Investigation of Phagocyte Functions in Pseudomonas-Colonized Cystic Fibrosis Patients by Handan Duman Şenol, Meral Barlık, Ezgi Topyıldız, Figen Gülen, Güzide Aksu, Necil Kütükçüler, Esen Demir, Neslihan Edeer Karaca

“…Neutrophils are the most effective cells in the eradication of bacterial infections such as Pseudomonas aeruginosa. The aim of the present study was to investigate the phagocyte functions in pseudomonas colonized CF patients. …”
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Tuning antibody stability and function by rational designs of framework mutations by Joseph C. F. Ng, Alicia Chenoweth, Maria Laura De Sciscio, Melanie Grandits, Anthony Cheung, Tooki Chu, Alexandra McCraw, Jitesh Chauhan, Yi Liu, Dongjun Guo, Semil Patel, Alice Kosmider, Daniela Iancu, Sophia N. Karagiannis, Franca Fraternali

“…These approaches, however, often focus on the antibody complementarity-determining region (CDR) whilst ignoring the immunoglobulin framework (FW), which provides structural rigidity and support for the flexible CDR loops. Here we present an integrated computational-experimental workflow, combining static structure analyses, molecular dynamics simulations and in vitro physicochemical and functional assays to generate rational designs of FW mutations for modulating antibody stability and activity. …”
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Satisfaction with Nursing Care and the Functional Consequences of Pain in Neurosurgical Patients by Elżbieta Bartoń, Robert Ślusarz, Ewa Guz, Józef Jasik, Krzysztof Turowski, Anna Mazur, Danuta Zarzycka

“…The aim of the work is to present what dimension of satisfaction from nursing is dominant among patients with lumbar spine pain syndrome and to determine whether their assessment depends on the severity of functional consequences of pain. …”
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CALCULATION OF THE COST OF THE DEVELOPED FUNCTIONAL DRINK BASED ON MATCHA TEA by V. S. Paukova

“…The purpose of the work is to calculate the cost of the developed functional drink based on mast tea. Matcha is a Japanese powdered green tea. …”
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Functional connectivity abnormalities in clinical variants of progressive supranuclear palsy by Irene Sintini, Farwa Ali, Yehkyoung Stephens, Heather M. Clark, Julie A. Stierwalt, Mary M. Machulda, Ryota Satoh, Keith A. Josephs, Jennifer L. Whitwell

“…We sought to determine whether disruptions in functional connectivity within this PSP network measured using resting-state functional MRI (rs-fMRI) differed between PSP-Richardson’s syndrome (PSP-RS) and the cortical and subcortical clinical variants of PSP. …”
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Human phospholipases A2: a functional and evolutionary analysis by I. I. Turnaev, M. E. Bocharnikova, D. A. Afonnikov

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How vanadium and manganese compounds impact cardiac mitochondrial function by Connor C. Dolan, Luke A. Whitcomb, Edgar Del Carpio, Edgar Del Carpio, Lilliana Rose, Adam J. Chicco, Debbie C. Crans, Debbie C. Crans

“…Many studies have indicated that these metals elicit their effects in part by influencing mitochondrial function, with potential variations due to their redox properties and complexation.MethodsTo better understand these relationships, we investigated the effects of vanadium and manganese salts (VIVOSO4, NaVVO3, MnIICl2) and acetoacetate (Hacac) complexes (VIVO(acac)2 and MnII(acac)2) on murine cardiac mitochondrial function. …”
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Resting-State Functional MRI in Dyslexia: A Systematic Review by Bruce Martins, Isabel A. B. Verrone, Mariana M. I. Sakamoto, Mariana Y. Baba, Melissa E. Yvata, Katerina Lukasova, Mariana P. Nucci

“…<b>Background/Objectives:</b> The present review addresses and systematically analyses the most frequently reported neuropsychological and functional connectivity (FC) alterations in individuals with dyslexia compared to controls. …”
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Genotypic, functional, and phenotypic characterization in CTNNB1 neurodevelopmental syndrome by Nina Žakelj, David Gosar, Špela Miroševič, Stephan J. Sanders, Alicia Ljungdahl, Sayeh Kohani, Shouhe Huang, Lok I Leong, Ying An, Miou-Jing Teo, Fiona Moultrie, Roman Jerala, Duško Lainšček, Vida Forstnerič, Petra Sušjan, Leszek Lisowski, Andrea Perez-Iturralde, Jasna Oražem Mrak, Ho Yin Edwin Chan, Damjan Osredkar

“…One missense variant demonstrated a gain-of-function effect. Dominant-negative variants were not clearly associated with a distinct phenotype; however, those with missense variants presented a milder phenotype, including earlier achievement of independent walking, fewer motor impairments, better conceptual and social skills, improved communication, and fewer feeding difficulties. …”
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Effects of Diethylstilbestrol on the Structure and Function of the Spleen in Male Golden Hamsters by Jian Li, Ruiping Xu, Qingwei Wang, Xue Bai, Yanhua Su, Yaoxing Chen, Jing Cao

