Reconstructive surgery to preserve ankle function in a 5-year-old girl with bilobed distal tibia in an unclassified case of tibial hemimelia: a case report by Alireza Ghaznavi, Miad Nosratpour, Seyed Mohammadmisagh Moteshakereh, Ava Parvandi, Shayan Amiri

“…A staged approach to reconstructive surgery was advocated to ensure the preservation of ankle function and to prevent extreme procedures such as amputation. …”
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Dietary Fish Meal Level and a Package of Choline, β-Glucan, and Nucleotides Modulate Gut Function, Microbiota, and Health in Atlantic Salmon (Salmo salar, L.) by Åshild Krogdahl, Elvis M. Chikwati, Aleksei Krasnov, Anusha Dhanasiri, Gerd M. Berge, Violetta Aru, Bekzod Khakimov, Søren Balling Engelsen, Hilde Vinje, Trond M. Kortner

“…An average choline requirement of 3.5 g/kg was indicated for Atlantic salmon at the present life stage and under the present condition.…”
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Protocol for fabricating a reusable plate-well insert with a 3D-printed mounter and hydrogel scaffolds for 3D cell culture and functional assays by Saloua Saghir, Jana Hlinkova, Athina Samara, Giuseppe Schiavone

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Census of Lyα Emission from ∼600 Galaxies at z = 5–14: Evolution of the Lyα Luminosity Function and a Late Sharp Cosmic Reionization by Yuta Kageura, Masami Ouchi, Minami Nakane, Hiroya Umeda, Yuichi Harikane, Shintaro Yoshiura, Kimihiko Nakajima, Hidenobu Yajima, Tran Thi Thai

“…Notably, this study presents the first constraints on the Ly α luminosity function at z  ∼ 8–14. …”
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Structural and functional analysis of the symmetrical Type I restriction endonuclease R.EcoR124I<sub>NT</sub> by James E Taylor, Anna Swiderska, Jean-Baptiste Artero, Philip Callow, Geoff Kneale

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A new numerical technique for the solution of time-fractional nonlinear Klein–Gordon equation involving Atangana–Baleanu derivative using cubic B-spline functions by Shaheen Muserat, Abbas Muhammad, Abdullah Farah Aini, Hamed Yasser Salah

“…This equation has been solved using a variety of techniques. The current work presents a numerical approach that uses cubic B-spline (CBS) functions to solve the KGE involving Atangana–Baleanu fractional derivative. …”
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СURRENT CONCEPTS OF THE ROLE OF ALTERED BLOOD-BRAIN BARRIER RESISTANCE IN THE PATHOGENESIS OF CNS DISORDERS. PART II: FUNCTIONS AND MECHANISMS OF THE BLOOD-BRAIN BARRIER DAMAGE by D. V. Blinov

“…The understanding  of functions, transport  mechanisms and mechanisms of damage  of the BBB in pathologic  settings  would allow determining  promising  ways to improve the efficacy of current diagnostics  and treatment  options.  …”
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Analysis of a heterogeneous functionally graded material with a spherical void exposed to time-dependent ramp-type heating according to the TPL heat conduction model by Sami F. Megahid

“…Their distinctive architecture facilitates improved mechanical characteristics, thermal resilience, and operational efficacy in domains such as aerospace, biomedical, and automotive engineering. This study presents a novel three-phase-lag (TPL) thermal conductivity model and examines the thermoelastic behavior of a functionally graded medium featuring a spherical void. …”
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Understanding parents’ experiences of disease course and influencing factors: a 3-year follow-up qualitative study among parents of children with functional abdominal pain by Mette Brekke, Anne Brodwall

“…Objective Functional abdominal pain is a common symptom in children and adolescents. …”
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A non-classical PUF family protein in oomycetes functions as a pre-rRNA processing regulator and a target for RNAi-based disease control. by Hui Feng, Tianli Liu, Chuanxu Wan, Zhichao Zhang, Yuanchao Wang, Xiaobo Zheng, Jie Wang, Wenwu Ye

“…Given the conserved role of Puf4 in oomycete pathogenicity, we developed the first nano-material-free dsRNA delivery system via zoospore-specific uptake, effectively attenuating virulence in Pythium aphanidermatum and Ph. sojae through RNAi targeting Puf4. This study presents novel findings on structural and functional conservation of Puf4 and offers a promising RNAi-based strategy for controlling oomycete plant diseases.…”
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Advancing autonomous vehicle safety assessment: A novel methodology for moving from functional to concrete scenarios using kinetic 3D-LiDAR and SHAP by Minhee Kang, Saeyan Eom, Keeyeon Hwang

