Identifying common factors of functioning, participation and environment amongst adults requiring specialist oral health care using the International Classification of Functioning,... by Alison Dougall, Francisca Martinez Pereira, Gustavo Molina, Caroline Eschevins, Blánaid Daly, Denise Faulks

“…Impaired body functions included 'ingestion functions', 'energy and drive functions' and 'emotional functions'. …”
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Severe Dental Disease as a Presenting Sign of Relapsed 6q24-Related Transient Neonatal Diabetes Mellitus by Anna Delamerced, Lauren J. Massingham, Jose Bernardo Quintos

“…The most common cause of TNDM is a chromosome 6q24 mutation that affects pancreatic β-cell function. Reports of relapse have been limited. We describe a case of an adolescent female with TNDM due to 6q24 hypomethylation who relapsed at 15 years of age with severe dental disease as the presenting sign.…”
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Fever of Unknown Origin as a Sole Presentation of Subacute Thyroiditis in an Elderly Patient: A Case Report with Literature Review by Rishi Raj, Srujana Yada, Aasems Jacob, Dileep Unnikrishnan, Wael Ghali

“…An 80-year-old Caucasian male presented with fever of 3-week duration. Outpatient workup for infectious etiologies was negative and due to persistent fever, he was hospitalized for further evaluation of fever of unknown origin (FUO). …”
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T cells in ARAP-deficient mice present defective T cell receptor signaling and reduced severity in an experimentally-induced autoimmune disease by Jee-Hae Kim, Seung Hee Jung, Chohee Park, Jong Ran Lee

“…These results strongly suggest that ARAP positively regulates T cell function, while ARAP deficiency in T cells reduces the severity and incidence of EAE.…”
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Cardiac Tamponade as the Initial Presentation of Coexistent Systemic Lupus Erythematosus and Addison’s Disease: A Case Report and Literature Review by Abdullah Abu Keshek MD, Mohammad Hakam Shehadeh MD, Mohammed M. Salahaldin MD, Salem K. Qupp MD, Omar Mohammad Marouf MD, Ahmad A. Dallashi MD

“…Its coexistence with primary adrenal insufficiency (Addison’s disease) represents an even rarer clinical scenario. We present the case of a 28-year-old female who presented with cardiac tamponade as the initial presentation of concurrent SLE and Addison’s disease. …”
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Identification of genetically engineered strategies to manipulate nano-platforms presenting immunotherapeutic ligands for alleviating primary ovarian insufficiency progression by Guannan Zhou, Yuanyuan Gu, Menglei Zhang, Jingxin Ding, Guanming Lu, Keqin Hua, Fang Shen

“…Abstract Primary ovarian insufficiency (POI) is a pathological condition characterized by the early loss of functional ovarian follicles, leading to infertility and systemic consequences affecting reproductive, skeletal, cardiovascular, and neurocognitive helath. …”
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Refractory Classical Hodgkin Lymphoma Presenting with Atypical Cutaneous Involvement and Diagnosis of ZZ Phenotype Alpha-1 Antitrypsin Deficiency by Mohamad Khawandanah, Teresa Kraus, Mohamad Cherry

“…Bleomycin was not given secondary to poor pulmonary function tests. His treatment was complicated after AVD with multiple pneumothoraces which unmasked the diagnosis of ZZ phenotype alpha-1 antitrypsin (ATT) deficiency. …”
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Aborted Sudden Cardiac Death in a Female Patient Presenting with Takotsubo-Like Cardiomyopathy due to Epicardial Coronary Vasospasm by Sorin Giusca, Tom Eisele, Peter Nunninger, Benedikt Münz, Grigorios Korosoglou

“…Echocardiography suggested LV apical ballooning with severely impaired LV-function, so that takotsubo cardiomyopathy was suspected. …”
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From Molecular Therapies to Lysosomal Transplantation and Targeted Drug Strategies: Present Applications, Limitations, and Future Prospects of Lysosomal Medications by Adel A. Alhowyan, Gamaleldin I. Harisa

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Presenting a Stochastic Model of Simultaneous Planning Problem of Distribution and Subtransmission Network Development considering the Reliability and Security Indicators by Seyed Hossein Moayed, Hosein Hasan Shahi, Mohammadreza Akbarizadeh, Morteza Jadidoleslam, Arash Aghatehrani, Afshin Pirouzi

“…Therefore, in this study, the stochastic problem model of simultaneous planning of distribution and super distribution network development considering the reliability and security indicators is presented. The aforementioned problem is in the form of an optimization problem whose objective function is to minimize the costs of construction, replacement, operation, maintenance, reliability, and security. …”
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Muse Cells: Nontumorigenic Pluripotent Stem Cells Present in Adult Tissues—A Paradigm Shift in Tissue Regeneration and Evolution by Ariel A. Simerman, Julia D. Phan, Daniel A. Dumesic, Gregorio D. Chazenbalk

