overcome resistance to conventional therapies. …”
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Liquid chromatography/tandem mass spectrometric characterization of Rhodotorula mucilaginosa GMM natural pigment and its synergistic antitumor effect with γ-radiation: in-vitro and... by Ghada S. Ibrahim, Amal I. Hassan, Manal G. Mahmoud, Mohsen M.S. Asker, Mohamed Marzouk

“…Background/aim Recently, there has been a marked increase in interest toward using microbial resources, especially yeast, to synthesize carotenoids. Ovarian cancer is a major health problem worldwide, as it is the most frequently diagnosed form of cancer in women and contributes significantly to cancer-related deaths. …”
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Caracterización de pacientes con fractura abierta de tibia tratados con fijación externa by Salvio Lázaro López de Quesada, Edilberto Lanfernal Novo, José Luis Nápoles Mengana, Marilaicy Duconger Danger, Celso Suárez Lescay

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Validating a clinically based MS-MLPA threshold through comparison with Sanger sequencing in glioblastoma patients by Halka Lhotska, Karolina Janeckova, Hana Cechova, Jaromir Macoun, Tatiana Aghova, Libuse Lizcova, Karla Svobodova, Lucie Hodanova, Dora Konecna, Jiri Soukup, Filip Kramar, David Netuka, Zuzana Zemanova

“…Results A cohort of 108 patients with histologically and genetically defined glioblastoma was retrospectively examined with methylation-specific Sanger sequencing (sSeq) and methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) methods. …”
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Advanced delivery systems for gene editing: A comprehensive review from the GenE-HumDi COST Action Working Group by Alessia Cavazza, Francisco J. Molina-Estévez, Álvaro Plaza Reyes, Victor Ronco, Asma Naseem, Špela Malenšek, Peter Pečan, Annalisa Santini, Paula Heredia, Araceli Aguilar-González, Houria Boulaiz, Qianqian Ni, Marina Cortijo-Gutierrez, Kristina Pavlovic, Inmaculada Herrera, Berta de la Cerda, Emilio M. Garcia-Tenorio, Eva Richard, Sergio Granados-Principal, Arístides López-Márquez, Mariana Köber, Marijana Stojanovic, Melita Vidaković, Irene Santos-Garcia, Lorea Blázquez, Emily Haughton, Dongnan Yan, Rosario María Sánchez-Martín, Loubna Mazini, Gloria Gonzalez Aseguinolaza, Annarita Miccio, Paula Rio, Lourdes R. Desviat, Manuel A.F.V. Gonçalves, Ling Peng, Cecilia Jiménez-Mallebrera, Francisco Martin Molina, Dhanu Gupta, Duško Lainšček, Yonglun Luo, Karim Benabdellah

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Primary small cell carcinoma of the esophagus: Comparison between a Chinese cohort and Surveillance, Epidemiology, and End Results (SEER) data by Qin Xiao, Haifan Xiao, Shuyu Ouyang, Jinming Tang, Baihua Zhang, Hui Wang

“…Methods Data from 137 Chinese SCCE patients collected from two cancer centers in China were compared with 385 SCCE patients registered in the U.S. …”
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Improving systemic delivery of oncolytic virus by cellular carriers by Ziyi Peng, Muhammad Kalim, Yong Lu

“…Oncolytic virotherapy (OVT) is a promising option for cancer treatment. OVT involves selective oncolytic virus (OV) replication within cancer cells, which triggers anti-tumor responses and immunostimulation. …”
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Breaking the shield of solid tumors: a combined approach for enhanced efficacy of CAR-T cells by Marat Khaliulin, Aygul Valiullina, Alexey Petukhov, Youyong Yuan, Sheila Spada, Emil Bulatov

“…Abstract The use of chimeric antigen receptor (CAR)-T cells has enhanced the range of available therapeutic modalities in the context of cancer treatment. CAR-T cells have demonstrated considerable efficacy in the targeted eradication of blood cancer cells, thereby stimulating substantial interest in the advancement of such therapeutic approaches. …”
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Engineered GM-CSF polarizes protumorigenic tumor-associated macrophages to an antitumorigenic phenotype and potently synergizes with IL-12 immunotherapy by Yue Wang, Kevin Chang, Aslan Mansurov, Jun Ishihara, Seounghun Kang, Trevin Kurtanich, Hye Rin Chun, Anna J Slezak, Lisa R Volpatti, Thomas Wang, Aaron T Alpar, Kirsten C Refvik, O Isabella Hansen, Gustavo J Borjas, Brendan T K Berg, Ha-Na Shim, Kevin T Hultgren, Suzana Gomes, Ani Solanki, Melody A Swartz, Jeffrey A Hubbell

“…Therefore, the rational design of immune modulators that can control the immune suppressive properties of TAMs and polarize them, as well as dendritic cells (DCs), toward a more proinflammatory phenotype is a principal objective in cancer immunotherapy.Methods Here, using a protein engineering approach to enhance cytokine residence in the tumor microenvironment, we examined combined stimulation of the myeloid compartment via tumor stroma-binding granulocyte–macrophage colony-stimulating factor (GM-CSF) to enhance responses in both DCs and T cells via stroma-binding interleukin-12 (IL-12). …”
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