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Diversity and function of soluble heterodisulfide reductases in methane-metabolizing archaea by Xingyu Lyu, Hang Yu, Yahai Lu

“…In this study, we investigated the functional diversity and evolutionary dynamics of HdrA in methane-metabolizing archaea. …”
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Neuropsychiatric Approaches to Essential and Functional Tremor: A Comparative Study by Balal M, Çakmak S, Erdem M, Demirkiran M

“…Mehmet Balal,1 Soner Çakmak,2 Miray Erdem,3 Meltem Demirkiran4 1Department of Neurology, Çukurova University, Adana, 01330, Türkiye; 2Department of Psychiatry, Çukurova University, Adana, 01330, Türkiye; 3Department of Neurology, University of Health Sciences, Adana, 1370, Türkiye; 4Independent Researcher, Adana, 1120, TurkeyCorrespondence: Mehmet Balal, Department of Neurology, Çukurova University, Adana, 01330, Türkiye, Tel +90505 544 69 49, Email memet_balal@hotmail.comPurpose: Differentiating essential tremor (ET) from functional tremor (FT) remains a challenge due to their overlapping clinical presentations. …”
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Evaluation of Hepatosplenomegaly and Liver Function Tests in 102 Brucellosis Cases by Serhat UYSAL, Fatih DANA, Meltem IŞIKGÖZ, Erkan KISMALI, Oğuz Reşat SİPAHİ, Hüsnü PULLUKÇU, Tansu YAMAZHAN, Sercan ULUSOY

“…Mean age of the cases without a remarkable liver pathology was 51.1 ± 14.9; whereas, mean age of the rest of the cases was 44.3 ± 16.3 (p= 0.035). Liver function tests improved in all cases with treatment. …”
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Neuropad Assessment of Sudomotor Function Across Glycemic Levels in Adults by Wang Q, Yang Z, Zhao S, Tian C, Zhang P, Li R

“…The slope (Slope[1– 10]) was used as a quantitative measure of sudomotor function.Additional data included age, BMI (body mass index), FPG (fasting plasma glucose), HbA1c (hemoglobin A1c), blood pressure, lipid levels, and liver and kidney function. …”
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Oak Acorns as Functional Foods: Antioxidant Potential and Safety Assessment by Vesna Stankov Jovanović, Vladan Djurić, Violeta Mitić, Ana Barjaktarević, Snežana Cupara, Marija Ilić, Jelena Nikolić

“…The results confirm that acorns of <i>Quercus robur</i>, especially in their native flour form, are rich in antioxidants, naturally gluten-free, and safe when thermally processed, making them a strong candidate for use in functional foods.…”
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SUBSTANTIATION OF THE DAIRY-PLANT ADDITIVES TECHNOLOGY FOR USE IN FUNCTIONAL PRODUCTS by V. Kolesnyk, V. Polupan, N. Penkina, S. Sorokina, A. Penkin, I. Bushtakov, O. Veretennikov

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FUNCTIONAL POLYMORPHISM OF THE PRO-INFLAMMATORY CYTOKINE GENES IN PULMONARY TUBERCULOSIS by E. G. Churina, O. I. Urazova, V. V. Novitsky, A. V. Sitnikova, S. E. Barmina

“…In the present time, incidence of pulmonary tuberculosis (TB) becomes broader, due to spreading resistance of Mycobacterium tuberculosis (MBT) to anti-tuberculosis drugs and infection with highly virulent strains of M. tuberculosis. …”
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Functional Outcome of Bimalleolar Ankle Fractures – A Prospective Study by R. Sahaya Jose, Shaheen Hameed, N. Kattu Bava, M. Syed Moosa

“…Based on the fracture pattern, the patients were planned for surgical fixation with appropriate implants. Results: In our present study of 40 patients, we assessed the functional outcome based on Baird and Jackson’s scoring system. …”
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The origin of synthons and supramolecular motifs: beyond atoms and functional groups by Rahul Shukla, Emmanuel Aubert, Mariya Brezgunova, Sébastien Lebègue, Marc Fourmigué, Enrique Espinosa

“…Geometrical characterizations and topological analyses of the electron density ρ(r) and its negative Laplacian function [L(r) = −∇2ρ(r)] indicate that all the bonding interactions forming the motifs are driven by local electrophilic...nucleophilic interactions between complementary charge concentration (CC) and charge depletion (CD) sites present in the valence shells of the atoms, regardless of the atoms and functional groups involved. …”
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Effects of glycyrrhizinic acid on neuromotor function in leptin-resistant mice by T. M. Matuzok, V. A. Prikhodko, S. M. Napalkova, O. V. Buyuklinskaya, S. V. Okovityi

“…To study the effects of course administration (1 month) of glycyrrhizinic acid (GA) (20 mg/kg/d) on neuromotor function in female leptin-resistant diabetic db/db mice of different ages using stimulation electroneuromyography (ENMG).Materials and methods. …”
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