“…Muse cells have a high capacity for homing into damaged tissue and spontaneous differentiation into cells of compatible tissue, leading to tissue repair and functional restoration. The ability of Muse cells to restore tissue function may demonstrate the role of Muse cells in a highly conserved cellular mechanism related to cell survival and regeneration, in response to cellular stress and acute injury. …”
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Horseshoe kidney presenting with features of left ureteropelvic junction obstruction—insights into management: a case report and review of the literature by Philipo Felix Mwita, Charles John Nhungo, Amini Mitamo Alexandre, Sylvia Bedas Nsato, Theofilo Mmbando, Gabriel Mtaturu, Obadia Nyongole, Charles A. Mkony

“…This case explores the etiology, clinical presentation, and surgical management of UPJO in a patient with a horseshoe kidney, highlighting the critical role of urologists in addressing these anatomical and functional complexities. …”
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Interaction between glutathione S‐transferase M1‐null/present polymorphism and adjuvant chemotherapy influences the survival of breast cancer by Shuang Li, Guan‐Tian Lang, Ying‐Zhou Zhang, Ke‐Da Yu, Zhi‐Ming Shao, Qiang Zhang

“…The null polymorphism of GSTM1 gene results in a thorough absence of the enzyme function. Our study was to evaluate the association between GSTM1 null/present polymorphism and chemotherapy treatment outcome in breast cancer patients. …”
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Clinical presentation and predictors of hospital mortality of diphtheria in Nigeria, July 2023 to April 2024: a single-center study by Abdurrazzaq Alege, Olayinka Rasheed Ibrahim, Rasheedat Mobolaji Ibraheem, Olajide Aladesua, Abubakar Sani Lugga, Yunusa Yusuf Yahaya, Abdallah Sanda, Bello Muhammed Suleiman

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From Clinical Presentation to Genetic Confirmation: A Case of L2HGDH-Related Leukodystrophy in an 11-Year-Old by Negareh Poursalehi, Mojtaba Movahedinia, Mohammad Hossein Mohammadi, Mohamammad Ebrahim Ghanei, Mohammad Yahya Vahidi Mehrjerdi, Seyed Mehdi Kalantar

“…Leukodystrophies cause a progressive loss of neurological function in infants, children, and sometimes adults. …”
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A secreted Tapasin isoform impairs cytotoxic T lymphocyte recognition by disrupting exogenous MHC class I antigen presentation by Robyn P. Seipp, Robyn P. Seipp, Guillaume Hoeffel, Alexander R. Moise, Alexander R. Moise, Siri Lok, Siri Lok, Anne-Claire Ripoche, Concepción Marañón, Anne Hosmalin, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies

“…Endogenous and exogenous antigen processing and presentation through the MHC class I peptide-loading complex (PLC) are essential for initiating cytotoxic T lymphocyte responses against pathogens and tumors. …”
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Postmenopausal women with higher TSH values within the normal range present improved handgrip strength: a pilot study by Panagiota Chatzivasileiou, Eleni Armeni, Peter Chedraui, Loraina Kontou, Areti Augoulea, Anastasia Palaiologou, George Kaparos, Konstantinos Panoulis, Andreas Alexandrou, Nikolaos Vlachos, Irene Lambrinoudaki

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Extracellular Vesicles Present in Bone Marrow Mesenchymal Stromal/Stem Cell Conditioned Media Restore Spermatogenesis in Azoospermic Mice by Rano Zhankina, Afshin Zare, Alireza Afshar, Arezoo Khoradmehr, Mohammad Reza Dorvash, Farhad Rahmanifar, Nader Tanideh, Omid Koohi Hosseinabadi, Ali Arabi Monfared, Shahrokh Zare, Nadiar Mussin, Asset Askerovich Kaliyev, Ulanbek Zhanbyrbekuly, Amin Tamadon

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Clinical presentation and outcome of Graves disease in pediatric patients with and without type 1 diabetes: a retrospective cohort study by Yi-Hsin Wu, Yi-Hsin Wu, Lu-Ting Wang, Yann-Jinn Lee, Yann-Jinn Lee, Yann-Jinn Lee, Yann-Jinn Lee, Yann-Jinn Lee, Chi-Yu Huang, Yu-En Kao, Chao-Hsu Lin, Chao-Hsu Lin, Bi-Wen Cheng, Fu-Sung Lo, Fu-Sung Lo, Wei-Hsin Ting, Wei-Hsin Ting

“…However, few studies have explored the clinical presentation and outcomes of Graves disease (GD) in T1D patients. …”
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Group 2 innate lymphoid cells boost CD8+ T-cell activation in anti-tumor immune responses by Jing Wen, Shipeng Cheng, Ran Wang, Yuying Huang, Long Xu, Liyan Ma, Zhiyang Ling, Jinfu Xu, Deping Zhao, Yaguang Zhang, Bing Sun

“…In this study, we showed that IL-33-activated ILC2s could boost CD8+ T-cell function through direct antigen cross-presentation. …”
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