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The Effects of Combined Exercise Training (Resistance-Aerobic) on Serum Kinesin and Physical Function in Type 2 Diabetes Patients with Diabetic Peripheral Neuropathy (Randomized Co... by Seyedeh Hoda Seyedizadeh, Sadegh Cheragh-Birjandi, Mohammad Reza Hamedi Nia

“…This in turn results in imbalance leading to the diabetic patients’ daily activity disparity. The present investigation was conducted to specifically study the effects of combined training (resistance-aerobic) on serum kinesin-1 and physical function in type 2 diabetes patients with diabetic peripheral neuropathy. 24 diabetic neuropathic females were randomly to be selected out and divided into two experimental and control groups. …”
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Polydopamine-functionalized calcium-deficient hydroxyapatite 3D-printed scaffold with sustained doxorubicin release for synergistic chemo-photothermal therapy of osteosarcoma and a... by Lu Wang, Zihan Dai, Jianqiang Bi, Yunzhen Chen, Ziyu Wang, Zhenqian Sun, Zhongjie Ji, Hongliang Wang, Yan Zhang, Limei Wang, Junjie Mao, Junxing Yang

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A comparison study on structure-function relationship of polysaccharides obtained from sea buckthorn berries using different methods: antioxidant and bile acid-binding capacity by Qiaoyun Li, Zuman Dou, Qingfei Duan, Chun Chen, Ruihai Liu, Yueming Jiang, Bao Yang, Xiong Fu

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Effects of benzoxazine resin on property enhancement of shape memory epoxy: A dual function of benzoxazine resin as a curing agent and a stable network segment by T. Tanpitaksit, C. Jubsilp, S. Rimdusit

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Production of Functional Vinegar Enriched with γ-Aminobutyric Acid through Serial Co-Fermentation of Lactic Acid and Acetic Acid Bacteria Using Rice Wine Lees by Yun-Ho Park, Min-Jeong Kwon, Dong-Min Shin, Sam-Pin Lee

“…Functional vinegar with high γ-aminobutyric acid (GABA) content was manufactured through a two-stage serial co-fermentation of rice wine lees, a by-product of Korean rice wine, using lactic acid bacteria (LAB) and acetic acid bacteria (AAB). …”
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CD8+ regulatory T cells, and not CD4+ T cells, dominate suppressive phenotype and function after in vitro live Mycobacterium bovis-BCG activation of human cells. by Mardi C Boer, Krista E van Meijgaarden, Simone A Joosten, Tom H M Ottenhoff

“…Still, in settings of infectious diseases and vaccination, most studies have focused on CD4+ regulatory T cells, and not CD8+ regulatory T-cells. Here, we present a comparative analysis of the suppressive phenotype and function of CD4+ versus CD8+ T cells after in vitro live BCG activation of human cells. …”
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Training Cognitive Functions Using DUAL-REHAB, a New Dual-Task Application in MCI and SMC: A Study Protocol of a Randomized Control Trial by Elisa Pedroli, Francesca Bruni, Valentina Mancuso, Silvia Cavedoni, Francesco Bigotto, Jonathan Panigada, Monica Rossi, Lorenzo Boilini, Karine Goulene, Marco Stramba-Badiale, Silvia Serino

“…Results: The expected outcome is an improvement in cognitive and motor functioning after the experimental training. Conclusion: This study will advance the literature on non-pharmacological interventions and innovative technological tools for cognitive trainings in the early stages of cognitive decline.…”
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Pulse-Driven Internal Resistance Dynamics Enable Dual-Function Lithium-Plating Diagnosis and Longevity Enhancement in V2G-Optimized Lithium-Ion Batteries by Letong Li, Yanan Wang, Dongliang Guo, Xuebing Han, Hewu Wang, Lei Sun, Minggao Ouyang

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Aqueous extracts of Elsholtzia ciliata and Hovenia dulcis ameliorate loperamide-induced constipation in mice by promoting intestinal peristalsis and barrier function and the abunda... by Junnan Wu, Junnan Wu, Qilei Xin, Shuo Wang, Xu Zhang, Chunping Jiang, Chunping Jiang

“…ObjectiveThe aims of the present study were to determine the efficacy of edible traditional Chinese medicines (ETCMs) in treating constipation, verify their laxative effects, and conduct preliminary investigations into their mechanisms of action.MethodsICR mice were treated with loperamide to induce constipation, and various fecal parameters, including fecal volume, water content, and intestinal transport function, were measured in these constipation model mice to screen for ETCMs with laxative properties. …”
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